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| 1 | Diagnosis and treatment of pancreas divisum: A literature review显示文摘Background:Pancreas divisum is a congenital embryological disease caused by a lack of fusion between the ventral and dorsal pancreatic ducts in the early stages of embryogenesis.Recurrent acute pancreatitis,chronic pancreatitis or chronic abdominal pain are the main clinical syndromes at presentation and occur in only 5%of the patients with pancreas divisum.This review aimed to discuss diagnosis and treatment strategies in patients with symptomatic pancreas divisum.Data sources:We report a literature review from 1990 up to January 2018 to explore the various diagnostic modalities and surgical techniques and results reported in the surgical treatment of pancreas divisum.Results:There are limited reports available on this topic in the literature.We analyzed and described the main indications in the treatment of pancreas divisum,focusing on surgical treatment and a discussion of the different approaches.Furthermore,we report the results from our experience in two cases of pancreas divisum treated by pancreatic head resection with segmental duodenectomy(the Nakao procedure).Conclusions:Pancreas divisum is a common pancreatic malformation in which only a few patients develop a symptomatic disease.Surgical treatment is needed in case of endoscopic drainage failure and in cases complicated with chronic pancreatitis and local complications.Many techniques,of greater or lesser complexity,have been proposed. | Valentina Ferri Emilio Vicente Yolanda Quijano Benedetto Ielpo Hipolito Duran Eduardo Diaz Isabel Fabra Riccardo Caruso | 2019 | Hepatobiliary & Pancreatic Diseases International2019，18，4： | 9 |
| 2 | Outcome in obscure gastrointestinal bleeding after capsule endoscopy显示文摘AIM: To investigate the clinical impact of capsule endoscopy(CE) after an obscure gastrointestinal bleeding(OGIB) episode, focusing on diagnostic work-up, followup and predictive factors of rebleeding. METHODS: Patients who were referred to Hospital del Mar(Barcelona, Spain) between 2007 and 2009 for OGIB who underwent a CE were retrospectively analyzed. Demographic data, current treatment with non-steroid antiinflammtory drugs or anticoagulant drugs, hemoglobin levels, transfusion requirements, previous diagnostic tests for the bleeding episode, as well as CE findings(significant or non-significant), work-up and patient out-comes were analyzed from electronic charts. Variables were compared by χ 2 analysis and Student t test. Risk factors of rebleeding were assessed by Log-rank test, Kaplan-Meier curves and Cox regression model. RESULTS: There were 105 patients [45.7% women, median age of 72 years old(interquartile range 56-79)] and a median follow-up of 326 d(interquartile range 123-641) included in this study. The overall diagnostic yield of CE was 58.1%(55.2% and 63.2%, for patients with occult OGIB and overt OGIB, respectively). In 73 patients(69.5%), OGIB was resolved. Multivariate analysis showed that hemoglobin levels lower than 8 g/dL at diagnosis [hazard ratios(HR) = 2.7, 95%CI: 1.9-6.3], patients aged 70 years and above(HR = 2.1, 95%CI: 1.2-6.1) and significant findings in CE(HR = 2.4, 95%CI: 1.1-5.8) were independent predictors of rebleeding. CONCLUSION: One third of the patients presented with rebleeding after CE; risk factors were hemoglobin levels < 8 g/dL, age ≥ 70 years or the presence of significant lesions. | Alex Caas-Ventura Lucia Márque Xavier Bessa Josep Maria DedeuDepartment of Gastroenterology Hospital del Mar Research Institute Pompeu Fabra University Marc Puigvehí Sílvia Delgado-Aros Ines Ana Ibáez Agustin Seoane Luis Barranco Felipe Bory Montserrat Andreu Begoa González-Suárez | 2013 | World Journal of Gastrointestinal Endoscopy2013，5，11： | 4 |
| 3 | Edible and Bio- degradable Starch Films: A Review显示文摘 | JIMENEZ A FABRA M J TALENS P | 2012 | Food and Bioprocess Technology2012，5，6： | 1 |
| 4 | Effect of Lipid Self-association on the Microstructure and Physical Proper- ties of Hydroxypropyl-methylcellulose Edible Films Contain- ing Fatty Acids显示文摘 | JIM NEZ A FABRA M J CHIRALT A | 2010 | Carbohydrate Polymers2010，82，3： | 1 |
| 5 | Culture of human hepatocytes from small surgical liver biopsies. Biochemical characterization and comparison with in vivo显示文摘 | M. José Gómez-Lechón Pilar López Teresa Donato Angel Montoya Amparo Larrauri Patricia Giménez Ramón Trullenque Ricardo Fabra José V. Castell | 1990 | In Vitro Cellular & Developmental Biology1990，，1： | 1 |
| 6 | Phosphate-solubilizing peanut associated bacteria: screening for plant growth-promoting activities显示文摘 | Tania Taurian María Soledad Anzuay Jorge Guillermo Angelini María Laura Tonelli Liliana Ludue?a Dayana Pena Fernando Ibá?ez Adriana Fabra | 2010 | Plant and Soil (-)2010，，1： | 1 |
| 7 | Effect of re - crystallization on tensile,optical and water vapour barrier properties of com starch films containing fatty acids 显示文摘 | Jimenez A Fabra M J Talens P | 2012 | Food Hydrocolloids2012，26，1： | 1 |
| 8 | Acute phase response of human hepatocytes: Regulation of acute phase protein synthesis by interleukin- 6显示文摘 | Gomez - lechon M J Fabra R | 1990 | Hepatology1990，12，： | 1 |
| 9 | Outcome of Patients With Ischemic Colitis: Review of Fifty-Three Cases显示文摘 | Carlos Medina M.D. Jaime Vilaseca Ph.D. Sebastián Videla Ph.D. Ramón Fabra M.D. J. R. Armengol-Miro Ph.D. J.-R. Malagelada Ph.D | 2004 | Diseases of the Colon & Rectum2004，，2： | 1 |
| 10 | Bulbocave mosus-reflex latencies and pudendal nerve SSEP compared to penile vascular testing in 669 patients with erectile failure and other sexual dysfunction显示文摘 | Fabra M Porst H | 1999 | Int J Impot Res1999，11，3： | 1 |
| 11 | Transforming growth factor beta stimulates mammary adenocarcinoma cell invasion and metastatic potential显示文摘 | Welch DR Fabra A Nakajima M | 1990 | Proc Natl Acad Sci USA1990，87，19： | 1 |
| 12 | Influence of calcium on tensile, optical and water vapour permeability properties of sodium caseinate edible films 显示文摘 | Fabra M J Talens P Chiralt A | 2010 | Journal of Food Engineering2010，96，： | 1 |
| 13 | Edible and biodegradable starch films: a review 显示文摘 | Jimrnez A Fabra M J Talens P | 2012 | Food & Bioprocess Technology2012，5，6： | 1 |
| 14 | Influence of the homogenization conditions and lipid self-association on properties of sodium caseinate based films containing oleic and stearic acids 显示文摘 | Fabra M J P6rez-Masit R Talens P | 2011 | Food Hydrocolloids2011，25，5： | 1 |
| 15 | Modeling electricity auctions显示文摘 | FabrA N yon der Fehr N Harbord D | 2002 | The ElectricityJournal2002，15，7： | 1 |
| 16 | Phase altimetry with dual polarization GNSS-R over sea ice显示文摘 | Fabra F Cardellach E Rius A | 2012 | IEEE Transactions on Geoscience and Remote Sensing2012，50，6： | 1 |
| 17 | Alterations in root colonization and nodC gene induction in the peanut-rhizobia interaction under acidic conditions显示文摘 | Angelini J Castro S Fabra A | 2003 | Plant Physiology and Biochemistry2003，41，3： | 1 |
| 18 | Outcome of Patients With Ischemic Colitis: Review of Fifty-Three Cases显示文摘 | Carlos Medina M.D. Jaime Vilaseca Ph.D. Sebastián Videla Ph.D. Ramón Fabra M.D. J. R. Armengol-Miro Ph.D. J.-R. Malagelada Ph.D | 2004 | Diseases of the Colon & Rectum2004，，2： | 1 |
| 19 | Metastatic colonization requires the repression of the epithelial-mesenchymal transition inducer Pn'x-1 显示文摘 | Ocafia OH C6rcoles R Fabra A | 2012 | Cancer Cell2012，22，6： | 1 |
| 20 | Effect of Fatty acids and beeswax addition on properties of sodium caseinate dispersions and films显示文摘 | Fabra M J Jim e nez A Atar e s L | 2009 | Biomacromolecules2009，10，6： | 1 |
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