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| 1 | Starch grain analysis reveals function of grinding stone tools at Shangzhai site, Beijing显示文摘Prehistoric groundstone tools including slabs (metate, mo-pan) and mullers (mano, mo-bang) are often considered to be tools that were used to process cereals in ancient China. Most archaeologists believe that groundstone tools are indicators of an agrarian economy. This study employed starch grain analysis to examine a slab and a muller excavated from the Shangzhai Site (7500-7000 cal a BP), Beijing. Identifiable starch grains recovered from the stone tools were classified into 9 genera and 12 species, most of which were from acorns and foxtail millets. Remains from the oak species Q. mongolicus, Q. acuttssima, and Q. dentate were identified as well as a few starch grains from broomcorn (Panicum miliaseum) and bean (Vigna sp.). Other starch grains were from unidentifiable roots and grasses. A variety of starch grains indicates that the grinding stone tools were used to process not only cereals, but also other seeds or roots that had to be ground or husked, thus bringing into question the aforementioned cereal hypothesis. Because the numbers of starch grains from nuts and millets were so large, both gathering and cultivation might have been important economic patterns before 7000 years ago in Beijing area. Moreover, the starch remains are derived from plants that indicate that the paleoclimate of Beijing was wetter and warmer than today’s. | YANG XiaoYan YU JinCheng Lü HouYuan CUI TianXing GUO JingNing GE QuanSheng | 2009 | Science China Earth Sciences2009，52，8： | 32 |
| 2 | OPTICAL PROPERTIES OF GeO_2 AND Ge NANOCRYSTALS显示文摘he co m pound m aterial of n m size particles Ge O2 Si O2 w as synthesied through hydrolysis of Si( O C2 H4) and Ge Cl4 . A heat treatm ent w as carried out for the sa m ples at 100 ~1200 ℃in air . Its optical property w as deter mined by U V Vis spectur m . We have found that theabsorption edge of spectru m shifted progressively to longer w avelengths . The quantu m size ef fect of nanocrystals appears because crystals gro w and energy of optical band gap reduces d ueto the influence of te m perature . By the analysis of X ray diffraction w e have observed theprocess in w hich the structure of particles changed fro m disorder into order . | Y.H.Zhou 1) ,Y.Y.Feng 2) and H.Y.Lu 2) 1)Department of Physics Nanjing Normal University, Nanjing 210097,China 2)Physics and Ch寁O P T I C A L P R O P E R T I E S O F Ge O2 A N D Ge N A N O C R Y S T A L S Y. H. Zhou1) , Y. Y. Feng2) | 1999 | Acta Metallurgica Sinica(English Letters)1999，12，5： | 22 |
| 3 | Relationship among soluble CD105, hypersensitive C-reactive protein and coronary plaque morphology: an intravascular ultrasound study显示文摘背景:有随后的血栓形成的不稳定的匾的破裂是急性冠的症候群(交流) 的普通 pathophysiological 底层。探索预言匾特征的血索引具有潜在的意义。我们在可溶的 CD105,过分敏感的 C 反应的蛋白质(hs-CRP ) ,和冠的匾形态学之中调查了关系。方法:到 2006 年 12 月的从 2004 年 4 月的临床的研究在被划分成 3 个组的 130 个病人被进行:在稳定的咽峡炎(SA ) 的 56 个病人(43.1%) 组织,在不稳定的咽峡炎(UA ) 的 52 个病人(40.0%) 组织,在尖锐心肌的梗塞的 22 个病人(16.9%) 组织。可溶的 CD105 和 hs-CRP 的集中被 cardioangiography (CAG ) 病人在所有测量。动脉的血的血浆样品在过程以前被收集。可溶的 CD105 和 hs-CRP 的层次被连接酶的免疫吸着剂试金(ELISA ) 测量。结果:不稳定、破裂的匾与尖锐心肌的梗塞和 UA 在病人更经常被发现。代表性的区域(EEM CSA ) ,匾区域,类脂化合物水池区域和匾麻烦的外部有弹性的膜是显著地更大的在破裂并且不稳定的匾组。积极改变的、更薄的织物帽子,代表性的区域(MLA ) ,解剖和血栓是的更小的最小的腔显著地在更经常破裂并且不稳定的匾组。改变索引(RI ) 断然在 UA 组与可溶的 CD105 的层次被相关(r = 0.628, P <
0.01 ) 并且尖锐心肌的梗塞组(r = 0.639, P <
0.01 ) 。可溶的 CD105 和 hs-CRP 的层次在破裂的匾组是更高的。可溶的 CD105 >
4.3 ng/ml 被用来与操作 0.77 的特征(巨鸟)曲线区域的接收装置预言破裂的匾(95%信心间隔( CI ),66.8%-87.2%),72.8%的敏感,78.0%的特性和70.2%的精确性( P <
0.01 ),同样,为 hs-CRP >
,有一只巨鸟的 5.0 mg/ml 弄弯 0.70 的区域(95% CI ,59.2%-80.2%),70.2%的敏感,76.2%的特性和67.2%的精确性( P <
0.01 )。结论:匾特征与临床的演讲相关。可溶的 CD105 和 hs-CRP 的举起与匾不稳定性和破裂有关。 | CUI Song Lü Shu-zheng CHEN Yun-dai HE Guo-xiang MENG Li-jun LIU Jian-ping SONG Zhi-yuan LIU Xian-liang SONG Xian-tao GE Chang-jiang LIU Hong | 2008 | Chinese Medical Journal2008，，2： | 9 |
| 4 | Characterization of a critical role for CFTR chloride channels in cardioprotection against ischemia/ reperfusion injury显示文摘目的: 进一步描绘膀胱的纤维变性 transmembrane 传导力管理者(CFTR ) 的功能的角色在早、迟了(第二扇窗户) ischemic preconditioning (欧洲电脑生产厂商)- 并且 postconditioning (停靠港) 调停了对 ischemia/reperfusion (I/R ) 的 cardioprotection 损害。 | Sunny Yang XIANG Linda L YE Li-lu Marie DUAN Li-hui LIU Zhi-dong GE John A AUCHAMPACH Garrett J GROSS Dayue Darrel DUAN | 2011 | Acta Pharmacologica Sinica2011，32，6： | 9 |
| 5 | Early experiences on living donor liver transplantation in China: multicenter report显示文摘Background Because of the lack of brain death laws in China, the proportion of cadaveric organ donation is low. Many patients with end-stage liver disease die waiting for a suitable donor. Living donor liver transplantation (LDLT) would reduce the current discrepancy between the number of patients on the transplant waiting list and the number of available organ donors. We describe the early experience of LDLT in the mainland of China based on data from five liver transplant centers. Methods Between January 2001 and October 2003, 45 patients with end-stage liver disease received LDLT at five centers in China. The indication and timing, surgical techniques and complications, nonsurgical issues including rejection, infection, and advantages of LDLT in the series were reviewed. Actuarial patient and graft survival rates were calculated by using the Kaplan-Meier product-limit estimate. Statistical analysis was completed by using SPSS 10.0. Results All LDLT recipients were cirrhotic patients, except for one man with fulminant hepatic failure. Among the 45 cases of LDLT, 35 (77.8%) were performed in one center (the First Affiliated Hospital of Nanjing Medical University). The overall 1 and 3 year survival rate of the recipients was 93.1% and 92.0%, respectively. Of the 45 LDLT donors, there were 3 cases of biliary leakage, 2 subphrenic collections, 1 fat liquefaction around the incision and 1 biliary peritonitis after T tube removal. All donors recovered completely. Conclusions LDLT provides an excellent approach to addressing the problem of donor shortage in China even though the operation is complicated, uncompromising and difficult with respect to the safety of the donors and receptors. Despite early technical hurdles having been overcome, perfection of technique is still necessarily. At present, LDLT is a good choice for the patients with irreversible liver disease. | WANG Xue-hao YAN Lü-nan ZHANG Feng LI Xiang-cheng ZHU Ji-ye PENG Zhi-hai LIU Jin-hui LI Guo-qiang CHENG Feng SUN Bei-cheng GE Wen-gang | 2006 | Chinese Medical Journal2006，，12： | 7 |
| 6 | Purified human bone marrow multipotent mesenchymal stem cells regenerate infarcted myocardium in experimental rats显示文摘 | Zhang S Jia Z Ge J Gong L Ma Y Li T Guo J Chen P Hu Q Zhang P Liu Y Li Z Ma K Li L Zhou C | 2006 | 中国生物学文摘2006，20，5： | 5 |
| 7 | Effects of thiamine on Trichothecium and Alternaria rots of muskmelon fruit and the possible mechanisms involved显示文摘The effects of thiamine against pink and black spot rots caused by Trichothecium roseum and Alternaria alternata and modulation on the metabolism of reactive oxygen species(ROS)and phenylpropanoid pathway were investigated in this paper.In vitro test indicated that thiamine significantly inhibited mycelia growth and spore germination of T.roseum and A.alternata.Thiamine at 100 mmol L^(–1) effectively inhibited lesion development of muskmelon fruit inoculated with T.roseum or A.alternata,enhanced production rate of O_2^(-.)and H_2O_2 content,activities of catalase(CAT),ascorbate peroxidase(APX)and glutathione reductase(GR)in muskmelon fruit.Thiamine also affect phenylpropanoid pathway in muskmelon fruit by increasing the activities of phenylalanine ammonia lyase(PAL)and peroxidase(POD),the content of total phenolic compounds,flavonoids and lignin.These results suggest that the effects of thiamine on pink and black spot rots in muskmelon fruits are associated with its direct fungitoxic against the pathogens and the modulation of O_2^(-.)and H_2O_2 production,eliminating enzymes and phenylpropanoid pathway. | GE Yong-hong LI Can-ying Lü Jing-yi ZHU Dan-shi | 2017 | Journal of Integrative Agriculture2017，16，11： | 4 |
| 8 | A novel real-time RT-PCR with TaqM an-MGB probes and its application in detecting BVDV infections in dairy farms显示文摘A real-time RT-PCR assay using Taq Man-MGB probes was developed to detect and type the bovine viral diarrhea virus(BVDV) in cattle.Universal primers and Taq Man-MGB probes were designed from the 5′-untranslated region of known pestiviral sequences.Prior to optimizing the assay, c RNAs were transcribed in vitro from the BVDV 1 and BVDV 2 RTPCR products to make standard curves.The detection limit of the assay was 1.72×102 copies for BVDV 1 and 2.14×102copies for BVDV 2.The specificity of the assay evaluated on several BVDV strains including bovine herpesvirus 1(BHV 1), foot and mouth disease virus(FMDV) and several classical swine fever virus(CSFV) strains showed specific detection of the positive virus over 40 cycles.The assay was highly reproducible with the coefficient of variance ranging from 1.04 to 1.33% for BVDV 1 and from 0.83 to 1.48% for BVDV 2, respectively.Using this method, we tested a total of 2 327 cattle from three dairy farms for the presence of BVDV persistently infected(PI) animals.In this assay, each RT-PCR template contained a mixture of ten samples from different animals.The occurrence rate of PI cattle in three farms ranging from 0.9 to 2.54% could represent partly the PI rates in cattle farm in China.In conclusion, using our real-time PCR assay, we could effectively detect and type BVDV and identify PI cattle in a rapid and cost-effective manner. | ZHANG Yong-qiang LIU Hai-sheng WU Xiao-dong WANG Xiao-zhen LI Jin-ming ZHAO Yong-gang Lü Yan REN Wei-jie GE Sheng-qiang WANG Zhi-liang | 2015 | Journal of Integrative Agriculture2015，14，8： | 3 |
| 9 | Non-junctional Cx32 mediates anti-apoptotic and pro-tumor effects via epidermal growth factor receptor in human cervical cancer cells显示文摘OBJECTIVE To investigate the role of connexin proteins(Cx),which form gap junctions(GJ),in progression and chemotherapeutic sensitivity of cervical cancer(CaC x).METHODS We analyze the expression of Cx26,Cx30,Cx32 and Cx43 in human specimens consisting of:Normal cervix(n=78),CaCx FIGO stageⅠ(n=148),CaCx FIGO stageⅡ(n=165).In CaCx cell lines,Hela-Cx32(induced expression by doxycycline),C-33A(endogenously express Cx32)and si Ha(transiently transfected plasmid with Cx32),we detected the role of Cx32 against tostreptonigrin/cisplatin-induced apopotosisin presence or absence of functional GJ through using GJ inhibitors or low density cultural.Furtherly,we observed the relativity of Cx32 and EGFR expression in human specimens.Also,we detected the role of EGFR signaling pathway in the process of Cx32 anti-apoptosis through suppressed EGFR expression by inhibitors or si RNA sequences in cell lines.RESULTS We firstly demonstrated the expression of Cx32 was highly upregulated and accumulated in cytoplasm in the CaCx specimens,and the degree of upregulation correlated with advanced FIGO stages.Thus,in three human cervical cell lines,Cx32 was shown to suppress apoptosis when GJ formation is inhibited.No matter in cases of CaCx or cell lines,Cx32 expression was highly correlated with expression of EGFR and the EGFR pathway is an essential component of the Cx32-induced anti-apoptotic effect.CONCLUSION Cx32,traditionally tumor suppressive protein,was shown to be tumor protective against chemotherapy through EGFR pathway in a GJ-independent way. | Yi-fan ZHAO Yong-chang LAI Hui GE Yun-quan GUO Xue FENG Jia SONG Qin WANG Li-xia FAN Andrew L HARRIS Xi-yan WANG Liang TAO | 2017 | 中国药理学与毒理学杂志2017，31，10： | 3 |
| 10 | Association of telomere length with authentic pluripotency of ES/iPS cells显示文摘Telomerase 和 telomeres 为干细胞的不定的复制是重要的。最近,体的房间的 telomeres 被发现是 reprogrammed 在导致的 pluripotent 干细胞(iPSCs ) 伸长。然而,在在胚胎的干细胞(转换字符) 或 iPSCs 的 vivo 的发展 pluripotency 的 telomeres 的角色直接没被探讨。我们证明有长 telomeres 的转换字符展出真发展 pluripotency,由完全的转换字符小狗以及 germline 能干的怪物的产生证实了在啮齿类动物可得到的最紧的测试。有短 telomeres 的转换字符显示出减少的 teratoma 形成和怪物生产,并且没能产生完全的转换字符小狗。Telomere 长度高度被相关(r > 0.8 ) 与转换字符的发展 pluripotency。短 telomeres 减少 proliferative 率或转换字符的能力,改变与 telomere epigenetics 有关的基因的表示,为 embryogenesis 重要的下面调整基因并且破坏细菌房间区别。而且,有更长的 telomeres 的 iPSCs 与短 telomeres 比那些与更高的效率产生怪物。我们功能的 telomeres 为 ESCs/iPSCs 的发展 pluripotency 是必要的并且建议那 telomere 长度可以提供一个珍贵标记评估干细胞 pluripotency 的数据表演,特别地当紧测试不是可行的时。 | Junjiu Huang Fang Wang Maja Okuka Na Liu Guangzhen Ji Xiaoying Ye Bingfeng Zuo Minshu Li Ping Liang William W Ge John CM Tsibris David L Keefe Lin Liu | 2011 | Cell Research2011，21，5： | 3 |
| 11 | APOPTOSIS AND TAXOL PRODUCTION IN SUSPENSION CULTURES OF Taxus spp.CELLS显示文摘The hallmark of apoptosis, in suspension cultures of Taxus spp. cells induced by fungal extractive or by abiotic means, was studied by total DNA agarose gel electrophoresis and in situ end-labeling. The cleavage of nuclear DNA (nDNA) into oligonucleosomal fragments(DNA laddering) was a characteristic of apoptosis, which involved cell shrinkage, condensation of cytoplasm and tracheary elements differentiation. Terminal deoxynucleotidy transferase-mediated dUTP nick end in situ labeling (TUNEL) assay of Taxus spp. cells showed that fungal extractive or abiotic elicltors (Ce4+, Taxol, H2O2) induced TUNEL positive. Also, the increase of the apoptotic cell ratio was accompanied by the increase of secondary metabolites (especially Taxol). These results suggest that apoptosis may have some coincidence with biosynthesis of Taxol. The implication of apoptosis for the production of secondary metabolites in plant cell cultures is discussed. | Yuan Y. J., Ma L Y., Ge Z. Q.,and Miao Z. Q. Zeng A.P. (Department of biochemical engineering, Tianjin University, Tianjin 300072, China) (Biochemical Engineering Division, GBF,D-38124 Breunschweig, Germany) | 2000 | 化工学报2000，51，S1： | 2 |
| 12 | Engrafted bone marrow-derived flk-(1+) mesenchymal stem cells regenerate skin tissue显示文摘 | Deng W Han Q Liao L Li C Ge W Zhao Z You S Deng H Murad F Zhao RC | 2006 | 中国生物学文摘2006，20，5： | 2 |
| 13 | Artificial synthesis of interspecific chimeras between tuber mustard (Brassica juncea ) and cabbage (Brassica oleracea) and cytological analysis 显示文摘 | Chen L P Ge Y M Zhu X Y | 2006 | Plant Cell Rep2006，25，： | 1 |
| 14 | Lens transglutaminase and cataract formation显示文摘 | Lorand L Hsu LK Siefring GE Jr | 1981 | Proc Natl Acad Sci USA1981，78，： | 1 |
| 15 | Tropospheric corrections to SAR interferometry from observations显示文摘 | Janssen V Ge L Rizos C | 2004 | GPS Solutions2004，，8： | 1 |
| 16 | HOLSR:a hierarchical proactive routing mechanism for mobile Ad Hoc networks显示文摘 | Gonzalez L V Ying Ge Lamont I | 2005 | IEEE Communications Magazine2005，，： | 1 |
| 17 | Experimental Study on the Characterization of Worn Surface Topography with CharacteristicRoughness Parameter显示文摘 | Zhu H Ge S R Huang X L | 2003 | Wear2003，255，16： | 1 |
| 18 | Effects of pH on the chlorination process of phenols in drinking water 显示文摘 | Ge F Zhu L Z Chen H R | 2006 | J Hazard Mater2006，133，13： | 1 |
| 19 | Temperature-Dependent Photoluminescence of ZnO Nanorods Prepared by a Simple Solution Route显示文摘 | Lv Y Z Zhang Y H Li C P Ren L R Guo L Xu H B Ding L Yang C L Ge W K and Yang S H | 2007 | Luminescence2007，，： | 1 |
| 20 | Dual-labeled glucose binding protein for ratiometric measurements of glucose显示文摘 | GE Xudong TOLOSA L RAO Govind | 2004 | Anal Chem2004，76，： | 1 |
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