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34篇 您的检索式:作者名="Frederic T"
    题名 作者 年代 出处 被引量
1The relationship of the Manifest Con- tent of Dreams to Duration of Childbirth in Primiparae 显示文摘Carolyn W Frederic T 1972Psychosomatic Medicine1972,34,:1
2Electroantennogram responses of Douglas-fir seed chalcids to plant volatiles显示文摘Denis T Frederic M P 1998J Insect Physiol1998,44,56:1
3Involvement of toll-like receptor 5 in mouse model of colonic hypersensitivity induced by neonatal maternal separation显示文摘BACKGROUND Chronic abdominal pain is the most common cause for gastroenterology consultation and is frequently associated with functional gastrointestinal disorders including irritable bowel syndrome and inflammatory bowel disease. These disorders present similar brain/gut/microbiota trialogue alterations, associated with abnormal intestinal permeability, intestinal dysbiosis and colonic hypersensitivity(CHS). Intestinal dysbiosis can alter colon homeostasis leading to abnormal activation of the innate immunity that promotes CHS, perhaps involving the toll-like receptors(TLRs), which play a central role in innate immunity.AIM To understand the mechanisms between early life event paradigm on intestinal permeability, fecal microbiota composition and CHS development in mice with TLRs expression in colonocytes.METHODS Maternal separation model(NMS) CHS model, which mimics deleterious events in childhood that can induce a wide range of chronic disorders during adulthood were used. Colonic sensitivity of NMS mice was evaluated by colorectal distension(CRD) coupled with intracolonic pressure variation(IPV) measurement. Fecal microbiota composition was analyzed by 16S rRNA sequencing from weaning to CRD periods. TLR mRNA expression was evaluated in colonocytes.Additionally, the effect of acute intrarectal instillation of the TLR5 agonist flagellin(FliC) on CHS in adult naive wildtype mice was analyzed.RESULTS Around 50% of NMS mice exhibited increased intestinal permeability and CHS associated with intestinal dysbiosis, characterized by a significant decrease of species richness, an alteration of the core fecal microbiota and a specific increased relative abundance of flagellated bacteria. Only TLR5mRNA expression was increased in colonocytes of NMS mice with CHS. Acute intrarectal instillation of FliC induced transient increase of IPV, reflecting transient CHS appearance.CONCLUSION Altogether, these data suggest a pathophysiological continuum between intestinal dysbiosis and CHS, with a role for TLR5.Geoffroy Mallaret Amandine Lashermes Mathieu Meleine Ludivine Boudieu Julie Barbier Youssef Aissouni Agathe Gelot Benoit Chassaing Andrew T Gewirtz Denis Ardid Frederic Antonio Carvalho 2022World Journal of Gastroenterology2022,28,29:1
4BMI-lgene amplification and overexpression in hematological malignancies occur mainly in mantle cell lymphomas显示文摘 Frederic T Magda P 2001Cancer Res2001,61,6:1
5In vitro spermicidal activity of peptides from amphibian skin:Dermaseptin S4 and derivatives显示文摘Amira Z Catherine S Frederic T 2011Bioorganic & Medicinal Chemistry2011,16,:1
6Expression of human -defensin-1,-2, and -3 in non-in{lamed pseudocyst, mu- coceles显示文摘MK Frederic T Yamaai N Mizukawa 2008Oral Diseases2008,14,:1
7A Practical Archi-tecture for Reliable Quantum Computers显示文摘 Frederic T C Isaac C 2002IEEE Computer2002,1,:1
8Benign abnormalities andcarcinoid tumors of the central airway显示文摘Gilbert R Frederic T Jean-Luc B 0,,05:1
9The Measurement of Physical Fitness as a Problem in Physical Medicine显示文摘J JUNG FREDERIC T 1951Arch Phys Med1951,32,:1
10Population toxicokinet- its of benzene 显示文摘Frederic Y B Elise T J Kaija Pekari 1996Environmental Health Perspectives1996,104,6:1
11Isolation of plant-growth-promoting Bacillus strains from soybean root nodules显示文摘Yu M B Frederic D A Smith D L Brian T D 2002Can J Microbiol2002,48,:1
12Intraocular pressure during a very high altitude climb显示文摘Martina MB Daniel B Tobias MM Frederic T 0,,03:1
13The CLUSTAL_ X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools 显示文摘Julie D T Toby J G Frederic P Francois J Desmond G H 1997Nucleic Acids Research1997,25,:1
14Serum-free large-scale transient transfection of CliO cells显示文摘Madiha D Philippe G Frederic V T 2004Biotechnology and Bioengineering2004,87,4:1
15Field emission properties of multiwalled carbon nanotubes显示文摘Bonard J M Frederic M Stoeckli T 1998Ultramicroscopy1998,73,:1
16Annealing- free solution-processed tungsten oxide for inverted organic solar cells显示文摘Frederic G Dimitris T George S 2014Solar Energy Materials and Solar Cells2014,122,:1
17Electroinitiated polymerization of maleic an hydride显示文摘Frederic C S Alane E T 1986Macromolecules1986,19,5:1
18Whitening efficacy of plant extracts including orchid extracts on Japanese female skin with melisma and lenfigosenilis显示文摘TAKETSUGU T FREDERIC B JEAN C 2010Journal of Dermatology2010,37,:1
19Accretion in strong field gravity with eXTP显示文摘In this paper we describe the potential of the enhanced X-ray Timing and Polarimetry(eXTP) mission for studies related to accretion flows in the strong field gravity regime around both stellar-mass and supermassive black-holes. eXTP has the unique capability of using advanced 'spectral-timing-polarimetry' techniques to analyze the rapid variations with three orthogonal diagnostics of the flow and its geometry, yielding unprecedented insight into the inner accreting regions, the effects of strong field gravity on the material within them and the powerful outflows which are driven by the accretion process.Alessandra De Rosa Phil Uttley LiJun Gou Yuan Liu Cosimo Bambi Didier Barret Tomaso Belloni Emanuele Berti Stefano Bianchi Ilaria Caiazzo Piergiorgio Casella Marco Feroci Valeria Ferrari Leonardo Gualtieri Jeremy Heyl Adam Ingram Vladimir Karas FangJun Lu Bin Luo Giorgio Matt Sara Motta Joseph Neilsen Paolo Pani Andrea Santangelo XinWen Shu JunFeng Wang Jian-Min Wang YongQuan Xue YuPeng Xu WeiMin Yuan YeFei Yuan Shuang-Nan Zhang Shu Zhang Ivan Agudo Lorenzo Amati Nils Andersson Cristina Baglio Pavel Bakala Altan Baykal Sudip Bhattacharyya Ignazio Bombaci NiccolóBucciantini Fiamma Capitanio Riccardo Ciolfi Wei K.Cui Filippo D'Ammando Thomas Dauser Melania Del Santo Barbara De Marco Tiziana Di Salvo Chris Done Michal Dovciak Andrew C.Fabian Maurizio Falanga Angelo Francesco Gambino Bruce Gendre Victoria Grinberg Alexander Heger Jeroen Homan Rosario Iaria JiaChen Jiang ChiChuan Jin Elmar Koerding Manu Linares Zhu Liu Thomas J.Maccarone Julien Malzac Antonios Manousakis Frédéric Marin Andea Marinucci Missagh Mehdipour Mariano Méndez Simone Migliari Cole Miller Giovanni Miniutti Emanuele Nardini Paul T.O'Brien Julian P.Osborne Pierre Olivier Petrucci Andrea Possenti Alessandro Riggio Jerome Rodriguez Andrea Sanna LiJing Shao Malgosia Sobolewska Eva Sramkova Abigail L.Stevens Holger Stiele Giulia Stratta Zdenek Stuchlik Jiri Svoboda Fabrizio Tamburini Thomas M.Tauris Francesco Tombesi Gabriel Torok Martin Urbanec Frederic Vincent QingWen Wu Feng Yuan Jean J.M.in't Zand Andrzej A.Zdziarski XinLin Zhou 2019Science China(Physics,Mechanics & Astronomy)2019,62,2:1
20Vibrations measurements with a self-mixing type laser displacement aensor for modal analysis显示文摘BOSCH T SERVAGENT N FREDERIC S B 1996IEEE Instrumentation and Measurement Technology Conference Brussels1996,1,2:1
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