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| 1 | Cultivation of human liver cell lines with microcarriers acting as biological materials of bioartificial liver显示文摘AIM To improve the Cultivation efficiency and yield of human liver cell line CL--l.METHODS High--density cultivation of CL--l onmicrocarriers was carried out with periodicobservation of their growth and proliferation.The specific functions of human liver cell werealso determined.RESULTS Cells of CL-1 cell line grew well onmicrocarrier Cytodex--3 and on the 7th day thepeak was reached. The amount of CLI cells was2.13 x 10’ and the total amount of albuminsynthesis reached 71 .23 ig, urea synthesis23 .32 mg and diazepam transformation 619 .7 ugrespectively. The yield of CL-l on microcarrierswas 49.3 times that of conventional cultivation.The amounts of albumin synthesis, ureasynthesis and diazepam transformation were39.8 times, 41 .6 times and 33.3 times those ofconventional Cultivation, respectively.CONCLUSION The human liver cell line CL--1 canbe Cultivated to a high density with Cytodex--3and has better biological functions. High-densityCultivation of CLI on microcarriers can act asthe biological material of bioartificial liver. | Gao Y Xu XP Hu HZ Yang JZ | 1999 | World Journal of Gastroenterology1999，5，3： | 13 |
| 2 | A PAT STUDY OF INFLUENCES OF PRECIPITATION ON DEFECTS AND ELECTRONIC DENSITY IN Al-Li-Cu-Mg-Zr ALLOYS显示文摘APATSTUDYOFINFLUENCESOFPRECIPITATIONONDEFECTSANDELECTRONICDENSITYINAlLiCuMgZrALLOYS①WuWeiming,GaoYingjun,LuoLixiong,DengW... | Wu, WM Gao, YJ Luo, LX Deng, W Xu, SJ Zhong, XP Jiang, XJ | 1997 | 中国有色金属学会会刊:英文版1997，7，1： | 2 |
| 3 | Angiopoietin-1 opposes VEGF-induced increase in endothelial permeability by inhibiting TRPC1-dependent Ca2+ influx显示文摘 | Jho D Mehta D Ahmmed G Gao XP Tiruppathi C Broman M | 2005 | Circ Res2005，96，12： | 1 |
| 4 | Caveolin - 1 regulates NF - kB activation and lung inflammatory response to sepsis induced by lipopo- lysaccharidel 显示文摘 | Garrean S Gao XP Brovkovych V | 2006 | J Immunol2006，177，7： | 1 |
| 5 | Inactivation of CDllb in a mouse transgenic model protects against sepsis -induced lung PMN infiltration and vascular injury显示文摘 | Gao XP Liu Q Broman M | 2005 | Physiol Genomics2005，21，2： | 1 |
| 6 | The clinical application studies of CT spinal angiography with 64-detector row spiral CT in diagnosing spi- nal vascular malformations显示文摘 | Gao SJ Zhang MW Liu XP | 2009 | Eur J Radiol2009，71，： | 1 |
| 7 | Toxoplasma infection in males withsterility in Shenyang,China显示文摘 | Qi R Su XP Gao XL | 2005 | Nat J Androl2005，11，7： | 1 |
| 8 | Jasmonic acod is involved in the water-stress-induced betaine accumulation in pear leaves显示文摘 | GAO XP WANG XF LU YF | 2004 | Plant Cell and Environment2004，27，： | 1 |
| 9 | Quantitative measurement to evaluate morphological changes of the corpus callosum in patients with subcortical ischemic vascular dementia显示文摘 | Wu XP Gao Y J Yang JL | 2015 | Acta Radiol2015，56，： | 1 |
| 10 | Expression and significance of heparanase and nm23-H1 in hepatocellular carcinoma显示文摘 | Liu YB Gao SL Chen XP | 2005 | World J Gastroenterol2005，11，： | 1 |
| 11 | Role of NADPH oxidase in the mechanism of lung neutrophil sequestration and microvessel injuryinduced by Gram-negative sepsis: studies in p47ph ox -/-and gp91phox -/-mice显示文摘 | Gao XP Standiford TJ Rahman A | 2002 | J Immunol2002，168，8： | 1 |
| 12 | Endothelial cell-restricted disruption of FoxM1 impairs endothelial repair following LPS-induced vascular injury显示文摘 | Zhao YY Gao XP Zhao YD | 2006 | J Clin Invest2006，116，9： | 1 |
| 13 | The redox-sensitive cation channel TRPM2 modulates phagocyte ROS production and inflammation显示文摘 | Di A Gao XP Qian F | 2012 | Nat Immunol2012，13，1： | 1 |
| 14 | A label-free and PCR-free electrochemical assay for multiplexed microRNA profiles by ligase chain reaction coupling with quantum dots barcodes显示文摘 | Zhu WY Su XP Gao XY | 2014 | Biosens Bioelectron2014，53，： | 1 |
| 15 | Effect of minocycline on carotid atherosclerotic plaques显示文摘 | Gao JH Gao XP Pan SY | 2013 | Neurol Res2013，9，35： | 1 |
| 16 | Endothelial cell-restricted disruption of FoxM1 impairs endothelial repair following LPS-induced vascular injury 显示文摘 | Zhao Y-Y Gao XP Zhao YD | 2006 | J Clin Invest2006，116，9： | 1 |
| 17 | Suggestion on the establishment of the system of organ donation after citizen's death 显示文摘 | Yang SL Gao XP Tan JM | 2015 | Organ Transplant2015，6，4： | 1 |
| 18 | Guest-controlling effects on ER behaviors of 13-cyclodextrin polymer 显示文摘 | GAO ZW ZHAO XP | 2005 | J Colloid Interface Sci2005，289，1： | 1 |
| 19 | Expression and signifycance of heparanase and nm23-H1 in hepatocellular carcinoma显示文摘 | Liu YB Gao SL Chen XP | 2005 | World J Gastroenterol2005，11，9： | 1 |
| 20 | Nitric oxide stimu- lates macrophage inflammatory protein-2 expression in sepsis 显示文摘 | Skidgel RA Gao XP Brovkovych V | 2002 | J Immunol2002，169，4： | 1 |
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