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| 1 | The influence of nitroglycerin on the proliferation of endothelial progenitor cells from peripheral blood of patients with coronary artery disease显示文摘Endothelial 祖先房间(EPC ) 与脉管的修理和动脉粥样硬化患者损害的前进被联系。如果传播 EPC 失去他们的函数,它可以导致冠的动脉疾病(CAD ) 。连续硝化甘油(NTG ) 治疗原因增加了脉管的氧化应力和 endothelial 机能障碍。这研究的目的是在人的外部导出血的 EPC 的增长上调查 NTG 的效果。EPC 文化,从 60 个 CAD 病人镇定、为 712 天有教养,分别地为 72 h 与 NTG (0.0, 0.3, 1.0, 2.0, 7.5, 15.0,和 20.0 mg/l ) 的不同集中被对待。房间计数和 EPC 的 proliferative 活动;脉管的 endothelial 生长因素的层次 -- 一(VEGF -- 一) ,氮的氧化物(没有) 并且 peroxynitrite (在文化媒介的 ONOO ) ;并且在支持者房间的反应的氧种类(ROS ) 的水平被测量。与控制(0.0 mg/l NTG ) 相比,当与 1.0 mg/l NTG 对待并且当 NTG 集中是 7.5 mg/l 时,到达了最大的水平时, EPC 的房间数字和 proliferative 活动被增加。然而,当与 NTG (15.0 mg/l ) 的更高的剂量对待时,有重要减小。同时, VEGF -- 表情与 7.5 mg/l NTG 到达了它的最大的表示,但是逐渐地与 NTG 的更高的剂量由孵化衰退了。在没有水平和 NTG 集中之间有一种线性关系,但是当 EPC 与 0.37.5 mg/l NTG 被孵化时, ONOO 的变化和 ROS 层次都没被发现。然而,当与 15 和 20 mg/l NTG 孵化了时, ONOO 和 ROS 层次显著地被增加。我们的数据证明 NTG 的那中等剂量可以刺激从 CAD 病人孤立的 EPC 的 proliferative 活动。 | Xin Wang Caiyu Zeng Huiping Gong Hong He Mengxin Wang Qin Hu Falin Yang | 2014 | Acta Biochimica et Biophysica Sinica2014,46,10: | 4 |
| 2 | GWAS-identified colorectal cancer susceptibility locus associates with disease prognosis显示文摘 | Jinliang Xing Ronald E. Myers Xianli He Falin Qu Feng Zhou Xi Ma Terry Hyslop Guoqiang Bao Shaogui Wan Hushan Yang Zhinan Chen | 2011 | European Journal of Cancer2011,,11: | 1 |
| 3 | Sea surface height measuring using InSAR altimeter显示文摘Satellite altimetry has been widely used in measuring ocean topography from space.The conventional altimeter system is the nadir radar altimeter system which has the limitations of one-dimensional measurement and is unable to get both high temporal and spatial resolution.The InSAR altimetry system using InSAR altimeter instead of nadir radar altimeter is an improvement which can get both high cross-track and along-track resolution and wide swath.However,the conventional SAR interferometry only can achieve meter level height accuracy.This paper focuses on a method of radar echo-tracking for InSAR altimeter system in order to correct the slant range measurements and finally to improve the height measurement accuracy to several centimeters' level.Radar slant range(from observed pixels to radar antenna) estimation error affects the height measurement accuracy badly,nevertheless not considered in the conventional SAR interferometry.The proposed method is ameliorated based on the traditional echo-model used in nadir radar altimeter system,focusing on the echo signals from observed pixels with different incident angles.Simulations of sea surface height measurements are performed in the last part of this paper,and the conclusions are drawn that,with corrected slant range,the accuracy of InSAR altimetry can be much better than the conventional SAR interferometry. | Xiaohong Sui Running Zhang Falin Wu Yang Li Xiaoyun Wan | 2017 | Geodesy and Geodynamics2017,8,4: | 1 |
| 4 | Complete estrogen receptor blocker ICI182,780 promotes the proliferation of vascular smooth muscle cells显示文摘ICI182,780 在乳癌的辅助治疗被使用。作为完全的雌激素受体(嗯) blocker, ICI182,780 可以在心血管的系统上反对雌激素的效果。雌激素禁止脉管的光滑的肌肉房间(VSMC ) 的增长,它是雌激素能施加的机制之一 cardioprotective 效果。在现在的学习,在 VSMC 的增长上估计 ICI182,780 的效果,我们从老鼠主动脉孤立与或没有 ER 对手 ICI182,780 的有教养的 VSMC。3-(4,5-dimethylthiazol-2-yl ) 的结果 -2,5-diphenyltetrazolium 溴化物试金, bromodeoxyuridine 加入试金,可行房间计数,为增殖的房间的免疫化学的染色原子抗原(PCNA ) ,和流动 cytometry 决定的 S 阶段比率在 ICI182,780 治疗以后揭示了 VSMC 的显著增长。ICI182,780 显著地以一种剂量依赖者方式提高了房间生长(10 ? 810 ? 5 M ) 。而且, PCNA 积极的房间的数字和 VSMC 的 S 阶段前进与 ICI182,780 在治疗以后增加了。反向的 transcriptase 聚合酶链反应(RTPCR ) 和西方的污点分析证明在 VSMC 的 cyclin D1 的 mRNA 和蛋白质水平在 ICI182,780 的处理下面增加了。这些数据建议 ICI182,780 能支持 VSMC 的生长,它可能在心血管的系统上生产一些不利效果。 | Hong He Falin Yang Xin Wang Xianwei Zeng Qin Hu Jinghuan Huang Jinbo Feng | 2011 | Acta Biochimica et Biophysica Sinica2011,43,2: | 1 |
| 5 | Supersonic flow in the second-throat ejector-diffuser system 显示文摘 | Falin Chen Liu C F Yang J Y | 1994 | Journal of Spacecraft and Rockets1994,31,1: | 1 |
| 6 | Convective instability in ammonium chloride solution directionally solidified from below 显示文摘 | Chen Falin Lu J W Yang T L | 1994 | Journal of Fluid Mech1994,276,10: | 1 |
| 7 | Characteristics and mechanism of smart fluid for sweep-controlling during CO_(2) flooding显示文摘A smart response fluid was designed and developed to overcome the challenges of gas channeling during CO_(2)flooding in low-permeability,tight oil reservoirs.The fluid is based on Gemini surfactant with self-assembly capabilities,and the tertiary amine group serves as the response component.The responsive characteristics and corresponding mechanism of the smart fluid during the interaction with CO_(2)/oil were studied,followed by the shear characteristics of the thickened aggregates obtained by the smart fluid responding to CO_(2).The temperature and salt resistance of the smart fluid and the aggregates were evaluated,and their feasibility and effectiveness in sweep-controlling during the CO_(2)flooding were confirmed.This research reveals:(1)Thickened aggregates could be assembled since the smart fluid interacted with CO_(2).When the mass fraction of the smart fluid ranged from 0.05%to 2.50%,the thickening ratio changed from 9 to 246,with viscosity reaching 13 to 3100 mPas.As a result,the sweep efficiency in low-permeability core models could be increased in our experiments.(2)When the smart fluid(0.5%to 1.0%)was exposed to simulated oil,the oil/fluid interfacial tension decreased to the level of 1×10^(-2)mN/m.Furthermore,the vesicle-like micelles in the smart fluid completely transformed into spherical micelles when the fluid was exposed to simulated oil with the saturation greater than 10%.As a result,the smart fluid could maintain low oil/fluid interfacial tension,and would not be thickened after oil exposure.(3)When the smart fluid interacted with CO_(2),the aggregates showed self-healing properties in terms of shear-thinning,static-thickening,and structural integrity after several shear-static cycles.Therefore,this fluid is safe to be placed in deep reservoirs.(4)The long-term temperature and salt resistance of the smart fluid and thickened aggregates have been confirmed. | XIONG Chunming WEI Falin YANG Haiyang ZHANG Song DING Bin LEI Zhengdong ZHANG Deping ZHOU Qiang | 2023 | Petroleum Exploration and Development2023,50,3: | 0 |
| 8 | Raloxifene hydrochloride treatment leads to better outcomes than medroxyprogesterone acetate when paired with estrogen in ovariectomized cholesterol-fed rabbits显示文摘 | Caiyu Zeng Falin Yang Hong He Keqing Hu Xin Wang Qin Hu Jifu Li | 2014 | Acta Biochimica et Biophysica Sinica2014,46,12: | 0 |
| 9 | Challenges and improvement in management of neonates born to mothers with COVID-19 in China显示文摘Objective:China was the first country suffering from the SARS-CoV-2 pandemic and one of the countries with stringent mother-neonate isolation measure implemented.Now increasing evidence suggests that coronavirus disease 2019(COVID-19)should not be taken as an indication for formula feeding or isolation of the infant from the mother.Methods:We conducted a retrospective cohort study in 44 hospitals from 14 provinces in China to investigate the management of neonates whose mothers have confirmed or suspected COVID-19.In addition,65 members of Chinese Neonatologist Association(CNA)were invited to give their comments and suggestions on the clinical management guidelines for high-risk neonates.Results:There were 121 neonates born to 118 mothers suspected with COVID-19 including 42 mothers with SARS-CoV-2 positive results and 76 mothers with SARS-CoV-2 negative results.All neonates were born by caesarean section,isolated from their mothers immediately after birth and were formula-fed.Five neonates were positive for SARSCoV-2 at initial testing between 36 and 46 h after birth.Regarding the confusion on the clinical management guidelines,58.78%of the newborns were put into isolation,32.22%were subject to PCR tests,and 5.16%and 2.75%received breastfeeding and vaccination,respectively.Conclusion:The clinical symptoms of neonates born to mothers with confirmed SARS-CoV-2 were mild,though five neonates might have been infected in utero or during delivery.Given the favorable outcomes of neonates born to COVID-confirmed mothers,full isolation may not be warranted.Rather,separation of the mother and her newborn should be assessed on a case-by-case basis,considering local facilities and risk factors for adverse outcomes,such as prematurity and fetal distress. | Jie Yang Zhuxiao Ren Lingkong Zeng Shiwen Xia Lin Wang Jiayu Miao Zhe Zhao Chuanzhong Yang Xiuyong Cheng Huayan Zhang Yuanfang Zhu Li Liu Xirong Gao Bin Yi Zhenlang Lin Wei Liu Xiaoyu Zhou Benqing Wu Ling Chen Zhankui Li Xuefeng Zhang Wei Lu Lianhong Zhang Xiao Chen Xiaoyun Zhong Falin Xu Jinhui Wu Yong Ji Jiahua Pan Yanxiang Chen Carine Ronsmans Zhichun Feng | 2022 | Frigid Zone Medicine2022,2,2: | 0 |
| 10 | Efcient Algorithms for Cache-Throughput Analysis in Cellular-D2D 5G Network显示文摘In this paper,we propose a two-tiered segment-based Device-toDevice(S-D2D)caching approach to decrease the startup and playback delay experienced by Video-on-Demand(VoD)users in a cellular network.In the S-D2D caching approach cache space of each mobile device is divided into two cache-blocks.The rst cache-block reserve for caching and delivering the beginning portion of the most popular video les and the second cacheblock caches the latter portion of the requested video les‘fully or partially’depending on the users’video watching behaviour and popularity of videos.In this approach before caching,video is divided and grouped in a sequence of xed-sized fragments called segments.To control the admission to both cacheblocks and improve the system throughput,we further propose and evaluate three cache admission control algorithms.We also propose a video segment access protocol to elaborate on how to cache and share the video segments in a segmentation based D2D caching architecture.We formulate an optimisation problem and nd the optimal cache probability and beginning-segment size that maximise the cache-throughput probability of beginning-segments.To solve the non-convex cache-throughout maximisation problem,we derive an iterative algorithm,where the optimal solution is derived in each step.We used extensive simulations to evaluate the performance of our proposed S-D2D caching system. | Nasreen Anjum Zhaohui Yang Imran Khan Mahreen Kiran Falin Wu Khaled Rabie Shikh Muhammad Bahaei | 2021 | Computers, Materials & Continua2021,,5: | 0 |