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	题名	作者	年代	出处	被引量
1	Adjuvant therapy sparing in rectal cancer achieving complete response after chemoradiation显示文摘AIM:To evaluate the long-term results of conventional chemoradiotherapy and laparoscopic mesorectal excision in rectal adenocarcinoma patients without adjuvant therapy.METHODS:Patients with biopsy-proven adenocarcinoma of the rectum staged cT3-T4 by endoscopic ultrasound or magnetic resonance imaging received neoadjuvant continuous infusion of 5-fluorouracil for five weeks and concomitant radiotherapy.Laparoscopic surgery was planned after 5-8 wk.Patients diagnosed with ypT0N0 stage cancer were not treated with adjuvant therapy according to the protocol.Patients with ypT1-2N0 or ypT3-4 or N+were offered 5-fluorouracil-based adjuvant treatment on an individual basis.An external cohort was used as a reference for the findings.RESULTS:One hundred and seventy six patients were treated with induction chemoradiotherapy and 170underwent total mesorectal excision.Cancer staging of ypT0N0 was achieved in 26/170(15.3%)patients.After a median follow-up of 58.3 mo,patients withypT0N0 had five-year disease-free and overall survival rates of 96%(95%CI:77-99)and 100%,respectively.We provide evidence about the natural history of patients with localized rectal cancer achieving a complete response after preoperative chemoradiation.The inherent good prognosis of these patients will have implications for clinical trial design and care of patients.CONCLUSION:Withholding adjuvant chemotherapy after complete response following standard neoadjuvant chemoradiotherapy and laparoscopic mesorectal excision might be safe within an experienced multidisciplinary team.	Xabier García-Albéniz Rosa Gallego Ralf Dieter Hofheinz Gloria Fernández-Esparrach Juan Ramón Ayuso-Colella Josep Antoni Bombí Carles Conill Miriam Cuatrecasas Salvadora Delgado Angels Ginés Rosa Miquel Mario Pagés Estela Pineda Verónica Pereira Aarón Sosa Oscar Reig Iván Victoria Luis Feliz Antonio María de Lacy Antoni Castells Iris Burkholder Andreas Hochhaus Joan Maurel	2014	World Journal of Gastroenterology2014，20，42：	5
2	Hepatic Expression of CXC Chemokines Predicts Portal Hypertension and Survival in Patients With Alcoholic Hepatitis显示文摘	Marlene Dominguez Rosa Miquel Jordi Colmenero Montserrat Moreno Joan–Carles García–Pagán Jaime Bosch Vicente Arroyo Pere Ginès Juan Caballería Ramón Bataller	2009	Gastroenterology2009，，5：	3
3	A quantitative,systematic review of randomized controlled trials of ephedrine versus phenylephrine for the management of hypotension during spinal anesthesia for cesarean delivery显示文摘	Lee A Ngan Kee WD Gin T	2002	Anesth Analg2002，94，4：	1
4	A dose-response meta-analysis of prophylactic intravenous ephedrine for the prevention of hypotension during spinal anesthesia for elective cesarean delivery 显示文摘	Lee A Ngan Kee WD Gin T	2004	Anesth Analg2004，98，2：	1
5	Vancemycin-resistant enterococci显示文摘	Gin A S Zhanel G G	1996	Annpharmacother1996，30，：	1
6	Study of the complexation behaviour of gliclazide with partially methylated β -cyclodextrin in solution and solid state显示文摘	J.R. Moyano Mar??a José Arias-Blanco J.M. Ginés F. Giordano	1997	International Journal of Pharmaceutics1997，，2：	1
7	Coronary artery disease in chronic kidney disease patients:assessing the evidence for diagnosis,screening and revascularization显示文摘	Saw J Levin A Gin K	2004	Can J Cardiol2004，20，8：	1
8	Changes in the cooling rate and medium improve the vascular function in cryopreserved porcine femoral arteries显示文摘	Montserrat Rigol Magda Heras Anna Martínez María Jesús Zurbano Elba Agustí Eulàlia Roig José Luís Pomar Ginés Sanz	2000	Journal of Vascular Surgery2000，，5：	1
9	Cloud-point extraction of molybdenum in plants and determination by isotope dilution inductively coupled plasma mass spectrometry显示文摘	BELLATO A C GERVASIO A P GIN E M F	2005	J Anal At Spectrom2005，20，：	1
10	Effect of arbuscular mycorrhizal fungi on the acclimatization of micropropagated banana planters 显示文摘	YANO-MELO A M MAIA L C SAC GIN O J JR	1999	Mycorrhiza1999，9，2：	1
11	New endoscopic ultrasound (EUS) applications in lung cancer: evaluation of pa- tients with negative mediastinal CT and re-staging after neoadju- vant treatment显示文摘	Fern6ndez-Esparrach G Sendino O Gin s A	2011	Arch Bronconeumol2011，47，8：	1
12	On integrability of differential equations defined by the sum of homogeneous vector fields with degenerate infinity 显示文摘	Chavarriga J Garcla I A Gin J	2001	Int J Bifurcation and Chaos2001，11，3：	1
13	A quantitative, syste- matic review of randomized controlled trials of ephedrine versus phenylephrine for the management of hypotension during spinal anesthesia for cesarean delivery 显示文摘	LEE A NGAN KEE W D GIN T	2002	Anesth Analg2002，94，4：	1
14	Manipulating the taste-related compositionof strawberry fruits(Fragaria×ananassa)from different cultivars using deficit irrigation显示文摘	Gin'e BORDONABA J TERRY L A	2010	Food Chemistry2010，122，：	1
15	Incidence, predictive factors, and prognosis of the hepatorenal syndrome in cirrhosis with ascites显示文摘	Gin s A Escorsell A Gin s P	1993	Gastroenterology1993，105，1：	1
16	Diagnosis, prevention and treat- ment of hepatorenal syndrome in cirrhosis 显示文摘	Salerno F Gerbes A Gin s P	2007	Gut2007，56，9：	1
17	Type Ⅱ InAs/GaSb superlattice photovoltaic detectors with cutoff wavelength approaching 32 μm 显示文摘	WEI Y J GIN A RAZEGHI M	2002	Appl Phys Lett2002，81，：	1
18	Diagnosis,prevention and treatment of hepatorenal syndrome in cirrhosis显示文摘	Salerno F Gerbes A Ginès P		0，，09：	1
19	Uterine Rupture and Epidural Analgesia during Trial of Labour显示文摘	Rowbottom S J Critchley L A Gin T	1997	Anaesthesia1997，52，5：	1
20	Educating patients about anesthesia:a systematic review of randomized controlled trials of mediabased interventions显示文摘	Lee A Chui PT Gin T	2003	Anesth Analg2003，96，5：	1

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