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| 1 | Clinical value of rapid urine trypsinogen-2 test strip, urinary trypsinogen activation peptide, and serum and urinary activation peptide of carboxypeptidase B in acute pancreatitis显示文摘AIM: To assess the usefulness of urinary trypsinogen-2 test strip, urinary trypsinogen activation peptide (TAP),and serum and urine concentrations of the activation peptide of carboxypeptidase B (CAPAP) in the diagnosisof acute pancreatitis.METHODS: Patients with acute abdominal pain and hospitalized within 24 h after the onset of symptoms were prospectively studied. Urinary trypsinogen-2 was considered positive when a clear blue line was observed (detection limit 50 μg/L). Urinary TAP was measured using a quantitative solid-phase ELISA, and serum and urinary CAPAP by a radioimmunoassay method.RESULTS: Acute abdominal pain was due to acute pancreatitis in 50 patients and turned out to be extrapancreatic in origin in 22 patients. Patients with acute pancreatitis showed significantly higher median levels of serum and urinary CAPAP levels, as well as amylase and lipase than extrapancreatic controls. Median TAP levels were similar in both groups. The urinary trypsinogen-2 test strip was positive in 68% of patients with acute pancreatitis and 13.6% in extrapancreatic controls (P<0.01). Urinary CAPAP was the most reliable test for the diagnosis of acute pancreatitis (sensitivity 66.7%, specificity 95.5%, positive and negative predictive values 96.6% and 56.7%, respectively), with a 14.6 positive likelihood ratio for a cut-off value of 2.32 nmol/L.CONCLUSION: In patients with acute abdominal pain,hospitalized within 24 h of symptom onset, CAPAP in serum and urine was a reliable diagnostic marker of acute pancreatitis. Urinary trypsinogen-2 test strip showed a clinical value similar to amylase and lipase.Urinary TAP was not a useful screening test for the diagnosis of acute pancreatitis. | Jesús Sáez Juan Martínez Celia Trigo José Sánchez-Payá Luis Compay Raquel Laveda Pilar Grió Cristina García Miguel Pérez-Mateo | 2005 | World Journal of Gastroenterology2005，11，46： | 21 |
| 2 | Synthesis and structure of a new macrocyclic polyhydroxylated gadolinium chelate used as a contrast agent for magnetic resonance imaging 显示文摘 | Platzek J Blaszkiewicz P Gries H | 1997 | Inorg Chem1997，36，： | 2 |
| 3 | Reduction in airway complications after lung transplantation with novel anastomotic technique显示文摘 | Fitzsullivane E Gries CJ Phelan P | 2011 | The Annals of Thorac- ic Surgery2011，92，1： | 1 |
| 4 | Transcriptional regulation of scar gene expression in primary astrocytes显示文摘 | GRIS P TIGHE A LEVIN D | 2007 | Glia2007，55，11： | 1 |
| 5 | Reduction of graft-versus-host disease by histone deacetylase inhibitor suberonylanilide hydroxamic acid is associated with modulation of inflammatory cytokine milieu and in- volves inhibition of STAT1 显示文摘 | Leng C Gries M Ziegler J Lokshin A Mascagni P Lentzsch S | 2006 | Exp Hematol2006，34，： | 1 |
| 6 | Serial blood lactate levels can predict the development of multiple organ failure following septic shock显示文摘 | Bakker J Gris P Coffernils M | 1996 | Am J Surg1996，171，2： | 1 |
| 7 | The ultraviolet filter 3-benzylidene camphor adversely affects reproduction in fathead minnow 显示文摘 | Kunz P Y Gries T Fent K | 2006 | Toxicological Sciences2006，93，2： | 1 |
| 8 | Steam sterilization and automatic dispensing of flude oxyglucose(FDG)for injection显示文摘 | Karwath P Sartor J Gries W | 2005 | Appl Radiat Isot2005，62，4： | 1 |
| 9 | Serial blood lactate levels can predict the development of multiple organ failure following septic shock 显示文摘 | Bakker J Gris P Coffemils M | 1996 | Am J Surg1996，171，2： | 1 |
| 10 | Hierarchical spatial modeling and prediction of multiple soil nutrients and carbon concentrations 显示文摘 | MAJUMDAR A KAYE J P GRIES C | 2008 | Communication in Statistics-Simulation and Computation2008，37，： | 1 |
| 11 | Transcriptional regulation of scar gene expression in primary astrocytes显示文摘 | Gris P Tighe A Levin D | | 0，，： | 1 |
| 12 | Steam sterilization and automatic dispensing of fludeoxyglucose(FDG) for injection显示文摘 | KARWATH P SARTOR J GRIES W | 2005 | Appl Radiat Isot2005，62，4： | 1 |
| 13 | Serial blood lactate levels can predict the development of multiple organ failure following septic shock显示文摘 | Gris P Coffernils M | 1996 | Am J Surg1996，171，22： | 1 |
| 14 | Toward a Social Psychology of Globalization显示文摘 | Chiu C.Y Gries P Leung A.K.Y | | 0，，： | 1 |
| 15 | Serial blood lactate levels predict the development of multiple organ failure following septic shock显示文摘 | Bakker J Gris P Coffemils M | 1996 | Am J Surg1996，171，2： | 1 |
| 16 | Environmental enrichment improves behavior, cognition, and brain functional markers in young senescence-accelerated prone mice (SAMP8) 显示文摘 | Gri an-Ferr6 C P~rez-C~ceres D Guti6rrez-Zetina SM | 2015 | Mol Neurobiol2015，，： | 1 |
| 17 | Acute and long term respiratory damage following inhalation of ammonia 显示文摘 | Lduc D Gris P Lheureux P | 1992 | Thoax1992，47，9： | 1 |
| 18 | Veno-arterial carbon dioxide gradient in human septic shock显示文摘 | Bakker J Vincent JL Gris P | 1992 | Chest1992，101，： | 1 |
| 19 | Reduction in airwaycomplications after lung transplantation with novel anastomotictechnique显示文摘 | FitzSullivan E Gries CJ Phelan P | 2011 | Ann Thorac Surg2011，92，1： | 1 |
| 20 | Serial blood lactate levels can predict the development of multiple organ failure following septic shock显示文摘 | Bakker J Gris P Coffernils M | 1996 | Am J Surg1996，171，2： | 1 |
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