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| 1 | 论思维和STEM教育显示文摘随着全球化的STEM教育领域的迅速发展,各国对跨学科研究以及开发更新、更深入的STEM教育的学术研究的呼声也越来越高.文章聚焦思维这个话题,首先从历史发展的视角,简要概括分析了有关思维的不同观点,包括哲学的、心理的和学科的,揭示了思维概念和研究的历史传承.但在新兴的STEM教育背景下,思维需要重新概念化.文章提出了思维是多元的观点,初步探讨了STEM融合教育的这种方式,能够为学生提供充分的机会来有效地发展多元思维模式,并对未来关于思维的研究提出了可能的新研究领域和方向. | 李业平 SCHOENFELD A H DISESSA A A GRAESSER A C BENSON L C ENGLISH L D DUSCHL R A | 2019 | 数学教育学报2019，0，3： | 10 |
| 2 | Characterization of colonic dendritic cells in normal and colitic mice显示文摘AIM: Recent studies demonstrating the direct involvement of dendritic cells (DC) in the activation of pathogenic T cells in animal models of inflammatory bowel disease identify DC as important antigen presenting cells in the colon. However, very little is known about the properties of colonic DC.METHODS: Using immunohistochemistry, electron microscopy and flow cytometry we have characterized and compared colonic DC in the colon of healthy animals and interleukin-2-deficient (IL2-/-) mice that develop colitis.RESULTS: In the healthy colon, DC resided within the lamina propria and in close association with the basement membrane of colonic villi. Type 1 myeloid (CD11c+, CD11b+,B220-, CD8α-) DC made up the largest (40-45%) population and all DC expressed low levels of CD80, CD86, and CD40,and had high endocytic activity consistent with an immature phenotype. In colitic IL2-/- mice, colonic DC numbers increased four- to five-fold and were localized within the epithelial layer and within aggregates of T and B cells. They were also many more DC in mesenteric lymph nodes (MLN).The majority (>85%) of DC in the colon and MLN of IL2-/-mice were type 1 myeloid, and expressed high levels of MHC class Ⅱ, CD80, CD86, CD 40, DEC 205, and CCR5molecules and were of low endocytic activity consistent with mature DC.CONCLUSION: These findings demonstrate striking changes in the number, distribution and phenotype of DC in the inflamed colon. Their intimate association with lymphocytes in the colon and draining lymph nodes suggest that they may contribute directly to the ongoing inflammation in the colon. | Sheena M Cruickshank Nicholas R English Peter J Felsburg Simon R Carding | 2005 | World Journal of Gastroenterology2005，11，40： | 3 |
| 3 | Selection of Peptides with Semiconductor Binding Specificity for Directed Nanocrystal Assembly 显示文摘 | Whaley S R English D S Hu E L | 2000 | Nature2000，405，6787： | 1 |
| 4 | A geographic information system-based modeling system for evaluating the cost of delivered energy crop feedstock显示文摘 | Graham R L English B C Noon C E | 2000 | Biomass and Bioenergy2000，18，4： | 1 |
| 5 | RheologyAnd photo-cross-linking of thiol-ene polymers 显示文摘 | Bor-Sen C English R J SaadA K | 1996 | Macromolecules1996，29，16： | 1 |
| 6 | W-Band (75-110 GHz) Microstrip Components显示文摘 | Chang K English D M Tahim R S etal | 1985 | IEEE Trans Microwave Theory & Tech1985，33，12： | 1 |
| 7 | Monitoring Automatically Controlled Processes Using Statistical Control Charts显示文摘 | Gültekin M Elsayed E A English J R | 2002 | Int J of Production Research2002，40，10： | 1 |
| 8 | Evaluation of creep feeding using a Highlydigestible diet for litters weaned at 4 weeks of age显示文摘 | English P R Robb C M | 1980 | Animal Production1980，30，： | 1 |
| 9 | Low dose transderrnal testosterone therapy improves angina threshold in men with chronic stable angina, a randomized, double-blind, placebo-controlled study显示文摘 | English K M Steeds R P Jones T H | 2000 | Circulation2000，102，16： | 1 |
| 10 | Effect of physical activity and body size on survival after diagnosis with colorectal cancer显示文摘 | HAYDON A MACINNIS R J ENGLISH D R | 2006 | Gut2006，55，1： | 1 |
| 11 | National Ignition Facility main laser light analysis and control显示文摘 | John L Miller R Edward English Jr John C Schweyen | 1998 | SPIE1998，3492，： | 1 |
| 12 | Genetic variation of wild and hatchery populations of the Pacific oyster,Crassostrea gigas (Thunberg),in Australia显示文摘 | English L J Maguire G B Ward R B | 2000 | Aquaculture2000，187，： | 1 |
| 13 | Dothiorella canker,a new disease of almond trees in California显示文摘 | English H Davis J R Devay J E | 1966 | Phytopathology1966，56，： | 1 |
| 14 | Teaching undergraduate students community nursing: using action research to increase engagement and learning显示文摘 | Seib C English R Barnard A | 2011 | J Nurs Educ2011，50，9： | 1 |
| 15 | Consensus state- ment on the management of chronic hand eczema 显示文摘 | English J Aldridge R Gawkrodger D J | 2009 | Clin Exp Dermatol2009，34，7： | 1 |
| 16 | Genetic improvement of the Pacific oyster Crassostrea gigas(Thunberg)in Australia显示文摘 | Ward R D English L J McGoldrick D J Maguire G B Nell J A Thompson P A | | 0，，1： | 1 |
| 17 | Keloids and hypertrophic scars显示文摘 | English R S Shenefelt P D | 1999 | Dermatol Surg1999，25，25： | 1 |
| 18 | Effect of dietary fibre and feeding system on activity and oral behaviours on group- housed gihs显示文摘 | Brouns F Edwards F English R et a/ | 1994 | Appl AnimalBehavior Science1994，39，： | 1 |
| 19 | Selection of peptides with semiconductor binding opecificity for directed nanocrystal assembly显示文摘 | English D S Hu Evelynl | 2000 | Nature2000，405，8： | 1 |
| 20 | 查看详情显示文摘 | AGRAWAL S ENGLISH N J THAMPI K R | | 0，，： | 1 |
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