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| 1 | Gastric endoscopic submucosal dissection:From animal model to patient显示文摘AIM:To assess whether the use of porcine models is useful for learning endoscopic submucosal dissection(ESD),thus contributing to its subsequent application in human patients.METHODS:This study/learning process was carried out in 3 phases:PhaseⅠ:Ex vivo animal;PhaseⅡ:In vivo animal;PhaseⅢ:Humans.One endoscopist performed 30 gastric ESDs in porcine models,and later 5gastric ESDs in 5 patients.The ESD was done following the method practiced at the National Cancer Center in Tokyo,Japan.Technical aspects,size,time and speed of ESD,as well as complications were registered.In patients,their clinical,endoscopic and histologic evolution was additionally added.RESULTS:Thirty en bloc ESDs were carried out in animal models.The mean±SD size of the pieces was of28.4±1.2 mm,and the time of ESD was 41.7±2.4min.The time of ESD in the first 15 procedures was 43.0±3.0 min whereas in the next 15 procedures,the time was 40.3±3.9 min,P=0.588.The speed in the first 15ESDs was 1.25±0.11 cm2/min vs 2.12±0.36 cm2/min in the remaining 15,P=0.028.There were no complications.In patients,5 lesions were resected en bloc.The size of the pieces was 25.2±5.1 mm and the time was85.0±25.6 min.Endoscopic and histological controls did not show evidence of residual neoplastic tissue.CONCLUSION:A sequential ESD training program of a unique endoscopist,based on the practice in porcine models,contributed to learning ESD for its subsequent application in humans,yielding good results in efficacy and safety. | Nicolás González Adolfo Parra-Blanco Miguel Villa-Gómez Alejandra Gamba Andrés Taullard Anaulina Silveira Alberto Sanguinetti Carolina Olano Henry Cohen | 2013 | World Journal of Gastroenterology2013，19，45： | 6 |
| 2 | Neural detection of pipe signatures in ground penetrating radar data显示文摘 | Gamba P Lossani S | 2000 | IEEE Trans on Geo-science and Remote Sensing2000，38，2： | 1 |
| 3 | Dynamics of composite polymerization mediates the development of cuspal strain显示文摘 | Bouillaguet S Gamba J Forchelet J | 2006 | Dent Mater2006，22，10： | 1 |
| 4 | Critical control points for meat balls and kids preparations in a hospital kitchen 显示文摘 | Pedroso D M M laria S T Gamba R C | 1999 | Rev Microbiol1999，30，： | 1 |
| 5 | Multiple genetic origins of histidine-rieh protein 2 gene deletion in Plasmodium falciparum parasites from Peru 显示文摘 | Akinyi S Hayden T Gamba D | 2013 | Sei Rep2013，3，2797： | 1 |
| 6 | Fuzzy shell clustering and pipe detection in ground penetrating radar data显示文摘 | Ciochetto G Delbo S Gamba P | 1999 | IGARSS''991999，，5： | 1 |
| 7 | Factors Influencing Community Residents Participation in Commingled Curbside Recycling Programs显示文摘 | Gamba R J Oskamp S | 1994 | Environment and Behavior1994，26，5： | 1 |
| 8 | Factors influencing communityresidents’ participation in commingled curbside recyclingprograms 显示文摘 | Gamba R J Oskamp S | 1994 | Environment and Behavior1994，26，5： | 1 |
| 9 | Liquid fuels from Fischer-Tropsch wax hydrocracking:Isomer distribution显示文摘 | GAMBA S PELLEGRINI L A CALEMMA V GAMBARO C | | 0，，1： | 1 |
| 10 | Dynamics of composite polymerization mediates the development of cuspal strain显示文摘 | Bouillaguet S Gamba J | 2006 | Dental Materials2006，22，： | 1 |
| 11 | Interleukin-6 and RANTES in Takayasu arteritis: a guide for therapeutic decisions? 显示文摘 | Noris M Daina E Gamba S | 1999 | Circulation1999，100，1： | 1 |
| 12 | Relation of dosing regimen to aminoglycoside ototoxicity:evaluation of auditory damage in the guinea pig显示文摘 | Bamonte F Dionisotti S Gamba M | 1990 | Chemotherapy1990，36，1： | 1 |
| 13 | Factors influencing community residents' participation in commingled curbside recycling programs 显示文摘 | Gamba R J Oskamp S | 1994 | Environment and Behavior1994，26，5： | 1 |
| 14 | Interlukin-6 and RANTES in Takayasu arte- ritis : a guide for therapeutic decisions 显示文摘 | Noris E Daina S Gamba S | 1999 | Circulation1999，100，55： | 1 |
| 15 | Economic analysis of a combined energy-methanol production plant显示文摘 | Pellegrini L A Soave G Gamba S Lange S | 2011 | Applied Energy2011，88，12： | 1 |
| 16 | Robust Extraction of Urban Area Extents in HR and VHR SAR Images显示文摘 | Gamba P Massimilano A Mattia S | 2011 | Selected Topics in Appl Earth Observtions and Remote Sensing2011，4，1： | 1 |
| 17 | Critical control points for meat balls and kibbe preparations in a hospital kitchen 显示文摘 | Pedroso D M M Iaria S T Gamba R C | 1999 | Rev Microbiol1999，30，： | 1 |
| 18 | Energy saving in a CO2 capture plant by MEA scrubbing 显示文摘 | PEELEGRINI L A MOIOLI S GAMBA S | 2011 | Chem Eng Res Des2011，89，9： | 1 |
| 19 | A fuzzy shell clustering approach to recognize hyperbolic signatures in subsurface radar images 显示文摘 | S Delbo P Gamba D Roccato | 2000 | IEEE Trans2000，38，3： | 1 |
| 20 | Evaluation of tissue engineered skinchuman skin substitute and secondary intention healing in the treatment of full thickness wounds after Mohs micrographic or excisional surgery显示文摘 | Gohari S Gamba C Metal H | 2002 | Dematol Surg2002，28，12： | 1 |
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