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8篇 您的检索式：作者名="Gabello"

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		题名	作者	年代	出处	被引量
	1	Proton pump inhibitors: actions and -actions 显示文摘	Mullin JM Gabello M Murray LJ ct al	2009	Drug Discovery Today2009，14，1314：	1
	2	Transmucosal Gastric Leak Induced by Proton Pump Inhibitors显示文摘	Lisa J. Murray Melissa Gabello David S. Rudolph Christopher P. Farrell Melissa Morgan Aaron P. Martin James C. Underwood M. Carmen Valenzano James M. Mullin	2009	Digestive Diseases and Sciences2009，，7：	1
	3	Liquid phase hydrogenation of 1-alkeaea over Rh/Al PO4ard Rh/sepiolite catalysts 显示文摘	Gabello J A Campelo J M Garcia K	1993	MoL catal1993，78，：	1
	4	Proton pump in- hibitors: actions and reactions 显示文摘	Mullin JM Gabello M Murray LJ	2009	Drug Discovery Today2009，14，13：	1
	5	Omeprazole induces gastric transmucosal permeability to the peptide bradykinin显示文摘AIM:To investigate omeprazole-induced transepithelial gastric leak and its effects on the permeability of the peptides bradykinin and oxytocin.METHODS:Rat gastric corpus tissue was isolated and mounted in an Ussing chamber apparatus to evaluate the permeability of 3H-bradykinin,3H-oxytocin,and 14CEDTA in the presence or absence of omeprazole.Thinlayer chromatography was performed to identify any metabolic breakdown products of the peptides resulting from permeation through the gastric tissue,and thereby calculate the true flux of the peptide.RESULTS:The flux rate ofintact 3H-bradykinin increased substantially after omeprazole addition (109.5%) compared to the DMSO vehicle control (14%).No corresponding change in flux ofintact 3H-oxytocin was observed under the same conditions (11.9% and 6.4% in the DMSO-and omeprazole-treated conditions,respectively).After exposure to omeprazole,the flux rate of 14C-EDTA also increased dramatically (122.3%) compared to the DMSO condition (36.3%).CONCLUSION:The omeprazole-induced gastric leak allows for transmucosal permeability to charged molecules as well as non-electrolytes.This induced leak will allow certain peptides to permeate.	Melissa Gabello Mary Carmen Valenzano E Peter Zurbach James M Mullin	2010	World Journal of Gastroenterology2010，16，9：	1
	6	Proton pump inhibitors : actions and reactions 显示文摘	Mullin J M Gabello M Murray L J	2009	Drug Discov Today2009，14，1314：	1
	7	Proton pump inhibitors : actions and reactions 显示文摘	Mullin JM Gabello M Murray LJ	2009	Drug Discovery Today2009，14，1314：	1
	8	Proton pumpinhibitors : actions and reactions 显示文摘	MULLIN JM GABELLO M MURRAY LJ	2009	Drug Discovery Today2009，14，1314：	1

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