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| 1 | China Patient-centered Evaluative Assessment of Cardiac Events Prospective Study of Acute Myocardial Infarction: Study Design显示文摘 | Rachel P Dreyer Xi Li Xue Du Nicholas S Downing Li Li Hai-Bo Zhang Fang Feng Wen-Chi Guan Xiao Xu Shu-Xia Li Zhen-Qiu Lin Frederick A Masoudi John A Spertus Harlan M Krumholz Li-Xin Jiang | 2016 | Chinese Medical Journal2016，，1： | 13 |
| 2 | Projection micro stereolithography based 3D printing and its applications显示文摘Projection micro stereolithography(PμSL)is a high-resolution(up to 0.6μm)3D printing technology based on area projection triggered photopolymerization,and capable of fabricating complex 3D architectures covering multiple scales and with multiple materials.This paper reviews the recent development of the PμSL based 3D printing technologies,together with the related applications.It introduces the working principle,the commercialized products,and the recent multiscale,multimaterial printing capability of PμSL as well as some functional photopolymers that are suitable to PμSL.This review paper also summarizes a few typical applications of PμSL including mechanical metamaterials,optical components,4D printing,bioinspired materials and biomedical applications,and offers perspectives on the directions of the further development of PμSL based 3D printing technology. | Qi Ge Zhiqin Li Zhaolong Wang Kavin Kowsari Wang Zhang Xiangnan He Jianlin Zhou Nicholas X Fang | 2020 | International Journal of Extreme Manufacturing2020，2，2： | 11 |
| 3 | Breaking the barriers: advances in acoustic functional materials显示文摘Acoustics is a classical field of study that has witnessed tremendous developments over the past 25 years.Driven by the novel acoustic effects underpinned by phononic crystals with periodic modulation of elastic building blocks in wavelength scale and acoustic metamaterials with localized resonant units in subwavelength scale, researchers in diverse disciplines of physics, mathematics, and engineering have pushed the boundary of possibilities beyond those long held as unbreakable limits. More recently, structure designs guided by the physics of graphene and topological electronic states of matter have further broadened the whole field of acoustic metamaterials by phenomena that reproduce the quantum effects classically. Use of active energy-gain components, directed by the parity–time reversal symmetry principle,has led to some previously unexpected wave characteristics. It is the intention of this review to trace historically these exciting developments, substantiated by brief accounts of the salient milestones. The latter can include, but are not limited to, zero/negative refraction, subwavelength imaging, sound cloaking, total sound absorption, metasurface and phase engineering, Dirac physics and topology-inspired acoustic engineering, non-Hermitian parity–time synthetic active metamaterials, and one-way propagation of sound waves. These developments may underpin the next generation of acoustic materials and devices, and offer new methods for sound manipulation, leading to exciting applications in noise reduction, imaging, sensing and navigation, as well as communications. | Hao Ge Min Yang Chu Ma Ming-Hui Lu Yan-Feng Chen Nicholas Fang Ping Sheng | 2018 | National Science Review2018，5，2： | 7 |
| 4 | Revisiting the Concentration Observations and Source Apportionment of Atmospheric Ammonia显示文摘While China’s Air Pollution Prevention and Control Action Plan on particulate matter since 2013 has reduced sulfate significantly,aerosol ammonium nitrate remains high in East China.As the high nitrate abundances are strongly linked with ammonia,reducing ammonia emissions is becoming increasingly important to improve the air quality of China.Although satellite data provide evidence of substantial increases in atmospheric ammonia concentrations over major agricultural regions,long-term surface observation of ammonia concentrations are sparse.In addition,there is still no consensus on whether agricultural or non-agricultural emissions dominate the urban ammonia budget.Identifying the ammonia source by nitrogen isotope helps in designing a mitigation strategy for policymakers,but existing methods have not been well validated.Revisiting the concentration measurements and identifying source apportionment of atmospheric ammonia is thus an essential step towards reducing ammonia emissions. | Yuepeng PAN Mengna GU Yuexin HE Dianming WU Chunyan LIU Linlin SONG Shili TIAN Xuemei LÜ Yang SUN Tao SONG Wendell WWALTERS Xuejun LIU Nicholas AMARTIN Qianqian ZHANG Yunting FANG Valerio FERRACCI Yuesi WANG | 2020 | Advances in Atmospheric Sciences2020，37，9： | 4 |
| 5 | Numerical study of a near-zero-index acoustic metamaterial显示文摘 | Yun Jing Jun Xu Nicholas X. Fang | 2012 | Physics Letters A2012，，45： | 1 |
| 6 | Operando Converting BiOCl into Bi_(2)O_(2)(CO_(3))_(x)Cl_(y) for Efficient Electrocatalytic Reduction of Carbon Dioxide to Formate显示文摘Bismuth-based materials(e.g., metallic, oxides and subcarbonate) are emerged as promising electrocatalysts for converting CO_(2) to formate. However, Bio-based electrocatalysts possess high overpotentials, while bismuth oxides and subcarbonate encounter stability issues. This work is designated to exemplify that the operando synthesis can be an effective means to enhance the stability of electrocatalysts under operando CO_(2)RR conditions. A synthetic approach is developed to electrochemically convert Bi^(O)Cl into Cl-containing subcarbonate(Bi_(2)O_(2)(CO_(3))_(x)Cl_(y)) under operando CO_(2)RR conditions. The systematic operando spectroscopic studies depict that BiOCl is converted to Bi_(2)O_(2)(CO_(3))_(x)Cl_(y) via a cathodic potential-promoted anion-exchange process. The operando synthesizedBi_(2)O_(2)(CO_(3))_(x)Cl_(y) can tolerate-1.0 V versus RHE, while for the wet-chemistry synthesized pure Bi_(2)O_(2)CO_(3),the formation of metallic Bio occurs at-0.6 V versus RHE. At-0.8 V versus RHE, Bi_(2)O_(2)(CO_(3))_(x)Cl_(y) can readily attain a FEHCOO-of 97.9%,much higher than that of the pure Bi_(2)O_(2)CO_(3)(81.3%). DFT calculations indicate that differing from the pure Bi_(2)O_(2)CO_(3)-catalyzed CO_(2)RR, where formate is formed via a *OCHO intermediate step that requires a high energy input energy of 2.69 eV to proceed, the formation of H COO-over Bi_(2)O_(2)(CO_(3))_(x)Cl_(y) has proceeded via a *COOH intermediate step that only requires low energy input of 2.56 eV. | Huai Qin Fu Junxian Liu Nicholas M.Bedford Yun Wang Joshua Wright Peng Fei Liu Chun Fang Wen Liang Wang Huajie Yin Dongchen Qi Porun Liu Hua Gui Yang Huijun Zhao | 2022 | Nano-Micro Letters2022，14，7： | 1 |
| 7 | Sub-diffraction-limited optical imaging with a silver superlens 显示文摘 | Fang Nicholas Lee Hyesog Sun Cheng | 2005 | Science (S0036-8075)2005，308，5742： | 1 |
| 8 | Subdiffraction-limited optical imaging with a silver superlens显示文摘 | Nicholas Fang Hyesog Lee Cheng Sun | 2005 | Science2005，308，5721： | 1 |
| 9 | Bulk decay of chlorine in water distribution systems显示文摘 | Nicholas B H Fang H John R W | 2003 | Water Res2003，129，1： | 1 |
| 10 | Imaging properties of a metameterial superlens 显示文摘 | FANG Nicholas ZHANG Xiang | 2003 | Apphed Physics Letters(S0003-6951)2003，82，2： | 1 |
| 11 | Terahertz Pasmon- i c High Pass Filter显示文摘 | Dongmin Wu Nicholas Fang Cheng Sun | 2003 | Appl Phys Lett2003，83，1： | 1 |
| 12 | Imaging properties of a metameterial superlens 显示文摘 | Fang Nicholas ZHANG Xiang | 2003 | Applied Physics Letters(S0003-6951)2003，82，2： | 1 |
| 13 | Bulk de- cay of chlorine in water distribution systems 显示文摘 | Nicholas B H Fang Hua West J R | 2003 | Journal of Water Resources Planning and Manage- ment2003，129，1： | 1 |
| 14 | Characterization of grapevine microR164 and its target genes显示文摘 | Xin Sun Nicholas Kibet Korir Jian Han Ling-Fei Shangguan Emrul Kayesh Xiang-Peng Leng Jing-Gui Fang | 2012 | Molecular Biology Reports2012，，10： | 1 |
| 15 | Bulk decay of chlorine in water distribution systems显示文摘 | Nicholas B H Fang H John R W | 2003 | Water Res2003，129，1： | 1 |
| 16 | High affinity soluble ILT2 receptor:a potent inhibitor of CD8^(+)T cell activation显示文摘Using directed mutagenesis and phage display on a soluble fragment of the human immunoglobulin superfamily receptor ILT2(synonyms:LIR1,MIR7,CD85j),we have selected a range of mutants with binding affinities enhanced by up to 168,000-fold towards the conserved region of major histocompatibility complex(MHC)class I molecules.Produced in a dimeric form,either by chemical cross-linking with bivalent polyethylene glycol(PEG)derivatives or as a genetic fusion with human IgG Fc-fragment,the mutants exhibited a further increase in ligand-binding strength due to the avidity effect,with resident half-times(t1/2)on the surface of MHC I-positive cells of many hours.The novel compounds antagonized the interaction of CD8 co-receptor with MHC I in vitro without affecting the peptide-specific binding of T-cell receptors(TCRs).In both cytokine-release assays and cell-killing experiments the engineered receptors inhibited the activation of CD8^(+)cytotoxic T lymphocytes(CTLs)in the presence of their target cells,with subnanomolar potency and in a dose-dependent manner.As a selective inhibitor of CD8^(+)CTL responses,the engineered high affinity ILT2 receptor presents a new tool for studying the activation mechanism of different subsets of CTLs and could have potential for the development of novel autoimmunity therapies. | Ruth K.Moysey Yi Li Samantha J.Paston Emma E.Baston Malkit S.Sami Brian J.Cameron Jessie Gavarret Penio Todorov Annelise Vuidepot Steven M.Dunn Nicholas J.Pumphrey Katherine J.Adams Fang Yuan Rebecca E.Dennis Deborah H.Sutton Andy D.Johnson Joanna E.Brewer Rebecca Ashfield Nikolai M.Lissin Bent K.Jakobsen | 2010 | Protein & Cell2010，1，12： | 1 |
| 17 | 3D direct printing of mechanical and biocompatible hydrogel meta-structures显示文摘Direct Ink Writing(DIW)has demonstrated great potential as a versatile method to 3D print multifunctional structures.In this work,we report the implementation of hydrogel meta-structures using DIW at room temperature,which seamlessly integrate large specific surface areas,interconnected porous characteristics,mechanical toughness,biocompatibility,and water absorption and retention capabilities.Robust but hydrophobic polymers and weakly crosslinked nature-origin hydrogels form a balance in the self-supporting ink,allowing us to directly print complex meta-structures without sacrificial materials and heating extrusion.Mechanically,the mixed bending or stretching of symmetrical re-entrant cellular lattices and the unique curvature patterns are combined to provide little lateral expansion and large compressive energy absorbance when external forces are applied on the printed meta-structures.In addition,we have successfully demonstrated ear,aortic valve conduits and hierarchical architectures.We anticipate that the reported 3D meta-structured hydrogel would offer a new strategy to develop functional biomaterials for tissue engineering applications in the future. | Lei Zhang Wenhan Lee Xinhao Li Yanhui Jiang Nicholas Xuanlai Fang Guohao Dai Yongmin Liu | 2022 | Bioactive Materials2022，7，4： | 0 |
| 18 | Single-cell RNA-sequencing and subcellular spatial transcriptomics facilitate the translation of liver microphysiological systems for regulatory application显示文摘Reducing the use of animal models in drug development and safety assessment has long been supported by the U.S.Food and Drug Administration(FDA).The report by Royal Society for the Prevention of Cruelty to Animals indicates that in 2020,experiments involved the use of over 100 million animals,with the United States leading the list by utilizing 20 million animals.Beyond ethical considerations associated with animal testing and the costs in terms of time and money,animal models are not always effective in predicting human reactions to drug exposure.While animal testing has been the traditional method for assessing the safety and efficacy of drugs. | Dan Li Zhou Fang Qiang Shi Nicholas Zhang Binsheng Gong Weida Tong Ahmet F.Coskun Joshua Xu | 2023 | Journal of Pharmaceutical Analysis2023，13，7： | 0 |
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