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| 1 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 2 | 内皮细胞在冠状动脉张力调节中的作用显示文摘自1980年Furchgott和Zawadzki首先报道内皮细胞在血管张力变化中的作用以来,该领域的研究有了很大进展。现已证实,内皮细胞调节血管张力的主要机制是合成和释放血管松弛因子(EDRF)及收缩因子(EDCF)。本文旨在回顾近年来的主要研究成果,并重点阐述内皮细胞在冠状动脉(冠脉)张力调节中的作用。 | 王乐信 Thomas F.Lüscher | 1992 | 中国循环杂志1992，7，3： | 2 |
| 3 | Molecular mechanisms of vascular effects of High‐density lipoprotein: alterations in cardiovascular disease显示文摘 | ChristianBesler Thomas F.Lüscher UlfLandmesser | 2012 | EMBO Mol Med2012，，4： | 2 |
| 4 | 查看详情显示文摘 | Lopez J.G Rodriguea V.Y Roces L Granda S.G. Martinez A. Garcia A.G. Castro G.R. Villacorta F.J. Iglesias M.J. Ortiz F.L | | 0，，： | 1 |
| 5 | Individual differences and age effects in a dichotic informational masking paradigm显示文摘 | Wightman F.L Kistler D.J O'Bryan A | | 0，，01： | 1 |
| 6 | 查看详情显示文摘 | Gong F.L Zhao C.G Feng M Qin H.L.and Yang M.S | | 0，，： | 1 |
| 7 | Human Memory显示文摘 | CRAIK F.L M | | 0，，： | 1 |
| 8 | 查看详情显示文摘 | Gong F.L Feng M Zhao C.G Zhang S.M.and Yang M.S | | 0，，： | 1 |
| 9 | A comparison of three learning strategies for ESL vocabulary acquisition显示文摘 | Brown T.S Perry F.L | | 0，，04： | 1 |
| 10 | 查看详情显示文摘 | Gong F.L Feng M Zhao C.G Zhang S.M.and Yang M.S | | 0，，： | 1 |
| 11 | Content-Based Instruction for Foreign Language Classroom显示文摘 | Stroller F.L Stryker S.B | | 0，，： | 1 |
| 12 | Microstructure of Ni-Al-Diamond Composite Fabricated by Self-Propagating High Temperature Synthesis显示文摘 | Zhang F.L Yuan Hui Wang Cheng Yong Fu K.X. Zhou Y.M | 2005 | Key Engineering Materials2005，，291： | 1 |
| 13 | 查看详情显示文摘 | Xie F.L Qin Y Tang J | | 0，，11： | 1 |
| 14 | Design energy input spectra for moderate‐seismicity regions显示文摘 | A.Benavent‐Climent L. G.Pujades F.López‐Almansa | 2002 | Earthquake Engng Struct Dyn2002，，5： | 1 |
| 15 | Freedom from secondary interventions to treat stenotic disease after percutaneous transluminal angioplasty of infrarenal aorta: long-term results显示文摘 | J.P.P.M de Vries D.A.F van Den Heuvel J.A Vos J.C van Den Berg F.L Moll | 2004 | Journal of Vascular Surgery2004，，2： | 1 |
| 16 | Sol–gel nonhydrolytic synthesis of a hybrid organic–inorganic electrolyte for application in lithium-ion devices显示文摘 | F.L Souza P.R Bueno E Longo E.R Leite | 2003 | Solid State Ionics2003，，1： | 1 |
| 17 | Urban Poverty and Marginalization under Market Transition:The Case of Chinese Cities显示文摘 | Wu F.L | | 0，，02： | 1 |
| 18 | Optical excitations of boron nitride ribbons and nanotubes显示文摘 | R.B Chen C.P Chang F.L Shyu M.F Lin | 2002 | Solid State Communications2002，，8： | 1 |
| 19 | 查看详情显示文摘 | Dong Y. B Jiang Y. Y Li J Ma J.P Liu F.L Tang B Huang R.Q Batten S.R | | 0，，： | 1 |
| 20 | the Changing Dynamics of Employment Relations in China:An Evaluation of the Rising Level of Labor Disputes显示文摘 | Cooke F.L | | 0，，01： | 1 |
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