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| 1 | Potential use of serum HBV RNA in antiviral therapy for chronic hepatitis B in the era of nucleos(t)ide analogs显示文摘 | Fengmin Lu Jie Wang Xiangmei Chen Dongping Xu Ningshao Xia | 2017 | Frontiers of Medicine2017，11，4： | 28 |
| 2 | AFM research on Fe-based nanocrystal crystallization mechanism显示文摘The cross-section pattern of Fe-based alloy ribbon (Fe73.5Cu1Nb3Si13.5B9) annealed at different temperatures was investigated by AFM (atomic force microscope), and the effect mechanism of Nb and Cu in Fe-based alloy ribbon annealing was analyzed with XRD diffraction crystal analysis technique and other research results. New concepts of encapsulated grain, Nb vacancy cluster, Nb-B atom cluster and so on were proposed and used to describe the formation mechanism of α-Fe (Si) nanocrystal. Finally, a three-phase (separation phase, encapsulated phase and nanocrystalline phase) interconnected structure model in Fe-based nanocrystalline alloy was established. | FANG YunZhang WU FengMin ZHENG JinJu SHI FangYe WU WenHui SUN HuaiJun LIN GenJin MAN QiKui HU JuanMei YANG XiaoHong | 2008 | Science China(Technological Sciences)2008，51，1： | 8 |
| 3 | Tobacco RING E3 Ligase NtRFP1 Mediates Ubiquitination and Proteasomal Degradation of a Geminivirus-Encoded βC1显示文摘西红柿黄叶卷屈中国联系病毒的 betasatellite 编码的 C1 蛋白质作为一个致病力决定因素工作。更好理解 C1 在致病力工作的分子的基础,酵母一个烟草 cDNA 图书馆的二混血儿的屏幕作为诱饵用 C1 被执行。屏幕表明 C1 与烟草戒指手指蛋白质交往指明了 NtRFP1,它被双分子的荧光互补和 co-immunoprecipitation 试金进一步在 Nicotiana benthamiana 房间证实。NtRFP1 的表示被 C1 导致,并且在 vitro ubiquitination,试金证明 NtRFP1 是调停的功能的 E3 ubiquitin ligase C1 ubiquitination。另外, C1 被显示是在 vivo 的 ubiquitinated 并且由植物 26S proteasome 降级。在病毒的感染以后,植物 overexpressing NtRFP1 开发了稀释症状,而有 NtRFP1 的 silenced 表示的植物显示出严重症状。证据的另外的线证明 NtRFP1 通过由 26S proteasome 支持它的降级稀释导致 C1 的症状。一起拿,我们的结果建议烟草戒指 E3 ligase NtRFP1 由与 C1 交往调停稀释疾病症状它经由 ubiquitin/26S proteasome 系统的 ubiquitination 和降级。 | Qingtang Shen Tao Hu Min Bao Linge Cao Huawei Zhang Fengmin Song Qi Xie Xueping Zhou | 2016 | Molecular Plant2016，9，6： | 8 |
| 4 | Netrin-1 works with UNC5B to regulate angiogenesis in diabetic kidney disease显示文摘Netrin-1,an axon guidance factor,and its receptor UNC5B play important roles in axonal development and angiogenesis.This study examined netrin-1 and UNC5B expression in kidneys with diabetic kidney disease (DKD) and investigated their roles in angiogenesis.Netrin-1 and UNC5B were upregulated in streptozotocininduced DKD Wistar rats,and their expression was compared with that in healthy controls.However,exogenous netrin-1 in UNC5B-depleted human renal glomerular endothelial cells (HRGECs) inhibited cell migration and tubulogenesis.This effect was likely associated with SRC pathway deactivation.Netrin-1 treatment also eliminated the pro-angiogenic effects of exogenous VEGF-165 on UNC5B-silenced HRGECs.These results indicate that UNC5B antagonizes netrin-1 and that UNC5B upregulation contributes partly to enhancing angiogenesis in DKD.Therefore,introducing exogenous netrin-1 and depleting endogenous UNC5B are potential strategies for reducing the incidence of early angiogenesis and mitigating kidney injury in DKD. | Xiaojing Jiao Dong Zhang Quan Hong Lei Yan Qiuxia Han Fengmin Shao Guangyan Cai Xiangmei Chen Hanyu Zhu | 2020 | Frontiers of Medicine2020，14，3： | 7 |
| 5 | Uranium Provinces in China显示文摘Three uranium provinces are recognized in China, the Southeast China uranium province, the Northeast China-Inner Mongolia uranium province and the Northwest China (Xinjiang) uranium province. The latter two promise good potential for uranium resources and are major exploration target areas in recent years. There are two major types of uranium deposits: the Phanerozoic hydrothermal type (vein type) and the Meso-Cenozoic sandstone type in different proportions in the three uranium provinces. The most important reason or prerequisite for the formation of these uranium provinces is that Precambrian uranium-enriched old basement or its broken parts (median massifs) exists or once existed in these regions, and underwent strong tectonomagmatic activation during Phanerozoic time. Uranium was mobilized from the old basement and migrated upwards to the upper structural level together with the acidic magma originating from anatexis and the primary fluids, which were then mixed with meteoric water and resulted in | CHEN Zhaobo ZHAO Fengmin XIANG Weidong CHEN Yuehui | 2000 | Acta Geologica Sinica(English Edition)2000，74，3： | 7 |
| 6 | Knockdown of S-phase Kinase-associated Protein-2 Expression in MCF-7 Inhibits Cell Growth and Enhances the Cytotoxic Effects of Epirubicin显示文摘S 阶段联系 kinase 的 protein-2 (Skp2 ) 在调停 ubiquitin 的解朊作用起一个关键作用,导致房间从的前进一对一个 proliferative 状态静止。Skp2 完了在许多肿瘤表示了并且相反地与 p27 表示相关,包括乳癌。在这研究,我们使用了小介入的 RNA (siRNAs ) 在人的乳癌 MCF-7 细胞禁止 Skp2 表示并且如果击倒,从而由 RNA 干扰(RNAi ) Skp2 调查将禁止乳癌细胞生长并且在 MCF-7 细胞上影响 epirubicin 的效果。三 Skp2 siRNA 构造被重新结合并且短暂地 transfected 人乳癌 MCF-7 房间。Skp2 的下面规定被反向的抄写聚合酶链反应和蛋白质印迹分析证实。我们证明 Skp2 siRNA 转染减少了 Skp2 蛋白质并且在 MCF-7 房间导致了 p27 蛋白质的累积。Skp2 siRNA 在 vitro 并且在 vivo 禁止了房间增长。由 RNAi 的 Skp2 击倒在 vitro 的增加的细胞的 apoptosis。有治疗进一步与 epirubicin 跟随的 Skp2 siRNA 的治疗禁止了癌症房间线的增长,与 epirubicin 跟随的控制 siRNA 相比。因此, Skp2 击倒由 RNAi 的表示禁止乳癌细胞生长并且提高 epirubicin 的效果。Skp2 的调停 siRNA 的基因 silencing 能是为在规定下面的 p27 的抑制的新奇癌症基因治疗。 | Lichun SUN Li CAI Yan YU Qingwei MENG Xuesong CHENG Yanbin ZHAO Guangjie SUI Fengmin ZHANG | 2007 | Acta Biochimica et Biophysica Sinica2007，39，12： | 6 |
| 7 | An unbalanced PD-L1/CD86 ratio in CD14^++CD16^+ monocytes is correlated with HCV viremia during chronic HCV infection显示文摘 | Jiajia Zheng Hua Liang Chunhui Xu Qiang Xu Ting Zhang Tao Shen Fengmin LU | 2014 | Cellular & Molecular Immunology2014，11，3： | 6 |
| 8 | The modern change and evolution tendency of sand coast in the eastern area of Liaodong Gulf显示文摘The modern change and evolution tendency of sand coast in the eastern area of Liaodong GulfMiaoFengmin;BiZhaoqi;LiShuyuan;Xia... | Miao Fengmin Bi Zhaoqi Li Shuyuan Xiao Yuzhong Cong Peifu Zhuang Zhenye and Xu Weidong | 1995 | Acta Oceanologica Sinica1995，14，4： | 5 |
| 9 | Allelopathic inhibition on red tide microalgae Skeletonema costatum by five macroalgal extracts显示文摘This study aims to identify effective antialgal allelochemicals from marine macroalgae that inhibit the growth of red tide microalgae.Practically,new algicidal agents were developed to control red tide.The growth inhibitory effects of 5 marine macroalgae Porphyra tenera,Laminaria japonica,Ulva pertusa,Enteromorpha clathrata,and Undaria pinnatifida on Skeletonema costatum were evaluated by adding crude seawater extracts of macroalgal dry tissue into the culture medium containing S.costatum.The half-effective concentrations at 120 h(EC_(50),120 h)of the seawater extracts were 0.6,0.9,1.0,1.0,and 4.7 g/L for the five macroalgae above,respectively.E.clathrata,L.japonica and U.pertusa showed strong allelopathic effect on the growth of S.costatum.There have been no previous reports with regard to the allelopathic effects of the former two macroalgae so far.The possible allelochemicals of 21 compounds of the E.clathrata were detected using Gas chromatography-mass spectrometry(GC-MS)analysis.Unsaturated fatty acids,acrylic acid(C_(3)H_(4)O_(2)),and linolenic acid(C_(18)H_(30)O_(2))were the most likely allelochemicals in E.clathrata. | Zhen AN Zhenyu WANG Fengmin LI Zhijia TIAN Hongying HU | 2008 | Frontiers of Environmental Science & Engineering2008，2，3： | 4 |
| 10 | Preliminary results of a new global ocean reanalysis显示文摘Using a new global ocean reanalysis of the second generation Global Ocean Data Assimilation System of the Beijing Climate Center(BCC_GODAS2.0) spanning the period 1990-2009,we firstly quantify the accuracy of BCC_GODAS2.0 in representing the temperature and salinity by comparing with OISST and SODA data.The results show that the assimilation system may effectively improve the estimations of temperature and salinity by assimilating all kinds of observations,especially in the equatorial eastern Pacific.Moreover,the root mean square errors of monthly temperature and salinity are respectively reduced by 0.53℃ and 0.28 psu,compared with the model control simulation results.Then,the applicability of this ocean reanalysis for sea surface temperature(SST) anomaly variability in the tropical Pacific is evaluated with the observational HadISST data.The NINO3 index of the new reanalysis shows a good agreement with that of HadISST,with a correlation of 93.6%.Variations in SST from BCC_GODAS2.0 are similar to those obtained from HadISST data along the equator,showing the major large zonal-scale features such as the strong magnitude of seasonal cycle.The amplitude of SST anomaly standard deviation in the equatorial eastern Pacific is also closer to observations(HadISST) than NCEP GODAS does.Besides,the first two leading empirical orthogonal function(EOF) modes of the monthly SST anomalies over the tropical Pacific region are explored.The EOF1 pattern of BCC_GODAS2.0 captures a traditional El Ni o pattern,which improves magnitudes of the positive SST anomaly in the cold tongue of the eastern Pacific.The EOF2 pattern exhibits a El Ni o Modoki pattern.Comparatively,the EOF2 pattern of BCC_GODAS2.0 extends more strongly toward the subtropics.It also overcomes the problem that negative loadings are confined in the narrow equatorial eastern Pacific.Consequently,the magnitude and spatial distribution of the leading EOF patterns of BCC_GODAS2.0 are well consistent with those of HadISST. | WANG DongXiao QIN YingHao XIAO XianJun ZHANG ZuQiang WU FengMin | 2012 | Chinese Science Bulletin2012，57，26： | 4 |
| 11 | Thermodynamic functions of ZrW_2O_8 from its heat capacity显示文摘It is interesting to maximize the amount of information we can obtain from one experiment on a single sample.In obtaining all the thermodynamic properties of some materials from their experimental heat capacity data only,we aim to get the temperature-independent energy spectrum.However,all the practical measured energy spectra depend on the temperature of experiments.One promising method to obtain the temperature-independent energy spectrum is to solve the so-called specific heat-phonon spectrum inversion(SPI) problem.Here we show,by developing a new practical solution method of SPI,the phonon spectrum of the negative thermal expansion material ZrW 2 O 8 is obtained.This phonon spectrum is temperature-independent and almost method independent.Hence all the thermodynamic properties of ZrW 2 O 8,such as thermodynamic potential,entropy,Helmholtz free energy,etc.are obtained by heat capacity only. | Ji FengMin DAI XianXi STEVENS R GOATES J B | 2012 | Science China(Physics,Mechanics & Astronomy)2012，55，4： | 3 |
| 12 | A new solution method for black-body radiation inversion and the solar area-temperature distribution显示文摘The effective temperature of the solar photosphere is usually obtained according to the solar constant, based on the Stefan-Boltzmann law. However its temperature distribution is not homogeneous. A hopeful way to obtain the area-temperature distribution of the solar photosphere is to solve the Black-body Radiation Inversion (BRI) problem. In this paper, a new practical solution method for BRI is developed. The theoretical analysis and numerical calculations show the low-temperature distribution difficulty of BRI is solved by this new method. Then the area-temperature distribution of the solar photosphere is obtained, according to the measured absolute solar spectral irradiance. It is the first realization of BRI for a real system after almost three decades of efforts. The results are comparable to that from the Stefan-Boltzmann law. | JI FengMin DAI XianXi | 2011 | Science China(Physics,Mechanics & Astronomy)2011，54，11： | 3 |
| 13 | Efficient projected gradient methods for cardinality constrained optimization显示文摘Sparse optimization has attracted increasing attention in numerous areas such as compressed sensing, financial optimization and image processing. In this paper, we first consider a special class of cardinality constrained optimization problems, which involves box constraints and a singly linear constraint. An efficient approach is provided for calculating the projection over the feasibility set after a careful analysis on the projection subproblem. Then we present several types of projected gradient methods for a general class of cardinality constrained optimization problems. Global convergence of the methods is established under suitable assumptions. Finally, we illustrate some applications of the proposed methods for signal recovery and index tracking.Especially for index tracking, we propose a new model subject to an adaptive upper bound on the sparse portfolio weights. The computational results demonstrate that the proposed projected gradient methods are efficient in terms of solution quality. | Fengmin Xu Yuhong Dai Zhihu Zhao Zongben Xu | 2019 | Science China Mathematics2019，62，2： | 2 |
| 14 | Determination of Heavy Metals in Tobacco by ICP-MS and Analysis of Uncertainty显示文摘The research aims to set up the determination method of heavy metals in tobacco by ICP-MS and analyze its uncertainty. Microwave digest technique is used for decomposition of the tobacco samples. Bi,Sc,Ge and In are employed as internal standards to eliminate the interference of the matrix. A method is developed for simultaneous determination of Cr,Cu,As,Cd,Hg and Pb in tobacco from Yunnan Province by ICP-MS,and the measurement uncertainty is evaluated by metrological method. The test results indicate that in the content range of0- 1. 0 g / ml,the linearly dependent coefficient of six elements is 1. 0000,and the RSD achieves 1. 5%- 11%( n = 8). The elemental content in tobacco is as follows: Cr( 2. 92,0. 24) mg / kg,Cu( 3. 64,0. 24) mg / kg,As( 0. 467,0. 025) mg / kg,Cd( 3. 12,0. 15) mg / kg,Hg( 0. 035,0. 006) mg/kg,Pb( 4. 62,0. 36) mg/kg. The uncertainty of sample size,the constant volume of the sample solution can be neglected. It is concluded that the method is accurate,simple,sensitive and rapid. | Bo YANG Fengmin DUAN Jinling DING Zhijuan BAO | 2016 | Asian Agricultural Research2016，8，10： | 2 |
| 15 | Current Development Situation and Prospects of Blueberry in Guangdong Province显示文摘With high nutrition and health value,blueberry receives much concern in recent years. Blueberry experts in the world are cultivating new blueberry varieties. They have come up with constructive theoretical support and planting technology researches and are constantly devoted to expanding blueberry planting latitudes. This paper elaborated researches of blueberry at home and abroad,current development situation of blueberry in China and Guangdong Province,analyzed strengths of planting blueberry in Guangdong. Besides,it came up with recommendations for development of blueberry industry. Finally,it discussed development prospects of blueberry planting in Guangdong. | Lixia GAO Hualan XIAO Sen LI Fengmin LIU Aiqiong MO | 2015 | Asian Agricultural Research2015，7，9： | 2 |
| 16 | Drought Resistance of Twelve Desert Shrubs at Seedling Stage of Ulan Buh Desert Ecosystem显示文摘[Objective] To establish drought resistance evaluation index system of desert shrubs,and provide scientific support for selecting quality tree species.[Method] Taking 2-year-old seedlings of 12 desert shrubs in Ulan Buh Desert ecosystem as the test materials,7 water physiological indexes were tested,principal component analysis and cluster analysis were applied to explore drought resistance of the shrubs.[Results](a) Water potential of Ephedra distachya Linn.,Nitraia tangutorum Bobr.,Caragana korshinski Kom.was lower than that of the other 9 species;bound water content(V_a) and bound water/free water ratio(V_a/V_s) of Zygophyl um xanthoxylon Maxim.was 64.20% and 3.3,higher than the others';transpiration rate of Atraphaxis bracteata A.Los.,Nitraia tangutorum Bobr.and Tamarix elongata Ldb.was significantly lower than the others';constant weight time of Haloxylon ammodendron(C.A.Mey.) Bunge and Ephedra distachya Linn.was the longest(144 h);residual moisture content of Ammopiptanthus mongolicus Maxim.was the highest(44.80%).(b) Water potential,bound water/free water(V_a/V_s),residual moisture content,bound water,constant weight time,and transpiration rate had great impact on drought resistance of plant,and the accumulative variance contribution rate achieved 87.59%.[Conclusion] According to the drought resistance,the 12 species were classified into 3 categories,namely shrubs with strong drought resistance(Ephedra distachya Linn.),shrubs with moderate drought resistance(Haloxylon ammodendron(C.A.Mey.) Bunge,Nitraia tangutorum Bobr.,and Zygophyllum xanthoxylon Maxim.);shrubs with poor drought resistance(Hedysarunn scoparium Fisch,Hedysarum mongolicum Turcz.,Tamarix elongata Ldb.,Caragana korshinskii Kom.,Ammopiptanthus mongolicus Maxim.,Atraphaxis bracteata A.Los.,Cal igonum mongolicum Mattei.,and Caragana microphylla Lam.). | JIA Yukui LUO Fengmin ZHANG Jingbo GAO junliang XIN Zhiming LIU Fang | 2016 | Journal of Landscape Research2016，8，6： | 2 |
| 17 | Adaptive projected gradient thresholding methods for constrained l0problems显示文摘In this paper, we propose and analyze adaptive projected gradient thresholding(APGT) methods for finding sparse solutions of the underdetermined linear systems with equality and box constraints. The general convergence will be demonstrated, and in addition, the bound of the number of iterations is established in some special cases. Under suitable assumptions, it is proved that any accumulation point of the sequence generated by the APGT methods is a local minimizer of the underdetermined linear system. Moreover, the APGT methods, under certain conditions, can find all s-sparse solutions for accurate measurement cases and guarantee the stability and robustness for flawed measurement cases. Numerical examples are presented to show the accordance with theoretical results in compressed sensing and verify high out-of-sample performance in index tracking. | ZHAO ZhiHua XU FengMin LI XiangYang | 2015 | Science China Mathematics2015，58，10： | 2 |
| 18 | H_2S Gas Sensitivity of Nanocrystalline Tin Dioxide Doped with Ytterbium (Yb) and Praseodymium (Pr)显示文摘<正>The influence of Yb_2O_3 and Pr_2O_3 doping on electrical and gas sensing properties of tin dioxide was studied.A doping content of 0.5wt%~5wt% was investigated by mechanical mixing.The significant improvement on sensitivity and selectivity to 200μg/g hydrogen sulphide gas has been achieved by 3wt% Pr_2O_3 and 5wt% Yb_2O_3 adding.The better response and revovery properties of Pr or Yb doped tin dioxide sensor for 200μg/g hydrogen sulphide gas were found.The maximum sensitivity to H_2S gas is observed at about 120℃.Pr has stronger catalysis than Yb for H_2S reaction on SnO_2 surface.S~ 2-) was oxidized to S~ 6+) on the SnO_2 surface according to XPS. | Fengmin Liu Xishuang Liang Yuehua He Biao Wang Baofu Quan | 2006 | 稀有金属材料与工程2006，35，A03： | 2 |
| 19 | Inception of the Modern Public Health System in China and Perspectives for Effective Control of Emerging Infectious Diseases:In Commemoration of the 140th Anniversary of the Birth of the Plague Fighter Dr.Wu Lien-Teh显示文摘Infectious diseases pose a serious threat to human health and affect social,economic,and cultural development.Many infectious diseases,such as severe acute respiratory syndrome(SARS,2013),Middle East respiratory syndrome(MERS,2012 and 2013),Zika virus infection(2007,2013 and 2015),and coronavirus disease 2019(COVID-19,2019),have occurred as regional or global epidemics(Reperant and Osterhaus 2017;Gao 2018)。 | Qingmeng Zhang Niaz Ahmed George F.Gao Fengmin Zhang | 2020 | Virologica Sinica2020，35，6： | 2 |
| 20 | Pneumonic plague epidemic in Northeast China in 1910-1911: Dr. Wu Lien-Teh's epidemic preventive system for plague control显示文摘在俄语的西伯利亚发源的肺的瘟疫在 10 月 1910March 日 1911 爆发在东北中国。根据有本地当局和国际同事的地访问,尸体,细菌学的鉴定,和靠近的合作,吴博士 Lien-Teh 实现了一系列有效 antiplague 措施,它成功地控制了非凡的流行瘟疫的发展。在他的随后的工作,吴博士在这传播表明了肺的瘟疫和 tarbagans 角色的呼吸传播。伍斯博士大学教师和文化贡献在在中国的医药进步是珍贵的。 | Qingmeng Zhang Fengmin Zhang Baofeng Yang | 2018 | Frontiers of Medicine2018，12，1： | 2 |
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