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13篇 您的检索式:作者名="Folci"
    题名 作者 年代 出处 被引量
1The epigenetics of autoimmunity显示文摘The etiology of autoimmune diseases remains largely unknown.Concordance rates in monozygotic twins are lower than 50% while genome-wide association studies propose numerous significant associations representing only a minority of patients.These lines of evidence strongly support other complementary mechanisms involved in the regulation of genes expression ultimately causing overt autoimmunity.Alterations in the post-translational modification of histones and DNA methylation are the two major epigenetic mechanisms that may potentially cause a breakdown of immune tolerance and the perpetuation of autoimmune diseases.In recent years,several studies both in clinical settings and experimental models proposed that the epigenome may hold the key to a better understanding of autoimmunity initiation and perpetuation.More specifically,data support the impact of epigenetic changes in systemic lupus erythematosus,rheumatoid arthritis,multiple sclerosis and other autoimmune diseases,in some cases based on mechanistical observations.We herein discuss what we currently know and what we expect will come in the next future.Ultimately,epigenetic treatments already being used in oncology may soon prove beneficial also in autoimmune diseases.Francesca Meda Marco Folci Andrea Baccarelli Carlo Selmi 2011Cellular & Molecular Immunology2011,8,3:8
2AMPAR trafficking in synapse maturation and plasticity显示文摘Bassani S Folci A Zapata J 2013Cell Mol Life Sci2013,70,23:1
3AMPAR trafficking in synapse maturation and plasticity 显示文摘Bassani S Folci A Zapata J 2013Cell Mol Life Sci2013,70,23:1
4AMPAR trafficking in syn- apse maturation and plasticity 显示文摘Bassani S Folci A Zapata J 2013Cell Mol Life Sci2013,70,23:1
5Clinical and echocardiogramphic disease in patirnts starting end-stage renal disease therapy显示文摘Folcy RN Parfrcy PS Harnett JD 2002Kidney Int2002,22,:1
6AMPAR trafficking in synapse maturation and plasticity显示文摘Bassani S Folci A Zapata J 2013Cell Mol Life Sci2013,70,23:1
7The epigenetics of autoimmunity显示文摘Meda F Folci M Baccarelli A 0,,03:1
8Removal of iron oxides from bauxite ores显示文摘FOLCY E TITTLE K 1971Inst Mining Met Proc1971,239,:1
9Land-Use choiees:Balaneing human needs and ecosystem function显示文摘Ruth S DeFiles Jonathan A Folcy Gregory PAsner 2004Front Ecol Environ2004,2,5:1
10Clinical and echocardiogramphic disease in patimts starting end ·stage renal disease therapy显示文摘Folcy RN Pafrcy PS Harnett JD 2002Kidney Int2002,22,:1
11Clinical epidemiology of cardiovascular dis- ease in chronic renal disease显示文摘Folcy RN Parfiey PS Samak MJ 1998Am J Kidney Dis1998,32,53:1
12Airway nitric oxide output is reduced in bronchiectasis显示文摘Folcy SC Hopkins NO Fitzgerald MX 0,,07:1
13AMPAR trafficking in synapse maturation and plasticity显示文摘Bassani S Folci A Zapata J 2013Cell Mol Life Sci2013,70,23:1
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