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| 1 | Levels of insecticide resistance to deltamethrin,malathion,and temephos,and associated mechanisms in Aedes aegypti mosquitoes from the Guadeloupe and Saint Martin islands(French West Indies)显示文摘Background:In the Guadeloupe and Saint Martin islands,Aedes aegypti mosquitoes are the only recognized vectors of dengue,chikungunya,and Zika viruses.For around 40 years,malathion was used as a mosquito adulticide and temephos as a larvicide.Since the European Union banned the use of these two insecticide molecules in the first decade of the 21st century,deltamethrin and Bacillus thuringiensis var.israelensis are the remaining adulticide and larvicide,respectively,used in Guadeloupe.In order to improve the management of vector control activities in Guadeloupe and Saint Martin,we investigated Ae.aegypti resistance to and mechanisms associated with deltamethrin,malathion,and temephos.Methods:Ae.aegypti mosquitoes were collected from six different localities of Guadeloupe and Saint Martin.Larvae were used for malathion and temephos bioassays,and adult mosquitoes for deltamethrin bioassays,following World Health Organization recommendations.Knockdown resistance(Kdr)genotyping for V1016I and F1534C mutations,and expression levels of eight enzymes involved in detoxification mechanisms were examined in comparison with the susceptible reference Bora Bora strain.Results:Resistance ratios(RR50)calculated for Ae.aegypti larvae showed high resistance levels to temephos(from 8.9 to 33.1-fold)and low resistance levels to malathion(from 1.7 to 4.4-fold).Adult females displayed moderate resistance levels to deltamethrin regarding the time necessary to affect 50%of individuals,varying from 8.0 to 28.1-fold.Molecular investigations on adult mosquitoes showed high resistant allele frequencies for V1016I and F1534C(from 85 to 96%and from 90 to 98%,respectively),as well as an overexpression of the glutathione S-transferase gene,GSTe2,the carboxylesterase CCEae3a,and the cytochrome genes 014614,CYP6BB2,CYP6M11,and CYP9J23.Conclusions:Ae.aegypti populations from Guadeloupe and Saint Martin exhibit multiple resistance to organophosphates(temephos and malathion),and pyrethroids(deltamethrin).The mechanisms associated with these resistance patterns show strong frequencies of F1534C and V1016I Kdr mutations,and an over-expression of CCEae3a,GSTe2,and four cytochrome P450 genes(014614,CYP9J23,CYP6M11,CYP6BB2).These results will form the baseline for a deeper understanding of the insecticide resistance levels and associated mechanisms of Ae.aegypti populations and will be used to improve vector control strategies in Guadeloupe and Saint Martin. | Daniella Goindin Christelle Delannay Andric Gelasse Cedric Ramdini Thierry Gaude Frederic Faucon Jean-Philippe David Joël Gustave Anubis Vega-Rua Florence Fouque | 2017 | Infectious Diseases of Poverty2017，6，1： | 3 |
| 2 | Computer-based land use suitability mapping显示文摘 | John L Frederic P S | 1983 | The Cartographic Journal1983，10，2： | 2 |
| 3 | Structural characterization of the extrocellular polysaccharides produced by Streptococcus thermophilus SFi39 and SFi12 显示文摘 | JEROME L FREDERIC C JEAN-MICHEL W | 1997 | Applied and Environmental Microbiology1997，63，： | 1 |
| 4 | Porosity reduction in sandstone by quartzes growth显示文摘 | Frederic L Won C P | 1986 | AAPG Bulletin1986，70，11： | 1 |
| 5 | Porosity reduction in sandstone by quartz over growth 显示文摘 | Frederic L Won C P | 1986 | AAPG Bu|letin1986，70，11： | 1 |
| 6 | Venetian Shipping During the Commercial Revolution显示文摘 | FREDERIC C L | 1993 | The American Historical Review1993，，2： | 1 |
| 7 | The cold-inducible RNA-binding protein migrates from the nucleus to cytoplasmic stress granules by a methyl- ation-dependent mechanism,acts as a translational represr显示文摘 | Frederic D L Tong Z Corinne W | 2007 | Experimental Cell Research2007，313，20： | 1 |
| 8 | Breast cancer in preg- nancy显示文摘 | Frederic A Sibylle L Patrick N | 2012 | Lancet2012，379，： | 1 |
| 9 | Comprehensive modeling of mat density effect on duckweed (Lenma minor) growth under controlled eutrophication 显示文摘 | FREDERIC M SAMIR L LOUISE M | 2006 | Water Research2006，40，15： | 1 |
| 10 | Radiation-force technique to monitor lesions during ultrasonic therapy显示文摘 | Frederic L Lizzl Muratore R | 2003 | Ultrasound in Medicine & Biology2003，29，11： | 1 |
| 11 | Impairment of mycobacterial immunity in human interleukin-12 receptor deficiency显示文摘 | Frederic A Anne D David L | 1998 | Science1998，280，： | 1 |
| 12 | Measurement of phthalates diesters in food using gas chromatography-tandem mass spectrometry显示文摘 | RONAN C FREDERIC L FABRICE M | 2016 | Food Chem2016，196，： | 1 |
| 13 | Purification and characterization of cassiicolin,the toxin produced by Corynespora cassiicola,causal agent of the leaf fall disease of rubber tree显示文摘 | Frederic de L Marie-Pierre D Christine S | 2007 | Journal of Chromatography B2007，849，： | 1 |
| 14 | The Presence of salt and a curing agent reduces bacteriocin production by Lactobacillus sakei CTC494, a potential starter cultrue for sausage fermentation显示文摘 | Frederic L Lucde V | 1999 | Appl Environ Microbiol1999，65，12： | 1 |
| 15 | A Tabu Search Heuristic for lhe Undirected Selective Traveling Salesman Problem 显示文摘 | Ichel G Gilbert L Frederic S | 1998 | European J of Operational1998，106，1： | 1 |
| 16 | Growth of the bacterioicn-producing Lactobacillus sakei strain CTC 494 in MRS borth is strongly reduced due to nutrient exhaustion: a nutrient depletion model for the growth of lactic acid bacteria显示文摘 | Frederic L De V L | 2001 | Appl Enviro Microbiol2001，67，10： | 1 |
| 17 | Prediction of the temperature field in fiat plate heat pipes with micro-grooves - Experimental validation 显示文摘 | Frederic L Romuald R Guillaume P | 2008 | International Journal of Heat and Mass Transfer2008，51，： | 1 |
| 18 | Arbitrary dispersion control of ultrashort optical pulses with acoustic waves显示文摘 | Frederic V Vincent L Huignard J P | 2000 | J Opt Soc Am B2000，17，： | 1 |
| 19 | IFN-γ-receptor deficiency in an infant with fatal bacille calmette-guerin infection显示文摘 | Emmanuelle J Frederic A Salma L | 1996 | N Engl J Med1996，335，26： | 1 |
| 20 | Humanin binds and nullifiesbid activity by blocking its activation of bax and bak 显示文摘 | Dayong Z Frederic L Xiuwen Z | 2005 | J Biol Chem2005，280，： | 1 |
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