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| 1 | Waste oyster shell as a kind of active filler to treat the combined wastewater at an estuary显示文摘Estuaries have been described as one of the most difcult environments on Earth. It is difcult to know how to treat the combined wastewater in tidal rivers at the estuary, where the situation is very diferent from ordinary fresh water rivers. Waste oyster shell was used as the active filler in this study in a bio-contact oxidation tank to treat the combined wastewater at the Fengtang Tidal River. With a middle-experimental scale of 360 m3/day, the average removal efciency of COD, BOD, NH3-N, TP and TSS was 80.05%, 85.02%,86.59%, 50.58% and 85.32%, respectively, in this bio-contact oxidation process. The living microbes in the biofilms on the waste oyster shell in this bio-contact oxidation tank, which were mainly composed of zoogloea, protozoa and micro-metazoa species, revealed that waste oyster shell as the filler was suitable material for combined wastewater degradation. This treatment method using waste oyster shell as active filler was then applied in a mangrove demonstration area for water quality improvement near the experiment area, with a treatment volume of 5 × 103m3/day. Another project was also successfully applied in a constructed wetland, with a wastewater treatment volume of 1 × 103m3/day. This technology is therefore feasible and can easily be applied on a larger scale. | Hongbing Luo Gu Huang Xiaoying Fu Xiaoling Liu Daocai Zheng Jian Peng Ke Zhang Bo Huang Liangqian Fan Fenghui Chen Xiubo Sun | 2013 | Journal of Environmental Sciences2013，25，10： | 11 |
| 2 | The role of personality,social economic and prevention strategy effects on health-related quality of life among people living with HIV/AIDS显示文摘Background::HIV/AIDS has transformed into a chronic controllable but not yet curable infectious disease as other chronic diseases to some extent.The additional of so called fourth 90%that included the improved health-related quality of life(HRQoL)for people living with HIV(PLWHIV)required solutions beyond antiretroviral therapy and viral load suppression.This study will explore the role of personality,social economic and prevention strategy effection on HRQoL among people living with HIV/AIDS.Methods::A cross-sectional study was conducted among PLWHIV aged more than 16 years old in the 10 municipalities in Yunnan Province,China from October 2019 to May 2020,enrolling total 1997 participants.Individual-level HRQoL data were measured by 12-item Short Form Health Survey(SF-12)and EuroQol Five Dimensions Questionnaire(EQ-5D-5L).We assembled municipal-level data about social economic from Yunnan Statistical Yearbook in 2020 and strategy practice information from the self-evaluation system.We used the principal component analysis to build the social economic and strategy effect on each area respectively and one-way ANOVA was used to perform univariate analysis to identify the predictors with significant differences.Finally we used multi-level model(MLM)to explore the personality,social economic and strategy effects in health-related quality of life among PLWHIV.Results::The global score for quality of life measured using EQ-5D-5L had an estimated mean score(standard deviation,SD)of 0.901±0.146.The HRQoL score measured using PCS-12 had an estimated mean score(SD)of 46.62±8.55.The mean MCS-12 score(SD)was estimated to be 47.80±9.71.The area-level predictors explained a proportion of 13.6-17.2%for the between-area variation of the HRQoL scores,regardless of the total HRQoL,physical component and mental component.The impacts of stigma(P<0.01),social support(P<0.001),anxiety(P<0.001),depression(P<0.05)and social economic status(P<0.05)on HRQoL at the individual-level were significantly different.The plots visualized the impact of individual-level factors on a respondent’s HRQoL was modified by the area-level characteristics.Conclusions::The study identified the possible strategy determinant of individual HRQoL of PLWHIV and also the area effect on HRQoL.Stigma,social support,anxiety,depression and social economic status were the individual-level determinants on HRQoL.These could be a valuable resource for evaluating the overall health of the areas and help improve local decision making. | Xiaowen Wang Hongbing Luo Enlong Yao RenhaiTang Wenbin Dong Fuyong Liu Jun Liang Huilan Li Minyang Xiao Zuyang Zhang Jin Niu Lijun Song Liru Fu Xuehua Li Shicong Qian Qing Guo Zhizhong Song | 2021 | Infectious Diseases of Poverty2021，10，4： | 3 |
| 3 | Bioassay-Guided Extraction of Crude Fucose-Containing Sulphated Polysaccharides from Sargassum fusiforme with Response Surface Methodology显示文摘The response surface methodology(RSM) combined with bioassays was employed to optimize the extraction process of crude fucose-containing sulphated polysaccharides(c FCSP) from Sargassum fusiforme. The central composite design(CCD) was used with four variables, five levels, and four responses. The four variables were p H value of hydrochloric acid solution, extraction temperature(℃), ratio of liquid to raw material(m L g^(-1)), and extraction time(h), respectively. Chemical and bioassay indices were used in combination as the response parameters, which included the yield of c FCSP, fucose content, proliferation rate of spleen cells, and lipopolysaccharide-induced proliferation of splenocytes. The experimental data were fitted to a second-order polynomial equation using multiple regression analysis, and examined using the appropriate statistical methods. The best extraction conditions were as follows: the p H value of hydrochloric acid solution was 3.50; the extraction temperature was 100℃; the ratio of liquid to raw material was 15.00 m L g^(-1) and the extraction time was 2.50 h. The experimental yield was close to the predicted from the model. The extract could promote spleen lymphocyte proliferation, especially the lipopolysaccharide-induced lymphocyte proliferation in vitro, which suggested that its immunomodulatory effect on B lymphocytes. Therefore, c FCSP extracted from S. fusiforme could be utilized as an immunostimulant in functional foods and pharmaceutical industry in future. | FU Zhifei LI Haihua LIU Hongbing HU Shuman LI Yueying WANG Mengxue GUAN Huashi | 2016 | Journal of Ocean University of China2016，15，3： | 2 |
| 4 | Efficient production of pronuclear embryos in breeding and nonbreeding season for generating transgenic sheep overexpressing TLR4显示文摘Background: Brucella is a zoonotic Gram-negative pathogen that causes abortion and infertility in ruminants and humans. TLR4 is the receptor for LPS which can recognize Brucella and initiate antigen-presenting cell activities that affect both innate and adaptive immunity. Consequently, transgenic sheep over-expressing TLR4 are an suitable model to investigate the effects of TLR4 on preventing Brucellosis. In this study, we generated transgenic sheep overexpressing TLR4 and aimed to evaluate the effects of different seasons(breeding and non-breeding season) on superovulation and the imported exogenous gene on growth.Results: In total of 43 donor ewes and 166 recipient ewes in breeding season, 37 donor ewes and 144 recipient ewes in non-breeding season were selected for super-ovulation and injected embryo transfer to generate transgenic sheep.Our results indicated the no. of embryos recovered of donors and the rate of pronuclear embryos did not show any significant difference between breeding and non-breeding seasons(P > 0.05). The positive rate of exogenous TLR4 tested were 21.21 % and 22.58 % in breeding and non-breeding season by Southern blot. The expression level of TLR4 in the transgenic sheep was 1.5 times higher than in the non-transgenic group(P < 0.05). The lambs overexpressing TLR4 had similar growth performance with non-transgenic lambs, and the blood physiological parameters of transgenic and non-transgenic were both in the normal range and did not show any difference.Conclusions: Here we establish an efficient platform for the production of transgenic sheep by the microinjection of pronuclear embryos during the whole year. The over-expression of TLR4 had no adverse effect on the growth of the sheep. | Yan Li Di Lian Shoulong Deng Xiaosheng Zhang Jinlong Zhang Wenting Li Hai Bai Zhixian Wang Hongping Wu Juncai Fu Hongbing Han Jianzhong Feng Guoshi Liu Ling Lian Zhengxing Lian | 2017 | Journal of Animal Science and Biotechnology2017，8，1： | 2 |
| 5 | Experimental study on a hybrid photovoltaic/heat pump system显示文摘 | Chen Hongbing Saffa B R Fu Yu | 2011 | Applied Thermal Engineering2011，31，： | 1 |
| 6 | 显示文摘 | Zhao Yong sheng Fu Hongbing Yao Jiannian | 2008 | Adv Mater2008，20，： | 1 |
| 7 | A study on the antioxidant activity and tissues selective inhibition of lipid peroxi-dation by saponins from the roots of Platycodon grandiflorum显示文摘 | Fu Xianjun Liu Hongbing Wang Peng | 2009 | Am J Chin Ned2009，37，5： | 1 |
| 8 | 17.1%-Efficiency organic photovoltaic cell enabled with two higher-LUMO-level acceptor guests as the quaternary strategy显示文摘Quaternary blended organic solar cells utilize four blended material components(one donor plus three acceptors, two donors and two acceptors, or three donors plus one acceptor) as the active layer materials. The use of four material components allows us to have more material selections and more mechanism choices to improve the photon-to-electron conversion efficiency. In this contribution, we present a new case of quaternary material system, that shows 17.1% efficiency obtained by adding IDIC and PC71BM as the guest acceptors of the host binary of PM6:Y6. The lowest unoccupied molecular orbital(LUMO) levels of IDIC and PC71BM are both higher than that of Y6, which is one reason to obtain increased open-circuit voltage(Voc) in the quaternary device. Upon introduction of IDIC and PC71BM as the acceptor guests, the hole and electron mobilities are both increased, which contributes to the increased short-circuit current-density(Jsc). Effects of the weight ratios of the three acceptor components are investigated, which demonstrates that the increased hole and electron mobilities, the accelerated hole-transfer, and the reduced monomolecular recombination are the factors contributing to the increased Jscand fill-factor. This case of quaternary device demonstrates the applicability of the quaternary strategy in increasing the device functions and hence the efficiencies in the field of organic photovoltaic cells. | Kun Li Yishi Wu Xuemei Li Hongbing Fu Chuanlang Zhan | 2020 | Science China Chemistry2020，63，4： | 1 |
| 9 | Experimental study on a hybrid photovolta ie/heat pump system 显示文摘 | Hongbing Chen Saffa B Riffat Yu Fu | 2011 | Applied Thermal Engineering2011，31，17： | 1 |
| 10 | Analysis of Urbanization Based on Center-of-gravity Movement and Characteristics in Songhua River Basin of China and its Southern Source Sub-basin between 1990 and 2010显示文摘Urbanization in modern times led to a series of development strategies that brought new opportunities in China. Rapid urbanization caused severe stress to the ecosystems and the environment. Using the center-of-gravity(COG) method and parameters such as population, economy, and land, we studied the urbanization pattern in Songhua River Basin and its southern source sub-basin from 1990 to 2010. Urbanization was analyzed based on the COG position, eccentric distance, movement direction of COG, and distance of COG movement. Various characteristics of urbanization in the southern source sub-basin of the Songhua River were explained in relation to the whole Songhua River Basin. Urbanization in the southern source sub-basin of the Songhua River is balanced, relatively advanced, and stable compared to the whole Songhua River Basin. The average eccentric distance between the urbanization COGs in the Songhua River′s south source basin indicated rapid expansion of land urbanization during the span of this study. A basic pattern of urbanization COG in the whole Songhua Basin was observed, but there existed differences among the three aspects of urbanization process. Land urbanization is still in its active stage, so future studies should focus on analysis of such urbanization trends. | FU Xiao SHEN Yuan DONG Rencai DENG Hongbing WU Gang | 2016 | Chinese Geographical Science2016，26，1： | 1 |
| 11 | Nanofibers of 1,3-diphenyl-2-pyrazoline induced by cetyltrimethylammonium bromide micelles显示文摘 | FU Hongbing XIAO Debao YAO Jiannian | 2003 | Angewandte Chemie International Edition2003，42，25： | 1 |
| 12 | Aromaticity Concerto in Polycyclic Conjugated Hydrocarbons:Fusion Pattern on Combined Aromaticity Strategy Leads to Distinctive Excited State Photophysics of Dinaphthopentalenes显示文摘Understanding the structure-property relationships in polycyclic conjugated hydrocarbons(PCHs)is crucial in controlling their electronic properties and developing new optically functional materials.Aromaticity is a fundamentally important and intriguing property of numerous organic chemical structures and has stimulated a myriad of experimental and theoretical investigations.Exploiting aromaticity rules for the rational design of optoelectronic materials with the desired photophysical characteristics is a challenging yet fascinating task.Herein we present an in-depth computational and spectroscopic study on the structure-property relationships of dinaphthopentalenes(DNPs).Results highlight that the different fusion patterns between 4nπand 4n+2πunits endow these PCHs with the tunable aromaticity in the ground state/excited state,which leads to the diverse electronic structures and consequently the distinctive excited state photophysics.Accordingly,we propose a combined aromaticity design strategy for rationally modulating and tailoring electronic and optical properties of PCH skeletons.These outcomes not only present a full picture of the excited state dynamics of the DNP system and afford a new class of efficient singlet fission-active materials but also provide some basic guidelines for exploiting aromaticity rules to design and develop new optical function materials. | Long Wang Lu Lin Teng-Shuo Zhang Shaoting Guo Zuyuan Liu Mengfan Zhang Senhao Wang Ganglong Cui Wei-Hai Fang Jun Zhu Hongbing Fu Jiannian Yao | 2023 | CCS Chemistry2023，5，10： | 0 |
| 13 | Polarity-activated super-resolution imaging probe for the formation and morphology of amyloid fibrils显示文摘The formation of amyloid plaques usually occurs in the early-stage of Alzheimer’s disease(AD).Stimulated emission depletion(STED)imaging provided a powerful tool for visualizing amyloid structures on the nanometer scale.However,many commercial probes adopted in detecting amyloid fibrils are inapplicable to STED imaging,owing to their unmatched absorption and emission wavelengths,small Stokes'shift,easy photo-bleaching,etc.Herein,we demonstrated a polarity-activated STED probe based on an intramolecular charge transfer donor(D)-7c-acceptor(A)compound.The electron-rich carbazole group and the electron-poor pyridinium bromide group,linked by 7i-conjugated thiophen-bridge,ensure strong near infrared(NIR)emission with a Stokes'shift larger than 200 nm.The tiny change in polarity before and after binding with amyloid plaques leads to a transition from weakly emission charge-transfer(CT)state(Φ<0.04)to highly emissive locally-excited(LE)state(Φ=0.57),giving rise to a fluorescence Turn-On probe.Together with large Stokes'shift,good photostability and high depletion efficiency,the super-resolution imaging of the formation and morphology of amyloid fibrils in vitro based on this probe was realized with a lateral spatial resolution better than 33 nm at an extremely low depletion power.Moreover,the ex-vivo super-resolution imaging of(E)-1-butyl-4(2-(5-(9-ethyl-9Hcarbazol-3-yl)thiophen-2-yl)vinyl)pyridinium bromide(CTPB)probe in Aβ plaques in the brain slices of a Tg mouse was demonstrated.This research provides a demonstration of the super resolution imaging probe of amyloid fibrils based on polarity-response mechanism,providing a new approach to the development of future amyloid probes. | Zheng Lv Li Li Zhongwei Man Zhenzhen Xu Hongtu Cui Rui Zhan Qihua He Lemin Zheng Hongbing Fu | 2020 | Nano Research2020，13，9： | 0 |
| 14 | Ultra-long room temperature phosphorescence of indium-based organic inorganic metal halides for naked-eye-visible afterglow显示文摘Solid-state molecules based on room-temperature phosphorescent(RTP)emission have received extensive attention due to their special optical properties of triplet excitons.However,there are still few solid molecular systems with naked-eye-visible afterglow characteristics.Herein,we introduce 4-phenylbenzylamine(namely PBA)with a long conjugated system into common non-toxic In^(3+)to form an indium-based organic inorganic halide,whose chemical formula is PBA_(3)[InCl_6]·H_(2)O.Interestingly,this hybrid halide generates a RTP emission at 617 nm with a lifetime decay as long as 290.4 ms,expressing a naked-eye-visible afterglow for more than 7 s.The mechanism study shows that the long lifetime RTP originated from the specific lamellar stacking of organic molecules and metal halide units,facilitating the interaction between the inorganic layers and organic layers.Therefore,the material can be potentially used in emergency lighting,information security,and other fields.Meanwhile,this work provides a reference for the design and implementation of a more efficient organic-inorganic hybrid system with the ultralong RTP emission. | Heng Yu Hao Gong Zhaorui Hua Yang Zhang Wenming Sun Shuyan Gong Ganglong Cui Yang Tian Hongbing Fu | 2023 | Science China Chemistry2023，66，9： | 0 |
| 15 | Effects of Microbial Fertilizers in Improving Acidic Tobacco-planting Soil and Tobacco Leaf Quality显示文摘[Objectives]This study was conducted to improve acidic soil and enhance the quality of tobacco leaves.[Methods]The effects of different microbial fertilizers on improving acidic tobacco-planting soil and tobacco leaf quality were investigated through plot experiments.[Results]The application of microbial fertilizers could improve the pH value of acidic soil,and composite microbial agent A showed the best application effect.The application of bio-organic fertilizer was beneficial to improving the contents of available phosphorus and available boron in acidic soil.The application of composite microbial agent A was beneficial to improving the contents of available phosphorus and available potassium in acidic soil,and could promote the growth of tobacco plants and improve the economic traits of flue-cured tobacco and the coordination of chemical components in tobacco leaves.The application of composite microbial agent B led to a downward trend in the content of available boron in acidic soil.The application of composite microbial agent B could promote the absorption of nutrients by tobacco plants,and improve their disease resistance and the quality of tobacco leaves.Due to the differences in functional microorganisms contained,the application effects of different microbial fertilizers in improving acidic tobacco-planting soil and improving tobacco leaf quality varied.Overall,the application of microbial fertilizers could increase soil pH,activate soil nutrients,promote tobacco growth,enhance disease resistance,increase tobacco output value,and improve tobacco quality.Microbial fertilizers have good application prospects in improving acidic soil and improving tobacco quality.[Conclusions]The application of microbial fertilizers to improve acidic tobacco-planting soil can ensure the normal growth and development of tobacco plants and the improvement of tobacco leaf quality,achieving high-quality and sustainable development of Zhaotong tobacco. | Xia NI Shungang SHEN Xianyi ZENG Dewen LI Yeming FU Min CHEN Chaokai YU Libing QI Ying-guo RUAN Changchong ZI Haohan GONG Guangjun HU Mengsheng ZHANG Xu ZHANG Shu PENG Hongbing LI | 2023 | Agricultural Biotechnology2023，12，2： | 0 |
| 16 | A Fundamental Study and Applied Exploration of Some Novel Photo-functional Materials显示文摘 | YaoJiannian Fan Meigong Fu Hongbing Ye Cheng Shen Yuquan | 2005 | Bulletin of the Chinese Academy of Sciences2005，19，3： | 0 |
| 17 | Design a thieno[3,2-b]thiophene bridged nonfullerene acceptor to increase open-circuit voltage,short-circuit current-density and fill factor via the ternary strategy显示文摘In this study,we report a new small molecule acceptor(named TT-4 F)which uses 3,6-dimethoxylthieno[3,2-b]thiophene(TT)as theπ-bridge.Addition of 0.05 weight ratio amount of TT-4 F into the host binary blend of PTB7-Th:IEICO-4 F,resulting in a ternary blend in a weight ratio of 1:1:0.05,enables increased open-circuit voltage(Voc),short-circuit curre nt-density(Jsc),and fill-factor(FF)at the same time.Finally,12.1%efficiency is obtained.Compared to the 3-(2-ethylhexyloxylthiophene)bridge on IEICO-4 F,the additional methoxyl group on the TT-6 position is involved in the lowest unoccupied molecular orbital(LUMO)and the largerπ-system on TT increases the electron-donating nature,both of which help to raise the LUMO level,one reason of the increased Voc.Upon addition of 0.05 TT-4 F,the hole mobility is increased,the monomolecular recombination is reduced,and the charge dissociation and collection is enhanced.All of these contribute to the increased Jsc and FF. | Xiaofang Li Kun Li Dan Su Fugang Shen Shuying Huo Hongbing Fu Chuanlang Zhan | 2020 | Chinese Chemical Letters2020，31，5： | 0 |
| 18 | 全基因组关联研究发现中国人群前列腺癌两个新易感位点9q31.2和19q13.4显示文摘0前言在全球范围内,前列腺癌的发病率和病死率存在着巨大差异。该病在西方发达国家发病率最高,在非裔美国人群病死率最高,而在亚洲人群中发病率及病死率均为全球最低,提示不同人种在前列腺癌的遗传方面存在异质性。在欧美和日本人群中,全基因组关联研究(GWAS)技术已经被用于检测前列腺癌的遗传易感性位点,但至今尚无关于GWAS检测中国人群前列腺癌易感位点的报道。 | Jianfeng Xu Zengnan Mo Dingwei Ye Meilin Wang Fang Liu Guangfu Jin Chuanliang Xu Xiang Wang Qiang Shao Zhiwen Chen Zhihua Tao Jun Qi Fangjian Zhou Zhong Wang Yaowen Fu Dalin He Qiang Wei Jianming Guo Denglong Wu Xin Gao Jianlin Yuan Gongxian Wang Yong Xu Guozeng Wang Haijun Yao Pei Dong Yang Jiao Mo Shen Jin Yang Jun Ou-Yang Haowen Jiang Yao Zhu Shancheng Ren Zhengdong Zhang Changjun Yin Xu Gao Bo Dai Zhibin Hu Yajun Yang Qijun Wu Hongyan Chen Peng Peng Ying Zheng Xiaodong Zheng Yongbing Xiang Jirong Long Jian Gong Rong Na Xiaoling Lin Hongjie Yu Sha Tao Junjie Feng Jishan Sun Wennuan Liu Ann Hsing Jianyu Rao Qiang Ding Fredirik Wiklund Henrik Gronberg Xiao-Ou Shu Wei Zheng Hongbing Shen Li Jin Rong Shi Daru Lu Xuejun Zhang Jielin Sun S Lilly Zheng Yinghao Sun | 2013 | 第二军医大学学报2013，34，4： | 0 |
| 19 | Molecular Design Strategy for Practical Singlet Fission Materials:The Charm of Donor/Acceptor Decorated Quinoidal Structure显示文摘Singlet fission(SF)has attracted much attention on account of its great potential for applications in high efficiency solar energy conversion.The major roadblock to realize this potential is rooted in the limited availability of practical SF material with strong absorption,suitable triplet energy level,an efficient SF process,and good chemical stability.Quinoidal structures feature an innate diradical character,which endows these skeletons with SF potential yet results in some structural instability. | Long Wang Xiaomei Shi Shishi Feng WanZhen Liang Hongbing Fu Jiannian Yao | 2022 | CCS Chemistry2022，4，8： | 0 |
| 20 | Efficient triplet pair separation from intramolecular singlet fission in dibenzopentalene derivatives显示文摘In intramolecular SF(iSF), the strong coupling nature and confinement of diffusional separation of ^1(TT) limits the extraction and harnessing of triplet energy. In order to investigate the possible ^1(TT) separation and the role of molecular parameters on it, a series of iSF-capable dibenzopentalene derivatives(DBPs) have been synthesized and their photoinduced dynamics are monitored. iSF takes place in DBPs, accompanied by consecutive ^1(TT) separation in polycrystalline film with almost ^100% yield. It is suggested the strong intermolecular coupling provided by the closely packing configuration in the film facilitates the disentanglement of correlated ^1(TT). Highly efficient triplet pair separation to yield free triplets makes one step forward for utilizing triplet energy from iSF materials for further optoelectronic applications. | Yanping Liu Yishi Wu Long Wang Lanfen Wang Jiannian Yao Hongbing Fu | 2019 | Science China Chemistry2019，62，8： | 0 |
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