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| 1 | Consequences of Helicobacter pylori infection in children显示文摘Although evidence is emerging that the prevalence of Helicobacter pylori (H. pylori) is declining in all age groups, the understanding of its disease spectrum continues to evolve. If untreated, H. pylori infection is lifelong. Although H. pylori typically colonizes the hu-man stomach for many decades without adverse con-sequences, children infected with H. pylori can manifest gastrointestinal diseases. Controversy persists regarding testing (and treating) for H. pylori infection in children with recurrent abdominal pain, chronic idiopathic thrombocytopenia, and poor growth. There is evidence of the role of H. pylori in childhood iron deficiency anemia, but the results are not conclusive. The possibility of an inverse relationship between H. pylori and gastroesophageal reflux disease, as well as childhood asthma, remains a controversial question. A better understanding of the H. pylori disease spectrum in childhood should lead to clearer recommendations about testing for and treating H. pylori infection in children who are more likely to develop clinical sequelae. | Lucia Pacifico Caterina Anania John F Osborn Flavia Ferraro Claudio Chiesa | 2010 | World Journal of Gastroenterology2010，16，41： | 11 |
| 2 | Value of a newly sequenced bacterial genome显示文摘Next-generation sequencing(NGS) technologies have made high-throughput sequencing available to medium- and small-size laboratories, culminating in a tidal wave of genomic information. The quantity of sequenced bacterial genomes has not only brought excitement to the field of genomics but also heightened expectations that NGS would boost antibacterial discovery and vaccine development. Although many possible drug and vaccine targets have been discovered, the success rate of genome-based analysis has remained below expectations. Furthermore, NGS has had consequences for genome quality, resulting in an exponential increase in draft(partial data) genome deposits in public databases. If no further interests are expressed for a particular bacterial genome, it is more likely that the sequencing of its genome will be limited to a draft stage, and the painstaking tasks of completing the sequencing of its genome and annotation will not be undertaken. It is important to know what is lost when we settle for a draft genome and to determine the 'scientific value' of a newly sequenced genome. This review addresses the expected impact of newly sequenced genomes on antibacterial discovery and vaccinology. Also, it discusses the factors that could be leading to the increase in the number of draft deposits and the consequent loss of relevant biological information. | Eudes GV Barbosa Flavia F Aburjaile Rommel TJ Ramos Adriana R Carneiro Yves Le Loir Jan Baumbach Anderson Miyoshi Artur Silva Vasco Azevedo | 2014 | World Journal of Biological Chemistry2014，5，2： | 7 |
| 3 | An MMIC pulse generator using dual nonlinear transmission lines 显示文摘 | KINTIS M XING L FLAVIA F | 2007 | IEEE Microwave and Wireless Components Letters2007，17，6： | 1 |
| 4 | Lipoic acid: a unique antioxidant in the detoxification of activated oxygen species 显示文摘 | FLAVIA N I MIKE F Q CRISTINA S | 2002 | Plant Physiol Biochem2002，40，： | 1 |
| 5 | Application of electronic nose technology for the detection of fungal contamination in library paper 显示文摘 | Olinda C Flavia P Con'ado F | 2004 | Int Biodet Biodegr2004，54，： | 1 |
| 6 | Electronic nose for the early detection of moulds in libraries and archives显示文摘 | Flavia P Corrado F O1inda C | 2004 | Indoor and Built Environment2004，13，5： | 1 |
| 7 | Electronic Nose for the Early Detection of Moulds in Libraries and Archives显示文摘 | Flavia P Corrado F Olinda C | 2004 | Indoor and Built Environment2004，13，5： | 1 |
| 8 | Direct anal ysis of antarctic krill by slurry sampling: determination of copper, iron, manganese and zinc by flame atomic absorption spectrometry显示文摘 | FLAVIA L A PATRICIA S SILVIA F | 2000 | Journal of the Brazilian Chemical Society2000，11，4： | 1 |
| 9 | A versatile splitless injection GC-FID method for the determination of mineral oil paraffins in vegetable oils and dried fruit显示文摘 | DENNIS F ALBERTO P FLAVIA G | 2010 | Food Control2010，21，8： | 1 |
| 10 | Adulteration of Diesel/biodiesel Blends by Ve-getable Oil as Determined by Fourier Transform(FT)near Infrared Spectrometry and FT-Raman Spectroscopy显示文摘 | Flavia C C O Christian R R B Hugo F R | 2007 | Analytica Chimica Acta2007，587，2： | 1 |
| 11 | Conglomerated masses of silicosis in sandhlasters: High-resolution CT fndings显示文摘 | EDSON M ANGELA F FLAVIA S | 2006 | European Journal of Radiology2006，59，： | 1 |
| 12 | IL-6 -deficient mice show impaired inflammatory response in a model of myosin induced experimental myositis 显示文摘 | FLAVIA S MANNELLA F MARINO M | 2006 | Journal of Neuroimmunology2006，176，： | 1 |
| 13 | Conglomerated masses of silicosis in sandblastersz High-resolution CT ndings显示文摘 | EDSON M ANGELA F FLAVIA S | 2006 | European Journal of Radiology2006，59，： | 1 |
| 14 | Lipoic acid:a unique antioxidant in the detoxification of activated oxygen species显示文摘 | Flavia N I Mike F Q Cristina S | 2002 | Plant Physiol Biochem2002，40，： | 1 |
| 15 | Aging Response of the Ti-35Nb-7Zr-5Ta and Ti-35Nb-7Ta Alloys显示文摘 | Peterson L F Flavia F C Sandra A S | 2007 | Journalof Alloys and Compounds2007，，433： | 1 |
| 16 | Lipoic acid: a unique antioxi- dant in the detoxification of activated oxygen species显示文摘 | Flavia N I Mike F Q Cristina S | 2002 | Plant Physiology and Biochemistry2002，40，： | 1 |
| 17 | Dimethyl adipate hydrogenation at presence of Pt based catalysts显示文摘 | Flavia C A F Elizabete J Wagner A C | 2005 | Catalysis Today2005，，： | 1 |
| 18 | Evaluation of an adsorptionelution method for detection of astrovirus and norovirus in environmental waters显示文摘 | Matias V Flavia G Tulio F | 2009 | J Virol Methods2009，156，1： | 1 |
| 19 | Electronic nose for the ear- ly detection of moulds in libraries and archives显示文摘 | Flavia P Corrado F Olinda C | 2004 | Indoor and Built Environment2004，13，5： | 1 |
| 20 | Aging response of the Ti-35Nb-7Zr-5Ta and Ti-35Nb-7Ta alloys 显示文摘 | PETERSON L F FLAVIA F C SANDRA A S | 2007 | Journal of Alloys and Compounds2007，433，12： | 1 |
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