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| 1 | Role of magnetic resonance imaging in the detection and characterization of solid pancreatic nodules: An update显示文摘Pancreatic ductal adenocarcinoma is the most common malignant tumor of the pancreas. The remaining pancreatic tumors are a diverse group of pancreatic neoplasms that comprises cystic pancreatic neoplasms, endocrine tumors and other uncommon pancreatic tumors. Due to the excellent soft tissue contrast resolution, magnetic resonance imaging(MRI) is frequently able to readily separate cystic from noncystic tumors. Cystic tumors are often easy to diagnose with MRI; however, noncystic non-adenocarcinoma tumors may show a wide spectrum of imaging features, which can potentially mimic ductal adenocarcinoma. MRI is a reliable technique for the characterization of pancreatic lesions. The implementation of novel motionresistant pulse sequences and respiratory gating techniques, as well as the recognized benefits of MR cholangiopancreatography, make MRI a very accurate examination for the evaluation of pancreatic masses. MRI has the distinctive ability of non-invasive assessment of the pancreatic ducts, pancreatic parenchyma, neighbouring soft tissues, and vascular network in one examination. MRI can identify different characteristics of various solid pancreatic lesions, potentially allowing the differentiation of adenocarcinoma from other benign and malignant entities. In this review we describe the MRI protocols and MRI characteristics of various solid pancreatic lesions. Recognition of these characteristics may establish the right diagnosis or at least narrow the differential diagnosis, thus avoiding unnecessary tests or procedures and permitting better management. | Najwa Al Ansari Miguel Ramalho Richard C Semelka Valeria Buonocore Silvia Gigli Francesca Maccioni | 2015 | World Journal of Radiology2015，7，11： | 9 |
| 2 | Clinical characteristics and prognostic impact of atrial fibrillation in patients with chronic heart failure显示文摘AIM To assess the prevalence, clinical characteristics and independent prognostic impact of atrial fibrillation(AF) in chronic heart failure(CHF) patients, and the potential protective effect of disease-modifying medications, particularly beta-blockers(BB). METHODS We retrospectively reviewed the charts of patients referred to our center since January 2004, and collected all clinical information available at their first visit. We assessed mortality to the end of June 2015. We compared patients with and without AF, and assessed the association between AF and all-cause mortality by multivariate Cox regression and Kaplan-Meyer analysis, particularly accounting for ongoing treatment with BB.RESULTS A total of 903 patients were evaluated(mean age 68 ± 12 years, 73% male). Prevalence of AF was 19%, ranging from 10% to 28% in patients ≤ 60 and ≥ 77 years, respectively. Besides the older age, patients with AF had more symptoms(New York Heart Association II-III 60% vs 44%), lower prevalence of dyslipidemia(23% vs 37%), coronary artery disease(28% vs 52%) and left bundle branch block(9% vs 16%). On the contrary, they more frequently presented with an idiopathic etiology(50% vs 24%), a history of valve surgery(13% vs 4%) and received overall more devices implantation(31% vs 21%). The use of disease-modifying medications(i.e., BB and ACE inhibitors/angiotensin receptor blockers) was lower in patients with AF(72% vs 80% and 71% vs 79%, respectively), who on the contrary were more frequently treated with symptomatic and antiarrhythmic drugs including diuretics(87% vs 69%) and digoxin(51% vs 11%). At a mean follow-up of about 5 years, all-cause mortality was significantly higher in patients with AF as compared to those in sinus rhythm(SR)(45% vs 34%, P value < 0.05 for all previous comparisons). However, in a multivariate analysis including the main significant predictors of allcause mortality, the univariate relationship between AF and death(HR = 1.49, 95%CI: 1.15-1.92) became not statistically significant(HR = 0.98, 95%CI: 0.73-1.32). Nonetheless, patients with AF not receiving BB treatment were found to have the worst prognosis, followed by patients with SR not receiving BB therapy and patients with AF receiving BB therapy, who both had similarly worse survival when compared to patients with SR receiving BB therapy.CONCLUSION AF was highly prevalent and associated with older age, worse clinical presentation and underutilization of disease-modifying medications such as BB in a population of elderly patients with CHF. AF had no independent impact on mortality, but the underutilization of BB in this group of patients was associated to a worse long-term prognosis. | Lorenzo Gigli Pietro Ameri Gianmarco Secco Gabriele De Blasi Roberta Miceli Alessandra Lorenzoni Francesco Torre Francesco Chiarella Claudio Brunelli Marco Canepa | 2016 | World Journal of Cardiology2016，8，11： | 4 |
| 3 | All-dielectric χ^(2) metasurfaces: recent progress显示文摘Optical metasurfaces,i.e.arrays of nanoantennas with sub-wavelength size and separation,enable the manipulation of light-matter interactions in miniaturized optical components with no classical counterparts.Six decades after the first ob-servation of the second harmonic generation(SHG)in bulk crystals,these devices are expected to break new ground in the field of nonlinear optics,shifting the focus from the phase matching approach achieved within long propagation dis-tances to that of near-field resonances interplay in leaky nanocavities.Here we review the recent progress in SHG with all-dielectric metasurfaces.We discuss the most used technological platforms which underpinned such advances and analyze different SHG control approaches.We finally compare their performances with other well-established technolo-gies,with the hope to delineate the current state-of-the-art and figure out a few scenarios in which these devices might soon offer unprecedented opportunities. | Carlo Gigli Giuseppe Leo | 2022 | Opto-Electronic Advances2022，5，7： | 3 |
| 4 | Physics-informed neural networks for diffraction tomography显示文摘We propose a physics-informed neural network(PINN)as the forward model for tomographic reconstructions of biological samples.We demonstrate that by training this network with the Helmholtz equation as a physical loss,we can predict the scattered field accurately.It will be shown that a pretrained network can be fine-tuned for different samples and used for solving the scattering problem much faster than other numerical solutions.We evaluate our methodology with numerical and experimental results.Our PINNs can be generalized for any forward and inverse scattering problem. | Amirhossein Saba Carlo Gigli Ahmed B.Ayoub Demetri Psaltis | 2022 | Advanced Photonics2022，4，6： | 2 |
| 5 | Rockfall seismic features analysis based on in situ tests:frequency, amplitude, and duration显示文摘In the seismic event classification,determining the seismic features of rockfall is significantly important for the automatic classification of seismic events because of the huge amount of raw data recorded by seismic stations in continuous monitoring. At the same time, the rockfall seismic features are still not completely understood.This study concentrates on the rockfall frequency content, amplitude(ground velocity), seismic waveform and duration analysis, of an artificial rockfall test at Torgiovannetto(a former quarry in Central Italy). A total of 90 blocks were released in the test, and their seismic signals and moving trajectories were recorded by four tri-axial seismic stations and four cameras, respectively. In the analysis processing,all the artificial rockfall signal traces were cut separately and the seismic features were extracted individually and automatically. In this study, the relationships between a) frequency content and impacted materials, b) frequency content and the distance between block releasing position and seismic station(source-receiver distance) were discussed. As a result, we found that the frequency content of rockfall focuses on 10-60 Hz and 80-90 Hz within a source-receiver distance of 200 m, and it is well correlated with impacted material and source-receiver distance. To evaluate the difference between earthquake and rockfall, 23 clear earthquake signals recorded in a seven month-long continuous seismic monitoring, carried out with the four seismic stations, were picked out, according to the Italian national earthquakes database(INGV). On these traces we performed the same analysis as in the artificial rockfall traces, and two parameters were defined to separate rockfall events from earthquake noise. The first one, the amplitude ratio, is related to the amplitude variation of rockfall between two stations and is greater than that of earthquakes, because of the higher attenuation occurring for rockfall events, which consists in high frequencies whereas for earthquakes it consists in low frequencies. The other parameter, the shape of waveform of signal trace, showed a significant difference between rockfall and earthquake and that could be a complementary feature to discriminate between both. This analysis of artificial rockfall is a first step helpful to understand the seismic characteristics of rockfall, and useful for rockfall seismic events classification in seismic monitoring of slope. | Liang FENG Veronica PAZZI Emanuele INTRIERI Teresa GRACCHI Giovanni GIGLI | 2019 | Journal of Mountain Science2019，16，5： | 2 |
| 6 | Marciani ma sleep microstructure and EEG epileptiform activity in patients with juvenile myoclonic显示文摘 | Gigli G Calia E | 1996 | Epilepsis1996，33，5： | 1 |
| 7 | Reactive blending of poly ( butylene suecinate) and poly (triethylene succinate): Characterization of the copolymers obtained 显示文摘 | Soccio M Lotti N Gigli M | 2012 | Polymer International2012，61，7： | 1 |
| 8 | Restless legs syndrome: diagnosis, epidemiology, classification and consequences显示文摘 | G. Merlino M. Valente A. Serafini G. L. Gigli | 2007 | Neurological Sciences2007，，1： | 1 |
| 9 | Semi-automatic extraction of rock mass structural data from high resolution LIDAR point clouds 显示文摘 | Giovanni Gigli Nicola Casagli | 2011 | International Journal of Rock Mechanics ~ Mining Sciences2011，48，2： | 1 |
| 10 | Effects oftrimetazidine on myocardial perfusion and left ventricularsystolic function in type 2 diabetic patients with ischemiccardiomyopathy 显示文摘 | Belardinelli R Cianci G Gigli M | 2008 | J Cardiovasc Pharmacol2008，51，6： | 1 |
| 11 | Non-myeloablative haploidentieal transplantation of unmanipulated, G-CSF mobilized peripheral blood stem cells with high dose post-transplant cyelophosphamide: fast engraftment, no evidence of graft rejection and low incidence of graft-versus-host-disease 显示文摘 | Pastano R Andreola G Gigli F | 2014 | Blood ( ASH annual meeting Abstracts )2014，124，21： | 1 |
| 12 | Effects of trimetazidine on myocardial perfusion and left ventricular systolic function in type 2 diabetic patients with i schemic cardiomyopathy 显示文摘 | Belardinelli R Cianci G Gigli M | 2008 | J Cardiovasc Pharmacol2008，51，61： | 1 |
| 13 | Extramedullary myeloid sarco- ma of the breast显示文摘 | Azim HA Jr Gigli F Pruneri G | 2008 | J Clin Oncol2008，26，： | 1 |
| 14 | Valproate-induced systemic lupus erythematosus in a patient with partial trisomy of chromosome 9 and epilepsy显示文摘 | Gigli GL Scalise A Pauri F | 1996 | Epilepsia1996，37，6： | 1 |
| 15 | Low dose velcade,thalidomide and Dexamtheasone (LD-VTD):an effective regimen for relapsed and refractory multiple Patients显示文摘 | Ciolli S Leoni F Gigli F | 2006 | Leukemia Lymphoma2006，47，1： | 1 |
| 16 | Study of structure and flavour release relationships in low moisture bakery products by means of the acoustic–mechanical combined technique and the electronic nose显示文摘 | Laura Piazza Jiabril Gigli Simona Benedetti | 2007 | Journal of Cereal Science2007，，2： | 1 |
| 17 | Incidence oftransient ischemic attack and early stroke risk validationof the ABCD2 score in an Italian population-based study显示文摘 | CANGELLI I JANES F GIGLI G L | 2011 | Stroke2011，42，10： | 1 |
| 18 | Semi-automatic extraction of rock mass structural data from high resolution LIDAR point clouds 显示文摘 | Giovanni Gigli Nicola Casagli | 2011 | International Journal of Rock Mechanics ~ Mining Sciences2011，48，2： | 1 |
| 19 | Effects of seizures,kindling,and carbamazepine on sleep organization in cats显示文摘 | Gigli GL Gotman J | 1992 | Epilepsia1992，33，： | 1 |
| 20 | Fractionation and characterization of a conjugate between a polymeric drug-carrier and the antitumor drug camptothecin 显示文摘 | MENDICHI R RIZZO V GIGLI M | 2002 | Bioconjug Chem2002，13，6： | 1 |
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