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| 1 | Hepatitis delta virus: From infection to new therapeutic strategies显示文摘The hepatitis delta virus(HDV)is a small RNA virus that encodes a single protein and which requires the hepatitis B virus(HBV)-encoded hepatitis B surface antigen(HBsAg)for its assembly and transmission.HBV/HDV co-infections exist worldwide and show a higher prevalence among selected groups of HBV-infected populations,specifically intravenous drug users,practitioners of high-risk sexual behaviours,and patients with cirrhosis and hepatocellular carcinoma.The chronic form of HDV-related hepatitis is usually severe and rapidly progressive.Patterns of the viral infection itself,including the status of co-infection or super-infection,virus genotypes(both for HBV and HDV),and persistence of the virus’replication,influence the outcome of the accompanying and manifested liver disease.Unfortunately,disease severity is burdened by the lack of an effective cure for either virus type.For decades,the main treatment option has been interferon,administered as mono-therapy or in combination with nucleos(t)ide analogues.While its efficacy has been reported for different doses,durations and courses,only a minority of patients achieve a sustained response,which is the foundation of eventual improvement in related liver fibrosis.The need for an efficient therapeutic alternative remains.Research efforts towards this end have led to new treatment options that target specific steps in the HDV life cycle;the most promising among these are myrcludex B,which inhibits virus entry into hepatocytes,lonafarnib,which inhibits farnesylation of the viral-encoded LHDAg large hepatitis D antigen,and REP-2139,which interferes with HBsAg release and assembly. | Grazia A Niro Arianna Ferro Francesca Cicerchia Isabella Brascugli Marilena Durazzo | 2021 | World Journal of Gastroenterology2021，27，24： | 2 |
| 2 | Validation of RT-PCR assays for molecular characterization of porcine teschoviruses and enteroviruses 显示文摘 | La Rosa G Muscillo M Di Grazia A | 2006 | J Vet Med B2006，53，6： | 1 |
| 3 | Multiple chondromatous hamartomas of the lung显示文摘 | Bini A Grazia M Petrella F Chittolini M | | 0，，： | 1 |
| 4 | A isotope method for meas- urement of intestinal absorption of calcium in man显示文摘 | DE GRAZIA J A | 1965 | J Lab Clin Med1965，66，5： | 1 |
| 5 | Conversation galante:how the immune and the neuroendocrine systems talk to each other显示文摘 | di Comite G Grazia Sabbadini M Corti A | 2007 | Autoimmun Rev2007，7，1： | 1 |
| 6 | Prenatal diagnosis and pr ognostic value of human cytomegalovirus load and IgM antibody respose in blood of congenitallyinfected fetuses显示文摘 | Grazia RM Zavattoni M Sarasini A | 1999 | J Infect Dis1999，180，： | 1 |
| 7 | Functional outcome of ischemic and hemorrhagic stroke patients after inpatient rehabilitation:a matched comparison显示文摘 | Stefano P Gabriella A Maria Grazia G | 2003 | Stroke2003，34，： | 1 |
| 8 | Induction of apoptosis and inhibition of cell proliferation by survivin gene targeting 显示文摘 | Grazia Ambrosini Colette A | 1998 | J Biol Chem1998，273，11： | 1 |
| 9 | Amniotic membrane : separation of amniotic mesodernl from amniotic epithelium and isola- tion of their respective mesenchymal stromal and epithelial cells 显示文摘 | BARBATI A GRAZIA M M SIDONI A | 2012 | Curr Protoc Stem Cell Biol2012，1，8： | 1 |
| 10 | Mesenchymal stem cells inhibit natural killer cell proliferation, cytotoxieity and cytokine production: role of indoleamine 2, 3-dioxy-genase and prostaglandin E2显示文摘 | Grazia M S Heba A Flavio B | 2009 | Abstracts2009，16，3： | 1 |
| 11 | Efficacy and safety of dabigatran compared with warfarin at different levels of international normalised ratio control for stroke prevention in atrial fibrillation: an analysis of the RE-LY trial显示文摘 | Lars Wallentin Salim Yusuf Michael D Ezekowitz Marco Alings Marcus Flather Maria Grazia Franzosi Prem Pais Antonio Dans John Eikelboom Jonas Oldgren Janice Pogue Paul A Reilly Sean Yang Stuart J Connolly | 2010 | The Lancet . 2010 (9745)2010，，9745： | 1 |
| 12 | Validation of rt- PCR assays for molecular characterization of porcine teschoviruses and enteroviruses显示文摘 | La Rosa G Muscillo M Di Grazia A | 2006 | JVetMed B Infect Dis Vet Public Health2006，53，6： | 1 |
| 13 | Effect of bosentan upon pulmonary hypertension in chronic obstructive pulmonary disease显示文摘 | Valerio G Braceiale P Grazia D'Agostino A | 2009 | Ther Adv Respir Dis2009，3，1： | 1 |
| 14 | Multiple chondromatous hamartoma of the lung显示文摘 | Grazia M Petrella F | 2002 | Int Cardiovasc Thorac Surg2002，1，： | 1 |
| 15 | Unmanipulated haploidentical transplants compared with other alternative donors and matched sibling grafts 显示文摘 | Raiola AM Dominietto A di Grazia C | 2014 | Biol Blood Marrow Transplant2014，20，10： | 1 |
| 16 | Anaesthesia and autologous transfusion显示文摘 | Borghi B Bassi A Grazia M | 1995 | Int J Artif Organs1995，18，： | 1 |
| 17 | Evanescent wave absorption spectroscopy by means of bi-tapered multimode optical fibers显示文摘 | GRAZIA A RICCARDO M CIACCHERI F L | 1998 | Applied Spectroscopy1998，52，4： | 1 |
| 18 | Parry-Romberg syndrome with migraine and intracranial aneurysm显示文摘 | Pichiecchio A Uggetti C Grazia Egitto M | 2002 | Neurology2002，59，4： | 1 |
| 19 | Myoendothelial differentiation of human umbilical cord blood-derived stem cells in ischemic limb tissues显示文摘 | PESCE M ORLANDI A GRAZIA M | 2003 | Circ Res2003，93，1： | 1 |
| 20 | Amniotic membrane:separa-tion of amniotic mesoderm from amniotic epithelium and isolation of their respective mesenchymal stromal and epithelial cells显示文摘 | Barbati A Grazia Mameli M Sidoni A | 2012 | Curr Protoc Stem Cell Biol2012，1，8： | 1 |
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