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| 1 | Corrigendum to “Properties improvement of SPEEK based proton exchange membranes by doping of ionic liquids and Y_2O_3”[Prog. Nat. Sci.: Mater. Int. 22 (1) (2012) 26-30] | Jianbin Chen a, Qiang Guo a, Dan Li a, Juying Tong a,b, Xia Li a a School of Materials Science and Engineering, Shanghai University, Shanghai 201800, China b School of Wenling, Zhejiang TV University, Wenling 317500, China | 2012 | Progress in Natural Science:Materials International2012，22，3： | 33 |
| 2 | 中国花生核心种质的建立及与ICRISAT花生微核心种质的比较显示文摘以中国花生种质资源数据库中记录的6390份花生资源为材料,以其基本数据、特征数据和评价数据为信息,采用分层分组聚类以及随机取样与必选资源相结合的方法,构建了由576份资源组成的花生核心种质,占基础收集品的9.01%。除出仁率外,核心种质与基础收集品种间的其他14个性状平均值和多样性指数差异均不明显,表明本研究建立的核心种质是有效的。与ICRISAT花生微核心种质的比较,中国花生资源在龙生型和珍珠豆型方面具有优势,叶片长、叶片宽、种子长、种子宽的遗传多样性丰富;而ICRISAT花生资源在多粒型和普通型方面具有优势,且植株高度和总分枝数的遗传多样性比中国花生资源丰富。 | 姜慧芳 任小平 廖伯寿 黄家权 雷永 陈本银 GUO B Z HOLBROOK C C UPADHYAYA H D | 2008 | 作物学报2008，34，1： | 28 |
| 3 | Down-regulation of Hsp90 could change cell cycle distribution and increase drug sensitivity of tumor cells显示文摘:AIM To construct Hsp90 antisense RNAeukaryotic expression vector, transfect it intoSGC7901 and SGC7901/VCR of MDR-type humangastric cancer cell lines, HCC7402 of humanhepatic cancer and Eel09 of human esophagealcancer cell lines, and to study the cell cycledistribution of the gene transected cells andtheir response to chemotherapeutic drugs.METHODS A I .03kb cDNA sequence of Hsp90Pwas obtained from the primary plasmid phHsp90by EcoR 1 and BamH I nuclease digestion andwas cloned to the EcoR 1 and BamH 1 site ofthe pcDNA by T4DNA ligase and an antisenseorientation of Hsp900 expression vector wasconstructed. The constructs were transfectedwith lipofectamine and positive clones wereselected with G418. The expression of RNA wasdetermined with dot blotting and RNaseprotection assay, and the expression of Hsp90protein determined with Western blot. Cell cycledistribution of the transfectants was analyzedwith flow cytometry, and the drug sensitivity ofthe transfectants to adriamycin (ADR ),vincrinstine (VCR ), mitomycin (MMC ) andcyclophosphamide (CTX ) with MTT andintracellular drug concentration of thetransfectants was determined with flowcytometry.RESULTS In EcoR 1 and BamH I restrictionanalysis, the size and the direction of the clonedsequence of Hsp900 remained what had beendesigned and the gene constructs were namedpcDNA-Hsp90. AH^SGC7901, AH^SGC7901/ VCR,AH-HCC7402 and AH-Eel09 cell clones allexpressed Hsp90 anti--sense RNA. Theexpression of Hsp90 was down--regulated in AHSGC7901, AH--SGC7901/ VCR, AH-HCC7402 andAH--Eel09 cell clones. Cell cycle distribution waschanged differently. In AH-SGC7901/ VCR andAH-Ec109 cells, G, phase cells were increased; Sphase and G, phase cells were decreased ascompared with their parental cell lines. In AHSGC7901 cell, G, phase cells were decreased, Qphase cells increased and S phase cells were notchanged, and in AH-HCC7402 cells G,, S and qphase cells remained unchanged as comparedwith their parental cell lines. The sensitivity ofAH--SGC7901, AH--SGC7901/ VCR, AH-HCC7402 andAH-Ec109 to chemotherapeutic drugs, thesensitivity ot AH--SGC7901/ VCR to ADR, VCR,MMC and CTX the sensitivity of AH-HCC7402 toADR and VCR, and the sensitivity of Eel09 toADR, VCR and CTX all increased as comparedwith their parental cell lines. The meanfluorescence intensity of ADR in AH--SGC7901,AH-SGC7901/ VCR, AH--HCC7402 and AH-Ec109was also significantly elevated (P< 0. 05).CONCLUSION Down-regulation of HsP90 couldchange cell cycle distribution and increase thedrug sensitivity of tumor cells. | Liu XL Xiao B Yu ZC Guo JC Zhao QC Xu L Shi YQ Fan DM | 1999 | World Journal of Gastroenterology1999，5，3： | 21 |
| 4 | The magnetic properties of Serbian loess and its environmental significance显示文摘This paper reports a loess-paleosol sequence located in the Danube River basin,Serbia,which formed at least since the latest part of the early Pleistocene,and before the paleomagnetic B/M boundary.Various magnetic parameters of the Serbian V-L1-V-S4 loess-paleosol sequence have been measured and analyzed in the Titel Loess Plateau.These parameters show a very similar magnetic behavior compared with that of the Chinese loess.There is a general positive relationship between magnetic susceptibility() and pedogenesis.The main contributors to are the magnetic grains of SP(superparamagnetic) and SD(single domain) magnetic domains,while MD(multi domain) contributes only a small percentage.The difference in between loess and paleosol mainly is caused by pedogenesis.The very fine magnetic minerals increase gradually with increasing soil development(from loess to soil),and they lead to higher.The thermomagnetic curves show thatmagnetic minerals in the loess layers are magnetite and maghemite,both providing a major contribution to.In contrast the paleosol layers mainly are composed of magnetite,with almost no or a very small amount of maghemite,as implied by a reversible thermomagnetic behavior.This indicates that pedogenic conditions during V-S3 and V-S4 strong soil development have resulted in maghemite that is no longer stable,and has been resolved or converted to other stable phase minerals.This likely indicates that soil moisture during V-S3 and V-S4 development exceeded a critical condition of maghemite stability. | LIU XiuMing LIU Zhi Lü Bin MARKOVI S B CHEN JiaSheng GUO Hui MA MingMing ZHAO GuoYong FENG Hua | 2013 | Chinese Science Bulletin2013，58，3： | 7 |
| 5 | 胃肠道恶性神经外胚层肿瘤:19例临床病理、免疫组化和分子分析显示文摘胃肠道恶性神经外胚层肿瘤临床非常罕见,目前对其具体发病机制尚不清楚。该文旨在分析胃肠道恶性神经外胚层肿瘤的临床病理特征、治疗及预后。该文收集19例胃肠道恶性神经外胚层肿瘤患者,平均肿瘤直径为4.2 cm。肿瘤最常见的原发部位为小肠(57.9%),其次为胃(15.8%)、结肠(10.5%)、回盲部(5.3%)、食管下端(5.3%)和肛管(5.3%)。 | Chang B Yu L Guo W W 魏建国(摘译) 方三高(审校) | 2020 | 临床与实验病理学杂志2020，36，1： | 5 |
| 6 | High doses of α-galactosylceramide potentiate experimental autoimmune encephalomyelitis by directly enhancing Th17 response显示文摘伪 - Galactosylceramide (伪 - GC ) 广泛地被知道激活不变的自然漂亮 T (iNKT ) 压制髓磷脂的房间抗原特定的 Th1 回答,保护易受影响的老鼠免于试验性的自体免疫的脑脊髓炎(EAE ) 。这里,我们表明那高加重,而非改善的伪 - GC 开 EAE 的意外发现。当与高剂量的伪 - GC 对待的 MOG35-55-specific T 房间被变成 na 时,类似的结果被观察 ? ve syngeneic 接受者老鼠。进一步的学习证明伪 - GC 的高剂量直接通过 STAT3 的 phosphorylation 和 NF-魏 B 的激活由 CD4+CD44+ 记忆 T 房间的激活提高 Th17 和 Th1 反应。不同于由伪 - GC 的低剂量的 iNKT 房间的激活,伪 - GC 的高剂量直接交往了, CD1d 在 T 房间上表示了并且激活 Th17 和 Th1 房间。而且,介绍抗原的房间(APC ) 主要表示 CD1d1,而 CD4+ T 房间快车 CD1d2 的多数。由 RNAi 的 CD1d1 或 CD1d2 基因表示击倒分别地防碍 iNKT 或 Th17/Th1 房间的激活。因此,伪 - GC 处理能改善或变得更坏由雇佣取决于剂量的 APC 或 Th17/Th1 房间的 EAE 使用了。 | Gaochao Qian Xia Qin Ying Qin Zang Baoxue Ge Taylor B Guo Bing Wan Lei Fang Jingwu Z Zhang | 2010 | Cell Research2010，20，4： | 3 |
| 7 | ^(99m)Tc-AMD3100:A novel potential receptor-targeting radiopharmaceutical for tumor imaging显示文摘The chemokine CXCR4 receptor is over-expressed in a wide variety of tumors.In this study,AMD3100,which was a prototype non-peptide antagonist of CXCR4 receptor,was labeled with ^(99m)Tc.^(99m)Tc-AMD3100 was verified by thin layer radio chromatography(TLRC).The tumor-localizing properties of ^(99m)Tc-AMD3100 were evaluated and proved in mice bearing Hep-G2 tumor xenograft.^(99m)Tc-AMD3100 was a promising,novel receptor-specific radiopharmaceutical with potential application in the imaging of human tumors. | Jin Ming Zhang~(a,),Jia He Tian~a,Tian Ran Li~a, Hai Yu Guo~a,Li Shen~b a Department of Nuclear Medicine,The PLA General Hospital,Beijing,100853,China b Peking University Health Science Center,Beijing,100191,China | 2010 | Chinese Chemical Letters2010，21，4： | 3 |
| 8 | ZrO_2 strengthened NiAl/Cr(Mo,Hf) composite fabricated by powder metallurgy | L.Y. Sheng a,b, J.T. Guo c, T.F. Xi a,b, B.C. Zhang c, H.Q. Ye c a PKU-HKUST ShenZhen-Hong Kong Institution, Shenzhen 518057, China b College of Engineering, Peking University, Beijing 100871, China c Institute of Metal Research, Chinese Academy of Sciences, Shenyang 110016, China | 2012 | Progress in Natural Science:Materials International2012，22，3： | 3 |
| 9 | A novel method for Co(Ⅱ) and Cu(Ⅱ) analysis by capillary electrophoresis with chemiluminescence detection显示文摘Based on the fact that some metal ions can catalyze the chemiluminescence(CL)reaction of luminol with K3Fe(CN)6,a novel capillary electrophoresis CL method was developed for the determination of Co(Ⅱ)and Cu(Ⅱ).The separation was carried out with a 10 mmol/L sodium acetate solution containing 0.8 mmol/L luminol and 2.0 mmol/Lα-HIBA(adjusted to pH 4.8 by HAc solution).The post-capillary reagent was 2.0 mmol/L K3Fe(CN)6 which was adjusted to pH 13.0 by NaOH solution.Under the optimum conditions,the detection limits(S/N=3)for Co(Ⅱ)and Cu(Ⅱ)were 7.5×10-11mol/L and 7.5×10-9mol/L,with the linear range of 7.5×10-9mol/L to 1.0×10-6mol/L and 7.5×10-8mol/L to 5.0×10-5mol/L, respectively. | Xiao Ming Guo~a Xiang Dong Xu~(a,b) Hui Jing Zhang~a Yong Gang Hu~(a,*) Jie Zhang~a a Institute of Environmental Science & Engineering,Huazhong University of Science and Technology,Wuhan 430074,China b Department of Chemistry,Huazhong University of Science and Technology,Wuhan 430074,China | 2007 | Chinese Chemical Letters2007，18，9： | 3 |
| 10 | Optimal birth control of population dynamics 显示文摘 | Chan W L Guo B Z | 1990 | J Math Anal Appl1990，146，2： | 2 |
| 11 | The main projects and development status of noise forecasting and controlling on working face in coal mine显示文摘Noise from the machine on coal working face seriously influenced the miners' physical and mental health, and also, due to the noise, there may be a major hidden danger in safety from accidents as all safety warning signals may be masked by the noise. This paper summarized the features of mine environmental noise on working face, such as the variety of noise sources, the continuity of high intensity and slow attenuation in narrow space, etc.The main projects about noise forecasting and controlling on working face was emphatically expounded;the development status about mines machinery noise mechanism and environmental noise acoustic characteristics of space-time of these main research topics were also introduced. | PENG You-duo GUO Ying-fu WU Li-tao LI Xin XIE Wei-hua Dhillon B S | 2010 | Journal of Coal Science & Engineering(China)2010，16，2： | 2 |
| 12 | Influence of Eutrophication on the Distribution of Total Mercury and Methylmercury in Hydroelectric Reservoirs显示文摘 | Meng Bo Feng X B Chen C X Qiu G L Sommar J Guo Y N Liang P Wan Q | 2010 | EN2010，，5： | 2 |
| 13 | Yes-associated protein (YAP65) in relation to Smad7 expression in humanpancreatic ductal adenocarcinoma显示文摘 | Junchao Guo J?rg Kleeff Yupei Zhao Junsheng Li Thomas Giese Irene Esposito Markus Büchler Murray Korc Helmut Friess | 2006 | International Journal of Molecular Medicine2006，，5： | 2 |
| 14 | 术中应用荧光素钠有利于胶质母细胞瘤浸润边缘的手术切除(英文)显示文摘Objective Extent of resection is an important prognostic factor in patients undergoing surgery for glioblastoma( GBM).Recent evidence suggests that intravenously administered fluorescein sodium associates with tumor tissue,facilitating safe maximal resection of GBM. In this study,the authors evaluate the safety and utility of intraoperative fluorescein guidance for the prediction of histopathological alteration both in the contrast-enhancing( CE) regions,where this relationship has been established,and into the nonCE( NCE),diffusely infiltrated margins. Methods Thirty-two patients received fluorescein sodium( 3 mg/kg) intravenously prior to resection. Fluorescence was intraoperatively visualized using a Zeiss Pentero surgical microscope equipped with a YELLOW 560 filter.Stereotactically localized biopsy specimens were acquired from CE and NCE regions based on preoperative MRI in conjunction with neuronavigation. The fluorescence intensity of these specimens was subjectively classified in real time with subsequent quantitative image analysis,histopathological evaluation of localized biopsy specimens,and radiological volumetric assessment of the extent of resection.Results Bright fluorescence was observed in all GBMs and localized to the CE regions and portions of the NCE margins of the tumors,thus serving as a visual guide during resection. Gross-total resection( GTR) was achieved in 84% of the patients with an average resected volume of 95%,and this rate was higher among patients for whom GTR was the surgical goal( GTR achieved in 93. 1% of patients,average resected volume of 99. 7%). Intraoperative fluorescein staining correlated with histopathological alteration in both CE and NCE regions,with positive predictive values by subjective fluorescence evaluation greater than 96% in NCE regions. Conclusions Intraoperative administration of fluorescein provides an easily visualized marker for glioma pathology in both CE and NCE regions of GBM. These findingssupport the use of fluorescein as a microsurgical adjunct for guiding GBM resection to facilitate safe maximal removal. | Neira JA Ung TH Sims J Malone HR Chow DS Samanamud JL Zanazzi GJ Guo X Bowden SG Zhao B Sheth SA McKhann GM 2nd Sisti MB Canoll P D'Amico RS Bruce JN | 2016 | 中华神经外科疾病研究杂志2016，15，5： | 2 |
| 15 | Unsatisfying antiviral therapeutic effect in patients with mother-tochild transmissed chronic hepatitis B virus infection: a prospective multi-center clinical study显示文摘Background:Few data are available regarding the progression of liver disease and therapeutic efficacy in chronic hepatitis B(HBV)carriers infected by mother-to-child transmission(MTCT).This study aimed to investigate these two aspects by comparing the adult chronic HBV carriers in MTCT group with those in horizontal transmission group.Methods:The 683 adult chronic HBV patients qualified for liver biopsy including 191 with MTCT and 492 with horizontal transmission entered the multi-center prospective study from October 2013 to May 2016.Biopsy results from 217 patients at baseline and 78 weeks post antiviral therapy were collected.Results:Patients infected by MTCT were more likely to have e antigen positive(68.6%vs.58.2%,x^2=-2.491,P=0.012)than those with horizontal transmission.However,in patients with MTCT,levels of alkaline phosphatase(ALP)(P=0.031),Fibroscan(P=0.013),N-terminal propeptide of Type III procollagen(PIIINP)(P=0.014),and Laminin(LN)(P=0.006)were high,in contrast to the patients with horizontal transmission for whom the levels of albumin(ALB)(P=0.041),matrix metalloproteinase-3(MMP-3)(P=0.001)were high.The 47.2% of patients with MTCT and 36.8%of those with horizontal transmission had significant liver fibrosis(P=0.013).Following antiviral therapy for 78 weeks,21.2%and 38.0%patients with MTCT and horizontal transmission acquired hepatitis B e antigen(HBeAg)clearance,respectively(P=0.043),and the virological response rates were 54.7%and 74.1%in the MTCT and horizontal groups,respectively(P=0.005).MTCT was a risk factor for HBeAg clearance and virological response.Conclusion:Adult patients with MTCT were more prone to severe liver diseases,and the therapeutic efficacy was relatively poor,which underlined the importance of earlier,long-term treatment and interrupting perinatal transmission. | Jun Li Xiao-Qin Dong Zhao Wu An-Lin Ma Shi-Bin Xie Xu-Qing Zhang Zhan-Qing Zhang Da-Zhi Zhang Wei-Feng Zhao Guo Zhang Jun Cheng Qing Xie Jun Li Zhi-Qiang Zou Ying-Xia Liu Gui-Qiang Wang Hong Zhao China Hepatitis B Related Fibrosis Assessment Research Group | 2019 | Chinese Medical Journal2019，，22： | 2 |
| 16 | Piezoelectric immunosensor for SARS-associated coronavirus in Sputum显示文摘 | Zuo B L Li S M Guo Z | 2004 | Anal Chem2004，76，： | 1 |
| 17 | Soil carbon stocks and land use change: a meta analysis 显示文摘 | GUO L B GIFFORD R M | 2002 | Global Change Biology2002，8，4： | 1 |
| 18 | Bcl-G,a novel pro-apoptotic member of the Bcl-2 family显示文摘 | Guo B Godzik A Reed J C | 2001 | J Biol Chem2001，，4： | 1 |
| 19 | Stress corrosion cracking of pipeline steel in soil environments of eastern china显示文摘 | Li G F Huang C B Guo H | 2007 | Key Engineering Materials2007，，： | 1 |
| 20 | Microtia: ear reconstruction using tissue expander and autogenous costal cartilage 显示文摘 | PAN B JIANG H GUO D | 2008 | J Plast Reconstr Aesthet Surg2008，61，： | 1 |
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