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| 1 | Management of nonalcoholic fatty liver disease:An evidence-based clinical practice review显示文摘AIM:To build a consensus among Chilean specialists on the appropriate management of patients with nonalcoholic fatty liver disease(NAFLD)in clinical practice.METHODS:NAFLD has now reached epidemic proportions worldwide.The optimal treatment for NAFLD has not been established due to a lack of evidence-based recommendations.An expert panel of members of the Chilean Gastroenterological Society and the Chilean Hepatology Association conducted a structured analysis of the current literature on NAFLD therapy.The quality of the evidence and the level of recommendations supporting each statement were assessed according to the recommendations of the United States Preventive Services Task Force.A modified three-round Delphi technique was used to reach a consensus among the experts.RESULTS:A group of thirteen experts was established.The survey included 17 open-ended questions that were distributed among the experts,who assessed the articles associated with each question.The levels of agreement achieved by the panel were 93.8%in the first round and 100%in the second and third rounds.The final recommendations support the indication of lifestyle changes,including diet and exercise,for all patients with NAFLD.Proven pharmacological therapies include only vitamin E and pioglitazone,which can be used in nondiabetic patients with biopsy-proven nonalcoholic steatohepatitis(the progressive form of NAFLD),although the long-term safety and efficacy of these therapies have not yet been established.CONCLUSION:Current NAFLD management is rapidly evolving,and new pathophysiology-based therapies are expected to be introduced in the near future.All NAFLD patients should be evaluated using a three-focused approach that considers the risks of liver disease,diabetes and cardiovascular events. | Juan P Arab Roberto Candia Rodrigo Zapata Cristián Mu?oz Juan P Arancibia Jaime Poniachik Alejandro Soza Francisco Fuster Javier Brahm Edgar Sanhueza Jorge Contreras M Carolina Cuellar Marco Arrese Arnoldo Riquelme | 2014 | World Journal of Gastroenterology2014，20，34： | 11 |
| 2 | Prognostic factors and time-related changes influence results of colorectal liver metastases surgical treatment:A single-center analysis显示文摘AIM:To analyze the prognostic factors involved in survival and cancer recurrence in patients undergoing surgical treatment for colorectal liver metastases(CLM) and to describe the effects of time-related changes on survival and recurrence in these patients.METHODS:From January 1994 to January 2006,236 patients with CLM underwent surgery with the aim of performing curative resection of neoplastic disease at our institution and 189(80%) of these patients underwent resection of CLM with curative intention.Preoperative,intraoperative and postoperative data,including primary tumor and CLM pathology results,were retrospectively reviewed.Patients were divided into two time periods:a first period from January 1994 to January 2000(n = 93),and a second period from February 2000 to January 2006(n = 143).RESULTS:Global survival at 1,3 and 5 years in patients undergoing hepatic resection was 91%,54% and 47%,respectively.Patients with preoperative extrahepatic disease,carcinoembryonic antigen(CEA) levels over 20 ng/dL,more than four nodules or extrahepatic invasion at pathological analysis had worse survival.Tumor recurrence rate at 1 year was 48.3%,being more frequent in patients with preoperative and pathological extrahepatic disease and CEA levels over 20 ng/dL.Although patients in the second time period had more adverse prognostic factors,no differences in overall survival and recurrence were observed between the two periods.CONCLUSION:Despite advances in surgical technique and better adjuvant treatments and preoperative imaging,careful patient staging and selection is crucial to continue offering a chance of cure to patients with CLM. | Josep Martí María Marta Modolo Josep Fuster Jaume Comas Rebeca Cosa Joana Ferrer Victor Molina Juan Romero Constantino Fondevila Ramón Charco Juan Carlos García-Valdecasas | 2009 | World Journal of Gastroenterology2009，15，21： | 9 |
| 3 | ACC/AHA/ESC更新心房颤动治疗指南显示文摘 | Fuster V Rydén LE Cannom DS 蒋晖(摘译) 蔡琳(校) | 2006 | 心血管病学进展2006，27，6： | 2 |
| 4 | ACC/AHA/ESC 2006 Guidelines for the manage ment of patients with atrial fibrillation:a report of the American College of Cardiology//American heart association task force on practice guidelines and the european society of cardiology committee for practice guidelines (writing committee to revise the 2001 guidelines for the management of patients with atrial fibrillation):developed in collaboration with the European heart rhythm association and the heart rhythm society显示文摘 | Fuster V Rydén L E Cannom D S | 2006 | Circulation2006，114，7： | 1 |
| 5 | ACC/AHA/ESC 2006 Guidelines for the management of patients with atrial fibrillation显示文摘 | Fuster V Rydén LE Cannom DS | 2006 | Circulation2006，114，： | 1 |
| 6 | ACC/AHA/ESC 2006 Guidelines for the management of patients with atrial fibrillation executive summay显示文摘 | Fuster V Rydén LE Cannom DS | 2006 | Circulation2006，114，： | 1 |
| 7 | ACC/AHA/ESC 2006 guidelines for the management of patients with atrial fibrillation:a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the European Society of Cardiology Committee for Practice Guidelines (Writing Committee to Revise the 2001 Guidelines for the Management of Patients With Atrial Fibrillation):developed in collaboration with the European Heart Rhythm Association and the Heart Rhythm Society显示文摘 | Fuster V Rydén LE Cannom DS | 2006 | Circulation2006，114，7： | 1 |
| 8 | Level ground and uphill cycling efficiency in seated and standing positions显示文摘 | Millet GP Tronche C Fuster N | 2002 | Med Sci Sports Exerc2002，34，10： | 1 |
| 9 | ACC/AHA/ESC 2006 guidelines for the management of patients with atrial fibrillation: executive summary: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the European Society of Cardiology Committee for Practice Guidelines and Policy Conferences (Writing Committee to Revise the 2001 Guidelines for the Management of Patients With Atrial Fibrillation ) 显示文摘 | Fuster V Ryd e n LE Cannom DS | 2006 | J Am Coll Cardiol2006，48，： | 1 |
| 10 | ACC/AHA/ESC 2006Guidelines for the Management of Patients with Atrial Fibrillation:a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the European Society of Cardiology Committee for Practice Gu显示文摘 | Fuster V Rydén LE Cannom DS | | 0，，07： | 1 |
| 11 | ACC/AHA/ESC 2006 Guidelines for the the management of patients with atrial fibrillation executive summary显示文摘 | Fuster Ⅴ Rydén LE Cannom DS | 2006 | Circulation2006，114，7： | 1 |
| 12 | Management of patients with atrial fibrillation, a statement for healthcare professionals, from the subcommittee on electrocardiography and electrophysiology, American Heart Association 显示文摘 | PRYSTOWSKY E N BENSON DW J R FUSTER V | 1996 | Circulation1996，93，10： | 1 |
| 13 | Pituitary apoplexy: retrospective study of 9 patients with hypophyseal adenoma 显示文摘 | Carral San laureano F Gavilán Villarejo I Olveira Fuster G | 2001 | An Med Interna2001，18，11： | 1 |
| 14 | ACC/AHA/ESC guidelines for the management of patients with atrial fibrillation显示文摘 | Fuster V Ryde' n LE Asinger RW | 2001 | Eur Heart J2001，22，3： | 1 |
| 15 | Recognizing Global Burden of Cardiovascular Disease and Related Chronic Diseases显示文摘 | Bridget B. Kelly Jagat Narula Valentín Fuster | 2012 | Mt Sinai J Med2012，，6： | 1 |
| 16 | ACC/AHA/ESC 2006 Guidelines for the management of patients with atrial fibrillation显示文摘 | Fuster V Rydén LE Cannom DS | 2006 | Circulation2006，114，7： | 1 |
| 17 | Strontium-89 for palliation of pain from bone metastases in patients with prostate and breast cancer显示文摘 | Francesca Pons Ramón Herranz Alicia Garcia Sergi Vidal-Sicart Carles Conill Juan José Grau Joan Alcover David Fuster Jordi Setoain | 1997 | European Journal of Nuclear Medicine1997，，10： | 1 |
| 18 | ACC/AHA/ESC 2006 guidelines for the management of patients with atrial fibrillation--excutive summary显示文摘 | Fuster V Rydén LE Cannom DS | | 0，，04： | 1 |
| 19 | ACC/AHA/ESC 2006 guidelines for the management of patients with atrial fibrillation executive summary:a report of the American College of Cardiology/American Heart Association Task Force and the European Society of Cardiology Committee for Practice Guidel显示文摘 | Fuster V Rydén LE Cannom DS | | 0，，16： | 1 |
| 20 | ACC/AHA/ESC 2006 guidelines for the management of patients with atrial fibrillation-executive summary:a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the European Society of Cardiology Committee for Practice Guidelines(Writing Committee to Revise the 2001 Guidelines for the Management of Patients with Atrial Fibrillation)显示文摘 | Fuster V Rydén L E Cannom D S | 2006 | Eur Heart J2006，27，： | 1 |
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