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| 1 | Starting glargine in insulin-nave type 2 diabetic patients based on body mass index is safe显示文摘AIM:To evaluate the safety of four insulin titration algorithms in a homogeneous population of insulin-na ve type 2 diabetic patients.METHODS:We conducted a 24-wk,open,single-center study with 92 insulin-na ve type 2 diabetes patients who failed treatment with one or two oral drugs.The patients were randomized to one of the four following algorithms:LANMET(n=26)and LANMET PLUS(n=22)algorithms,whose patients received a fixed initial insulin dose of 10 U,and DeGold(n=23)and DeGold PLUS(n=21)algorithms,whose patients’initial insulin dose was based on their body mass index(BMI).In addition,patients in the PLUS groups had their insulin titrated twice a week from 2 to 8 U.In the other two groups,the titration was also performed also twice a week,but in a fixed increments of 2 U.The target fasting glucose levels for both groups was 100 mg/dL.RESULTS:There was no significant difference in efficacy parameters.There was no significant difference when comparing moderate hypoglycemia events in algorithms starting with a 10 U fixed dose and algorithms based on BMI.However,there was a significant increase in moderate hypoglycemia events among the PLUS treated patients when the LANMET and DeGold algorithms were compared with the 2 fast-titration PLUS algorithms.We observed 12 hypoglycemia events in the first group,which corresponded to 0.94 events/patient per year,and we observed 42 events in the second group,which corresponded to 2.81 events/patient per year(P<0.037).No further significant differences were observed when other comparisons between the algorithms were carried out.CONCLUSION:Starting insulin glargine based on BMI is safe,but fast titration algorithms increase the risk of moderate hypoglycemia. | Denise R Franco Juliana Baptista Fatima RM Abreu Risoneide B Batista Freddy G Eliaschewitz | 2014 | World Journal of Diabetes2014，5，1： | 2 |
| 2 | Recovery of heat-injured Listeria innocua显示文摘 | FATIMA A MILLER T R S PAULA T | 2006 | International Journal of Food Microbiology2006，112，： | 1 |
| 3 | An agenda-based framework for multi-issue negotiation显示文摘 | Fatima S S Wooldridge M Jennings N R | 2004 | Artificial Intelligence2004，152，1： | 1 |
| 4 | Long noncoding RNAs in development and cancer:potential biomarkers and therapeutic targets显示文摘 | FATIMA R AKHADE V S PAL D | 2015 | Mol Cell Ther2015，3，： | 1 |
| 5 | Attitudes towards seeking professional psychological help:what really counts for United arab emirates University students显示文摘 | Al-Darmaki Fatima R | | 0，，05： | 1 |
| 6 | Pulmonary artery diameters in healthy fetuses from 19 to 40 weeks' gestation显示文摘 | Ruano R de Fatima Yukie Maeda M Niigaki JI | 2007 | J Ultrasound Med2007，26，3： | 1 |
| 7 | Shelf life of shrimp (Penaeus merguiensis) stored in ice and partially frozen显示文摘 | Fatima R Khan M A Qadri R B | 1988 | J Sci Food Agric1988，42，： | 1 |
| 8 | An agenda- based framework fo multi-issue negotiation 显示文摘 | FATIMA S S WOOLDRIDGE M JENNINGS N R | 2004 | Artificial Intelligence2004，152，1： | 1 |
| 9 | Control of the chemical structure of perhydrous coals: FTIR and Py-GC/MS investigation显示文摘 | Maria J I Jose C R Fatima L D | 2002 | Journal of Analytical and Applied Pyrolysis2002，62，1： | 1 |
| 10 | An Agenda-Based Framework for Multi-Issue Negotiation显示文摘 | Fatima S S Wooldridge M Jennings N R | 2004 | Aritficial Intelligence2004，152，1： | 1 |
| 11 | Pigmentary demarcation lines over the face显示文摘 | Somani VK Fatima R Sita VNVL | 2004 | Indian J Dermatol Venereol Leprol2004，70，6： | 1 |
| 12 | Native-like tertiary struc- ture in the Mucor miehei lipase molten globule state ob- tained at low pH 显示文摘 | Fatima S Ahmad B Khan R H | 2007 | IUBMB Life2007，59，3： | 1 |
| 13 | Remarkable effect of Co and Mn on the activity of Fe3-xMxO4 promoted oxidation of organic contaminants in aqueous medium with H2O2 显示文摘 | Costa R C C de Fatima M Lelis F Oliveira L C A Fabrls J D Ardisson J D Rios R R V A Silva C N Lago R M | 2003 | Catal Comm2003，4，10： | 1 |
| 14 | Readmission rates for Hispanic Medicare beneficiaries with heart failure and acute myocardial infarction 显示文摘 | Fatima R Joynt KE Lenny L | 2011 | Am Heart J2011，162，2： | 1 |
| 15 | A study of bladderdysfunction in women with type 2 diabetes mellitus显示文摘 | Karoli R Bhat S Fatima J | 2014 | IndianJ Endocrinol Metab2014，18，4： | 1 |
| 16 | An agenda-based framework for muhi-ssue negotiation显示文摘 | Fatima S S Wooldridge M Jennings N R | 2004 | Artificail Intelligece2004，152，1： | 1 |
| 17 | An agenda-based framework for multi-issue negotiation 显示文摘 | Fatima S Wooldridge M Jennings N R | 2004 | Artificial Intelligence (S0004-3702)2004，152，1： | 1 |
| 18 | An agenda-based framework for multi-issue negotiation显示文摘 | Fatima S S Wooldridge M Jennings N R | 2004 | Artificial Intelligence2004，152，： | 1 |
| 19 | Determining the risk factors and prevalence of osteoporosis using quantitative ultrasonography in Pakistani adult women显示文摘 | Fatima M Nawaz H Kassi M Rehman R Kasi PM Kassi M | 2009 | Singapore Med J2009，50，1： | 1 |
| 20 | Optimal negotiation strategies for agents with incomplete information显示文摘 | Fatima S S Wooldridge M Jennings N R | 2002 | Intelligent Agents Ⅷ Springer-Verlag Lecture Notes2002，03，： | 1 |
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