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| 1 | 解淀粉芽孢杆菌NS2降解玉米赤霉烯酮的研究显示文摘为了丰富玉米赤霉烯酮(ZEN)解毒菌种库,通过采集湖南省邵阳市等7个省市粮食样品,筛选获得1株能够高效降解ZEN的解淀粉芽孢杆菌NS2。采用高效液相色谱法检测降解前后ZEN的含量发现,液态发酵72 h,该菌对5 mg·L-1 ZEN标准品的降解率高达96.0%,固态发酵72 h,菌株对玉米粉中2.5 mg·L-1 ZEN标准品的降解率高达88.2%。采用高效液相色谱与四级杆飞行时间质谱联用技术检测该菌处理后的ZEN降解产物,未检测出具有毒性作用的α-玉米赤霉烯醇(α-ZOL)、β-玉米赤霉烯醇(β-ZOL)等ZEN的类似物。此外,抗菌活性试验与木聚糖酶、纤维素酶和蛋白酶活性试验显示降解菌NS2还能通过产生具有抗菌作用的次生代谢产物,抑制病原微生物大肠杆菌和鼠伤寒沙门氏菌的生长。上述结果表明,解淀粉芽孢杆菌NS2可以高效降解ZEN,具有潜在应用前景,为ZEN解毒产品的开发与应用奠定了材料基础。 | 张晨曦 Yawa Minnie Elodie Folly 赵月菊 刘阳 | 2020 | 核农学报2020，，7： | 7 |
| 2 | Estimation of Time to Maximum Rate Under Adiabatic Conditions(TMR_(ad)) Using Kinetic Parameters Derived From DSC-Investigation of Thermal Behavior of 3-Methyl-4-Nitrophenol显示文摘Kinetic parameters of the decomposition of hazardous chemicals can be applied for the estimation of their thermal behavior under any temperature profile.Presented paper describes the application of the advanced kinetic approach for the determination of the thermal behavior also under adiabatic conditions occurring e.g.in batch reactors in case of cooling failure.The kinetics of the decomposition of different samples(different manufacturers and batches) of 3-methyl-4-nitrophenol were investigated by conventional DSC in non-isothermal(few heating rates varying from 0.25 to 8.0K/min) and isothermal(range of 200~260℃) modes.The kinetic parameters obtained with AKTS-Thermokinetics Software were applied for calculating reaction rate and progress under different heating rates and temperatures and verified by comparing simulated and experimental signals.After application of the heat balance to compare the amount of heat generated during reaction and its removal from the system,the knowledge of reaction rate at any temperature profiles allowed the determination of the temperature increase due to the self-heating in adiabatic and pseudo-adiabatic conditions.Applied advanced kinetic approach allowed simulation the course of the Heat-Wait-Search(HWS) mode of operation of adiabatic calorimeters.The thermal safety diagram depicting dependence of Time to Maximum Rate(TMR) on the initial temperature was calculated and compared with the results of HWS experiments carried out in the system with Ф-factor amounting to 3.2.The influence of the Ф-factor and reaction progress reached at the end of the HWS monitoring on the TMR is discussed.Presented calculations clearly indicate that even very minor reaction progress reduces the TMRad of 24h characteristic for a sample with initial reaction progress amounting to zero.Described estimation method can be verified by just one HWS-ARC,or by one correctly chosen ISO-ARC run of reasonable duration by knowing in advance the dependence of the TMR on the initial temperature for any Ф-factor.Proposed procedure results in significant shortening of the measuring time compared to a safety hazard approach based on series of ARC experiments carried out at the beginning of a process safety evaluation. | Bertrand Roduit Patrick Folly Alexandre Sarbach Beat Berger Franz Brogli Francesco Mascarello Mischa Schwaninger Thomas Glarner Eberhard Irle Fritz Tobler Jacques Wiss Markus Luginbühl Craig Williams Pierre Reuse Francis Stoessel | 2011 | 化学推进剂与高分子材料2011，9，1： | 3 |
| 3 | Different Patterns of Recurrence in Gastric Cancer Depending on Lauren’s Histological Type: Longitudinal Study显示文摘 | Daniele Marrelli Franco Roviello Giovanni de Manzoni Paolo Morgagni Alberto Di Leo Luca Saragoni Alfonso De Stefano Secondo Folli Claudio Cordiano Enrico Pinto | 2002 | World Journal of Surgery2002，，9： | 2 |
| 4 | Laparoscopic gastric banding prevents type 2 diabetes and arterial hypertension and induces their remission in morbid obesity:a 4-year case-controlled study显示文摘 | Pontiroli AE Folli F Paganelli M | 2005 | Diabetes Care2005，28，11： | 1 |
| 5 | Interaction between leptin and insulin signaling pathways differentially affects JAK-STAT and PI 3-kinase-mediated signaling in rat liver 显示文摘 | Carvalheira JB Ribeiro EB Folli F | 2003 | Biol Chem2003，384，1： | 1 |
| 6 | Intrinsic protein flexibility in regulation of cell proliferation: advantages for signaling and opportu- nities for novel therapeutics 显示文摘 | Follis AV Galea CA Kriwacki RW | 2012 | Adv Exp Med Biol2012，725，： | 1 |
| 7 | Early gastric cancer:prognostic factors in 223 Patients显示文摘 | Follis S Dente M Dell Amori D | 1995 | Br J surg1995，82，： | 1 |
| 8 | Long-term beneficial effect of islet transplantation on diabetic macro-/microangiopathy in type 1 diabetic kidney-transplanted patients显示文摘 | Fiorina P Folli F Bertuzzi F | | 0，，： | 1 |
| 9 | High rate of posi- tive anti-tissue transglutaminase antibodies in chronic liver dis- ease, Role of liver decompensafion and of the antigen source显示文摘 | VECCHI M FOLLI C DONATO MF | 2003 | Scand J Gastroenterol2003，38，1： | 1 |
| 10 | Autoantibodies to GAB -ergic neurons and Pancreatic beta cells in still- man syndrome显示文摘 | Solimena M Folli F | 1990 | N Engl J Med1990，322，： | 1 |
| 11 | Ti O2photocatalysis in cementitious systems:Insights into self-cleaning and depollution chemistry显示文摘 | Folli A Pade C Hansen T B | 2012 | Cement and Concrete Research2012，42，3： | 1 |
| 12 | Risk factors for lymph node metastasis and their prognostic significance in early gastric cancer(EGC) fur the Italian Research Group for Gastric Cancer( IRGGC ) 显示文摘 | Folli S Morgagni P Roviello F | 2001 | J Clin Oncol2001，31，10： | 1 |
| 13 | Autoantibodies to GABA- ergic neurons and pancreatic beta cells in stiff-man syndrome显示文摘 | Solimena M Folli F Aparisi R | 1990 | N Engl J Med1990，322，22： | 1 |
| 14 | Risk factors for lymph node metastases and their prognostic significance in early gastric cancer (EGC) for the Italian Research Group for Gastric Cancer (IRGGC)显示文摘 | Folli S Morgagni P Roviello F | 2001 | Jpn J Clin Oncol2001，31，10： | 1 |
| 15 | Potential use of exenatide for the treat- ment of obesity 显示文摘 | Folli F Guardado Mendoza R | 2011 | Expert Opin Investig Drugs2011，20，12： | 1 |
| 16 | Effectiveness of postinoculation(R)-9-(2-phosphonylmethoxypropyl)adenine treatment for prevention of persistent simian immunodeficiency virus SIVmne infection depends critically on timing of initiation and duration of treatment显示文摘 | Tsai CC Emau P Follis KE | 1998 | J Virol1998，72，5： | 1 |
| 17 | Cerebral-umbilical Doppler ratio as a predictor of adverse perinatal outcome显示文摘 | Gramellini D Folli MC Raboni S | 1992 | Obstet Gynecol1992，79，3： | 1 |
| 18 | Angiotensin Ⅱ inhibits insulin signaling in aortic smooth muscle cells at multiple levels: a potential role for serine phosphorylation in insulin/angiotensin Ⅱ crosstalk显示文摘 | Folli F Kahn CR Hansen H | 1997 | J Clin Invest1997，100，9： | 1 |
| 19 | Insulin receptor substrate -1 (IRS-1) distribution in the rat central nervous system显示文摘 | Folli F Bonfanti L Renard E | 1994 | J Neurosci1994，14，11： | 1 |
| 20 | An alternative repair technique for anastomotic leakage after total gastrectomy显示文摘 | Folli S Morgagni P Bazzocchi F | 2000 | J Am Coll Surg2000，190，6： | 1 |
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