|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | DNA methylation in gastric cancer, related to Helicobacter pylori and Epstein-Barr virus显示文摘Gastric cancer is a leading cause of cancer death worldwide,and significant effort has been focused on clarifying the pathology of gastric cancer.In particular,the development of genome-wide analysis tools has enabled the detection of genetic and epigenetic alterations in gastric cancer;for example,aberrant DNA methylation in gene promoter regions is thought to play a crucial role in gastric carcinogenesis.The etiological viewpoint is also essential for the study of gastric cancers,and two distinct pathogens,Helicobacter pylori(H.pylori)and Epstein-Barr virus(EBV),are known to participate in gastric carcinogenesis.Chronic inflammation of the gastric epithelium due to H.pylori infection induces aberrant polyclonal methylation that may lead to an increased risk of gastric cancer.In addition,EBV infection is known to cause extensive methylation,and EBV-positive gastric cancers display a high methylation epigenotype,in which aberrant methylation extends to not only Polycomb repressive complex(PRC)-target genes in embryonic stem cells but also non-PRC-target genes.Here,we review aberrant DNA methylation in gastric cancer and the association between methylation and infection with H.pylori and EBV. | Keisuke Matsusaka Sayaka Funata Masashi Fukayama Atsushi Kaneda | 2014 | World Journal of Gastroenterology2014，20，14： | 12 |
| 2 | Scleral change in experimentally myopic monkeys显示文摘 | Midori Funata Takashi Tokoro | 1990 | Graefe’s Archive for Clinical and Experimental Ophthalmology1990，，2： | 2 |
| 3 | A new clini- copathological entity of IgG4-related autoimmune disease 显示文摘 | Kamisawa T Funata N Hayashi Y | 2003 | J Gastroenterol2003，38，10： | 1 |
| 4 | A new clinicopath- ological entity of IgG4-related autoimmune disease 显示文摘 | Kamisawa T Funata N Hayashi Y | 2003 | J Gas- troenterol2003，38，： | 1 |
| 5 | A new clinicopathologi- cal entity of IgG4 related autoimmune disease显示文摘 | Kamisawa T Funata N Hayashi Y | 2003 | J Gastroenterol2003，38，10： | 1 |
| 6 | A new clinicopathological entity of IgG4-related autoimmune disease 显示文摘 | Kamisawa T Funata N Hayashi Y | 2003 | J Gastroenterol2003，38，10： | 1 |
| 7 | A new clinicopathologi- cal entity of IgG4-related autoimmune disease 显示文摘 | Kamisawa T Funata N Hayashi Y | 2003 | Journal of Gastroenterology2003，38，10： | 1 |
| 8 | Ocular pulse and pulsatile change of scleral strain in living in situ rabbit eyes 显示文摘 | Akazawa Y Tokoro T Funata M | 1994 | Optom Vis Sci1994，71，3： | 1 |
| 9 | A new clinicopathological entity of IgG4-related autoimmune disease显示文摘 | Kamisawa T Funata N Hayashi Y | 2003 | J Gastroenterol2003，38，10： | 1 |
| 10 | Papillary carcinoma of the extrahepatic bile duct: characteristic features and implications in surgical treatment显示文摘 | Atsutake Okamoto Koji Tsuruta Gaku Matsumoto Toshio Takahashi Terumi Kamisawa Naoto Egawa Nobuaki Funata | 2003 | Journal of the American College of Surgeons2003，，3： | 1 |
| 11 | A new clinicopathological entity of IgG4-related autoimmune disease 显示文摘 | Kanaisawa T Funata N Hayashi Y | 2003 | J Gastroenterol2003，38，10： | 1 |
| 12 | A new clinicopathologicalentity of IgG4-related autoimmune disease 显示文摘 | Kamisawa T Funata N Hayashi Y | 2003 | J Gastroenterol2003，38，10： | 1 |
| 13 | Clinicopathologic correlation of a macular hole treated by cortical vitreous peeling and gas tamponade显示文摘 | Madreperla SA Geiger GL Funata M | 1994 | Ophthalmology1994，101，4： | 1 |
| 14 | A new clinicopathological entity of IgG4-related autoimmune disease显示文摘 | Terumi Kamisawa Nobuaki Funata Yukiko Hayashi Yoshinobu Eishi Morio Koike Kouji Tsuruta Atsutake Okamoto Naoto Egawa Hitoshi Nakajima | 2003 | Journal of Gastroenterology2003，，10： | 1 |
| 15 | A new clinicopathological entity o{ IgG4-related autoimmune disease显示文摘 | Kamisawa T Funata N Hayashl Y | 2003 | J Gastroenterol2003，38，10： | 1 |
| 16 | A new clinicopathological entity of IgG4-related autoimmune disease显示文摘 | Kamisawa T Funata N Hayashi Y | 2003 | J Gastroenterol2003，38，： | 1 |
| 17 | A new ehnicopatho- logical entity of IgG4-related autoimmune disease显示文摘 | Kamisawa T Funata N Hayashi Y | 2003 | J Gastroen- terol2003，38，： | 1 |
| 18 | Close relationship between autoimmune pancreatitis and multifocal fibrosclerosis显示文摘 | Kamisawa T Funata N Hayashi Y | 2003 | Gut2003，52，5： | 1 |
| 19 | A new clinicopathological entity of IgG4-related autoimmune disease显示文摘 | Kamisawa T Funata N Hayashi Y | 2003 | J Gastroenterol2003，38，10： | 1 |
| 20 | Pathologic changes in the non-carcinomatous epithelium of the gallbladder in patients with a relatively long common channel 显示文摘 | Kamisawa T Funata N Hayashi Y | 2004 | Gastrointes/ Endosc2004，60，1： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员