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| 1 | 最新AD研究用诊断标准:IWG-2标准显示文摘在过去的8年中,国际工作组织(IWG)和美国国立老化研究院-阿尔茨海默协会(NIA-AA)建立了阿尔茨海默病(AD)诊断标准,它能更好地定义AD的临床表型,整合了生物标记物于诊断流程中,并覆盖了疾病的全程。本意见书充分地权衡了IWG标准的优缺点,建议改进诊断框架。依据这些改进,AD的诊断变得简单,只要有恰当的AD临床表型(典型或不典型)和与AD的病理相一致的病理生理学生物标志物出现。我们认为疾病的下游的定位性生物标志,如容积性磁共振成像(MRI)和氟脱氧葡萄糖-正电子发射型计算机断层成像(FDG-PET)等,适合更好地测量和监测疾病过程。本文还详述了非典型性AD、混合性AD和AD临床前期的特异诊断标准。 | 陈刚 曹雯炜 俞羚 糜建华 Dubois B Feldman HH Jacova C Hampel H Molinuevo JL Blennow K DeK osky ST Gauthier S Selkoe D Bateman R Cappa S Crutch S Engelborghs S Frisoni GB Fox NC Galasko D Habert MO Jicha GA Nordberg A Pasquier F Rabinovici G Robert P Rowe C Salloway S Sarazin M Epelbaum S de Souza LC Vellas B Visser PJ Schneider L Stern Y Scheltens P Cummings JL | 2014 | 神经病学与神经康复学杂志2014，11，3： | 31 |
| 2 | 慢性肾脏病中的炎症和动脉硬化:慢性肾功能不全队列研究中的发现显示文摘慢性肾脏病(chronic kidney disease,CKD)和动脉硬化程度与心血管病发病率和死亡率增加相关。目前认为炎症在动脉硬化发展中发挥作用,而CKD被认为是一种促炎症反应的状态。CKD患者的动脉僵硬度增加,横断面数据提示CKD中增多的炎症标志物与较高动脉僵硬度值相关。 | Peyster E Chen J Feldman HI Go AS Gupta J Mitra N Pan Q Porter A Rahman M Raj D Reilly M Wing MR Yang W Townsend RR 陈云 叶鹏 | 2017 | 中华高血压杂志2017，25，11： | 12 |
| 3 | Coronary artery bypass graft surgery versus percutaneous coronary intervention in patients with three-vessel disease and left main coronary disease: 5-year follow-up of the randomised, clinical SYNTAX trial显示文摘 | Friedrich W Mohr Marie-Claude Morice A Pieter Kappetein Ted E Feldman Elisabeth St?hle Antonio Colombo Michael J Mack David R Holmes Marie-angèle Morel Nic Van Dyck Vicki M Houle Keith D Dawkins Patrick W Serruys | 2013 | The Lancet . 2013 (9867)2013，，9867： | 2 |
| 4 | The design and fabrication of a 40 cm diameter,SiC coated,normal incidence telescope and spectrometer显示文摘 | Stephan R McCandliss Mel E Martinez Paul D Feldman | 1994 | SPIE1994，2011，： | 1 |
| 5 | Latent heat storage in concrete Ⅱ显示文摘 | Hawes D W Banu D Feldman D | 1990 | Solar Energy Mater1990，21，： | 1 |
| 6 | Coxsackievirus B3 induces T regulatory cells, which inhibit cardiomyopathy in tumor necrosis factor-α transgenic mice显示文摘 | H uber SA Feldman AM Sartini D | 2006 | Circ Res2006，99，10： | 1 |
| 7 | Inhibition of prostate cancer growth by vitamin D : Regulation of target gene expression 显示文摘 | KRISHNAN AV PEEHL DM FELDMAN D | 2003 | J Cell Biochem2003，88，2： | 1 |
| 8 | Global elemental maps of the Moon: The lunar prospector gamma ray spectromet er显示文摘 | Lawrence D J Feldman W C Barraclough B L | 1998 | Science1998，281，： | 1 |
| 9 | Evaluation of thermal storage as latent heat in phase change material wall- board by differential scanning calorimetry and large scale thermal testing 显示文摘 | Banu D Feldman D Hawes D | 1998 | Thermochimica Acta1998，317，1： | 1 |
| 10 | Obtaining an energy storing building material by direct incorporation of an organic phase change material in gypsum wallboard显示文摘 | Feldman D Banu D Hawes D | 1991 | Solar Energy Materials1991，22，23： | 1 |
| 11 | Clinical determination of myocardial vs load effects of OPC-18790,a novel intravenous agent for the treatment of patients with congestive heart failure显示文摘 | Feldman M D Haber H L Wu C C | 1993 | Circulation1993，88，42： | 1 |
| 12 | 显示文摘 | Feldman Y Wasserman E Srolovitz D J | 1995 | Science1995，267，： | 1 |
| 13 | Decreased interferon-a production in HIV-infected patients correlates with numerical and functional deficiencies in circulating type-dendritic cell precursors显示文摘 | Feldman S Stein D Amrute S | 2001 | Clinical Innunology2001，101，： | 1 |
| 14 | A projection approach to ro- bust adaptive beamforming显示文摘 | Feldman D D Griffit hs L J | 1994 | IEEE Transactions on Signal Processing1994，42，4： | 1 |
| 15 | Develop and application of or- ganic phase change mixtures in thermal storage gypsum wall- board显示文摘 | Feldman D Banu D Hawes D W | 1995 | Solar Energy Materials and Solar Cells1995，36，2： | 1 |
| 16 | The role of vitamin D in reducing cancer risk and progression 显示文摘 | Feldman D Krishnan AV Swami S | 2014 | Nat Rev Cancer2014，14，5： | 1 |
| 17 | Absorption of phase change materials in concrete显示文摘 | Hawes D W Feldman D | 1992 | Solar Energy Mater Solar Cells1992，27，： | 1 |
| 18 | A phase 2 clinical trial of deforolimus (AP23573, MK-8669), a novel mammalian target of rapamycin inhibitor, in patients with relapsed or refractory hematologic malignancies显示文摘 | Rizzieri D A Feldman E DiPersio J F | 2008 | Clin Cancer Res2008，14，9： | 1 |
| 19 | Absorption of phase change materials in concrete显示文摘 | Hawes D W Feldman D | 1992 | Solar Energy Materials and Solar Cells1992，27，2： | 1 |
| 20 | Population structure,fitness surfaces,and linkage in the shifting balance process显示文摘 | BERGMAN A GOLDSTEIN D B FELDMAN M W | 1995 | Genetical Research1995，66，： | 1 |
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