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| 1 | 添加酸对仔猪生产性能的影响显示文摘控制仔猪肠道酸度的研究已取得较大进展,主要是研究日粮或饮水中添加酸的效果。研究证明,添加酸有以下效果: ①添加后可降低断奶前后痢疾的发病率,使死亡率降到正常的范围; | John Gadd 丁丽敏 | 1991 | 国外畜牧科技1991，18，2： | 4 |
| 2 | 用饲料法保持仔猪消化道的健康显示文摘本文介绍用营养学方法减少猪的消化障碍发生次数和程度的方法。仔猪在3周龄之内,分泌到胃内的盐酸量不多,因此胃内pH为5或大于5,由此而给仔猪造成两个问题:首先,要消化胃内的蛋白质,如消化乳蛋白,pH必须在4以下,消化大豆或鱼蛋白pH必须在2.3以下。其次,酸度是调节胃内微生物平衡的重要因素,胃内保持酸性,则适合有益的乳酸杆菌繁殖,抑制有害的大肠杆菌、梭状芽孢杆菌、沙门氏菌、葡萄球菌等的繁殖。所以胃内的酸度小,则蛋白质不能充分消化,有害的细菌就能栖居在小肠。为防止这种现象发生,采用以下几种增加仔猪胃内酸度的方法。 | 李成龙 赵增礼 John Gadd | 1990 | 国外畜牧学(猪与禽)1990，，6： | 3 |
| 3 | Macrophage secretory products induce an inflammatory phenotype in hepatocytes显示文摘AIM:To investigate the influence of macrophages on hepatocyte phenotype and function.METHODS:Macrophages were differentiated from THP-1 monocytes via phorbol myristate acetate stimulation and the effects of monocyte or macrophageconditioned medium on HepG2 mRNA and protein expression determined.The in vivo relevance of these findings was confirmed using liver biopsies from 147 patients with hepatitis C virus(HCV)infection.RESULTS:Conditioned media from macrophages,but not monocytes,induced a transient morphological change in hepatocytes associated with upregulation of vimentin(7.8±2.5-fold,P=0.045)and transforming growth factor(TGF)-β1(2.6±0.2-fold,P<0.001)and downregulation of epithelial cadherin(1.7±0.02-fold,P=0.017)mRNA expression.Microarray analysis revealed significant upregulation of lipocalin-2(17-fold,P <0.001)and pathways associated with inflammation,and substantial downregulation of pathways related to hepatocyte function.In patients with chronic HCV,realtime polymerase chain reaction and immunohistochemistry confirmed an increase in lipocalin-2 mRNA(F0 1.0 ±0.3,F1 2.2±0.2,F2 3.0±9.3,F3/4 4.0±0.8,P= 0.003)and protein expression(F1 1.0±0.5,F2 1.3± 0.4,F3/4 3.6±0.4,P=0.014)with increasing liver injury.High performance liquid chromatography-tandem mass spectrometry analysis identified elevated levels of matrix metalloproteinase(MMP)-9 in macrophageconditioned medium,and a chemical inhibitor of MMP-9 attenuated the change in morphology and mRNA expression of TGF-β1(2.9±0.2 vs 1.04±0.1,P<0.001) in macrophage-conditioned media treated HepG2 cells.In patients with chronic HCV infection,hepatic mRNA expression of CD163(F0 1.0±0.2,F1/2 2.8±0.3,F3/4 5.3±1.0,P=0.001)and MMP-9(F0 1.0±0.4,F1/2 2.8±0.3,F3/4 4.1±0.8,P=0.011)was significantly associated with increasing stage of fibrosis.CONCLUSION:Secreted macrophage products alter the phenotype and function of hepatocytes,with increased expression of inflammatory mediators,suggesting that hepatocytes actively participate in liver injury. | Michelle Melino Victoria L Gadd Gene V Walker Richard Skoien Helen D Barrie Dinesh Jothimani Leigh Horsfall Alun Jones Matthew J Sweet Gethin P Thomas Andrew D Clouston Julie R Jonsson Elizabeth E Powell | 2012 | World Journal of Gastroenterology2012，18，15： | 3 |
| 4 | 《现代养猪生产技术——告诉你猪场盈利的秘诀》显示文摘由[英]John Gadd著,周绪斌博士、张佳博士和潘雪男高级畜牧师主译,万建美博士等29位畜牧兽医领域优秀专业人士参与翻译的《现代养猪生产技术——告诉你猪场盈利的秘诀》已经由中国农业出版社于2015年6月正式出版。本书详细介绍请扫右上侧二维码:购书方式:(1)用手机扫描右下侧二维码:(2)邮局汇款:地址:上海市闵行区北翟路2901号,邮编:201106,收款人:《国外畜牧学—猪与禽》编辑部。(3)书价:原价198元/本,优惠价158.4元/本(含邮费,如需快递,每本另付23元)。 | John Gadd 周绪斌 张佳 潘雪男 万建美 | 2015 | 国外畜牧学(猪与禽)2015，0，8： | 2 |
| 5 | 《现代养猪生产技术——告诉你猪场盈利的秘诀》显示文摘由[英]John Gadd著,周绪斌博士、张佳博士和潘雪男高级畜牧师主译,万建美博士等29位畜牧兽医领域优秀专业人士参与翻译的《现代养猪生产技术——告诉你猪场盈利的秘诀》已经由中国农业出版社于2015年6月正式出版。本书详细介绍请扫右上侧二维码:购书方式:(1)用手机扫描右下侧二维码:(2)邮局汇款:地址:上海市闵行区北翟路2901号,邮编:201106,收款人:《国外畜牧学—猪与禽》编辑部。 | John Gadd 周绪斌 张佳 潘雪男 万建美 | 2015 | 国外畜牧学(猪与禽)2015，0，9： | 2 |
| 6 | Improving logistics outsourcing through increasing buyer–provider interaction显示文摘 | Lars-Erik Gadde Kajsa Hulthén | 2009 | Industrial Marketing Management2009，，6： | 2 |
| 7 | Antineutrophil cytoplasmic antibodies crescentic allograft glomerulonephritis after sofosbuvir therapy显示文摘Antineutrophil cytoplasmic antibodies(ANCA) are well known to be associated with several types of vasculitis, including pauci-immune crescentic glomerulonephritis, a form of rapid progressive glomerular nephritis(RPGN). ANCA vasculitis has also been reported after administration of propylthiouracil, hydralazine, cocaine(adulterated with levimasole), allopurinol, penicillamine and few other drugs. All previously reported cases of drug-associated ANCA glomerulonephritis were in native kidneys. Sofosbuvir is a new and effective drug for hepatitis C virus infection. Here, we report a case of ANCA vasculitis and RPGN following sofosbuvir administration in a kidney transplant recipient. It also represents the first case of drug-associated ANCA vasculitis in a transplanted kidney. Further drug monitoring is necessary to elucidate the degree of association and possible causal effect of sofosbuvir and perinuclear ANCA vasculitis. | Shilpa Gadde Belinda Lee Laura Kidd Rubin Zhang | 2016 | World Journal of Nephrology2016，5，6： | 2 |
| 8 | Minimally invasive spleen-preserving distal pancreatectomy: Does splenic vessel preservation have better postoperative outcomes? A systematic review and meta-analysis显示文摘BACKGROUND: Minimally invasive spleen-preserving distal pancreatectomy(SPDP) can be performed with either splenic vessel preservation(SVP) or resection [Warshaw procedure(WP)]. The aim of this study was to evaluate the postoperative clinical outcomes of patients undergoing both methods.DATA SOURCES: Database search of PubM ed, Embase, Scopus,Cochrane, and Google Scholar was performed(2000-2014); key bibliographies were reviewed. Qualified studies comparing patients undergoing SPDP with either SVP or WP, and assessing postoperative complications were included. Calculated pooled risk ratio(RR) with the corresponding 95% confidence interval(CI) by random effects methods were used in the meta-analyses. RESULTS: The search yielded 215 studies, of which only 14 observational studies met our selection criteria. The studies included 943 patients in total; 652(69%) underwent SVP and 291(31%) underwent WP. Overall, there was a lower incidence of splenic infarction(RR=0.17; 95% CI: 0.09-0.33; P<0.001),gastric varices(RR=0.16; 95% CI: 0.05-0.51; P=0.002), and intra/postoperative splenectomy(RR=0.20; 95% CI: 0.08-0.49; P<0.001) in the SVP group. There was no difference in incidence of pancreatic fistula(WP vs SVP, 23.6% vs 22.9%;P=0.37), length of hospital stay, operative time or blood loss. There was moderate cross-study heterogeneity.CONCLUSIONS: SVP is a safe, efficient and feasible technique that may be used to preserve the spleen. WP may be more suitable for large tumors close to the splenic hilum or those associated with splenomegaly. Randomized clinical trials are justified to examine the long-term benefits of SVP-SPDP. | Fady Elabbasy Rahul Gadde Mena M Hanna Danny Sleeman Alan Livingstone Danny Yakoub | 2015 | Hepatobiliary & Pancreatic Diseases International2015，14，4： | 2 |
| 9 | The changing role of middlemen — Strategic responses to distribution dynamics显示文摘 | Robert Olsson Lars-Erik Gadde Kajsa Hulthén | 2013 | Industrial Marketing Management2013，，： | 2 |
| 10 | Microorganisms and heavy metal toxicity 显示文摘 | Gadd G M Griffiths A J | 1978 | Microb Ecol1978，4，： | 1 |
| 11 | 显示文摘 | Gadd G M | 2009 | J Chem Technol Biot2009，84，1： | 1 |
| 12 | TRIZ for engineers : enabling inventive problem solving显示文摘 | Gadd K | 2011 | Wiley2011，，： | 1 |
| 13 | Strain and medium-related variability in the yeast-mycelial transition of Aureobasidium pullulans显示文摘 | Gadd G M Cooper L A | 1984 | FEMS Microbiology Letters1984，23，1： | 1 |
| 14 | Bioremedial Potential of Microbial Mechanisms of Mmetal Mobilization and Immobilization显示文摘 | Gadd GM | 2000 | Curt Opin Biotechnol2000，11，3： | 1 |
| 15 | Surgical management of phyllodes tumors 显示文摘 | Mangi AA Smith BL Gadd MA | 1999 | Arch Surg1999，134，5： | 1 |
| 16 | Interaction of fungi with toxic metals显示文摘 | 1993 | 1993 | New Phytol1993，124，： | 1 |
| 17 | The chang role of purchasing:eeconsidering three strategic issues显示文摘 | GADDE L E HAKANSSON H H | 1994 | European Journal of Purchasing & Supply Management1994，，1： | 1 |
| 18 | Estimates of sand transport on the New York shelf using near-bottom current meter observations显示文摘 | Gadd P E Lavelle J W Swift D J P | 1978 | Journal of Sedimentary Petrology1978，48，1： | 1 |
| 19 | Surgical management of phyllodes tumors显示文摘 | Man AA Smith BL Gadd MA | 1999 | Arch surg1999，134，： | 1 |
| 20 | The relationship between cadmium uptake, potassium release and viability in Saccharomyces cerevisiae 显示文摘 | GADD GM MOWLL JL | 1983 | _Microbiology Letters1983，16，： | 1 |
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