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    题名 作者 年代 出处 被引量
1Suitability and limitations of mesenchymal stem cells to elucidate human bone illness显示文摘Functional impairment of mesenchymal stem cells(MSCs),osteoblast progenitor cells,has been proposed to be a pathological mechanism contributing to bone disorders,such as osteoporosis(the most common bone disease)and other rare inherited skeletal dysplasias.Pathological bone loss can be caused not only by an enhanced bone resorption activity but also by hampered osteogenic differentiation of MSCs.The majority of the current treatment options counteract bone loss,and therefore bone fragility by blocking bone resorption.These socalled antiresorptive treatments,in spite of being effective at reducing fracture risk,cannot be administered for extended periods due to security concerns.Therefore,there is a real need to develop osteoanabolic therapies to promote bone formation.Human MSCs emerge as a suitable tool to study the etiology of bone disorders at the cellular level as well as to be used for cell therapy purposes for bone diseases.This review will focus on the most relevant findings using human MSCs as an in vitro cell model to unravel pathological bone mechanisms and the application and outcomes of human MSCs in cell therapy clinical trials for bone disease.Izaskun Mitxitorena Arantza Infante Blanca Gener Clara I Rodríguez 2019World Journal of Stem Cells2019,11,9:2
2Generalized teleportation protocol显示文摘GENERALIZED GORDON GUSTAVO R I(]OLIN 2006Physical Review A2006,73,04:1
3Methylcyclohexanetransformation over dealuminated HBEA samples: Mechanismsand active sites显示文摘Marques J P Gener I Lopes J M 2006Applied Catalysis A-General2006,301,1:1
4Infrared spectroscop- ic study of the acid properties of dealuminated BEA zeolites 显示文摘Marques J P Gener I Ayrault P 2003Microporous and Mesoporous Materials2003,60,:1
5Influence of the Si/AI ratio and crystal size on the acidity and activity of HBEA zeolitcs显示文摘SIMON-MASSERON A MARQUES J P LOPES J M RIBEIRO F R GENER I GUISNET M 2007AppI Catal A2007,316,1:1
6Mutations involved in Aicardi-Gouti6res syndrome implicate SAMHD1 as regulator of the innate immune response显示文摘Rice GI Bond J Asipu A Brunette R L Manfield I W Cart I M Fuller J C Jackson R M Lamb T Briggs TA Ali M Gornall H Couthard L R Aeby A Attard-Montalto S P Bertini E Bodemer C Brockmann K Brueton L A Corry P C Desguerre I Fazzi E Cazorla A G Gener B Hamel B C Heiberg A Hunter M van der Knaap M S Kumar R Lagae L Landrieu P G Lourenco C M Marom D McDer- mott M F van der Merwe W Orcesi S Prendiville J S Rasmussen M Shalev S A Soler D M Shinawi M Spiegel R Tan T Y Vanderver A Wakeling EL Wassmer E Whittaker E Lebon P Stetson D B Bonthron D T Crow Y J 2009Nature Genetics2009,41,:1
7Adsorptive removal of aromatic compounds present in wastewater by using dealuminatedFaujasite zeolite显示文摘Koubaissy B Joly G Batonneau- Gener I 2011Industrial & Engineering Chemistry Research2011,50,9:1
8Autism-specific copy number variants further implicate the phosphatidylinositol signaling pathway and the glutamatergic synapse in the etiology of the disorder显示文摘Cusco I Medrano A Gener B 0,,10:1
9n-Heptane cracking on dealuminated HBEA zeolites显示文摘MARQUES J P GENER I LOPES J M RAMOA RIBEIRO F GUISNET M 2005Catal Today2005,,:1
10Mutations involved in Aicardi-Goutieres syndrome implicate SAMHD1 as regulator of the innate immune response 显示文摘Rice GI Bond J Asipu A Brunette RL Manfield IW Carr IM Fuller JC Jackson RM Lamb T Briggs TA Ali M GomaU H Couthard LR Aeby A Attard-Montalto SP Bertini E Bodemer C Brockmann K Bmeton LA Corry PC Desguerre I Fazzi E Cazorla AG Gener B Hamel BCJ Heiberg A Hunter M van der Knaap MS Kumar R Lagae L Landrieu PG Lourenco CM Marom D McDermott MF van der Merwe W Orcesi S PrendiviUe JS Rasmussen M Shalev SA Soler DM Shinawi M Spiegel R Tan TY Vanderver A Wakeling EL Wassmer E Whittaker E Lebon P Stetson DB Bonthron DT Crow YJ 2009 2009Nat Genet2009,41,7:1
11Infrared spectroscopic study of the acid properties of dealuminated BEA zeolites显示文摘J.P Marques I Gener P Ayrault J.C Bordado J.M Lopes F Ram?a Ribeiro M Guisnet 2003Microporous and Mesoporous Materials2003,,1:1
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