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| 1 | Artemisinin mimics calorie restriction to extend yeast lifespan via a dual-phase mode: a conclusion drawn from global transcriptome profiling显示文摘Calorie restriction(CR) promotes longevity among distinct organisms from yeast to mammals. Although CR-prolonged lifespan is believed to associate with enhanced respiratory activity, it is apparently controversial for accelerated energy consumption regardless of insufficient nutrient intake. In reconciling the contradiction of less food supply versus much metabolite dispense, we revealed a CR-based mode of dual-phase responses that encompass a phase of mitochondrial enhancement(ME) and a phase of post-mitochondrial enhancement(PME), which can be distinguished by the expression patterns and activity dynamics of mitochondrial signatures. ME is characterized by global antioxidative activation, and PME is denoted by systemic metabolic modulation. CR-mediated aging-delaying effects are replicated by artesunate, a semi-synthetic derivative of the antimalarial artemisinin that can alkylate heme-containing proteins, suggesting artesunate-heme conjugation functionally resembles nitric oxide-heme interaction. A correlation of artesunate-heme conjugation with cytochrome c oxidase activation has been established from adduct formation and activity alteration. Exogenous hydrogen peroxide also mimics CR to trigger antioxidant responses, affect signaling cascades, and alter respiratory rhythms, implying hydrogen peroxide is engaged in lifespan extension. Conclusively, artesunate mimics CR-triggered nitric oxide and hydrogen peroxide to induce antioxidative networks for scavenging reactive oxygen species and mitigating oxidative stress, thereby directing metabolic conversion from anabolism to catabolism, maintaining essential metabolic functionality, and extending life expectancy in yeast. | WANG DaTing WU Ming LI SiMing GAO Qian ZENG QingPing | 2015 | Science China(Life Sciences)2015，58，5： | 6 |
| 2 | Study on Commercial Application of FP-DSN Sulfur Transfer Additive in FCC Unit显示文摘The FCC unit with addition of various inventories of the FP-DSN type sulfur transfer additive was tested in a commercial scale. The effect of the sulfur transfer additive was analyzed by investigating the indicators related with the regenerator flue gas composition,the dry gas composition before desulfurization,the LPG composition before desulfurization,the acid gas,and the yield of gasoline and diesel. The test results indicated that the sulfur was trans ferred from the feed stream into the dry gas,LPG and acid gas,and the sulfur transfer effect was obvious only when the inventory of sulfur transfer additive exceeded over 2.0% of total FCC catalyst inventory. | Gao Siming Han Rongxian Chen Desheng(SINOPEC Qingdao Petrochemical Company,Qingdao 266043) | 2009 | China Petroleum Processing & Petrochemical Technology2009，11，2： | 2 |
| 3 | Construction of Lactuca sativa Plastid Transformation Vector and High-level Expression of gfp Gene in Escherichia coli显示文摘Using genomic DNA of bolting-tolerant lettuce as a template,flanking fragments of lettuce plastid rpo A gene were amplified and cloned by PCR. Targeting the sites of these two fragments,homologous recombinant fragments of exogenous gene were integrated to construct lettuce plastid expression vector p Brpo AGFP,which harbored the expression cassette Prrn-gfp-aad A-Tpsb A. The results showed that the amplified flanking fragments were 1.2 and 1.1 kb in size. After sequencing,restriction digestion,ligation and transformation,lettuce plastid expression vector containing expression cassette Prrn-gfp-aad A-Tpsb A was constructed and confirmed by SDS-PAGE electrophoresis. The results of SDS-PAGE electrophoresis indicated that gfp gene was efficiently expressed under the regulation of plasmid specific promoter Prrn and terminator Tpsb A. GFP accounted for 45. 6% of total soluble proteins; inclusion bodies accounted for 47.5 % of bacterial proteins,which reached relatively high expression levels. The construction of lettuce plastid expression vector p Brpo A-GFP laid a solid foundation for establishment of subsequent lettuce plastid transformation system and genetic improvement of lettuce using various functional genes. | Siming HOU Liying ZHOU Lulu BU Chunlei YANG Ting GAO Tian TIAN Zheng'an YANG | 2016 | Agricultural Biotechnology2016，5，4： | 0 |
| 4 | Novel self-assembled porous yolk-shell NiO nanospheres with excellent electrochromic performance for smart windows显示文摘With the rapid development of optoelectronics,electrochromic(EC)materials(ECMs)with the advan-tages of low power consumption,easy viewing,high contrast ratio,etc have attached more and more attention from the fields of smart windows,electronic billboards,emerging wearable and portable electronics,and other next-generation displays.Nickel oxide(NiO)is a promising candidate for high-performance ECMs because of its neutral-colored states and low cost.However,NiO-based ECMs still face the problem of slow switching speed due to their low electrical conductivity and small lattice spacing.Metal-organic frameworks(MOFs)are promising candidates to fabricate hollow and porous transition metal oxides(TMOs)with high ion transport efficiency,excellent specific capacitance,and electrochemical activities.In this work,porous yolk-shell NiO nanospheres(PYS-NiO NSs)were syn-thesized via a solvothermal and subsequent calcination process of Ni-MOF,which exhibited outstanding EC performance.Because the large specific surface areas and hollow porous nanostructures were conducive to ionic transport,PYS-NiO NSs exhibited a fast coloring/bleaching speed(3.6/3.9 s per one coloring/bleaching cycle)and excellent cycling stability(82%of capacity retention after 3000 cycles).These superior EC properties indicated that the PYS-NiO NSs was a promising candidate for high-performance EC devices.This work provides a new and feasible strategy for the efficient preparation of TMOs ECMs with good EC performance,especially fast switching speed. | Baoshun Wang Ya Huang Siming Zhao Run Li Di Gao Hairong Jiang Rufan Zhang | 2024 | Particuology2024，84，1： | 0 |
| 5 | Selection and evaluation of suitable tree species in dry and dusty mining areas of Northwest China显示文摘To select drought-resistant and dust-tolerant native species suitable for use in the rehabilitation of major coal bases in northwest China,nine tree species were identified for growth rates,biomass,harm index,and physiological indices under drought and high dust stress conditions.The results showed that,in the dust resistance index system,the order was Caragana korshinskii>Amorpha fruticosa>Sabina vulgaris>Hedysarum scoparium>Tamarix chinensis>Ammopiptanthus mongolicus>Ulmus pumila>C aryopteris mongholica>Elaeagnus angustifolia.In a comprehensive drought and dust resistance index system,14 indices(such as shoot length,stomatal conductance,and peroxidase)had the larger weight indices.The drought and dust resistance order of the tree species was C aragana korshinskii>Ulmus pumila>Amorpha fruticosa>Sabina vulgaris>Caryopteris mongholica>Ammopiptanthus mongolicus>H edysarum scoparium>Tamarix chinensis>Elaeagnus angustifolia.This study provides effective strategies and references for selecting suitable tree species for arid mining sites in China,and also for the revegetation of coal mining sites worldwide. | Xiaofang Zhu Bing Cao Siming Zhao Xing Wang Hao Zhang Deping Gao Yongfeng Duan | 2022 | Journal of Forestry Research2022，33，6： | 0 |
| 6 | Cloning and Sequence Analysis of Polygalacturonase(PG) Promoter in Tomato显示文摘In this study,1 500 bp PG gene promoter was amplified from leaves of tomato cultivar‘Zhongshu No.4'.The bioinformatic analysis of PG promoter sequences was conducted.PG promoter elements were predicted and analyzed by PLANTCARE and PLACE.The results showed that tomato PG promoter contained multiple cis-acting regulatory elements such as typical basic elements TATA-Box and CAAT-Box,light responsive elements 3-AF1 binding site,AT1-motif,ATCTmotif,Box 4,Box I,GA-motif,GT1-motif,Sp1 and MRE,heat stress-responsive element HSE,ethylene-responsive element ERE,meristem-specific regulatory element CCGTCC-box,endosperm expression-related regulatory elements GCN4_motif and Skn-1_motif,defense and stress responsiveness element TC-rich repeats,and circadian control-related element circadian,indicating that the expression of tomato PG gene is related to light,temperature,hormone,stress and other factors.This study laid the foundation for subsequent research about regulation of PG gene expression in plants. | Siming HOU Liying ZHOU Lulu BU Chunlei YANG Ting GAO Tian TIAN Zheng'an YANG | 2016 | Agricultural Biotechnology2016，5，2： | 0 |
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