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| 1 | 高光谱最优波长选择及Fisher判别分析法判别玉米颗粒表面黄曲霉毒素显示文摘黄曲霉毒素是广泛存在于玉米中且具有剧毒的一种代谢产物,以美国农业部农业研究署(USDA-ARS) Toxicology and Mycotoxin Research Unit提供的2010年先锋玉米为研究对象,验证了高光谱成像技术对玉米中黄曲霉毒素检测的可行性。以甲醇为溶剂制备四种不同浓度的黄曲霉毒素溶液,并将其逐一滴在等量的4组共120粒玉米颗粒表面,以未处理的30粒洁净玉米作为一组对照样本,将大小、形状相似的150个样品随机分为训练集103个,验证集47个;对获取的400~1000 nm波段范围内的高光谱图像,先进行标准正态变量变换(standard normal variate transformation ,SNV)预处理,然后引入基于 Fisher判别最小误判率的方法选择最优波长,并以所选波长作为Fisher判别分析法的输入建立判别模型,对玉米颗粒表面不同浓度的黄曲霉毒素进行识别,最后对模型判别正确率进行了验证。结果表明,选取四个最优波长(812.42,873.00,900.36和965.00 nm )时Fisher判别分析模型对训练集与验证集的准确率分别为87.4%和80.9%。该方法为含黄曲霉毒素玉米颗粒便携式检测仪器的开发,以及对田间霉变玉米自然代谢产生毒素的检测奠定了技术基础。 | 褚璇 王伟 张录达 郭浪花 Peggy Feldner Gerald Heitschmidt | 2014 | 光谱学与光谱分析2014，34，7： | 22 |
| 2 | Management of hepatitis C in patients with chronic kidney disease显示文摘Hepatitis C virus(HCV) infection is highly prevalent among chronic kidney disease(CKD) subjects under hemodialysis and in kidney transplantation(KT) recipients, being an important cause of morbidity and mortality in these patients. The vast majority of HCV chronic infections in the hemodialysis setting are currently attributable to nosocomial transmission. Acute and chronic hepatitis C exhibits distinct clinical and laboratorial features, which can impact on managementand treatment decisions. In hemodialysis subjects, acute infections are usually asymptomatic and anicteric; since spontaneous viral clearance is very uncommon in this context, acute infections should be treated as soon as possible. In KT recipients, the occurrence of acute hepatitis C can have a more severe course, with a rapid progression of liver fibrosis. In these patients, it is recommended to use pegylated interferon(PEG-IFN) in combination with ribavirin, with doses adjusted according to estimated glomerular filtration rate. There is no evidence suggesting that chronic hepatitis C exhibits a more aggressive course in CKD subjects under conservative management. In these subjects, indication of treatment with PEG-IFN plus ribavirin relies on the CKD stage, rate of progression of renal dysfunction and the possibility of a preemptive transplant. HCV infection has been associated with both liver disease-related deaths and cardiovascular mortality in hemodialysis patients. Among those individuals, low HCV viral loads and the phenomenon of intermittent HCV viremia are often observed, and sequential HCV RNA monitoring is needed. Despite the poor tolerability and suboptimal efficacy of antiviral therapy in CKD patients, many patients can achieve sustained virological response, which improve patient and graft outcomes. Hepatitis C eradication before KT theoretically improves survival and reduces the occurrence of chronic graft nephropathy, de novo glomerulonephritis and post-transplant diabetes mellitus. | Roberto J Carvalho-Filho Ana Cristina CA Feldner Antonio Eduardo B Silva Maria Lucia G Ferraz | 2015 | World Journal of Gastroenterology2015，21，2： | 4 |
| 3 | In vitro torque deformation charac teristics of orthodontic polycarbonate brackets显示文摘 | Feldner JC Sarkar NK | 1994 | Ame J Orthodont Dentofa Orthope1994，106，3： | 1 |
| 4 | Pregnancy after uterine arterial embolization 显示文摘 | Bonduki CE Feldner JP Silva J | 2011 | Clinics (Sao Paulo)2011，66，： | 1 |
| 5 | Correlation between valsalva leak point pressure and maximal urethral closure pressure in women with stress urinary incontinence 显示文摘 | Feldner P C Jr Bezerra L R de Castro R A | 2004 | Int Urogynecol J Pelvic Floor Dysfunct2004，15，3： | 1 |
| 6 | Bortezomib pro- tects from varicose-like venous remodeling显示文摘 | PFISTERER L MEYER R FELDNER A et at | 2014 | Faseb J2014，28，8： | 1 |
| 7 | Temporal relations between sleep problems and both traumatic event exposure and PTSD: a critical review of the empirical literature显示文摘 | Babson K A Feldner M T | 2010 | J Anxiety Dis- ord2010，1，24： | 1 |
| 8 | Pregnancy after uterine arterial embolization显示文摘 | Bonduki CE Feldner JPC Silva Jd | 2011 | Clinics2011，66，5： | 1 |
| 9 | Cancer cell motility-on the road from c-erbB-2 receptor steered signaling to actin reorganization 显示文摘 | Brandt BH | 2002 | Exp Cell Res2002，272，2： | 1 |
| 10 | A critical analysis of approaches to targeted PTSD prevention: current status and theoretically derived fu- ture directions 显示文摘 | Feldner MT onson CM Friedman MJ | 2007 | Behav Modif2007，31，1： | 1 |
| 11 | Junb regulates arteri- al contraction capacity, cellular contractility, and motility via its target Myl9 in mice显示文摘 | Licht AH Nubel T Feldner A | 2010 | J Clin Invest2010，120，7： | 1 |
| 12 | Endothelial cell ephrinB2-dependent activation of monocytes in arteriosclerosis显示文摘 | Braun J Hoffmann SC Feldner A | 2011 | Arterioscler Thromb Vasc Biol2011，31，2： | 1 |
| 13 | 查看详情显示文摘 | Feldner BD Rainhardt RA Garbin CP | | 0，，： | 1 |
| 14 | Pregnancy after uterine arterial embolization显示文摘 | Bonduki CE Feldner JP Silva J | 2011 | Clinics(Sao Paulo)2011，66，12： | 1 |
| 15 | Temporal relations between sleep problems and both traumatic event exposure and PTSD: a critical review of the empirical literature 显示文摘 | Babson KA Feldner MT | 2010 | J Anxiety Disorders2010，1，24： | 1 |
| 16 | Sexual steroids in urogynecology显示文摘 | Sartori MG Feldner PC Jarmy-Di Bella ZI | 2011 | Climacteric2011，14，1： | 1 |
| 17 | Synaptojanin-2 binding protein stabilizes the Notch ligands DLL1 and DLL4 and inhibits sprouting angiogenesis显示文摘 | Adam MG Berger C Feldner A | 2013 | Circ Res2013，113，11： | 1 |
| 18 | Posttraumatic stress symptoms and smoking to reducee negative affect:An in-vestigation of trauma-exposed daily smokers显示文摘 | Feldner MT Babson KA Zvolensky MJ | 2007 | Addict Be-hav2007，32，2： | 1 |
| 19 | Pregnancy affer uterine arterial embolization显示文摘 | Bonduld CE Feldner Jr PC Silva Jd | 2011 | Clinics (Sao Panlo)2011，66，5： | 1 |
| 20 | Anterior vaginal wall prolapse : a randomized controlled trial of SIS graft versus traditional colporrhaphy 显示文摘 | Feldner PC Jr Castro RA Cipolotti LA | 2010 | Int Urogynecol J2010，21，9： | 1 |
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