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| 1 | 固定低剂量三联抗高血压药物与常规治疗对斯里兰卡轻度至中度高血压患者血压控制的疗效差异:一项随机临床试验显示文摘控制不良的高血压是全球领先的公共卫生问题,需要新的治疗策略。该研究评估低剂量三联抗高血压药物治疗是否能达到比常规治疗更好的血压控制。研究者纳入2016年2月至2017年5月在斯里兰卡11所城市医院诊所就诊的需要开始抗高血压治疗(未治疗的患者)或接受单药治疗的患者,进行低剂量三联降压与常规治疗比较的随机、开放性试验,随访至2017年10月。 | Web-ster R Salam A de Silva HA Selak V Stepien S Rajapakse S Amarasekara S Amarasena N Billot L de Silva AP Fernando M Guggilla R Jan S Jayawardena J Maulik PK Mendis S Munasinghe J Naik N Prabhakaran D Ranasinghe G Thom S Tisserra N Senaratne V Wijekoon S Wijeyasingam S Rodgers A Patel A 刘莉 叶鹏 | 2018 | 中华高血压杂志2018,26,12: | 7 |
| 2 | Transcriptome analyses of the Dof-like gene family in grapevine reveal its involvement in berry, flower and seed development显示文摘The Dof(DNA-binding with one finger)protein family spans a group of plant transcription factors involved in the regulation of several functions,such as plant responses to stress,hormones and light,phytochrome signaling and seed germination.Here we describe the Dof-like gene family in grapevine(Vitis vinifera L.),which consists of 25 genes coding for Dof.An extensive in silico characterization of the VviDofL gene family was performed.Additionally,the expression of the entire gene family was assessed in 54 grapevine tissues and organs using an integrated approach with microarray(cv Corvina)and real-time PCR(cv Pinot Noir)analyses.The phylogenetic analysis comparing grapevine sequences with those of Arabidopsis,tomato,poplar and already described Dof genes in other species allowed us to identify several duplicated genes.The diversification of grapevine DofL genes during evolution likely resulted in a broader range of biological roles.Furthermore,distinct expression patterns were identified between samples analyzed,corroborating such hypothesis.Our expression results indicate that several VviDofL genes perform their functional roles mainly during flower,berry and seed development,highlighting their importance for grapevine growth and production.The identification of similar expression profiles between both approaches strongly suggests that these genes have important regulatory roles that are evolutionally conserved between grapevine cvs Corvina and Pinot Noir. | Danielle Costenaro da Silva Vítor da Silveira Falavigna Marianna Fasoli Vanessa Buffon Diogo Denardi Porto Georgios Joannis Pappas Jr Mario Pezzotti Giancarlo Pasquali Luís Fernando Revers | 2016 | Horticulture Research2016,3,1: | 5 |
| 3 | Coronary physiology assessment in the catheterization laboratory显示文摘Physicians cannot rely solely on the angiographic appearance of epicardial coronary artery stenosis when evaluating patients with myocardial ischemia. Instead, sound knowledge of coronary vascular physiology and of the methods currently available for its characterization can improve the diagnostic and prognostic accuracy of invasive assessment of the coronary circulation, and help improve clinical decision-making. In this article we summarize the current methods available for a thorough assessment of coronary physiology. | Felipe Díez-delhoyo Enrique Gutiérrez-Ibanes Gerard Loughlin Ricardo Sanz-Ruiz María Eugenia Vázquez-álvarez Fernando Sarnago-Cebada Rocío Angulo-Llanos Ana Casado-Plasencia Jaime Elízaga Francisco Fernández Avilés Diáz | 2015 | World Journal of Cardiology2015,7,9: | 2 |
| 4 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021,18,9: | 2 |
| 5 | Temporal features of different lightning events revealed from wavelet transform 显示文摘 | Sharma S R Cooray V Fernando M | 2011 | Journal of Atmospheric and Solar-Terrestrial Physics2011,73,4: | 1 |
| 6 | Characterisation of the deactivation of platinum and palladium supported on activated carbon used as hydrodechlorination catalysts显示文摘 | Salvador Ordo &ez Fernando D'iez V Herminio Sastre | 2001 | Applied Catalysis B: Environmental2001,31,: | 1 |
| 7 | Learning and optimization using the clonal selection principle显示文摘 | LEANDRO N D C FERNANDO J V Z | 2002 | IEEE Trans on Evolutionary Computation2002,6,3: | 1 |
| 8 | A prospective trial comparing the Holland nail with the dynamic hip screw in the treatment of intertrochanteric fractures of the hip显示文摘 | Little NJ Verma V Fernando C | 2008 | J Bone Joint Surg Br2008,90,8: | 1 |
| 9 | Intra mode selection for depth map coding to minimize rendcring distortions in 3D video 显示文摘 | DE SILVA D V S X FERNANDO W A C | 2009 | IEEE Transactions on Consumer Electronics2009,55,4: | 1 |
| 10 | Malignant nerve sheath tumour arising in a ganglioneuroma显示文摘 | Fletcher C D Fernando I N Braimbridge M V | 1988 | Histopatholo- gy1988,12,4: | 1 |
| 11 | Cuff-leak test for the diagnosis of upper airway obstruction in adults : a systematic review and meta-analysis 显示文摘 | Mafia E O Maria C M Fernando F V | 2009 | Intensive Care Med2009,35,7: | 1 |
| 12 | Combined effect of bacteriocins on the survival of various Listeria species in broth and meat system显示文摘 | GRACIELA V JORGE P FERNANDO S | 2000 | Curt Microbiol2000,41,6: | 1 |
| 13 | The effect of demand elasticity on security prices for the poolco and multilateral contract models 显示文摘 | Rajesh Rajaraiman Jayant V Sarlashkar Fernando L Alvarado | | IEEE Transactions on Power Systems0,,: | 1 |
| 14 | Invasive species can handle higher leaf temperature under water stress than Mediterranean natives显示文摘 | Oscar G Jose P L Fernando V | 2011 | Envi- ronmental and Experimental Botany2011,71,2: | 1 |
| 15 | Display dependent preprocessing of depth maps based on just noticeable depth difference modeling 显示文摘 | De Silva D V S X Ekmekcioglu E Fernando W A C | 2011 | IEEE Journal of Selected Topics in Signal Processing2011,5,2: | 1 |
| 16 | Evaluation of HIS,PCA and Wavelet Transform fusion techniques for the indentification of landslide scars using satellite data显示文摘 | Emerson V M Leila M G F Fernando V | 2003 | Anais XI SBSR Belo Horizonte Brasil 05-01 aBril INPE2003,,: | 1 |
| 17 | Bacillus thuringiensis survey in Brazil: geographical distribution and insecticidal activity against spodoptera frugiperda 显示文摘 | Fernando H V Marliton R B | 2003 | Neotropical Entomology2003,32,4: | 1 |
| 18 | Prohibitin deficiency blocks proliferation and induces apoptosis in human hepatoma cells: Molecular mechanisms and functional implications显示文摘 | VirginiaSánchez‐Quiles EnriqueSantamaría VíctorSegura LauraSesma JesúsPrieto Fernando J.Corrales | 2010 | Proteomics2010,,8: | 1 |
| 19 | Differences in the abundance and dis- tribution of copepods in two estuaries of the Basque coast ( Bay of Biscay) in relation to pollution 显示文摘 | IBON U FERNANDO V | 2005 | Journal of plankton Re- search2005,27,9: | 1 |
| 20 | Changes in solution color during phenol oxidation by Fenton reagent 显示文摘 | FEDERICO M FERNANDO V NATALIA V | 2006 | Environ Sci Technol2006,40,17: | 1 |