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90篇 您的检索式:作者名="Garbisa"
    题名 作者 年代 出处 被引量
1Tetrahydrocurcumin inhibits HT1080 cell migration and invasion via downregulation of MMPs and uPA显示文摘瞄准:Tetrahydrocurcumin (THC ) 是杂种狗枯茗的活跃代谢物。举办类似的药理学活动到杂种狗枯茗被报导了。参予细胞外的矩阵(ECM ) 的朊酶降级涉及癌症房间转移。现在的学习调查杂种狗枯茗的最终的代谢物的效果, THC,在侵略和高度变形的 HT1080 人的纤维肉瘤房间的警句ü i ty 上。方法:HT1080 房间侵略和移植上的 THC 的效果用 Boyden 房间试金被决定。房间粘附试金被用于检验房间的绑定到 ECM 分子。Zymography 试金被用来在矩阵 metalloproteinase (MMP ) 上分析 THC 的效果 -2, MMP-9,和尿激 plasminogen 使活跃之物(在 A 上面) 从 HT1080 房间的分泌物。metalloproteinase (TIMP ) 的织物禁止者 -2 和膜类型 1 个矩阵 metalloproteinase (MT1-MMP ) 蛋白质层次被西方的弄污分析。结果:有 THC 的治疗以一种剂量依赖者方式减少了 HT1080 房间侵略和移植。THC 也减少了对 Matrigel 和 laminin 涂的盘子的房间粘附。由 zymography 的分析证明有 THC 的处理减少了 MMP-2 的层次, MMP-9,并且在 A 上面。THC 也禁止了西方的污点分析检测的 MT1-MMP 和 TIMP-2 蛋白质的层次。结论:我们的调查结果表明 THC 减少了 HT1080 房间侵略和移植。癌症房间侵略的抑制与被联系下面 ECM 降级酶的规定和对 ECM 蛋白质的房间粘附的抑制。Supachai YODKEEREE Spiridione GARBISA Pornngarm LIMTRAKUL 2008Acta Pharmacologica Sinica2008,29,7:2
2Basement membrance collagen requirements for attachment and growth of mammary epithelium 显示文摘Wicha M S Liotta L A Garbisa S 1979Exp Cell Res1979,124,:1
3Metastatic potentialcorrelates with enzymatic degradation of basement membrane colla-gen显示文摘Liotta L A Tryggvason K Garbisa S 1980Nature1980,28,4:1
4Matrix Metalloproteinase -2 Protein in Lung Periphery is related to COPD Progression 显示文摘Baraldo S Bazzan E Zanin M E Turato G Garbisa S Maestrelli P Papi A Miniati M Fabbri L M Zuin R Saetta M 2007Chest2007,132,6:1
5Preliminary evaluation of inhibition of matrix-metalloprotease MMP-2 and MMP-9 by Passiflora edulis and P. foetida aqueous extracts显示文摘L. Puricelli I. Dell’Aica L. Sartor S. Garbisa R. Caniato 2003Fitoterapia2003,,3:1
6Metastatic potential correlates with enzymatic degradation of basement membrane collagen 显示文摘Liotta LA Tryggvason K Garbisa S 1980Nature1980,284,5751:1
7Metastatic potential correlates with enzymatic degradation of basement membrane collagen显示文摘Liotta LA Tryggvason K Garbisa S 1980Nature1980,284,5751:1
8(-)Epigallocatechin-3-gallate inhibits leukocyte elastase:potential of the phyto-factor in hinde-ring inflammation,emphysema,and invasion显示文摘Sartor L Pezzato E Garbisa S 2002J Leukocgto Biol2002,71,1:1
9Metastatic potential correlates with enzymatic degradation of basement member collagen显示文摘LIOTTA LA TRGGVASON K GARBISA S 1980Nature1980,284,5751:1
10Tumor invasion:molecular shears blunted by green tea显示文摘GARBISA S BIGGIN S CAVALLARIN N 1999Nature Medicine1999,5,:1
11Tumor gelatinases and invasion inhibited by the green tea flavanol epigallocatechin-3-gallate显示文摘Garbisa S Sartor L Biggin S 0,,04:1
12Noncontiguous unstable spine fracture显示文摘Wiltenberg RH Garbisa S 2002Spine2002,27,3:1
13Metastatic potential correlates with enzymatic degradation of basement membrane collagen显示文摘Liotta LA Tryggvason K Garbisa S 1980Nature1980,284,:1
14The use of reversephase higher performance liquidchromatography and precolumn derivatization with dansyl chloride for quantitation of specific amino acids in collagen and e- lastin显示文摘Negro A Garbisa S Gotte L 1987Anal Chem1987,160,:1
154-Alkyliden-β-lactams conjugated to polyphenols: Synthesis and inhibitory activity显示文摘Gianfranco Cainelli Paola Galletti Spiridione Garbisa Daria Giacomini Luigi Sartor Arianna Quintavalla 2005Bioorganic & Medicinal Chemistry2005,,22:1
16Effect of glucose and heparin on mesangial alpha 1(Ⅳ)COLL and MMP-2/TIMP-2 mRNA expression显示文摘Caenazzo C Garbisa S Onisto M 1997Nephrol Dial Transplant1997,12,3:1
17Matrix metalloproteinases and their role in the renal epithelial mesenchymal transition显示文摘ARESU L BENALI S GARBISA S 2011Histol Histopathol2011,26,3:1
184-Alkylidene-azetidin-2-ones: novel inhibitors of leukocyte elastase and gelatinase显示文摘Gianfranco Cainelli Paola Galletti Spiridione Garbisa Daria Giacomini Luigi Sartor Arianna Quintavalla 2003Bioorganic & Medicinal Chemistry2003,,24:1
19Metastatic potential correlates with enzymatic degradation of bacement membrane collagen显示文摘Liottal A Tryggvason K Garbisa S 1980Nature1980,284,1:1
20Noncontiguous unstable spine fracture显示文摘Wiltenberg RH Garbisa S Steffen R 2002Spine2002,3,:1
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