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您的检索式：作者名="Geng Fawei"
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| 1 | Geniposide protects human neuroblastoma SH-SY5Y cells against corticosterone-induced injury显示文摘In vitro cultured human neuroblastoma SH-SY5Y cells were pretreated with 50 or 5 μg/mL geniposide for 12 hours and exposed to 400 μmol/L corticosterone. Corticosterone exposure in cultures not pretreated with geniposide resulted in inhibited cell growth, reduced cell survival, and increased P53 and P21 protein expression. However, in geniposide pretreated SH-SY5Y cells, cell viability and the number of cells in the G2 phase of the cell cycle were significantly increased, P21 and P53 protein expression was reduced, and cell apoptosis was inhibited following corticosterone exposure. These results indicate that geniposide can protect SH-SY5Y cells against high-dose corticosterone-induced injury. | Liping Chen Fawei Wang Miao Geng Hongyan Chen Dongmei Duan | 2011 | Neural Regeneration Research2011，6，21： | 2 |
| 2 | Researching the use of Wiki's to facilitate group work显示文摘 | Ramanau R Geng Fawei | 2009 | Procedia Social and Behavioral Sciences2009，1，1： | 1 |
| 3 | Shuyusan-containing serum protects SH-SY5Y cells against corticosterone-induced impairment显示文摘The Chinese herb Shuyusan,whose main constituent is jasminoidin,has been shown to protect SH-SY5Y cells against corticosterone-induced damage.SH-SY5Y cells injured by 400 μmol/L corticosterone were treated with 5 and 30 μg/mL Shuyusan-containing serum.Results revealed that Shuyusan-containing serum elevated the survival rate of SH-SY5Y cells,reduced Bax expression,increased Bcl-2 expression,markedly elevated brain-derived neurotrophic factor mRNA expression,and blocked cell apoptosis.Moreover,the effect of high-dose (30 μg/mL) Shuyusan-containing serum was more remarkable.Therefore,Shuyusan-containing serum appears to protect SH-SY5Y cells against corticosterone-induced impairment by adjusting the expression of apoptosis-associated proteins and brain-derived neurotrophic factor.Moreover,high-dose Shuyusan-containing serum has a protective effect on high-dose corticosterone-induced impairment. | Liping Chen Zhigao Sun Fawei Wang Chengyong Xu Miao Geng Hongyan Chen Dongmei Duan | 2013 | Neural Regeneration Research2013，8，22： | 1 |
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