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| 1 | Epidemiology and natural history of hepatitis C virus infection显示文摘Hepatitis C virus(HCV)affects 130-210 million people worldwide and is one of the major risk factors for hepatocellular carcinoma.Globally,at least one third of hepatocellular carcinoma cases are attributed to HCV infection,and 350000 people died from HCV related diseases per year.There is a great geographical variation of HCV infection globally,with risk factors for the HCV infection differing in various countries.The progression of chronic hepatitis C to end-stage liver disease also varies in different study populations.A long-term follow-up cohort enrolling participants with asymptomatic HCV infection is essential for elucidating the natural history of HCV-caused hepatocellular carcinoma,and for exploring potential seromarkers that have high predictability for risk of hepatocellular carcinoma.However,prospective cohorts comprising individuals with HCV infection are still uncommon.The risk evaluation of viral load elevation and associated liver disease/cancer in HCV(REVEAL-HCV)study has followed a cohort of 1095 residents seropositive for antibodies against hepatitis C virus living in seven townships in Taiwan for more than fifteen years.Most of them have acquired HCV infection through iatrogenic transmission routes.As the participants in the REVEALHCV study rarely receive antiviral therapies,it provides a unique opportunity to study the natural history of chronic HCV infection.In this review,the prevalence,risk factors and natural history of HCV infection are comprehensively reviewed.The study cohort,data collection,and findings on liver disease progression of the REVEAL-HCV study are described. | Mei-Hsuan Lee Hwai-I Yang Yong Yuan Gilbert L’Italien Chien-Jen Chen | 2014 | World Journal of Gastroenterology2014，20，28： | 14 |
| 2 | Oxytocin infusion during second stage of labor in primiparous women using epidural analgesia: a randomized double blind placebo-controlled trial显示文摘 | Spiby H Gilbert L | 1989 | Br Med J1989，299，6713： | 1 |
| 3 | Public organization and Rural marketing planning in England and Wales显示文摘 | GILBERT D TUNG L | 2001 | Applied Geography2001，21，： | 1 |
| 4 | Physico - chemical treatment echniques for wastewater laden with heavy metals 显示文摘 | Kumiawan T A Gilbert Y S Wai H L | 2006 | Chemical Engineering Journal2006，118，12： | 1 |
| 5 | An Examination of Organizational Trust Antecedents 显示文摘 | GILBERT J A TANG T L | 1998 | Public Personnel Management1998，27，3： | 1 |
| 6 | A study of biologically active peptide sequences (P-15) on the surface of an ABM scaffold (PepGen P-15TM) using AFM and FTIR显示文摘 | HOLE B B SCHWARZ J A GILBERT J L | 2005 | J Biomed Mater Res A2005，74，4： | 1 |
| 7 | Using ESEM and SEM to compare the performance of dentin conditioners显示文摘 | Gilbert L C Doherty R E | 1993 | Microscopy Research and Technique1993，25，56： | 1 |
| 8 | Gold and trace element zonation in pyrite using a laser imaging technique: Implications for the timing of gold in orogenic and Carlin- style sediment- hosted deposits 显示文摘 | R R Large L Danyushevsky C Hollit V Maslennikov S Meffer S Gilbert S Bull R Scott P Emsbo H Thomas B Singh J Foster | 2009 | Economic Geology2009，104，5： | 1 |
| 9 | Determinants of portfolio performance Ⅱ: An update 显示文摘 | BRINSON G P SINGER B D GILBERT L BEE- BOWER G L | 1991 | Financial Analysis Journal1991，47，3： | 1 |
| 10 | Fracture toughness and fatigue-crack propagation in a Zr-Ti-Cu-Ni-Be bulk metallic glass显示文摘 | Gilbert C J Ritchie M R O Johnson W L | 1997 | Appl Phys Lett1997，71，4： | 1 |
| 11 | Pharmacodynamics of ziprasidone in children and adolescents: impact on dopamine transmission 显示文摘 | Sallee FR Gilbert DL Vinks AA Miceli JJ Robarge L Wilner K | 2003 | J Am Acad Child Adolesc Psychiatry2003，42，8： | 1 |
| 12 | Characteristics of infants with severe retinopathy of prematurity in countries with low,moderate, and high levels of development: implications for screening programs 显示文摘 | Gilbert C Fielder A GordiUo L | 2005 | Pediatrics2005，115，5： | 1 |
| 13 | CD4 ( +)T-cell ac-tivation and induction of autoimmune hepatitis following trichloroethylene treatment in MRL + 1+ mice显示文摘 | Griffin J M Gilbert K M Lamps L W | 2000 | Toxicol Sci2000，57，2： | 1 |
| 14 | Sex ratio variations as a function of host size in Pseudacteon flies(Diptera,Phoridae),parasitoids of Solenopsis fire ants(Hymenoptera,Formicidae)显示文摘 | Morrison L W Porter S D Gilbert L E | 1999 | Biol J Linn Soc1999，66，： | 1 |
| 15 | The potential of IGF-1 and TGF beta1 for promoting 'adult' articular cartilage repair: an in vitro study 显示文摘 | Davies L C Blain E J Gilbert S J | 2008 | Tissue Eng Part A2008，14，7： | 1 |
| 16 | The degrada- tion of arginine by Clostridium perfringens (BP6K) 显示文摘 | GILBERT C S MILAN A L ALFRED A T | 1952 | Journal of Biological Chemisty1952，198，2： | 1 |
| 17 | Effects of a couple based intervention to reduce risks for HIV, HCV, and STIs among drug-involved heterosexual couples in Kazakb- stan: A randomized controlled trial 显示文摘 | E1 Bassel N Gilbert L Terlikbayeva A etal | 2014 | J Acquit Immune DeficSyndr2014，67，2： | 1 |
| 18 | Suspended clay and the population dynamics of planktonic rotifers and cladocerans显示文摘 | KIRK K L GILBERT J J | 1990 | Ecology1990，71，： | 1 |
| 19 | Higher rates of autism and attention deficit/hyperactivity disorder in American children:Are food quality issues impacting epigenetic inheritance?显示文摘In the United States,schools offer special education services to children who are diagnosed with a learning or neurodevelopmental disorder and have difficulty meeting their learning goals.Pediatricians may play a key role in helping children access special education services.The number of children ages 6-21 in the United States receiving special education services increased 10.4%from 2006 to 2021.Children receiving special education services under the autism category increased 242%during the same period.The demand for special education services for children under the developmental delay and other health impaired categories increased by 184%and 83%respectively.Although student enrollment in American schools has remained stable since 2006,the percentage distribution of children receiving special education services nearly tripled for the autism category and quadrupled for the developmental delay category by 2021.Allowable heavy metal residues remain persistent in the American food supply due to food ingredient manufacturing processes.Numerous clinical trial data indicate heavy metal exposures and poor diet are the primary epigenetic factors responsible for the autism and attention deficit hyperactivity disorder epidemics.Dietary heavy metal exposures,especially inorganic mercury and lead may impact gene behavior across generations.In 2021,the United States Congress found heavy metal residues problematic in the American food supply but took no legislative action.Mandatory health warning labels on select foods may be the only way to reduce dietary heavy metal exposures and improve child learning across generations. | Renee J Dufault Raquel A Crider Richard C Deth Roseanne Schnoll Steven G Gilbert Walter J Lukiw Amanda L Hitt | 2023 | World Journal of Clinical Pediatrics2023，12，2： | 1 |
| 20 | Fifty Years of Vehicle Routing 显示文摘 | Gilbert L | 2009 | Transportation Science2009，43，4： | 1 |
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