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| 1 | Percutaneous cryoablation in combination with ethanol injection for unresectable hepatocellular carcinoma显示文摘AIM: To evaluate the effectiveness and safety of percutaneous hepatic cryoablation in combination with percutaneous ethanol injection (PEI) in patients with unresectable hepaocellular carcinoma (HCC).METHODS: A total of 105 masses in 65 HCC patients underwent percutaneous hepatic cryoablation. The cryoablation was performed with the Cryocare system (Endocare, Irvine, CA, USA) using argon gas as a cryogen.Two freeze-thaw cycles were performed, each reaching a temperature of -180 ℃ at the tip of the probe. PEI was given in 36 patients with tumor masses larger than 6 cm in diameter 1-2 weeks after cryoablation and then once per week for 4 to 6 sessions. The efficacy was evaluated with survival, change of tumor size and alpha-fetoprotein (AFP) levels. RESULTS: During a follow-up duration of 14 months in average with a range of 5 to 21 months, 33 patients (50.8 %)were free of tumors, 22 patients (33.8 %) alive with tumor recurrence: two had bone metastases, three were found to have lung metastases, and the remaining 17 recurrences occurred in the liver, of whom only 3 developed a cryosite recurrence. Among the 41 patients who were followed up for more than one year, 32(78 %) were alive despite of tumor recurrence. Seven patients (10.8 %) died due to disease recurrence. Three patients (4.6 %) died due to some noncancer-related causes. Among the 43 patients who had a CT scan available for review, 38 (88.4 %) had a shrinkage of tumor mass. Among the 22 patients who received biopsies of cryoablated tumor mass, all biopsies except one, showed only dead or scar tissues. Of the patients who had an increased AFP preablatively, 91.3 % had a decrease of AFP to normal or nearly normal levels during postablative 3-6 months. Complications of cryoablation included liver capsular cracking in one patient,transient thrombocytopenia in 4 patients and asymptomatic right-sided pleural effusions in 2 patients. Two patients developed liver abscess at the previous cryoablation site at 2 and 4 months, respectively,following cryoablation, and was recovered after treated with antibiotics and drainage.CONCLUSION: Percutaneous cryoablation offers a safe and possibly curative treatment option for patients with HCC that cannot be surgically removed, and its integration with PEI, may serve as an alternative to partial liver resection in selective patients. | Ke-Cheng Xu Li-Zhi Niu Wei-bin He Zi-Qian Guo Yi-Ze Hu Jian-Sheng Zuo Fuda Cancer Hospital of Guangzhou,Guangzhou 510300,Guangdong Province,China | 2003 | World Journal of Gastroenterology2003，9，12： | 37 |
| 2 | A state-of-the-art review of asphalt pavement surface texture and its measurement techniques显示文摘To understand the research status of asphalt pavement texture,the related achievements and progress of pavement surface texture were systematically sorted out from three aspects:the characterization of pavement surface texture,the texture measurement and evaluation,and the relationship between texture and the skid resistance.Based on the statistical geometric characteristics,the spectral characteristics,the fractal characteristics and the multifractal characteristics,the characteristics of pavement texture were discussed.The test methods of pavement texture were divided into two categories:direct measurement methods and indirect measurement methods.The advantages and disadvantages of each measurement method were summarized.The effects of macro-texture and micro-texture on asphalt pavement were discussed,respectively.The relationship between texture and skid resistance was studied.This review shows that multifractal theory should be further studied from the aspect of road engineering.High-precision non-contact integrated detection technology should be further studied to meet the needs of complex testing environments.The method of finite element numerical simulation has potential for the analysis of pavement skid resistance.In addition,methods such as big data analysis,neural network,and deep learning should be studied to achieve the intelligent perception and management of the whole state of skid resistance prediction. | Siyu Chen Xiyin Liu Haoyuan Luo Jiangmiao Yu Fuda Chen Yang Zhang Tao Ma Xiaoming Huang | 2022 | Journal of Road Engineering2022，2，2： | 3 |
| 3 | Tailoring Nitrogen Terminals on MXene Enables Fast Charging and Stable Cycling Na-Ion Batteries at Low Temperature显示文摘Sodium-ion batteries stand a chance of enabling fast charging ability and long lifespan while operating at low temperature(low-T).However,sluggish kinetics and aggravated dendrites present two major challenges for anodes to achieve the goal at low-T.Herein,we propose an interlayer confined strategy for tailoring nitrogen terminals on Ti_(3)C_(2) MXene(Ti_(3)C_(2)-N_(funct)) to address these issues.The introduction of nitrogen terminals endows Ti_(3)C_(2)-N_(funct) with large interlayer space and charge redistribution,improved conductivity and sufficient adsorption sites for Na^(+),which improves the possibility of Ti_(3)C_(2) for accommodating more Na atoms,further enhancing the Na^(+) storage capability of Ti_(3)C_(2).As revealed,Ti_(3)C_(2)-N_(funct) not only possesses a lower Na-ion diffusion energy barrier and charge trans-fer activation energy,but also exhibits Na^(+)-solvent co-intercalation behavior to circumvent a high de-solvation energy barrier at low-T.Besides,the solid electrolyte interface dominated by inorganic com-pounds is more beneficial for the Na^(+)transfer at the electrode/electrolyte interface.Compared with of the unmodified sample,Ti_(3)C_(2)-Nfunct exhibits a twofold capacity(201 mAh g^(-1)),fast-charging ability(18 min at 80% capacity retention),and great superiority in cycle life(80.9%@5000 cycles)at -25℃.When coupling with Na_(3)V_(2)(PO_(4))_(2)F_(3) cathode,the Ti_(3)C_(2)-N_(funct)//NVPF exhibits high energy density and cycle stability at -25℃. | Yang Xia Lanfang Que Fuda Yu Liang Deng Zhenjin Liang Yunshan Jiang Meiyan Sun Lei Zhao Zhenbo Wang | 2022 | Nano-Micro Letters2022，14，9： | 3 |
| 4 | The basis forresistance to beta-lactam antibiotics by penicillin-binding protein2aof methicillin-resistant Staphylococcus aureus显示文摘 | Fuda C Suvorov M Vakulenko S B | 2004 | J BiolChem2004，279，40： | 1 |
| 5 | Selective separation of β-lactoglobulin from sweet whey using cgas generated from the cationic surfactant CTAB显示文摘 | FUDA E BHATIA D JAUREGI P | 2005 | Biotechnology and Bioengineering2005，90，5： | 1 |
| 6 | Characterization and expres- sion of human bifunctional 3'-phosphoaden0sine 5'-phosphosul- phate synthase isoforms显示文摘 | Fuda H Shimizu C Lee YC | 2002 | Biochem2002，365，： | 1 |
| 7 | Restoration of susceptibility of methicillin-resistant Staphylococcus aureus to beta-lactam antibiotics by acidic pH:role of penicillin-binding protein PImP 2a显示文摘 | Lemaire S Fuda C van Bambeke F | 2008 | J Biol Chem2008，283，12： | 1 |
| 8 | Significance of lymph node sampling in epithelial carcinoma of the ovary显示文摘 | Carnino F Fuda G Ciccone G | 1997 | Gynecol Oncol1997，65，3： | 1 |
| 9 | A peculiar immunoglobulin M (IgM) identified in eggs of chum salmo (On- corhynchus keta) 显示文摘 | FUDA H HARA A YAMAZAKI F | 1992 | Dev Comp Im- munol1992，16，5： | 1 |
| 10 | The basis for resistance to β-lactarn antibiotics by penicillin-binding protein 2a of methiciUin-resistant Staphylococcus aureus 显示文摘 | Fuda C Suvorov M Vakulenko S B | 2004 | J Biol Chem2004，279，40： | 1 |
| 11 | Defining mechanisms that regulate RNA polymerase II transcription in vivo显示文摘 | Fuda N J Ardehali M B Lis I T | 2009 | Nature2009，46，726： | 1 |
| 12 | A peculiar immunoglobulin M (IgM) identified in eggs of chum salmo ( Oncorhynchus keta ) 显示文摘 | Fuda H Hara A Yamazaki F | 1992 | Developmental and Comparative Immunology1992，16，5： | 1 |
| 13 | New V-based alloys with high protium absorption and desorption capacity显示文摘 | Kuriiwa T Tamura T Amemiya T Fuda T Kamegawa A Takamura H Okada M | 1999 | Journal of Alloys and Compounds1999，，： | 1 |
| 14 | Significance of membrane glycoproteins in platelet interaction with oxidized low-density lipoprotein显示文摘 | Takahashi Y Fuda H Yanai H | 1998 | Semin Thromb Hemost1998，24，： | 1 |
| 15 | The basis for resistance to β-1actam antibiotics by penicillin-binding protein 2a of methicillin-resistant Staphylococcus aureus 显示文摘 | Fuda C Suvorov M Vakulenko SB | 2004 | J Biol Chem2004，279，40： | 1 |
| 16 | Acidity distribution of carboxyl groups in Loy Yang browncoal:Its analysis and the change by heat treatment显示文摘 | MURAKAMI Kenji KONDO Ryuhei FUDA Kiyoshi | 2003 | Journalof Colloid and Interface Science2003，260，1： | 1 |
| 17 | Significance of membrane glycoproteins in platelet interaction with high density lipoprotein 显示文摘 | Takahashi Y Fuda H Yanai H | 2004 | Semin Thromb Hemost2004，24，1： | 1 |
| 18 | Significance of lymph node sampiing in epithelial carcinoma of the ovary显示文摘 | Camino F Fuda G Ciccone G | 1997 | Gynecol Oncol1997，65，3： | 1 |
| 19 | A peculiar immunoglobulin M(IgM) identified in eggs of chum salmo(Oncorhynchus keta)显示文摘 | Fuda H Hara A Yamazaki F | 1992 | Dev Comp Immunol1992，16，： | 1 |
| 20 | Protium absorption properties of Ti–V–Cr–Mn alloys with a b.c.c. structure显示文摘 | T Tamura Y Tominaga K Matsumoto T Fuda T Kuriiwa A Kamegawa H Takamura M Okada | 2002 | Journal of Alloys and Compounds2002，，： | 1 |
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