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| 1 | Prognostic criteria for postoperative mortality in 170 patients undergoing major right hepatectomy显示文摘BACKGROUND: Postoperative hepatic failure is a dreadful complication after major hepatectomy and carries high morbidity and mortality rates. In this study, we assessed the accuracy of the 50/50 criteria (bilirubin >2.9 mg/dL and international normalized ratio >1.7 on postoperative day 5) and the Mullen criteria (bilirubin peak >7 mg/dL on postoperative days 1-7) in predicting death from hepatic failure in patients undergoing right hepatectomy only. In addition, we identified prognostic factors linked to intra-hospital morbidity and mortality in these patients. METHODS: One hundred seventy consecutive patients underwent major right hepatectomy at a tertiary medical center from 2000 to 2008. Nineteen (11.2%) patients suffered from liver cirrhosis. Univariate and multivariate analyses were performed to identify predictors of intra-hospital mortality, morbidity and death from hepatic failure. RESULTS: The intra-hospital mortality was 6.5% (11/170). Of the six patients who died from hepatic failure, one was positive for the 50/50 criteria, but all six patients were positive for the Mullen criteria. Multivariate analysis showed that male gender, hepatitis C (HCV), hepatocellular carcinoma, postoperative bilirubin >7 mg/dL and ALT<188 U/L on postoperative day 1 were predictive of death from hepatic failure in the postoperative period. Age >65 years, HCV, reoperation, andrenal failure were significant predictors of overall intra-hospital mortality on multivariate analysis. CONCLUSIONS: The Mullen criteria were more accurate than the 50/50 criteria in predicting death from hepatic failure in patients undergoing right hepatectomy. A bilirubin peak >7 mg/dL in the postoperative period, HCV positivity, hepatocellular carcinoma, and an ALT level <188 U/L on postoperative day 1 were associated with death from hepatic failure in our patient population. | Filippo Filicori Xavier M Keutgen Matteo Zanello Giorgio Ercolani Salomone Di Saverio Federico Sacchetti Antonio Daniele Pinna Gian Luca Grazi | 2012 | Hepatobiliary & Pancreatic Diseases International2012，11，5： | 2 |
| 2 | A panel of four miRNAs accurately differentiates malignant from benign indeterminate thyroid lesions on fine needle aspiration显示文摘 | Keutgen XM Filicori F Crowley MJ | | 0，，： | 1 |
| 3 | Modulation of folliculogenesis and steroidogenesis in women by graded menotrophin administration显示文摘 | Filicori M Cognigni GE Pocognoli P | 2002 | Hum Reprod2002，17，8： | 1 |
| 4 | Modulation of folliculogenesis and steroidogenesis in women by graded menotrophin administration显示文摘 | Filicori M Cognigni GE Pocognoli P | 2002 | Hum Reprod JT-Human Reproduction(Oxford England)2002，17，8： | 1 |
| 5 | Error estimation in sampling digital wattmeters显示文摘 | FILICORI EMIRRID RINALDI M | 1985 | IEE ProcPartA1985，12，3： | 1 |
| 6 | Low-dose human chori- onic gonadotropin therapy can improve sensitivity to exogenous folli- cle-stimulating hormone in patients with secondary amenorrhea 显示文摘 | Filicori M Cognigni GE Taraborrelli S | 1999 | Fertil Steril1999，72，6： | 1 |
| 7 | Luteinizing hormone activity supplementation enhances follicle-stimulating hormone efficacy and improves ovulation induction outcome显示文摘 | Filicori M Cognigni GE Taraborrelli S | 1999 | J Clin Endocrinol Metab1999，84，8： | 1 |
| 8 | Three-dimensional CT volumetry predicts outcome of laparoscopic splenectomy for splenomegaly:retrospective clinical study显示文摘 | Filicori F Stock C Schweitzer AD | 2013 | World J Surg2013，37，1： | 1 |
| 9 | Hypogonadotropic disorders in men and women: diagnosis and therapy with pulsatilc gonadotropin-releasing hormone显示文摘 | Santoro N Filicori M Crowley WF Jr | 1986 | Endocr Rev1986，7，： | 1 |
| 10 | The role of luteinizing hormone in folliculogenesis and ovulation induction显示文摘 | Filicori M | 1999 | Fertil Steril1999，7，3： | 1 |
| 11 | Random asynchronous sampling strategy for measurement indtruments based on nonlinear signal coversion显示文摘 | Filicori F Luculano G Menchetti A | 1989 | Proc IEEE1989，136，3： | 1 |
| 12 | Modeling and control strategies for a variable reluctance direct-drive motor显示文摘 | FILICORI F LO BIANCO G C TONIELLI A | 1993 | IEEE Trans Ind Electron1993，40，2： | 1 |
| 13 | Subcutaneous administration of a depot gonodotropin-releasing hormone agonist induced profound reproductine axis suppression in women显示文摘 | FILICORI M COGNIGNI G E AMONE R | 1998 | Fertil Steril1998，69，： | 1 |
| 14 | Clinical review 126:Roles and novel regimens of luteinizing hormone and follicle-stimulating hor- mone in ovulation induction显示文摘 | Filicori M Cognigni G E | 2001 | J Clin Endocrinol Metab2001，86，4： | 1 |
| 15 | The role of luteinizing hormone in folliculogenesis and ovulation induction显示文摘 | | 1999 | Fertil Steril1999，71，3： | 1 |
| 16 | Comparison of controlled ovarian stimulation with human menopausal gonado- tropin or recombinant follicle-stimulating hormone显示文摘 | Filicori M Cognigni G E Pocognoli P | 2003 | Fertil Steril2003，80，2： | 1 |
| 17 | Characterization of the physiological pattern of episodic gonadotropin secretion throughout the human menstrual cycle显示文摘 | Filicori M Santoro N Merriam G R | 1986 | Clin Endocrinol Metab1986，62，6： | 1 |
| 18 | The use of LH activity to drive folliculogenesis :exploring uncharted territories in ovulation induction 显示文摘 | Filicori M Cognigni GE Samara A | 2002 | Hum Reprod Update2002，8，6： | 1 |
| 19 | The abnormal response of polycystic ovarian disease patients to exogenous pulsatile gonadotropin-releasing hormone:characterization and management显示文摘 | Filicori M Flamigni C Campaniello E | 1989 | J Clin Endocrinol Metab1989，69，4： | 1 |
| 20 | Error∞timation in sampEng dig-ita Iwattmeters显示文摘 | Filicori P F HilI L H | | 0，，： | 1 |
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