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| 1 | Pancreatic endometrial cyst mimics mucinous cystic neoplasm of the pancreas显示文摘Pancreatic cysts include a variety of benign, premalignant, and malignant lesions. Endometrial cysts in the pancreas are exceedingly rare lesions that are difficult to diagnose pre-operatively. This report describes the findings in a 43-year-old patient with a recent episode of acute pancreatitis who presented with a large cyst in the tail of the pancreas. Imaging demonstrated a loculated pancreatic cyst, and cyst fluid aspiration revealed an elevated amylase and carcinoembryonic antigen. The patient experienced an interval worsening of abdominal pain, fatigue, diarrhea, and a 15-pound weight loss 3 mo after the initial episode of pancreatitis. With concern for a possible pre-malignant lesion, the patient underwent a laparoscopic distal pancreatectomy with splenectomy, which revealed a 16cm×12cm×4cm lesion. Final histopathology was consistent with an intra-pancreatic endometrial cyst. Here we discuss the overlapping imaging and laboratory features of pancreatic endometrial cysts and mucinous cystic neoplasms of the pancreas. | Michael A Mederos Nicole Villafane Sadhna Dhingra Carlos Farinas Amy Mc Elhany William E Fisher George Van Buren II | 2017 | World Journal of Gastroenterology2017，23，6： | 7 |
| 2 | Cancer stem cells in colorectal cancer from pathogenesis to therapy: Controversies and perspectives显示文摘Colorectal cancer remains one of the most common and lethal malignancies worldwide despite the use of various therapeutic strategies.A better understanding of the mechanisms responsible for tumor initiation and progression is essential for the development of novel,more powerful therapies.The traditional,so-called'stochastic model'of tumor development,which assumes that each cancer cell is tumorigenic,has been deeply challenged during the past decade by the identification of cancer stem cells(CSCs),a biologically distinct subset of cells within the bulk of tumor mass.This discovery led to the development of the hierarchical model of tumorigenesis which assumes that only CSCs have the ability to initiate tumor growth,both at primary and metastatic sites.This model implies that the elimination of all CSCs is fundamental to eradicate tumors and that failure to do so might be responsible for the occurrence of relapses and/or metastases frequently observed in the clinical management of colorectal cancer patients.Identification and isolation of CSCs is essential for a better understanding of their role in the tumorigenetic process and for the development of CSC-specific therapies.Several methods have been used for this purpose and many efforts have been focused on the identification of specific CSC-surface markers.This review provides an overview of the proposed roles of CSC in human colorectal tumorigenesis focusing on the most important molecules identified as CSC-specific markers in colorectal cancer and on the potential strategies for the development of CSC-targeted therapy. | Caterina Fanali Donatella Lucchetti Marisa Farina Maddalena Corbi Valerio Cufino Achille Cittadini Alessandro Sgambato | 2014 | World Journal of Gastroenterology2014，20，4： | 7 |
| 3 | Nitrogen Release from Slow-Release Fertilizers in Soils with Different Microbial Activities显示文摘Soil microbial activity is recognized as an important factor affecting nitrogen (N) release from slow-release fertilizers. However,studies on the effect of size and activity of soil microflora on fertilizer degradation have provided contrasting results. To date, no clear relationships exist between soil microbial activity and the release of N from slow-release fertilizers. Hence, the aim of this study was to better understand such relationships by determining the release of N from three slow-release fertilizers in soils with different microbial activities. Soils were amended with urea-formaldehyde (UF), isobutylidene diurea (IBDU), and crotonylidene diurea (CDU). Urea, a soluble fertilizer, was used as the control. Fertilized soil samples were placed in a leaching system, and the release of N was determined by measuring ammonium-N and nitrate-N concentrations in leachates during 90 d of incubation. Non-linear regression was used to fit N leaching rate to a first-order model. In all the treated soils, N was released in the order: urea (89%–100%) > IBDU (59%–94%) >UF (46%–73%) > CDU (44%–56%). At the end of incubation, N released from CDU did not differ (P > 0.05) among soils. On the contrary, UF and IBDU released significantly lower (P < 0.05) amounts of N in the soil with higher microbial activity and lower pH.The rate constant (K_0) for UF was lower (P < 0.05) in the soil with lower pH. Taken together, our results indicated that soil microbial size and microbial activity had a marginal effect on fertilizer mineralization. | Pierfrancesco NARDI Ulderico NERI Giovanni DI MATTEO Alessandra TRINCHERA Rosario NAPOLI Roberta FARINA Guntur V. SUBBARAO Anna BENEDETTI | 2018 | Pedosphere2018，28，2： | 4 |
| 4 | 课前指导与补充指导对学生网络学习的影响显示文摘马来西亚开放大学(OUM)90%以上的学生为在职人员。这些成年学生离开学校至少已经5年,而且大多数人的数学基础不好。因此,仅是在线学习加少量面授辅导的教学模式对他们来说还不能完全解决学习困难。学校试用了'课前指导工作室'与'补充指导'的教学方法,探讨了这一方法对学员的在线参与程度及考试结果的影响,运用源于探究团体模式的34项量表对在线论坛的内容进行了分析,结果表明,学员参加工作室与否同他们的期末考试成绩有很大关系。参加指导老师工作室及补充指导的学员与那些参加指导老师常规指导的学员相比,前者的在线参与程度及期末考试的平均分都存在着很大的差异。两组学员的数学探究团体模式平均分表明,两组学员在教学存在和认知存在方面有差异,但在社会存在方面基本相同。 | Richard Ng Abtar Kaur Siti Farina Sheikh Mohamed Latifah Abdol Latif Ramli Bahroom 王惠云 | 2009 | 天津电大学报2009，13，2： | 3 |
| 5 | Ubiquitous Activation of Ras and Jak/Stat Pathways in Human HCC显示文摘 | Diego F. Calvisi Sara Ladu Alexis Gorden Miriam Farina Elizabeth A. Conner Ju–Seog Lee Valentina M. Factor Snorri S. Thorgeirsson | 2006 | Gastroenterology2006，，4： | 3 |
| 6 | Channel Mismatching in Sidelobe Canceler: Limitations and Remedies显示文摘After a brief recall of the Sidelobe Canceler (SLC) working principle, including the derivation of a general formula for the Cancellation Ratio (CR), the effects of channel mismatching are investigated. In particular, curves providing CRvalues as a function of amplitude and phase channel mismatching, radar bandwidth, and jammer direction of arrival (JDOA) are provided for the cases of one and two auxiliary antennas. Subsequently, a time -space processor for performance restoration is analyzed in detail. In addition to the above mentioned quantities, the attainable CR value is expressed as a function of the space-time processor parameters. The contribution of the paper is related to the derivation of a number of mathematical equations of CR for several cases of practical interest for the radar engineer. In addition, several curves are presented to assist design of SLC systems. | A. Farina and A. ProtopapaRadar Dpt Selenia S. p. A., Via Tiburtina,Km. 12,400-00131 Rome, Italy | 1992 | Journal of Systems Engineering and Electronics1992，3，3： | 2 |
| 7 | 行卵母细胞单精子显微注射且年龄≥40岁的患者使用促性腺激素释放激素类似物进行控制性超促排卵治疗短期或长期方案的比较显示文摘To determine whether the short or long protocol for controlled ovarian hyperstimulation works better in older patients undergoing IVF. Design: Controlled, randomized study. Setting: A single private IVF center. Patient(s): Two hundred twenty infertile women aged ≥ 40 years undergoing IVF.Intervention(s): At their first IVF cycle, the women were randomized into two stud groups according to a computer-generated number sequence: 110 patients were treated with a long protocol, and the other 110 were treated with a short protocol for controlled ovarian hyperstimulation. Main Outcome Measure(s): Days of stimulation, E2 level at the day of hCG administration, amount of FSH administered, number of oocytes collected, number of embryos obtained, pregnancy rate, implantation rate. Result(s): Patients treated with a long protocol showed a significantly higher number of oocytes retrieved, a higher number of embryos obtained, and a higher pregnancy rate, both for cycle and transfer, compared with the short-protocol patients. The other parameters evaluated did not show any statistically significant differences. Conclusion(s): Our study showed that the long protocol performed better than the short protocol in older women. Our findings demonstrated that flare-up in older women might be detrimental. | Sbracia M. Farina A. Poverini R. 张剑萍(译) | 2006 | 世界核心医学期刊文摘(妇产科学分册)2006，2，1： | 2 |
| 8 | Effect of joint angle on EMG variables in leg and thigh muscles显示文摘 | Dario Farina Roberto Merletti Marisa Nazzaro | 2001 | IEEE Engineering in Medicine and Biology2001，20，6： | 2 |
| 9 | Detection with High Resolution Radar: Advanced Topics & Potential Applications显示文摘In a previous companion paper [1], the potential advantages of high resolution radar for improved target detection were introduced. In particular, the concept of shaping both the transmitted waveform and the receiving processor in accordance to the expected target down-range profile was highlighted and performance predictions were provided. In this paper, we present and evaluate an adaptive scheme devised to on-line estimate the target profile, in order to overcome a limited a-priori knowledge. In addition, we introduce a more general model of target impulse response, based on a statistical description, and we discuss the corresponding processing scheme and detection performance. | Alfonso Farina Flavio A.Studer ALENIA S.p.A. | 1992 | Journal of Systems Engineering and Electronics1992，3，1： | 2 |
| 10 | Mechanisms involved in selecting and maintaining neuroblastoma cancer stem cell populations, and perspectives for therapeutic targeting显示文摘Pediatric neuroblastomas(NBs)are heterogeneous,aggressive,therapy-resistant embryonal tumours that originate from cells of neural crest(NC)origin and in particular neuroblasts committed to the sympathoadrenal progenitor cell lineage.Therapeutic resistance,post-therapeutic relapse and subsequent metastatic NB progression are driven primarily by cancer stem cell(CSC)-like subpopulations,which through their self-renewing capacity,intermittent and slow cell cycles,drug-resistant and reversibly adaptive plastic phenotypes,represent the most important obstacle to improving therapeutic outcomes in unfavourable NBs.In this review,dedicated to NB CSCs and the prospects for their therapeutic eradication,we initiate with brief descriptions of the unique transient vertebrate embryonic NC structure and salient molecular protagonists involved NC induction,specification,epithelial to mesenchymal transition and migratory behaviour,in order to familiarise the reader with the embryonic cellular and molecular origins and background to NB.We follow this by introducing NB and the potential NC-derived stem/progenitor cell origins of NBs,before providing a comprehensive review of the salient molecules,signalling pathways,mechanisms,tumour microenvironmental and therapeutic conditions involved in promoting,selecting and maintaining NB CSC subpopulations,and that underpin their therapy-resistant,self-renewing metastatic behaviour.Finally,we review potential therapeutic strategies and future prospects for targeting and eradication of these bastions of NB therapeutic resistance,post-therapeutic relapse and metastatic progression. | Antonietta Rosella Farina Lucia Annamaria Cappabianca Veronica Zelli Michela Sebastiano Andrew Reay Mackay | 2021 | World Journal of Stem Cells2021，13，7： | 2 |
| 11 | Lovastatin alters cytoskleton organization and inhibits experimental metastasis of mammary carcinoma cells显示文摘 | Farina HG Bublik DR Alonso DF | 2002 | Clin-Exp-Metastasis2002，19，6： | 2 |
| 12 | Functional study of the transplanted kidney with power Doppler US and time/intensity curves 显示文摘 | Farina R Pennisi F La Rosa M | 2007 | Radiol Med2007，112，： | 1 |
| 13 | A MAPK pathway mediates ethylene signaling in plants 显示文摘 | Farina O Wilfried R Dauid L | 2003 | EMBO J2003，22，6： | 1 |
| 14 | Cramer-Rao Bound for Nonlinear Filtering With Pd<1 and Its Application to Target Tracking 显示文摘 | Farina A Ristic B Timmoneri L | 2002 | IEEE Transactions on Signal Processing2002，，50： | 1 |
| 15 | Nonlinear surface EMG analysis to detect changes of motor unit conduction velocity and synchronization显示文摘 | FARINA D FATTORINI L FELICI F | 2002 | J Appl Physiol2002，93，： | 1 |
| 16 | Short versus long gonadotropin-releasing hormone analogue suppression protocols for superovulation in patients ≥ 40 years old undergoing intracytoplasmic sperm injection显示文摘 | Sbracia M Farina A Pocerini R | 2005 | Fertil Steril2005，84，3： | 1 |
| 17 | Fatigue strength: effeet of welding type and joint design executed in Ti-6A1-4V structures显示文摘 | Pantoja JM Farina AP Vaz LG | 2012 | Gerodontology2012，29，2： | 1 |
| 18 | Dynamics of infection and immunity in a dairy cattle population undergoing an eradication pro- gramme for Infectious bovine rhinotracheitis (IBR) 显示文摘 | Nardelli S Farina G Lucehini R | 2008 | Prey Vet Med2008，85，12： | 1 |
| 19 | Detection algorithms to discriminate between radar targets and ECM signals显示文摘 | Bandiera F Farina A Orlando D | 2010 | IEEE Transactions on Signal Processing2010，58，12： | 1 |
| 20 | Antimicro- bial susceptibility of Escherichia coli 0157 and other enterohaemorrhagic Escherichia coli iso- lated in Italy显示文摘 | Farina C Goglio A Conedera G | 1996 | European Journal of Clinical Microbiology1996，15，4： | 1 |
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