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| 1 | 抗癌药的临床前药物试验显示文摘药物筛选是肿瘤化疗的一个重要组成部份,是在50年代初由美国NCI主要依靠动物肿瘤模型发展起来的。新药筛选包括几个阶段:体外试验、体内试验和临床研究。体外试验,系使用动物或人的肿瘤细胞系,观察致死性损伤。如果药物体外有效,则转入体内筛选,主要使用小鼠肿瘤。NCI原来的筛选系统主要使用动物模型,不大依赖于体外试验。 | Sandor Kerpel- Fronius 李学汤 | 1989 | 癌症1989,8,2: | 2 |
| 2 | Predictors and a remedy for noncompliance with amblyopia thera- py in children measured with the occlusion dose moni- tor显示文摘 | Loudon S E Fronius M Looman C W | 2006 | Invest Ophthalmol Vis Sci2006,47,: | 1 |
| 3 | Carbon monoxide rapidly impairs alveolar fluid clearance by inhibiting epithelial sodium channels显示文摘 | MIKE ALTHAUS MARTIN FRONIUS YASMIN BUCH CKERT | 2009 | Am J Res Cell and Mol Bio2009,41,6: | 1 |
| 4 | Visual improvement during psychophysical training in an adult amblyopic eye following visual loss in the contralateral eye显示文摘 | Fronius M Cirina L Cardey A | 2005 | Graefe''s Arch Clin Exp Ophthalmol2005,243,3: | 1 |
| 5 | Preliminary report:monocular spatial localization in children with strabismic amblyopia显示文摘 | Fronius M Sireteanu R Zubcov A 13uttner A | 2000 | Strabismus2000,8,4: | 1 |
| 6 | CMT焊接技术培训资料显示文摘 | Fronius福尼斯 | 2007 | 珠海福尼斯焊接2007,,: | 1 |
| 7 | The role of comparative pharmacokinetics in the planning of human dose escalation: the experience with diacetyldianhydrogalactitol显示文摘 | Kerpel - Fronius S Erdelyi - Toth V Somfai - Relle S | 1988 | Cancer Chemother Pharmacol1988,22,2: | 1 |
| 8 | Some aspects of the cur- rent controversy about the treatment of amblyopia显示文摘 | Fronius M | 2002 | Ophthalmologe2002,99,10: | 1 |
| 9 | An XPS study of the passivating oxide layer produced on GaAs (001) substrate by heating in air above 200 ℃ 显示文摘 | CONTOUR J P MASSIES J FRONIUS H | 1988 | Jpn J Appl Phys1988,27,2: | 1 |
| 10 | Ion transport by pulmonary epithelia显示文摘 | Hollenhorst MI Richter K Fronius M | 2011 | J Biomed Biotechnol2011,,17: | 1 |
| 11 | Predictors and a remedy for noncompliance with amblyopia therapy in children measured with the occlusion dose monitor显示文摘 | Loudon SE Fronius M Looman CW | | 0,,10: | 1 |
| 12 | Amiloride-sensitive sodiumchannels and pulmonary edema显示文摘 | Althaus M Clauss WG Fronius M | 2011 | PulmMed2011,2011,83: | 1 |
| 13 | Training the adult amblyopie eye with 'Perceptual Learning' after vision loss in the non-amblyopic eye 显示文摘 | Fronius M Cirina L Kuhli C | 2006 | Strabismus2006,14,2: | 1 |
| 14 | Carbon mon- oxide rapidly impairs alveolar fluid clearance by inhibiting epithelial sodium channels显示文摘 | Althaus M Fronius M Buch-Ckert Y | 2009 | Am J Respir Cell Mol Biol2009,41,6: | 1 |
| 15 | Ion trans- port by pulmonary epithelia显示文摘 | HOLLENHORST MI RICHTER K FRONIUS M | 2011 | J Biomed Biotechnoh2011,2011,17: | 1 |
| 16 | 斜视手术和遮盖疗法后斜视性弱视的患儿对视物变形的适应——遮盖疗法与视物变形显示文摘Background: Reduced visual acuity and deficient binocularity are well-known symptoms of amblyopia. Distortions of visual space perception were reportedmore recently in strabismic amblyopia. This study investigated whether strabismus surgery and occlusion therapy have an influence on these deficits in amblyopic children. Materials and Methods: Two aspects of vertical alignment of amblyopic eyes,namely spatial distortion and spatial uncertainty,were investigated prospectively in 13 children (mean age 6 years 9 months) before and after strabismus surgery and in 12 children (mean age 6 years 11 months) during 6 months of occlusion therapy. Results: A different impact of the two types of therapeutic intervention was observed: a slight (statistically not significant) increase of uncertainty was the only change noticed postoperatively after 1 week,spatial distortions were not affected. During occlusion treatment,both clear shifts of alignment and a decrease of uncertainty occurred. Conclusions: The geometry of visual space of amblyopic children showed modifications due to altered visual experience during treatment,most obviously during occlusion therapy. These changes are evidence for unknown features of plasticity of the amblyopic visual system initiated by treatment. | Fronius M. 王永强(译) | 2006 | 世界核心医学期刊文摘(眼科学分册)2006,2,6: | 0 |
| 17 | 临床药理学与抗癌药物的发展显示文摘抗癌药的发展需进行一系列筛选、实验、临床前药理和临床试用过程。当某种新药经临床前药理等研究被证明具有一定治疗作用,并且对人体无严重毒副作用时,该新药便可被投入临床试用。临床试用包括临床药理学、临床疗效观察和临床使用价值的评价三个阶段。在临床药理学阶段(即第一期临床试用阶段),通过药代动力学、药效学(时/效关系、量/ | Sandor Kerpel- Fronius 刘云英 | 1989 | 癌症1989,8,2: | 0 |
| 18 | 伏能士分享汽车焊接解决方案显示文摘2016年8月25日下午,全球领先的焊机制造商伏能士(Fronius)在第十二届上海国际汽车制造技术与装备及材料展览会(AMTS2016)期间举办了第二期“伏能士汽车焊接解决方案分享会”。据悉,伏能士自2015年起按年度举办该会议,分享汽车制造领域中的焊接案例以及新型材料和高难度焊接的经验,为从事汽车焊接实践的客户提供有价值的解决方案参考,受到业内一致好评。 | Fronius | 2016 | 汽车工艺师2016,0,10: | 0 |
| 19 | 斜视性弱视儿童空间定位的缺陷 | Fronius M. Sireteanu R. Zubcov A. 齐翔云 | 2005 | 世界核心医学期刊文摘(眼科学分册)2005,0,4: | 0 |