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| 1 | Surgical management of moderate ischemic mitral valve regurgitation: Where do we stand?显示文摘Ischemic mitral regurgitation(IMR) represents a common complication after myocardial infarction. The valve is anatomically normal and the incompetence is the result of papillary muscles displacement and annular dilatation, causing leaflets tethering. Functionally the leaflets present a restricted systolic motion due to tethering forces that displaces the coaptation surface toward the left ventricle apex. The patients present poor left ventricular function at the time of surgery and the severity of the mitral regurgitation increases the risk of mortality. Currently there is general agreement to treat surgically severe IMR nevertheless strong evidences for patient with moderate insufficiency remains poor and proper treatment debated. The most effectivesurgical approach for the treatment of IMR remains debated. Some authors demonstrated that coronary artery bypass graft(CABG) alone is beneficial in patients with IMR. Conversely, in most patients, moderate IMR will persist or worsen after CABG alone which translate in higher long-term mortality as a function of residual mitral regurgitation severity. A probable reason for this unclear surgical management of functional MR is due to the contemporary suboptimal results of reparative techniques. The standard surgical treatment of chronic IMR is CABG associated with undersized annuloplasty using complete ring. Though, the recurrence of mitral regurgitation remains high(> 30%) because of continous left ventricle remodeling. To get better long term results, in the last decade, several subvalvular procedures in adjunct to mitral anuloplasty have been developed. Among them, surgical papillary muscle relocation represents the most appreciated option capable to restore normal left ventricle geometry. In the next future new preoperative predictors of increased mitral regurgitation recurrence are certainly needed to find an individual time period of treatment in each patient with moderate IMR. | Khalil Fattouch Sebastiano Castrovinci Giacomo Murana Marco Moscarelli Giuseppe Speziale | 2014 | World Journal of Cardiology2014，6，11： | 5 |
| 2 | Aortic valve stenosis: treatments options in elderly high-risk patients显示文摘 | Khalil Fattouch Sebastiano Castrovinci Patrizia Carita | 2016 | Journal of Geriatric Cardiology2016，13，6： | 4 |
| 3 | Aortic stenosis: insights on pathogenesis and clinical implications显示文摘大动脉的狭窄(作为) 是在西方的人口的普通的瓣膜的心疾病,与在在 75 年的成年人的 3% 的估计的全面流行。为了理解它的 patho 生物的过程,代表优先级。在老病人,作为通常包含 trileaflet 阀门并且被叫作退化石灰质的过程。科学证据建议活跃 “ 的参与; atherosclerosis-like”在开始阶段的致病退化作为。到矛盾,前进能被不同力量驾驶(例如在发炎和石灰化之间的机械应力,基因因素和相互作用) 。改进理解为阻止并且禁止疾病的发展和前进介绍潜在地新的治疗学的目标。而且,在临床的实践管理作为病人暗示概括动脉粥样硬化患者表明的评估(即,在里面冠并且颈动脉动脉) 甚至为预示的原因。在 counselling 老病人,风险层化应该超过通用风险分数探讨单个脆弱。在这些,问候,合作病态,和特别地那些连接了到全球动脉粥样硬化患者负担,应该小心地被调查以便为侵略治疗策略定义风险 / 利益比率。我们在场在致病的卓见的详细概述就象可能的实际含意。 | Patrizia Carita Giuseppe Coppola Giuseppina Novo Giuseppa Caccamo Marco Guglielmo FabioBalasus Salvatore Novo Sebastiano Castrovinci Marco Moscarelli Khalil Fattouch Egle Corrado | 2016 | Journal of Geriatric Cardiology2016，13，6： | 3 |
| 4 | POINT: Efficacy of adding mitral valve restrictive annuloplasty to coronary artery bypass grafting in patients with moderate ischemic mitral valve regurgitation: A randomized trial显示文摘 | Khalil Fattouch Francesco Guccione Roberta Sampognaro Gaetano Panzarella Egle Corrado Emiliano Navarra Davide Calvaruso Giovanni Ruvolo | 2009 | The Journal of Thoracic and Cardiovascular Surgery2009，，2： | 2 |
| 5 | Cramer-Rao bounds for the estimation of multipath parameters and mobiles positions in asynchronous DS-CDMA systems 显示文摘 | BOTTERON C MADSEN A H FATTOUCHE M | 2004 | IEEE Trans on Signal Processing2004，52，4： | 1 |
| 6 | Applications of Minimum Redundancy Arrays in Adaptive Beamforming显示文摘 | Jorgenson M B Fattouche M Nichols S T | 1991 | IEE Proceedings on Microwaves Antennas and Propagation1991，138，5： | 1 |
| 7 | Beneficial effects of C1 esterase inhibitor in ST-elevation myocardial infarction in patients who underwent surgical reperfusion: a randomised double-blind study显示文摘 | Fattouch K Bianco G Speziale G | 2007 | European Journal of Cardio-thoracic Surgery2007，32，： | 1 |
| 8 | Diffusion-weighted magnetic resonance imaging in patients with partial status epilepticus显示文摘 | Di Bonaventura C Bonini F Fattouch J | 2009 | Epilepsia2009，50，1： | 1 |
| 9 | Long-term results after repair of type a acute aortic dissection according to false lumen patency显示文摘 | Fattouch K Sampognaro R Navarra E | | 0，，： | 1 |
| 10 | Frequency Response and Path Loss Measurements of Indoor Channels显示文摘 | ZAGHLOUL H MORRISON G FATTOUCHE M | | 0，，12： | 1 |
| 11 | Applications of Minimum Redundancy Arrays in Adaptive Beamformin0显示文摘 | Jorgenson M B Fattouche M Nichols S T | 1991 | lEE Proceedings-H Microwaves Antennas and Propagation1991，138，5： | 1 |
| 12 | Comparison of indoor Propagation Channel Characteristics at Different Frequencies显示文摘 | ZAGHLOUL H MORRISON G FATTOUCHE M | | 0，，22： | 1 |
| 13 | Inhaled prostacyclin, nitric oxide and nitroprusside in pulmonary hypertension after mitral valve replacement 显示文摘 | Fattouch K Sbraga F Bianco G | 2005 | J Card Surg2005，20，2： | 1 |
| 14 | Impact of moderate ischemic mitral regurgitation after isolated coronary artery bypass grafting显示文摘 | Fattouch K Sampognaro R Speziale G | 2010 | Ann Thorac Surg2010，90，4： | 1 |
| 15 | Robust positioning systems in the presence of outliers under weak GPS signal conditions显示文摘 | Fallahi K Chi-Tsun Cheng and Fattouche M | 2012 | IEEE Systems Journal2012，6，3： | 1 |
| 16 | Clinical experience with levetiracetam in idiopathic generalized epilepsy according to different syndrome subtypes显示文摘 | Di Bonaventura C Fattouch J Mari F | 2005 | Epilaptic Disord2005，7，： | 1 |
| 17 | Impact of moderate ischemic mitral regurgitation after isolated coronary artery bypass grafting显示文摘 | Fattouch K Sampognaro R Speziale G | 2010 | AnnThorac Surg2010，90，4： | 1 |
| 18 | Inhaled prostacyclin,nitric oxide,and nitroprusside in pulmonary hypertension after mitral valve replacement 显示文摘 | Fattouch K Sbraga F Bianco G | 2005 | J Card Surg2005，20，2： | 1 |
| 19 | Quince ( Cydonia oblonga Miller) peel polyphenols modulate LPS-induced inflammation in human THP-1-derived macrophages through NF-κB, p38MAPK and Akt inhibition显示文摘 | Khadija Essafi-Benkhadir Amira Refai Ichrak Riahi Sami Fattouch Habib Karoui Makram Essafi | 2012 | Biochemical and Biophysical Research Communications2012，，1： | 1 |
| 20 | Treatment of pulmonary hypertension in patients undergoing cardiac surgery with cardiopulmonary bypass:a randomized,prospective,double -blind study显示文摘 | Sbraga F Sampognaro R | 2006 | J Cardiovasc Med (Hagerstown)2006，7，2： | 1 |
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