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| 1 | Trimming of a migrated metal stent for malignant colonic stricture using argon plasma coagulation显示文摘We report the first case of trimming of a migrated metal colonic stent for stent induced severe anorectal pain. We present a case of a 54-year-old female with history of metastatic colorectal carcinoma who had stent placement secondary to obstruction. Subsequent distal migration of the stent caused ulcerations into the rectal mucosa and excruciating anorectal pain. We used argon plasma coagulation (APC) to successfully trim the exposed distal portion of the metal stent and rat tooth forceps to retrieve the stent fragments. The use of APC for trimming metallic stents is an effective procedure that can be used to trim migrated rectal stents that result in significant rectal pain. To date, few studies have been published that use APC to trim metallic stents placed in the gastrointestinal tract. To the best of our knowledge, ours is the only known case in which the indication for stent trimming was severe stent induced rectal pain. The procedure resulted in complete relief of patient symptoms. Therefore, APC is a safe and effective way to trim colo-rectal stents to definitively relieve the symptom of stent induced rectal pain in patients who have experienced distal stent migration and mucosal ulceration. | Kiran Venkat Rao Gagan Deep Beri Weizheng William Wang | 2010 | World Journal of Gastrointestinal Endoscopy2010，2，2： | 1 |
| 2 | Gold Nanoparticles Inhibit VEGF165-Induced Migration and Tube Formation of Endothelial Cells via the Akt Pathway显示文摘 | Yunlong Pan Qing Wu Li Qin Jiye Cai Bin Du Gagan Deep | 2014 | BioMed Research International2014，，： | 1 |
| 3 | Targeting Tumor Microenvironment with Silibinin: Promise and Potential for a Translational Cancer Chemopreventive Strategy显示文摘 | Gagan Deep Rajesh Agarwal | 2013 | Current Cancer Drug Targets2013，，5： | 1 |
| 4 | Exosomes secreted under hypoxia enhance invasiveness and stemness of prostate cancer cells by targeting adherens junction molecules显示文摘 | Anand Ramteke Harold Ting Chapla Agarwal Samiha Mateen Ranganathan Somasagara Anowar Hussain Michael Graner Barbara Frederick Rajesh Agarwal Gagan Deep | 2015 | Mol. Carcinog2015，，7： | 1 |
| 5 | Small particle reagent:a Saponin-based modification显示文摘 | Gagan Deep Singh Sodhi G S | 2007 | Journal of Forensic Identification2007，57，2： | 1 |
| 6 | Study of Dehydrocoupling Reactions of Diorganotin Dihydrides R^1R^2SnH2 with Biuret显示文摘不对称的 phenylmethyltin dihydride (PhMeSnH2 ) 的反应, phenylethyltin dihydride (PhEtSnH2 ) , phenylbutyltin dihydride (PhBuSnH2 ) 和有 biuret (H2L ) 的 butylmethyltin dihydride (BuMeSnH2 ) 经由 SnH/NH dehydrocoupling 继续负担得起相应 tetra 坐标周期的产品。在 1:1, 2:1 和 1:2 的臼齿的比率的反应被学习了。那么孤立的黄衍生物在极的溶剂是可溶的并且在 nonpolar 溶剂不可溶解。当 2:1 和 1:2 没去结束时, 1:1 反应去了结束,这被发现当 2:1 和 1:2 没去结束时。衍生物被元素的分析和分光镜的技术 viz 描绘了。红外, 1H NMR, 13C NMR, 119Sn NMR。反应产品的 DSC 和 TGA 也被学习了。所有衍生物是热地稳定的 upto (190 極畮汣摩湩 ?眠獡甠敳 d ??鍼 吗?? | DEEP, Gagan NARULA, A.K. | 2007 | Chinese Journal of Chemistry2007，25，7： | 0 |
| 7 | Role of extracellular vesicles secretion in paclitaxel resistance of prostate cancer cells显示文摘Aim:The development of chemotherapy resistance is the major obstacle in the treatment of advanced prostate cancer(PCa).Extracellular vesicles(EVs)secretion plays a significant role among different mechanisms contributing to chemoresistance.Hence,inhibition of EVs release may increase the efficacy of chemotherapeutic drugs against PCa.Methods:Paclitaxel(PTX)resistant PCa cells(PC3-R and DU145-R)were treated with GW4869,a known exosome biogenesis inhibitor.EVs were isolated from the conditioned media by ExoQuick-based precipitation method and characterized for concentration and size distribution by nanoparticle tracking analysis.The effect of GW4869 treatment on the survival and growth of PCa cells was assessed by MTT,and colony formation assays in vitro,and ectopic PC3-R xenografts in male athymic nude mice in vivo.The effect of other EV biogenesis inhibitors,imipramine and dimethyl amiloride(DMA),treatment was also analyzed on the survival of PC3-R cells.Results:GW4869(10-20μM)treatment of PTX resistant PCa cells significantly reduced the release of small EVs(50-100 nm size range)while increasing the release of larger EVs(>150 nm in size),and inhibited their clonogenicity.Moreover,GW4869(5-20μM)treatment(24-72h)significantly inhibited the survival of PC3-R cells in a dose-dependent manner.We observed a similar growth inhibition with both imipramine(5-20μg/mL)and DMA(5-20μg/mL)treatment in PC3-R cells.Furthermore,GW4869 treatment(IP)in mice bearing PC3-R xenografts significantly reduced the tumor weight(65%reduction,P=0.017)compared to the vehicle-treated control mice without causing any noticeable toxicity.Conclusion:Inhibiting the release of EVs could sensitize the resistant PCa cells to chemotherapy. | Ashish Kumar Pawan Kumar Mitu Sharma Susy Kim Sangeeta Singh Steven J.Kridel Gagan Deep | 2022 | Cancer Drug Resistance2022，5，3： | 0 |
| 8 | Embracing the Future:AI and ML Transforming Urban Environments in Smart Cities显示文摘This research explores the increasing importance of Artificial Intelligence(AI)and Machine Learning(ML)with relation to smart cities.It discusses the AI and ML’s ability to revolutionize various aspects of urban environments,including infrastructure,governance,public safety,and sustainability.The research presents the definition and characteristics of smart cities,highlighting the key components and technologies driving initiatives for smart cities.The methodology employed in this study involved a comprehensive review of relevant literature,research papers,and reports on the subject of AI and ML in smart cities.Various sources were consulted to gather information on the integration of AI and ML technologies in various aspects of smart cities,including infrastructure optimization,public safety enhancement,and citizen services improvement.The findings suggest that AI and ML technologies enable data-driven decision-making,predictive analytics,and optimization in smart city development.They are vital to the development of transport infrastructure,optimizing energy distribution,improving public safety,streamlining governance,and transforming healthcare services.However,ethical and privacy considerations,as well as technical challenges,need to be solved to guarantee the ethical and responsible usage of AI and ML in smart cities.The study concludes by discussing the challenges and future directions of AI and ML in shaping urban environments,highlighting the importance of collaborative efforts and responsible implementation.The findings highlight the transformative potential of AI and ML in optimizing resource utilization,enhancing citizen services,and creating more sustainable and resilient smart cities.Future studies should concentrate on addressing technical limitations,creating robust policy frameworks,and fostering fairness,accountability,and openness in the use of AI and ML technologies in smart cities. | Gagan Deep Jyoti Verma | 2023 | Journal on Artificial Intelligence2023，5，1： | 0 |
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