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| 1 | Psychosocial mechanisms for the transmission of somatic symptoms from parents to children显示文摘AIM: To examine familial aggregation of irritable bowel syndrome(IBS) via parental reinforcement/modeling of symptoms, coping, psychological distress, and exposure to stress.METHODS:Mothers of children between the ages of8 and 15 years with and without IBS were identified through the Group Health Cooperative of Puget Sound.Mothers completed questionnaires,including the Child Behavior Checklist(child psychological distress),the Family Inventory of Life Events(family exposure to stress),SCL-90R(mother psychological distress),and the Pain Response Inventory(beliefs about pain).Children were interviewed separately from their parents and completed the Pain Beliefs Questionnaire(beliefs about pain),Pain Response Inventory(coping)and Child Symptom Checklist[gastrointestinal(GI)symptoms].In addition,health care utilization data was obtained from the automated database of Group Health Cooperative.Mothers with IBS(n=207)and their 296 children were compared to 240 control mothers and their 335 children,while controlling for age and education.RESULTS:Hypothesis 1:reinforcement of expression of GI problems is only related to GI symptoms,but not others(cold symptoms)in children.There was no significant correlation between parental reinforcement of symptoms and child expression of GI or other symptoms.Hypothesis 2:modeling of GI symptomsis related to GI but not non-GI symptom reporting in children.Children of parents with IBS reported more non-GI(8.97 vs 6.70,P<0.01)as well as more GI(3.24 vs 2.27,P<0.01)symptoms.Total health care visits made by the mother correlated with visits made by the child(rho=0.35,P<0.001 for cases,rho=0.26,P<0.001 for controls).Hypothesis 3:children learn to share the methods of coping with illness that their mothers exhibit.Methods used by children to cope with stomachaches differed from methods used by their mothers.Only 2/16 scales showed weak but significant correlations(stoicism rho=0.13,P<0.05;acceptance rho=0.13,P<0.05).Hypothesis 4:mothers and children share psychological traits such as anxiety,depression,and somatization.Child psychological distress correlated with mother’s psychological distress(rho=0.41,P<0.001 for cases,rho=0.38,P<0.001 for controls).Hypothesis 5:stress that affects the whole family might explain the similarities between mothers and their children.Family exposure to stress was not a significant predictor of children’s symptom reports.Hypothesis 6:the intergenerational transmission of GI illness behavior may be due to multiple mechanisms.Regression analysis identified multiple independent predictors of the child’s GI complaints,which were similar to the predictors of the child’s non-GI symptoms(mother’s IBS status,child psychological symptoms,child catastrophizing,and child age).CONCLUSION:Multiple factors influence the reporting of children’s gastrointestinal and non-gastrointestinal symptoms.The clustering of illness within families is best understood using a model that incorporates all these factors. | Miranda AL van Tilburg Rona L Levy Lynn S Walker Michael Von Korff Lauren D Feld Michelle Garner Andrew D Feld William E Whitehead | 2015 | World Journal of Gastroenterology2015,21,18: | 2 |
| 2 | The place of eprints in scholarly information delivery显示文摘 | Garner J Horwood L Sullivan S | 2001 | Online Information Review2001,25,4: | 1 |
| 3 | Research Coordination Networks: Evidence of the Relationship Between Funded Interdisciplinary Networking and Scholarly Impact 显示文摘 | Porter A L Garner J Crowl T | 2012 | Bioscience2012,62,3: | 1 |
| 4 | Social competence among low-income preschoolers:emotion socialization practices and social cognitive correlates显示文摘 | GARNER P W J ONES D C MINER J L | 1994 | Child Development1994,65,2: | 1 |
| 5 | The effects of leukocyte reduction on matrix metalloproteinase release in cardiopulmonary bypass 显示文摘 | Garner JR Stroud RE Finklea L | 2004 | J Extra Corpor Technol2004,36,2: | 1 |
| 6 | Absolute Isotopic Abundance Ratio and the Atomic Weight of Chlorine 显示文摘 | Shields W R Murphy T J Garner E L | 1962 | Journal of the A- merican Chemical Society1962,84,: | 1 |
| 7 | A highly sensi- tive fluorescent sensor for palladium based on the allyl- ic oxidative insertion meehanism显示文摘 | SONG F GARNER A L KOIDE K | 2007 | Journal of the A merican Chemical Society2007,129,12: | 1 |
| 8 | Characteristics and capabilities of the hyperspectral imaging microscope显示文摘 | Schultz R A Garner H R | 2002 | IEEE Engineering in Medicine and Biology2002,21,4: | 1 |
| 9 | Absolute isotopic abundance ratio and the atomic weight of bromine显示文摘 | Catanzaro E J Murphy T J Garner E L | 1964 | Journal of Research of the National Institute of Standards and Technology1964,68,: | 1 |
| 10 | Oxidation state specific fluorescent method for palladium (II) and platinum (IV) based on the catalyzed aromatic Claisen rear- rangement显示文摘 | GARNER A L KOIDE K | 2008 | Journal of the American Chemical Socie ty2008,130,16: | 1 |
| 11 | Natural variations in the abundance ratio and the atomic weight of copper显示文摘 | Shield W R Goldich S S Garner E L | 1965 | J Geophys Res1965,70,: | 1 |
| 12 | Sex-Sorting mammalian sperm: concept to application in animals显示文摘 | Garner D L | 2001 | Androl2001,22,: | 1 |
| 13 | Enhancement of a catalysis-based fluorometrie detection method for pal- ladium through rational fine-tuning of the palladium species显示文摘 | GARNER A L SONG F KOIDE K | 2009 | Journal of the American Chemical Society2009,131,: | 1 |
| 14 | Nanosecond Electric Pulses Penetrate the Nucleus and Enhance Speckle Formation显示文摘 | Chen N Garner A L Chen G | 2007 | Biochem Biophys Res Commun2007,364,2: | 1 |
| 15 | Development of a shape memory alloy actuated biomimetie vehicle 显示文摘 | Garner L J Wilson L N Lagoudas D C | 2000 | Smart Materials and Structures2000,9,: | 1 |
| 16 | Circumstances of death in sudden death in epilepsy: interviews of bereaved xelatrces显示文摘 | Nashef L Garner S Sander J W A S | 1998 | J Neurol Neurosurg Psychialt1998,64,: | 1 |
| 17 | Interaction between CYP1 A1 polymorphic variants and dietary exposures influencing ovarian cancer risk 显示文摘 | Terry KL Titus-Emstoff L Garner EO | 2003 | Cancer Epidemiol Biomarkers Prev2003,12,: | 1 |
| 18 | Determination of unlabeled and ^13C6-labeled moricizine in hmuan plasma using thermospray liquid chmmatogramphy-mass spectrometry显示文摘 | PIENIASZEMK H J SHEN H L GARNER D M | 1989 | J Chromatogr1989,493,1: | 1 |
| 19 | Time course and variability of dark focus 显示文摘 | Baker R Brown B Garner L | 1983 | Invest Ophthalmol Vis Sci1983,24,: | 1 |
| 20 | The mechanical properties of 316L/304L stainless steels, Alloy 718 and Mod 9Cr-1Mo after irradiation in a spallation environment 显示文摘 | Maloy S A James M R Willcutt G Sommer W F Sokolov M Snead L L Hamilton M L Garner F | 2001 | Journal of Nuclear Material2001,296,: | 1 |