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| 1 | CPC, a Single-Repeat R3 MYB, Is a Negative Regulator of Anthocyanin Biosynthesis in Arabidopsis显示文摘象 CPC (突变) 一样的单个重复的 R3 MYB 抄写因素被知道在象根头发区别和毛状体开始那样的发展过程起作用。然而,任何一个都没六个 Arabidopsis 单个重复的 R3 MYB 成员被报导调整 flavonoid 生合成。我们这里证明 CPC 是 anthocyanin 生合成的一个否定管理者。在使用 CPC 测试 GAL4 依赖的司机线的过程,我们在调停 GAL4 的 CPC overexpression 之上观察了 anthocyanin 合成的压抑。我们证明因为更多的根头发,这不由于滋养的举起的增加。更确切地说, CPC 表达式水平紧控制 anthocyanin 累积。整个染色体上的 Microarray 分析显示出那, 37 ? 测试的 000 个特征, 85 基因被镇压比大由 CPC overexpression 三方面。这 85,七是迟了的 anthocyanin 生合成基因。另外, anthocyanin 合成基因被显示在 35S::CPC overexpression 植物下面调整。短暂表示结果建议 CPC 与 R2R3MYB 抄写因素 PAP1/2 竞争,它是 anthocyanin 生合成基因的使活跃之物。这份报告把 anthocyanin 生合成加到在 CPC 控制下面的节目的集合,显示这个管理者为发展节目不仅(例如根头发,毛状体) ,但是罐头影响 anthocyanin 颜料合成。 | Hui-Fen Zhu Karen Fitzsimmons Abha Khandelwal Robert G. Kranz | 2009 | Molecular Plant2009，2，4： | 34 |
| 2 | Epstein-Barr virus and Burkitt lymphoma显示文摘In 1964,a new herpesvirus,Epstein-Barr virus(EBV),was discovered in cultured tumor cells derived from a Burkitt lymphoma(BL)biopsy taken from an African patient.This was a momentous event that reinvigorated research into viruses as a possible cause of human cancers.Subsequent studies demonstrated that EBV was a potent growth-transforming agent for primary B cells,and that all cases of BL carried characteristic chromosomal translocations resulting in constitutive activation of the c-MYC oncogene.These results hinted at simple oncogenic mechanisms that would make Burkitt lymphoma paradigmatic for cancers with viral etiology.In reality,the pathogenesis of this tumor is rather complicated with regard to both the contribution of the virus and the involvement of cellular oncogenes.Here,we review the current understanding of the roles of EBV and c-MYC in the pathogenesis of BL and the implications for new therapeutic strategies to treat this lymphoma. | Martin Rowe Leah Fitzsimmons Andrew I Bell | 2014 | Chinese Journal of Cancer2014，33，12： | 14 |
| 3 | Statin therapy is associated with fewer deaths in patients with bacteraemia显示文摘 | Peter Kruger Kenneth Fitzsimmons David Cook Mark Jones Graeme Nimmo | 2006 | Intensive Care Medicine2006，，1： | 2 |
| 4 | To clot or not to clot? That is the question in central venous catheters显示文摘 | Cadman A Lawrance J A Fitzsimmons L | 2004 | Clin Radiol2004，59，4： | 1 |
| 5 | Evaluation of brewer's waste as partial replacement of fish meal protein in Nile tilapia, Oreochromis niloticus, diets显示文摘 | Zerai D B Fitzsimmons K M Collier R J | 2008 | J World Aquacult Soc2008，39，4： | 1 |
| 6 | Strategies for globalizing service operations 显示文摘 | McLaughlin C P Fitzsimmons J A | 1996 | International Journal of Service Industry1996，7，4： | 1 |
| 7 | Maternal inheritance of seed weight in flax显示文摘 | Smith W E Fitzsimmons J E | 1965 | Can J Gene Cytol1965，，7： | 1 |
| 8 | Nonclinical and early clinical development of tacrolimus ointment for the treatment of atopic dermatitis 显示文摘 | Bekersky I Fitzsimmons W Tanase A | 2001 | J Am Acad Dematol2001，44，1： | 1 |
| 9 | Combined mag netic fields increase insulin-lide,growth factor2 in TE-85 hu- man osteosarcona bone cell cultures显示文摘 | Fitzsimmons R J Ryaby J T Mohen S | 1995 | Endocrimo1995，136，7： | 1 |
| 10 | Radiocapitellar sta- bility :the effect of soft tissue integrity on bipolar versus monopolar radial head prostheses显示文摘 | Chaulalit C Shukla DR Fitzsimmons JS et M | 2011 | J Shoulder Elbow Surg2011，20，2： | 1 |
| 11 | 1 The role of periosteum in cartilage repair显示文摘 | Shawn W J ames S Fitzsimmons BS | 2001 | Clin Ort ho Res2001，，： | 1 |
| 12 | Statin therapy is associated with fewer deaths in patients with bacteraemia显示文摘 | Kruger P Fitzsimmons K Cook D | 2006 | Intensive Care Med2006，32，1： | 1 |
| 13 | The set of real numbers left uncovered by random covering intervals显示文摘 | P. J. Fitzsimmons Bert Fristedt L. A. Shepp | 1985 | Zeitschrift für Wahrscheinlichkeitstheorie und verwandte Gebiete1985，，2： | 1 |
| 14 | Halo- phytes for the treatment of saline aquaculture efflu- ent显示文摘 | Brown J Glenn E P Fitzsimmons K M | 1999 | Aquaculture1999，175，3： | 1 |
| 15 | IGF-Ⅱ receptor number is in-creased in TE-85 osteosarcoma cells by combined magnetic fields显示文摘 | Fitzsimmons R J Ryaby F P Magee F P | 1995 | J Bone miner Res1995，10，5： | 1 |
| 16 | Identification of purebred Crocodylus siomensis for reintroduction in Vietnam显示文摘 | Fitzsimmons N N Buchan J Lam P V | 2002 | Journal of Experimental Zoology2002，294，： | 1 |
| 17 | Geographic structure of mitochondrial and nuclear gene polymorphisms in australian green turtle population and male-biased gene flow显示文摘 | FitzSimmons N N Moritz C Limpus C J | 1997 | Genetics1997，147，4： | 1 |
| 18 | Long term clinical and angiographic outcomes with the Wingspan stent fortreatment of symptomatic 50% - 99% intracranial atherosclerosis : single center experience in 51 cases 显示文摘 | Wolfe TJ Fitzsimmons BF Hussain SI | 2009 | J Neurointerv Surg2009，1，1： | 1 |
| 19 | Immunoreactive eythropoietin concentrations in fetal and neonatal rats and the effects of hypoxia显示文摘 | Clemons G K Fitzsimmons S L Demanincor D | 1986 | Blood1986，68，： | 1 |
| 20 | Tissue engineer- ing of cartilage using poly-epsilon-eaprolaetone nanofiher scaf- folds seeded in vivo with periosteal cells 显示文摘 | ME Casper JS Fitzsimmons JJ Stone | 2010 | Osteoarthritis and Cartilage2010，18，7： | 1 |
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