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| 1 | Adenocarcinoma of gastric cardia in the elderly: Surgical problems and prognostic factors显示文摘AIM: To analyze retrospectively, our results about patients who underwent surgical treatment for adenocarcinoma of the cardia in relation to age, in order to evaluate surgical problems and prognostic factors.METHODS: From January 1987 to March 2003, 140 patients with adenocarcinoma of the cardia underwent resection in the authors' institution. They were divided into three groups with regard to age. Patients <70 and >60 year old (31) were excluded; we also excluded 18 out of 109 patients with poor general status or systemic metastases. So, we compared 51 elderly (≥ 70 year old)and 58 younger patients (≤ 60 year old). The treatment was esophagectomy for type Ⅰ tumors, and extended gastrectomy and distal esophagectomy for type Ⅱ and Ⅲ lesions.RESULTS: Laparotomy was carried out in 91 patients (83.4%), 38 in the elderly (74.5%) and 53 in younger patients (91.3%, P<0.05). Primary resection was performed in 811 cases (89%) without significant differences between the two groups. Postoperative death was higher in the elderly (12.1%) than the other group (4.1%, P<0.05), while morbidity was similar in both groups. A curative resection (R0) was performed in 59 patients (72.8%), 69.6% in the elderly and 75% in the younger group (P>0.05). The overall 3- and 5-year survival rates were 26.7% and 117.8% respectively for the elderly and 40.7% and 35.1% respectively for younger patients (P = 0.1544). Survival rates were significantly associated with R0 resection,pathological node-positive category and tumor differentiation in both groups.CONCLUSION: As the age of the general population increases, more elderly patients with gastric cardia cancer will be candidates for surgical resection. Age alone should not preclude surgical treatment in elderly patients with gastric cardia cancer and a tumor resection can be carried out safely. Certainly, we should take care in defining the surgical treatment in elderly patients, particularly as regarding the surgical approach; although the surgical approach does not influence the survival rate, the transhiatal way still remains the best one due, to the lower incidence of respiratory morbidity and thoracic pain. | Natale Di Martino Giuseppe Izzo Angelo Cosenza Guido Cerullo Francesco Torelli Antonio Brillantino Alberto del Genio | 2005 | World Journal of Gastroenterology2005，11，33： | 5 |
| 2 | Costs of laparoscopic and open liver and pancreatic resection:A systematic review显示文摘AIM:To study costs of laparoscopic and open liver and pancreatic resections,all the compiled data from available observational studies were systematically reviewed.METHODS:A systematic review of the literature was performed using the Medline,Embase,Pub Med,and Cochrane databases to identify all studies published up to 2013 that compared laparoscopic and open liver[laparoscopic hepatic resection(LLR)vs open liver resection(OLR)]and pancreatic[laparoscopic pancreatic resection(LPR)vs open pancreatic resection]resection.The last search was conducted on October 30,2013.RESULTS:Four studies reported that LLR was associated with lower ward stay cost than OLR(2972 USD vs 5291 USD).The costs related to equipment(3345USD vs 2207 USD)and theatre(14538 vs 11406)were reported higher for LLR.The total cost was lower in patients managed by LLR(19269 USD)compared to OLR(23419 USD).Four studies reported that LPR was associated with lower ward stay cost than OLR(6755vs 9826 USD).The costs related to equipment(2496USD vs 1630 USD)and theatre(5563 vs 4444)were reported higher for LPR.The total cost was lower in the LPR(8825 USD)compared to OLR(13380 USD).CONCLUSION:This systematic review support the economic advantage of laparoscopic over open approach to liver and pancreatic resection. | Paolo Limongelli Chiara Vitiello Andrea Belli Madhava Pai Salvatore Tolone Gianmattia del Genio Luigi Brusciano Giovanni Docimo Nagy Habib Giulio Belli Long Richard Jiao Ludovico Docimo | 2014 | World Journal of Gastroenterology2014，20，46： | 5 |
| 3 | Short-term outcomes after rehabilitation treatment in patients selected by a novel rehabilitation score system ( Brusciano score ) with or without previous stapled transanal rectal resection ( STARR ) for rectal outlet obstruction显示文摘 | Brusciano L Limongelli P del Genio G | 2013 | International Journal of Colorectal Disease2013，28，6： | 1 |
| 4 | Surface observed global land precipitation variations during 1900-1988 显示文摘 | Dai A Ftmg I Y Del Genio A D | 1997 | J Climate1997，10，： | 1 |
| 5 | Relationships between lightning and properties of convective cloud clusters显示文摘 | FUTYAN J M DEL Genio A D | 2007 | Geophysical Research Letters2007，34，15： | 1 |
| 6 | Non alcoholic fatty liver disease in young adult severely obese non - diabetic patients in South Italy 显示文摘 | Colicchio P Tarantino G del Genio F | 2005 | Ann Nutr Metab2005，49，： | 1 |
| 7 | Useful parameters helping proctologists to identify patients with defaecatory disorders that may be treated with pelvic floor rehabilitation显示文摘 | Brusciano L Limongelli P del Genio G | 2007 | Tech Coloproctol2007，11，1： | 1 |
| 8 | All scale-free networks are sparse显示文摘 | GENIO C I GROSS T BASSLER K E | | 0，，107： | 1 |
| 9 | Metabolic surgery: the role of the gastrointestinal tract in diabetes mellitus 显示文摘 | Rubino F R'Bibo S L del Genio F | 2010 | Nat Rev Enclocrinol2010，6，2： | 1 |
| 10 | Short-term outcomes af- ter rehabilitation treatment in patients selected by a novel rehabilita- tion score system ( Brusciano score ) with or without previous stapled transanal rectal resection (STARR)for rectal outlet obstruction 显示文摘 | Brusciano L Limongelli P Del Genio G | 2013 | Int J Colorectal Dis2013，28，6： | 1 |
| 11 | Impact of total fundopli-cation on esopHageal transit : analysis by combined multichannelintraluminal impedance and manometry 显示文摘 | Del Genio G Tolone S Del Genio F | 2012 | J Clin Gastroenterol2012，46，1： | 1 |
| 12 | Metabolic surger- y: the role of the gastrointestinal tract in diabetes mellitus 显示文摘 | Rubino F Genio F Mazumdar M | 2010 | Nat Rev Endocrinology2010，6，： | 1 |
| 13 | Bacterial virulence inthe etiology of periodontal diseases显示文摘 | Sbordone L Di Genio M Bortolaia C | 2000 | Minerva Stomatol2000，49，10： | 1 |
| 14 | The dust settles on water vapor feedback 显示文摘 | Del Genio A D | 2002 | Science2002，296，： | 1 |
| 15 | Impact of total fundoplication on esophageal transit: analysis by combined multichannel intraluminal impedance and manometry显示文摘 | Del Genio G Tolone S Del Genio F | 2012 | J Clin Gastroenterol2012，46，1： | 1 |
| 16 | Useful parameters helping proctologists to identify patients with defaecatory disorders that may be treated with pelvic floor rehabilitation 显示文摘 | Brusciano L Limongelli P del Genio G | 2007 | Tech Coloproctol2007，11，1： | 1 |
| 17 | The temperature dependence of the liquid water path of low clouds in the Southern Great Plains显示文摘 | Del Genio A D A B Wolf | 2000 | J Climate2000，13，： | 1 |
| 18 | Sleeve gastrectomy and de- velopment of 'de novo' gastroesophageal reflux显示文摘 | Del Genio G Tolone S Limongelli P | 2014 | Obes Surg2014，24，1： | 1 |
| 19 | All scale-free networks are sparse显示文摘 | Genio C I Gross T Bassler K E | 2011 | Physical Review Letters2011，107，17： | 1 |
| 20 | GCM simula- tions of the aerosol indirect effect~ sensitivity to cloud parame terization and aerosol burden显示文摘 | MENON S DEL GENIO A D KOCH D | 2002 | Journal of Atmospheric Sci- ences2002，59，3： | 1 |
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