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| 1 | Outcome of Kidney Retransplantation and Associated Factors显示文摘 | Shu Han Youhua Zhu Liming Wang Li Zeng Meisheng Zhou Lei Zhang Shangx Fu | 2009 | 器官移植内科学杂志2009，4，1： | 1 |
| 2 | A Nearly Opti- mal Amplify-and-Forward Relaying Scheme for Two-Hop MIMO Multi-Relay Networks显示文摘 | Fu Youhua Yang Luxi Zhu Wei-Ping | 2010 | IEEE Communications Letters2010，14，3： | 1 |
| 3 | The influence of immunosuppressants on the fertility of males who undergo renal transplantation and on the immune function of their offspring显示文摘 | Longgen Xu Shu Han Yong Liu Hongwei Wang Yirong Yang Feng Qiu Wanling Peng Ligong Tang Jing Fu Xiao-Feng Zhu Xianfan Ding Youhua Zhu | 2009 | Transplant Immunology2009，，： | 1 |
| 4 | Uncertain Comprehensive Evaluation Method Based on Expected Value显示文摘 | Yang Fangfang Fu Youhua | 2014 | Journal of Systems Science and Information2014，2，5： | 1 |
| 5 | An ultrapotent pan-β-coronavirus lineage B(β-CoV-B)neutralizing antibody locks the receptor-binding domain in closed conformation by targeting its conserved epitope显示文摘New threats posed by the emerging circulating variants of SARS-CoV-2 highlight the need to find conserved neutralizing epitopes for therapeutic antibodies and efficient vaccine design.Here,we identified a receptorbinding domain(RBD)-binding antibody,XG014,which potently neutralizesβ-coronavirus lineage B(β-CoV-B),including SARS-CoV-2,its circulating variants,SARSCoV and bat SARSr-CoV WIV1.Interestingly,antibody family members competing with XG014 binding show reduced levels of cross-reactivity and induce antibodydependent SARS-CoV-2 spike(S)protein-mediated cellcell fusion,suggesting a unique mode of recognition by XG014.Structural analyses reveal that XG014 recognizes a conserved epitope outside the ACE2 binding site and completely locks RBD in the non-functional“down”conformation,while its family member XG005 directly competes with ACE2 binding and position the RBD“up”.Single administration of XG014 is effective in protection against and therapy of SARS-CoV-2 infection in vivo.Our findings suggest the potential to develop XG014 as pan-β-CoV-B therapeutics and the importance of the XG014 conserved antigenic epitope for designing broadly protective vaccines againstβ-CoV-B and newly emerging SARS-CoV-2 variants of concern. | Zezhong Liu Wei Xu Zhenguo Chen Wangjun Fu Wuqiang Zhan Yidan Gao Jie Zhou Yunjiao Zhou Jianbo Wu Qian Wang Xiang Zhang Aihua Hao Wei Wu Qianqian Zhang Yaming Li Kaiyue Fan Ruihong Chen Qiaochu Jiang Christian TMayer Till Schoofs Youhua Xie Shibo Jiang Yumei Wen Zhenghong Yuan Kang Wang Lu Lu Lei Sun Qiao Wang | 2022 | Protein & Cell2022，13，9： | 1 |
| 6 | Therapeutic effectiveness of pediatric renal transplantation in 63 cases显示文摘ObjectiveTo 在小儿科的肾的移植探索操作,intra操作治疗和抑制免疫力的药的申请的特征以便改进治疗学的 effectiveness.MethodsFrom 1986年3月到2006年10月,在我们的医院里经历了肾的移植的 63 个孩子的临床的数据是回顾地 analyzed.ResultsThe 1-,3-,5-,10年的接枝幸存率分别地是98.4%,90.5%,88.9%和68.3%。并且相应耐心的幸存率是 100% , 95.2% , 92.1% , 71.4% 。体重增加了 4 ~ 12 kg,身高长大了 2 ~ 6 厘米在第一年期间移植以后。第一年里的主要复杂并发症移植以后是高血压( 26/63 ,41.3%),多毛( 14/63 ,22.2%),导致药的肝的损害( 11/63 ,17.5%),齿龈的增生( 10/63 ,15.8%),肺的感染( 9/63 ,14.3%),骨髓抑制( 5/63 ,7.9%),疱疹( 4/63 ,6.3%)并且糖尿病( 3/63 ,4.8%) .ConclusionRenal 移植是为在结束阶段的孩子的治疗的一个比较喜欢的方法肾的疾病( ESRD )。匹配的好织物,合适的起作用的时间和模式, peri-operactive 照顾对成功,以及适当抑制免疫力的药策略和好依从必要。 | Han Shu Wang Mu Zhu Youhua Zeng Li Zhou Meisheng zhang Lei Fu Shangxi Wang Liming | 2008 | Journal of Medical Colleges of PLA(China)2008，23，1： | 1 |
| 7 | Bioinformatic analysis of human nuclear receptor nr5a2(hb1f) genomic sequence显示文摘We have cloned the cDNA of human nuclear receptor nr5a2(hb1f) gene and obtained its whole genomic sequence previously. In this work we carried out in-depth bioinformatic analysis on the genomic sequence of nr5a2(hb1f) gene. Sequence comparison and prediction algorithms implicated that there might be additional coding regions in the 210 kb genomic sequence besides known exons, especially in the two largest introns. Comparison of the structures of nr5a loci in different species revealed distinguishable conservation and apparent gene duplication during evolution. The remarkable conservation among promoters of zebrafish, mouse and human nr5a2 genes suggested that they would be regulated by the same transcription factors. | Zhang Chengkang Lin Wei Cai Yanning Dong Hui Li Mei Fu Gang Xie Youhua Huang M.Guyang Wang Yuan | 2002 | Chinese Science Bulletin2002，47，7： | 0 |
| 8 | Asymptotic SEP of MIMO beamforming in two-hop AF relaying systems显示文摘This paper derives an asymptotic average symbol error probability(SEP)expression for multiple-input multiple-output(MIMO)two-hop amplify-and-forward(AF)relay systems with optimal beamforming.The analysis at high signal-to-noise ratio(SNR)quantifies the diversity order and array gain,which are valid for any antenna numbers of the terminals and arbitrary channel fading models.It is also proved that the system performance is dominated by the relatively degraded one of the two-hop channels.Our results based on the simple expressions provide valuable insights into the performance and practical design considerations of MIMO AF networks. | FU YouHua HAN YuJie YANG LvXi ZHU WeiPing LIU Chen | 2012 | Science China(Information Sciences)2012，55，2： | 0 |
| 9 | Malignant Tumors of Urinary System in Renal Allograft Recipients: A Report of 12 Cases from One Center显示文摘 | Meisheng Zhou Youhua Zhu Liming Wang Yawei Wang Shangxi Fu Zhilian Ming | 2008 | 器官移植内科学杂志2008，3，2： | 0 |
| 10 | Sequence and Bioinformatics Analysis on MSTN Gene of the Hybrid Grouper Derived from(Epinephelus fuscoguttatus×Epinephelus polyphekadion)显示文摘[Objectives]This study aimed to investigate the sequence structure and function of Myostatin(MSTN)gene in the hybrid grouper(Epinephelus fuscoguttatus,♀×Epinephelus polyphekadion,♂).[Methods]Genetic DNA samples were extracted from the caudal fins of the hybrid grouper and its parents to amplify their MSTN genes.Then,MSTN gene sequences were analyzed using bioinformatics tools to predict their protein structures and functions.[Results]The hybrid grouper and its parents shared the same MSTN gene structure,consisting of three exons and two introns.Nucleotide sequence of the gene could be translated into 376 amino acids,including an N-terminal signal peptide,a proteolytic processing site(RXXR motif),and nine conserved cysteine residues at C-terminal,which were the typical features of transforming growth factor beta(TGF-β)superfamily proteins.Alignment of protein sequence showed that MSTN was highly conserved between the hybrid grouper and its parents.Especially,exon 3,an important functional domain,exhibited a sequence similarity of 100%among them.In addition,four variable amino acid residues were detected in exon 2 at positions 141,153,185 and 186 in the hybrid grouper,but they did not affect the secondary structure of the protein.[Conclusion]These results will provide molecular information for future investigation on the growth and heterosis of hybrid grouper species,and on the roles of MSTN gene in regulating the growth traits of the hybrid grouper. | Liu CAO Pan CEHN Youhua ZHANG Xiaomei FU Hai Huang | 2023 | Agricultural Biotechnology2023，12，3： | 0 |
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