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| 1 | Identification of proteins involved in lignocellulose degradation using in gel zymogram analysis combined with mass spectroscopy-based peptide analysis of gut proteins from larval Asian Ionghorned beetles, Anoplophora glabripennis显示文摘 | Scott M. Geib Ming Tien Kelli Hoover | 2010 | Insect Science2010，17，3： | 5 |
| 2 | Knowledge-enabled customer relationship management: integrating customer relationship management and knowledge management concepts[1]显示文摘 | Henning Gebert Malte Geib Lutz Kolbe Walter Brenner | 2003 | Journal of Knowledge Management2003，，5： | 3 |
| 3 | Genetic vaccination with Flt3-L and GM-CSF as adjuvants: Enhancement of cellular and humoral mmune responses that results in protective immunity in a murine model of hepatitis C virus infection显示文摘AIM: To investigate whether transfection of plasmid DNA encoding these cytokines enhances both humoral and cellular immune responses to hepatitis C virus (HCV) in a murine model. METHODS: We established a tumor model of HCV infection using syngenic mouse myeloma cells stably transfected with NS5. Co-vaccination of DNA encoding granulocyte macrophage colony-stimulating factor (GM- CSF) and Flt-3 ligand together with a plasmid encoding for the HCV NS5 protein was carried out. Mice were sacrificed 14 d after the last immunization event with collection of spleen cells and serum to determine humoral and cellular immune responses. RESULTS: Co-vaccination of DNA encoding GM-CSF and Flt-3 ligand together with a plasmid encoding for the HCV NS5 protein induced increased antibody responses and CD4+ T cell proliferation to this protein. Vaccination with DNA encoding GM-CSF and Flt-3L promoted protection against tumor formation and/or reduction in mice co- immunized with cytokine-encoding DNA constructs. This suggests this strategy is capable of generating cytotoxic T lymphocyte activity in vivo. Following inoculation withplasmid DNA encoding Flt-3L, no increase in spleen size or in dendritic cell (DC) and natural killer cell numbers was observed. This was in contrast to a dramatic increase of both cell types after administration of recombinant Flt3-L in vivo. This suggests that vaccination with plasmid DNA encoding cytokines that regulate DC generation and mobilization may not promote unwanted side effects, such as autoimmunity, splenic fibrosis or hematopoietic malignancies that may occur with administration of recombinant forms of these proteins. CONCLUSION: Our data support the view that plasmid DNA vaccination is a promising approach for HCV immunization, and may provide a general adjuvant vaccination strategy against malignancies and other pathogens. | Jens Encke Jomo Bernardin Jasmin Geib Gocha Barbakadze Raymond Bujdoso Wolfgang Stremmel | 2006 | World Journal of Gastroenterology2006，12，44： | 2 |
| 4 | Knowledge-enabled customer relationship management: Integrating customer relationship management and knowledge management concepts显示文摘 | Gebert H Geib M Kolbe L | 2003 | Journal of Knowledge Management2003，7，5： | 1 |
| 5 | Cyclic strain induces reorgani- zation of integrin alpha 5 beta 1 and alpha 2 beta 1 in human umbilical vein endothelial cells 显示文摘 | YanoY Geibe J Sumpio B E | 1997 | J Cell Biochem1997，64，3： | 1 |
| 6 | High and selective CO2 uptake ina cobalt adeninate metal-organic framework exhibiting py-rimidine- and amino-decorated pores显示文摘 | An J Geib S J Rosi N L | 2010 | J Am Chem Soc2010，132，： | 1 |
| 7 | Effects of laccase on lignin depolymerization and enzymatic hydrolysis of ensiled corn stover显示文摘 | Chen Q Marshall M N Geib S M | 2012 | Bioresource technology2012，117，： | 1 |
| 8 | High and selective CO2uptake in a cobalt adeninate metal-organic framework exhibiting pyrimidine-and amino-decorated pores显示文摘 | An J Geib S J Rosi N L | 2010 | J Am Chem Soc2010，132，： | 1 |
| 9 | Thermal resistance of VCSEL′s bonded to integrated circuits显示文摘 | PU R WILMSEN C W GEIB K M | 1999 | IEEE Photonics Technology Letters1999，11，12： | 1 |
| 10 | Knowledge-enabled customer relationship management:integrating customer relationship and knowledge management concepts显示文摘 | GEBERT H GEIB M KOLBE L | | 0，，05： | 1 |
| 11 | Argatroban versus Lepirudin in critically ill patients (ALicia) : a randomized controlled trial 显示文摘 | Treschan T A Schaefer M S Geib J | 2014 | Crit Care2014，18，5： | 1 |
| 12 | Knowledge-enabled customer relationship management: integrating customer relationship management and knowledge management concepts[1]显示文摘 | Henning Gebert Malte Geib Lutz Kolbe Walter Brenner | 2003 | Journal of Knowledge Management2003，，5： | 1 |
| 13 | Effects of oxygen content on the properties of tantalum oxide films deposited by ion-beam sputtering显示文摘 | DEMIRYONT H SITES J R GEIB K | 1985 | Appl Opt1985，24，4： | 1 |
| 14 | The sulfurized InP surface显示文摘 | Wilmsen C W Geib K M Shin J | 1989 | J Vac Sci Technol B1989，7，： | 1 |
| 15 | Knowledge-enabled customer relationship management: integrating customer relationship management and knowledge management concepts 显示文摘 | GEBERT H GEIB M KOLBE L | 2003 | Journal of Knowledge Management2003，7，5： | 1 |
| 16 | Knowledge-enabled customer relationship management: integrating customer relationship management and knowledge management concepts 显示文摘 | Henning Gebert Mahe Geib | 2003 | Journal of Knowledge Management2003，7，5： | 1 |
| 17 | Middleware Challenges Ahead显示文摘 | Geibs K | 2001 | IEEE Computer2001，34，6： | 1 |
| 18 | Urbanization between compactness and dispersion:designing a spatial model for measuring 2D binary settlement landscape configurations显示文摘Measuring spatial patterns is a crucial task in spatial sciences.Multiple indicators have been developed to measure patterns in a quantitative manner.However,most comparative studies rely on relative comparisons,limiting their explanatory power to specific case studies.Motivated by advancements in earth observation providing unprecedented resolutions of settlement patterns,this paper suggests a measurement technique for spatial patterns to overcome the limits of relative comparisons.We design a model spanning a feature space based on two metrics-largest patch index and number of patches.The feature space is defined as‘dispersion index’and covers the entire spectrum of possible two-dimensional binary(settlement)patterns.The model configuration allows for an unambiguous ranking of each possible pattern with respect to spatial dispersion.As spatial resolutions of input data as well as selected areas of interest influence measurement results,we test dependencies within the model.Beyond,common other spatial metrics are selected for testing whether they allow unambiguous rankings.For scenarios,we apply the model to artificially generated patterns representing all possible configurations as well as to real-world settlement classifications differing in growth dynamics and patterns. | Hannes Taubenbock Michael Wurm Christian GeiB Stefan Dech Stefan Siedentop | 2019 | International Journal of Digital Earth2019，12，6： | 1 |
| 19 | High and selective CO2 uptake in a cobalt adeninate metal-organic framework exhibiting pyrimidine- and ami- no-decorated pores显示文摘 | An J Geib S J Rosi N L | 2010 | Journal of the American Chemical Society2010，132，1： | 1 |
| 20 | Decision networks for integrating the behaviors of virtual agents and avatars 显示文摘 | T Trias S Chopin B Reich M Moore N Badler B Webber C Geib | 1996 | IEEE VRAIS1996，，： | 1 |
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