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| 1 | 人类感染新型H7N9禽流感病毒显示文摘2013年4月11日,《新英格兰医学杂志》在线发表了来自中国疾控中心、上海公共卫生临床中心、上海市第五人民医院、上海疾控中心、安徽疾控中心等单位的中国科学家的最新研究成果《人感染新型H7N9禽流感病毒》。介绍了我国科学家发现人感染H7N9禽流感病毒的重要成果和意义. | 李侗曾 Gao RB Cao B Hu YW | 2013 | 北京医学2013,35,6: | 352 |
| 2 | 2019新型冠状病毒基因组特征和流行病学:病毒起源和受体结合的意义显示文摘研究者对来自9例新型冠状病毒肺炎住院患者的支气管肺泡灌洗液样本和培养的分离株进行了下一代测序。从这些个体中获得了严重急性呼吸综合征-冠状病毒2(severe acute respiratory syndrome-coronavirus 2,SARS-CoV-2)的完整和部分基因组序列。利用Sanger测序连接病毒重叠群以获得全长基因组,cDNA末端快速扩增确定终端区。对这些SARSCoV-2基因组和其他冠状病毒基因组进行了系统进化分析,以确定该病毒的进化史并有助于推断其可能的起源。 | 刘青(译) 刘莉(审校) Lu R Zhao X Li J Niu P Yang B Wu H Wang W Song H Huang B Zhu N Bi Y Ma X Zhan F Wang L Hu T Zhou H Hu Z Zhou W Zhao L Chen J Meng Y Wang J Lin Y Yuan J Xie Z Ma J Liu WJ Wang D Xu W Holmes EC Gao GF Wu G Chen W Shi W Tan W | 2020 | 中华高血压杂志2020,28,3: | 516 |
| 3 | Human mesenchymal stem cells overexpressing pigment epitheliumderived factor inhibit hepatocellular carcinoma in nude mice(摘要)显示文摘 | Gao, Y Yao, A Zhang, W Lu, S Yu, Y Deng, L Yin, A Xia, Y Sun, B Wang, X | 2010 | 南京医科大学学报(自然科学版)2010,30,8: | 25 |
| 4 | Zircon SHRIMP U-Pb dating of granites from Dulan and the chronological framework of the North Qaidam UHP belt, NW China显示文摘Zircon SHRIMP dating of granites from Dulan,east segment of North Qaidam UHP belt shows that they are 406.6±3.5 Ma for Yematan-E,407.3±4.3 and 397±6 Ma for Balijiehatan-W,404.5±4.0 and 397.0±3.7 Ma for Shuiwenzhan-N,380.5±5.0 Ma for Shuiwenzhan-S,382.5±3.6 and 372.5±2.8 Ma for Chachagongma.These granites from Dulan represent the products of the third and fourth periods of Paleozoic magmatism in North Qaidam.Geochemically,the granitoids with metalumious to weak peratuminous are quartz diorite,granodiorite,and granite in composition and mainly belong to calc-alkaline series,a few samples to calc or alkali-calc series.The third period of granites is a rock association of granodiorite+granite,with initial 87Sr/86Sr ratios from 0.7082 to 0.7110 and T2DM model ages from 1.41–1.90 Ga;and the fourth period of granites is a rock association of quartz diorite+granodiorite+granite,with initial 87Sr/86Sr ratios from 0.7072 to 0.7091 and T2DM model ages from 1.07–1.38 Ga.Therefore,the third period of granites has higher initial 87Sr/86Sr ratios and T2DM model ages.On the contrary,the fourth period of granites has Nd(t)values from 0.6 to-3.0,higher than that of the third granite with Nd(t)values-3.2 to-9.3.Thus,the data comparison indicates that the third granites may derive from Paleo-proterzoic continental crust with mantle material whereas the fourth granites may derive from the Meso-proterzoic basalt crust with continental material.Combined with regional geology,we thought that the third granites were formed relative to plate exhumation and the fourth granites to delamination of the lithospheric mantle. | WU CaiLai GAO YuanHong LI ZhaoLi LEI Min QIN HaiPeng LI MinZe LIU ChunHua Ronald B FROST Paul T ROBINSON Joseph L WOODEN | 2014 | Science China Earth Sciences2014,57,12: | 21 |
| 5 | Over-expression of heat shock protein 27 attenuates doxorubicin-induced cardiac dysfunction in mice显示文摘 | Liu,L Zhang,X Qian,B Min,XY Gao,X Li,CF Cheng,YL Huang,J | 2007 | 南京医科大学学报(自然科学版)2007,27,11: | 15 |
| 6 | HBx-DNA probe preparation and its application in study of hepatocarcinogenesis显示文摘HBxDNAprobepreparationanditsapplicationinstudyofhepatocarcinogenesisGAOFengGuang,SUNWenSheng,CAOYingLin,ZHANGLiNing,SON... | GAO FengGuang, SUN WenSheng, CAO YingLin, ZHANG LiNing, SONG Jing, LI HuaFen and YAN ShiKunKeywords hepatitis B virus liver neoplasms/etiology carcinoma, hepatocellular/etiology DNA probe | 1998 | World Journal of Gastroenterology1998,4,4: | 12 |
| 7 | Black and green tea consumption and the risk of coronary artery disease, a meta-analysis显示文摘 | Wang ZM Zhou, B Wang, YS Gong, QY Wang, QM Yan, JJ Gao, W Wang, LS | 2011 | 南京医科大学学报(自然科学版)2011,31,4: | 5 |
| 8 | Global distributions of OH and O_2 (1.27 μm) nightglow emissions observed by TIMED satellite显示文摘In order to investigate the global distributions of temporal variations of OH and O2 nightglow emissions,we statistically analyzed their variations with altitude,local time,and season,using the OH and O2 airglow emission rate data observed by the TIMED satellite between 2002 and 2009.The results indicated that the OH nightglow emission was stronger than dayglow emission and the O2 nightglow emission was weaker than dayglow emission.In the tropics,the OH nightglow intensity reached its maximum near midnight;at higher latitudes,the OH nightglow intensities after sunset and before sunrise were much strong.At the equinoxes,the O2 nightglow intensity in the tropics decreased with local time;at the solstices,the local time-latitude distribution of the O2 nightglow intensity had a valley(with weak emission).As for the altitude-latitude distributions of nightglow emission rates,the distribution for OH nightglow at the equinoxes had one peak(with strong emission)at the equator,with a peak height around 85 km;the peak for the March equinox was stronger than that for the September equinox.The distribution for O2 nightglow at the equinoxes had three peaks,lying at 30°in the spring and autumn hemispheres and at the equator,and the peak height at the equator was the lowest.The distributions for both OH and O2 nightglow emissions at the solstices had three peaks.Both nightglow intensities in the tropics had obvious annual and semi-annual variations,the peaks and valleys for semi-annual variations appeared near the equinoxes and solstices,respectively,and the peak at the March equinox was larger than that at the September equinox.The distributions of both OH and O2 nightglow intensities showed a hemispheric asymmetry. | GAO Hong XU JiYao CHEN GuangMing YUAN Wei BELETSKY A. B | 2011 | Science China(Technological Sciences)2011,54,2: | 5 |
| 9 | Common non-synonymous polymorphisms in the BRCA1 Associated RING Domain (BARD1) gene are associated with breast cancer susceptibility:a case-control analysis显示文摘The BRCA1 Associated RING Domain(BARD1) gene has been identified as a high penetrance gene for breast cancer, whose germline and somatic mutations were reported in both non-BRCA1/2 hereditary site-specific and sporadic breast cancer cases. BARD1 plays a crucial role in tumor repression, along with its heterodimeric partner BRCA1. In the current study, we tested the hypothesis that common non-synonymous polymorphisms in BARD1 are associated with breast cancer susceptibility in a case-control study of 507 patients with incident breast cancer and 539 frequency-matched cancer-free controls in Chinese women. We genotyped all three common(minor allele frequency (MAF) > 0.10) non-synonymous polymorphisms(Pro24Ser, Arg378Ser, and Val507Met) in BARD1. We found that the BARD1 Pro24Ser variant genotypes(24Pro/Ser and 24Ser/Ser) and Arg378Ser variant homozygote 378Ser/Ser were associated with a significantly decreased breast cancer risk, compared with their wild-type homozygotes, respectively. Furthermore, a significant locus-locus interaction was evident between Pro24Ser and Arg378Ser (P-int = 0.032). Among the 378Ser variant allele carriers, the 24Pro/Pro wild-type homozygote was associated with a significantly increased breast cancer risk (adjusted OR = 1.81, 95% CI = 1.11-2.95), but the subjects having 24Pro/Ser or Ser/Ser variant genotypes had a significantly decreased risk(adjusted OR = 0.74, 95% CI = 0.56-0.99). In stratified analysis, this locus-locus interaction was more evident among subjects without family cancer history, those with positive estrogen receptor (ER) and individuals with negative progesterone receptor(PR). These findings indicate that the potentially functional polymorphisms Pro24Ser and Arg378Ser in BARD1 may jointly contribute to the susceptibility of breast cancer. | Huo, X Hu, Z. B Zhai, X. J Wang, Y Wang, S Wang, X. C Qin, J. W Chen, W. S Jin, G. F Liu, J. Y Gao, J Wei, Q. Y Wang, X. R Shen, H. B | 2007 | 南京医科大学学报(自然科学版)2007,27,7: | 3 |
| 10 | Application of metamaterials to ultra-thin radar-absorbing material design显示文摘 | Gao Q Yin Y Yan D B | | 0,,17: | 2 |
| 11 | Physica statues solid 显示文摘 | Nan C W Birringer R W Gao H B | 1997 | Applied Research1997,162,: | 2 |
| 12 | Generation of continuous and pulsed diagnostic imaging X-ray radiation using a carbonnanotube based field-emission cathode显示文摘 | YUE G Z QIU Q GAO B | 2002 | Appl Phys Lett2002,181,2: | 2 |
| 13 | Laser patterning for the study of MSC cardiogenic differentiation at the single-cell level显示文摘Mesenchymal stem cells(MSCs)have been cited as contributors to heart repair through cardiogenic differentiation and multiple cellular interactions,including the paracrine effect,cell fusion,and mechanical and electrical couplings.Due to heart–muscle complexity,progress in the development of knowledge concerning the role of MSCs in cardiac repair is heavily based on MSC–cardiomyocyte coculture.In conventional coculture systems,however,the in vivo cardiac muscle structure,in which rod-shaped cells are connected end-to-end,is not sustained;instead,irregularly shaped cells spread randomly,resulting in randomly distributed cell junctions.Consequently,contact-mediated cell–cell interactions(e.g.,the electrical triggering signal and the mechanical contraction wave that propagate through MSC–cardiomyocyte junctions)occur randomly.Thus,the data generated on the beneficial effects of MSCs may be irrelevant to in vivo biological processes.In this study,we explored whether cardiomyocyte alignment,the most important phenotype,is relevant to stem cell cardiogenic differentiation.Here,we report(i)the construction of a laser-patterned,biochip-based,stem cell–cardiomyocyte coculture model with controlled cell alignment;and(ii)single-cell-level data on stem cell cardiogenic differentiation under in vivo-like cardiomyocyte alignment conditions. | Zhen Ma Qiuying Liu Huaxiao Yang Raymond B Runyan Carol A Eisenberg Meifeng Xu Thomas K Borg Roger Markwald Yifei Wang Bruce Z Gao | 2013 | Light(Science & Applications)2013,2,1: | 2 |
| 14 | A high-sensitivity quantitative PCR platform 显示文摘 | DeGraves F J Gao D Kaltenboeck B | 2003 | BioTechniques2003,34,: | 1 |
| 15 | Detection of low observable target within sea clutter by structure function based multifractal analysis显示文摘 | Jing H Wenwen T Gao J B | 2006 | IEEE Transaction on Antennas and Propagation2006,54,1: | 1 |
| 16 | Type I,but not Type Ⅱ,interferon is critical in liver injury induced after ischemia and reperfusion显示文摘 | Zhai Y Qiao B Gao F | 2008 | Hepatology2008,47,: | 1 |
| 17 | Synthesis of nanophase WC powder by a displacement reaction process显示文摘 | Gao L Kear B H | 1997 | Nanostruet Ma- ter1997,9,18: | 1 |
| 18 | Mesh-free numerical simulation for carbon nanotubes upon bending显示文摘 | B GAO Y Z SUN J B WANG | 2010 | Ad- vanced Materials Research2010,139,: | 1 |
| 19 | Adsorption of 2,4,6-trinitrotoluene on a novel adsorption material PEI/SiO2 显示文摘 | An F Gao B J Feng X Q | 2009 | Journal of Hazardous Materials2009,166,23: | 1 |
| 20 | Development of Sn-Zn lead-freesolders bearing alloying elements显示文摘 | Zhang L Xue S B Gao L L | 2010 | Journal of Materials Sci-ence-Materials in Electronics2010,21,1: | 1 |