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836篇 您的检索式:作者名="Ferraris L"
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1全球药物滥用的疾病负担:来自2010年全球疾病负担研究显示文摘背景:直到目前还没有研究者系统地估计过全球及区域性的苯丙胺类、大麻、可卡因和阿片类药物依赖的患病率及其造成的疾病负担。我们旨在用伤残损失寿命年(YLDs)、过早死亡损失寿命年(YLLs)和伤残调整寿命年(DALYs)来估计药物依赖的患病率和其造成的疾病负担。方法:采用贝叶斯Meta回归的方法(Dis Mod-MR)对药物依赖的流行病学研究及2010年全球疾病、伤害及危险因素负担研究(GBD 2010)进行了系统综述,估计人群水平的药物依赖患病率。GBD 2010通过代表性社区调查和基于互联网的调查计算出新的失能权重。我们把估计的药物依赖患病率和新的失能权重结合起来估算药物依赖导致的YLDs、YLLs、DALYs和其作为相关疾病危险因素时导致的YLDs、YLLs和DALYs。结果:2010年,药物依赖直接造成了2千万的DALYs(95%UI(不确定区间)1.3-2.54千万),占全球全因DALYs的0.8%(0.6%-1.0%)。世界范围内,相比于其他药物,越来越多的人依赖于阿片类和苯丙胺类药物。阿片类药物依赖直接造成的疾病负担最大(DALYs为920万,95%UI为710-1140万)。在某些地区,药物依赖导致的DALYs所占比例比其他地区高出20倍,收入越高的国家药物依赖造成的负担所占比例也越高。注射吸毒所致HIV感染造成210万的DALYs(95%UI 110-360万),所致HCV感染导致50.2万的DALYs(95%UI 28.6-89.1万)。苯丙胺类药物依赖所致自杀造成85.4万的DALYs(95%UI 29.1-179.1万),阿片类药物依赖所致自杀造成67.1万的DALYs(95%UI 32.9-173.0万),可卡因依赖所致自杀造成32.4万的DALYs(95%UI 10.9-68.2万)。药物依赖导致的疾病负担最高的国家(>650 DALYs/10万人)包括美国,英国,俄罗斯和澳大利亚。结论:药物滥用是造成全球疾病负担的一个重要因素。为减少人群水平的疾病负担,我们需采取有效的措施(比如给予阿片类药物依赖者替代治疗及针具交换等)降低阿片类药物依赖和注射吸毒导致的疾病负担。王同瑜 Degenhardt L Whiteford HA Ferrari AJ Baxter AJ Charlson FJ Hall WD Freedman G Burstein R Johns Engell RE Flaxman A Murray CJ Vos T 2015中国药物依赖性杂志2015,24,6:3
2Early clinical worsening in patients with TIA or minor stroke: The Austrian Stroke Unit Registry显示文摘J Ferrari M Knoflach S Kiechl J Willeit S Schnabl L Seyfang W Lang 2010Neurology2010,,2:2
3Combined treatment with a β-blocker and intermittent PTH improves bone mass and mieroarehitecture in ovariectomized mice 显示文摘Pierroz D D Bouxsein M L Rizzoli R Ferrari S L 2006Bone2006,39,:1
4Protein kinase G from pathogenic mycobacteria promotes survival within macrophages显示文摘Walburger A Koul A Ferrari G Nguyen L PrescianottoBaschong C Huygen K Klebl B Thompson C Bacher G Pieters J 2004Science2004,304,5678:1
5Excimer laser intrastromal keratomileusis显示文摘Buratto L Ferrari M Rama P 1992Am J Ophthalmol1992,113,3:1
6Numerical simulation of flow interference be-tween two circular cylinders in tandem and side-by-side arrangements显示文摘Meneghini J R Saltara F Siqueira C L R Ferrari J A 2001Journal of Fluids and Struc-tures2001,15,2:1
7Do procalcitonin algorithms modify mortality显示文摘Ferrari L Casella F Podda GM 0,,02:1
8Development and in vitro evaluation of coated pellets conmining chitosan to potential colonic drug delivery显示文摘Ferrari PC Souza FM Giorgetti L 2013Carbohydr Polym2013,91,1:1
9A web-based distributed virtual educational laboratory显示文摘Benetazzo L Bertocco M Ferraris F 2000IEEE Transaction on Instrumentation and Measurement2000,49,2:1
10Characterization and clinical impact of antinuclear antibodies in primary biliary cirrhosis显示文摘Muratori P Muratori L Ferrari R 2003Am J Gasteroenterol2003,,2:1
11Laparoscopic myomectomy : technique, complications, and ultrasound scan evaluations 显示文摘Landi S Zaccoletti R Ferrari L 2001Jam Assoc Gynecol Laparosc2001,8,2:1
12Comparisons between PZT and PVDF thick films technologies in the design of low-cost pyroelectric sensors 显示文摘Capineri L Masotti L Ferrari V 2004Rev Sci lnstrum2004,75,11:1
13Two promoter polymorphisms regulating interleukin-6 gene expression are associated with circulating levels of C reactive protein and markers of bone resorption in postmenopausal women 显示文摘Ferrari SL Ahn-Luong L Garnero P 2003J Clin Endoerinol Metab2003,88,:1
14Drug therapy in metastatic neuroendocrine tufters of the gastroentero-pancreatic system显示文摘Pfaiss E Carnaghi C Ferrari L 1996Recent Results Canere Res1996,142,:1
15Clinical parameters, post- mortem analysis and estimation of lethal dose in victims of a massive intoxication with diethylene glycol显示文摘Ferrari LA Giannuzzi L 2005Forensic Sci Int2005,153,1:1
16Mirror neurons responding to obsevation of actions made with tools in monkey ventral premotor cortex显示文摘Ferrari PF Rozzi S Fogassi L 2005J Cogn Neurosc2005,17,2:1
17Chitosan -pectin multiparticulate systems associated with enteric polymers for colonic drug delivery显示文摘Oliveira G F Ferrari P C Carvalho L Q 2010Carbo Polym2010,82,:1
18Role of protein kinase G in growth and glutamine metabolism of Mycobacterium bovis BCG显示文摘Nguyen L Walburger A Houben E Koul A Muller S Morbitzer M Klebl B Ferrari G Pieters J 2005J Bacteriol2005,187,16:1
19Myopic peratonuleusis with the excimer laser: one-year follow-up 显示文摘Buratto L Ferrari M Gomisi C 1993Refract Corn Surg1993,9,:1
20Characterization and clinical impact of antinuclear antibodies in primary biliary cirrhosis显示文摘Muratori P Muratori L Ferrari R 2003Am J Gasteroenterol2003,,2:1
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