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| 1 | A 10-miRNA risk score-based prediction model for pathological complete response to neoadjuvant chemotherapy in hormone receptor-positive breast cancer显示文摘Patients with hormone receptor(HR)-positive tumors breast cancer usually experience a relatively low pathological complete response(p CR)to neoadjuvant chemotherapy(NAC).Here,we derived a 10-micro RNA risk score(10-mi RNA RS)-based model with better performance in the prediction of p CR and validated its relation with the disease-free survival(DFS)in 755 HRpositive breast cancer patients(273,265,and 217 in the training,internal,and external validation sets,respectively).This model,presented as a nomogram,included four parameters:the 10-mi RNA RS found in our previous study,progesterone receptor(PR),human epidermal growth factor receptor 2(HER2)status,and volume transfer constant(K).Favorable calibration and discrimination of 10-mi RNA RS-based model with areas under the curve(AUC)of 0.865,0.811,and 0.804 were shown in the training,internal,and external validation sets,respectively.Patients who have higher nomogram score(>92.2)with NAC treatment would have longer DFS(hazard ratio=0.57;95%CI:0.39–0.83;P=0.004).In summary,our data showed the 10-mi RNA RS-based model could precisely identify more patients who can attain p CR to NAC,which may help clinicians formulate the personalized initial treatment strategy and consequently achieves better clinical prognosis for patients with HRpositive breast cancer. | Chang Gong Ziliang Cheng Yaping Yang Jun Shen Yingying Zhu Li Ling Wanyi Lin Zhigang Yu Zhihua Li Weige Tan Chushan Zheng Wenbo Zheng Jiajie Zhong Xiang Zhang Yunjie Zeng Qiang Liu RStephanie Huang Andrzej LKomorowski Eddy SYang François Bertucci Francesco Ricci Armando Orlandi Gianluca Franceschini Kazuaki Takabe Suzanne Klimberg Naohiro Ishii Angela Toss Mona PTan Mathew A Cherian Erwei Song | 2022 | Science China(Life Sciences)2022，65，11： | 3 |
| 2 | Skin erythrodiapedesis during chronic venous disorders 显示文摘 | Caggiati A Franceschini M Heyn R | 2011 | J Vasc Surg2011，53，6： | 1 |
| 3 | Quantitative evaluation of induction motor broken bars by means of electrical signature analysis显示文摘 | Bellini A Filippetti F Franceschini G | 2001 | 1EEE Transactions on Industry Applications2001，37，5： | 1 |
| 4 | Quantitative evaluation of induction motor broken bars by means of electrical signature analysis 显示文摘 | Bellini A Filippetti F Franceschini G | 2001 | IEEE Transactions on Industrial Applition2001，37，5： | 1 |
| 5 | On-field experience with online diagnosis of large induction motors cage failures using MCSA显示文摘 | Bellini A Filippetti F Franceschini G | 2002 | IEEE Transactions on Industry Applications2002，38，4： | 1 |
| 6 | In vitro activity of antimycotic agents determined by E-test method agaist vaginal candidia species显示文摘 | Candido R C Toloi M R Franceschini S A | 1998 | Mycopathologia1998，144，1： | 1 |
| 7 | Characterization of spatial and temporal variations in the optical proper ties of tissuelike media with diffuse reflectance imaging 显示文摘 | FABBRI F FRANCESCHINI M A FANTINI S | 2003 | Appl Opt2003，42，16： | 1 |
| 8 | Low-affinity NGF-receptor and E-N-CAM expression define two types of olfactory nerve ensheathing cells that share a common lineage显示文摘 | Barnett S C | 1996 | Dev Biol1996，173，： | 1 |
| 9 | STRING vl0 : protein-protein interaction networks, in- tegrated over the tree of life 显示文摘 | Szklarczyk D Franceschini A Wyder S | 2015 | Nucleic Acids Re- search2015，43，： | 1 |
| 10 | The STRING database in 2011: functional interaction networks of pro- teins, globally integrated and scored显示文摘 | Szklarczyk D Franceschini A Kuhn M | 2011 | Nucleic Acids Res2011，26，39： | 1 |
| 11 | Use of the robot assisted gait therapy in rehabilitation of patients with stroke and spinal cord injury显示文摘 | Sale P Franceschini M Waldner A | 2012 | Eur J Phys Rehabil Med2012，48，1： | 1 |
| 12 | Quantitative Evaluation of Induction Motor Broken Bars By Means of Electric Signals Signatures显示文摘 | Bellini A Filippetti F Franceschini G | 2001 | IEEE Transactions on Industry Applications Society2001，37，5： | 1 |
| 13 | Risk of congenitalcomplete heart block in newborns of mothers with anti-RO/SSA antibodies detected by counterimmunoelectro-phoresis:aprospective study of 100 women显示文摘 | Brucato A Frassi M Franceschini F | 2001 | ArthritisRheum2001，44，8： | 1 |
| 14 | Effect of aerobic train-ing on walking capacity and maximal exercise tolerance in patientswith multiple sclerosis:A randomized crossover controlled study显示文摘 | Rampello A Franceschini M Piepoli M | 2007 | Phys Ther2007，87，5： | 1 |
| 15 | Battery choiceand management for new-generation electric vehicles显示文摘 | Affanni A Bellini A Franceschini G | 2005 | IEEE Transactions on Industrial Electronics2005，52，5： | 1 |
| 16 | Developmental pattern of expression of the alpha chemokine stromal cell-derived factor 1 in the rat central nervous system显示文摘 | Tham T N Lazarini F Franceschini I A | 2001 | Eur J Neurosci2001，13，： | 1 |
| 17 | On the measurement of the high rate flow properties of organo-clay platelet filled polyamide 6 melts by capillary rheometer 显示文摘 | BALDI F FRANCESCHINI A BIGNOTH F | 2011 | Polym Test2011，30，7： | 1 |
| 18 | Skin erythrodiapedesis during chronic venous disorders显示文摘 | Caggiati A Franceschini M Heyn R | 2011 | J Vasc Surg2011，53，6： | 1 |
| 19 | Battery choice and management for new generation electric vehicles显示文摘 | AFFANNI A BELLINI A FRANCESCHINI G | 2005 | IEEE Transactions on Industrial Electronics2005，52，5： | 1 |
| 20 | STRING vl0: pro- tein-protein interaction networks, integrated over the tree of life 显示文摘 | Szklarczyk D Franceschini A Wyder S | 2015 | Nucleic Acids Res2015，43，： | 1 |
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