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| 1 | Acute renal dysfunction in liver diseases显示文摘Renal dysfunction is common in liver diseases,either as part of multiorgan involvement in acute illness or secondary to advanced liver disease.The presence of renal impairment in both groups is a poor prognostic indicator.Renal failure is often multifactorial and can present as pre-renal or intrinsic renal dysfunction.Obstructive or post renal dysfunction only rarely complicates liver disease.Hepatorenal syndrome(HRS)is a unique form of renal failure associated with advanced liver disease or cirrhosis,and is characterized by functional renal impairment without significant changes in renal histology.Irrespective of the type of renal failure,renal hypoperfusion is the central pathogenetic mechanism,due either to reduced perfusion pressure or increased renal vascular resistance.Volume expansion,avoidance of precipitating factors and treatment of underlying liver disease constitute the mainstay of therapy to prevent and reverse renal impairment.Splanchnic vasoconstrictor agents,such as terlipressin,along with volume expansion,and early placement of transjugular intrahepatic portosystemic shunt(TIPS)may be effective in improving renal function in HRS.Continuous renal replacement therapy(CRRT)and molecular absorbent recirculating system(MARS)in selected patients may be life saving while awaiting liver transplantation. | Alex P Betrosian Banwari Agarwal Emmanuel E Douzinas | 2007 | World Journal of Gastroenterology2007，13，42： | 14 |
| 2 | Molecular markers(PECAM-1,ICAM-3,HLA-DR)determine prognosis in primary non-Hodgkin's gastric lymphoma patients显示文摘瞄准:与主要 non-Hodgkin 的胃的淋巴瘤在病人调查 PECAM-1, ICAM-3 和 HLA 医生抗原的预示的意义。方法:我们免疫组织化学地在 36 个 B 房间麦芽类型主要胃的淋巴瘤病人学习了 PECAM-1, ICAM-3 和 HLA 医生抗原表示。十非恶意并且十个健康胃的织物标本被用作控制。Clinicopathological 和幸存数据与染色的结果被相关。结果:HLA 医生抗原表示在 33 个胃的淋巴瘤病人(91.7%) 和 6 个非恶意的病人(54.5%) 被检测。PECAM-1 染色了 10 个病人(27.8%) 的肿瘤房间, 9 个病人(25%) 的 endothelial 并且煽动性有良性的胃的疾病的 4 个病人(40%) 渗入。ICAM-3 表示在 17 个病人(47.2%) 的肿瘤房间上被观察,当 5 个非恶意的病人(50%) 被染色时积极也。任何一个都没为任何学习的基因健康控制被染色。在里面多,变量分析, HLA 医生抗原和 PECAM-1 被证明是与联系的统计上重要的独立预示的因素一赞成并且不利预后分别地(P=0.009 和 P=0.003 ) 。在 univariate 分析, PECAM-1 (+)/ICAM-3 (-) 和 HLA 医生(-)/ICAM-3 (-) 病人与确切相反的基因表示模式与那些相比展出了显著地减少的全面幸存(P=0.0041 和 P=0.0091,分别地) 。是 HLA 医生(+)/ICAM-3 (+)/PECAM-1 (-)(n=8 ) 的那些病人让显著地更高的幸存与这个组(n=24 )(P=0.0289 ) 的其余部分相比评价。结论:PECAM-1, ICAM-3 和 HLA 医生分别地是肿瘤扩大潜力和主人免疫者监视的代表性的标记。他们的联合使用可以帮助我们识别能得益于更好攻击的治疗学的协议的高风险的病人。 | Alexander Darom Ilias P Gomatos Emmanuel Leandros Emmu Chatzigianni Dimitris Panousopoulos Manousos M Konstadoulakis George Androulakis | 2006 | World Journal of Gastroenterology2006，12，12： | 4 |
| 3 | Solitary fibrous tumor of the liver expressing CD34 and vimentin:A case report显示文摘A case of a successfully treated solitary fibrous tumor (SFT) of the liver is reported.An 82-year-old female presented with left upper abdominal discomfort,a firm mass on palpation,and imaging studies revealed a large tumor,15 cm in diameter,arising from the left lobe of the liver.A formal left hepatectomy was performed.Microscopic evaluation showed spindle and fibroblast-like cells within the collagenous stroma.Immunohistochemistry disclosed diffuse CD34 and positive vimentin,supporting the diagnosis of a benign SFT.The patient remained well 21 months after surgery.SFT of the liver is a very rare neoplasm of mesenchymal origin.In most cases it is a benign lesion,although some may have malignant histological features and recur locally or metastasize.With less than 30 reported cases in the literature,little can be said regarding its natural history or the benefits of adjuvant radiochemotherapy.Complete surgical resection remains the cornerstone of its treatment. | Dimitris P Korkolis Katerina Apostolaki Chrysanthi Aggeli George Plataniotis Emmanuel Gontikakis Dimitra Volanaki Maria Sebastiadou Dimitris Dimitroulopoulos Dimitris Xinopoulos George N Zografos Perikles P Vassilopoulos | 2008 | World Journal of Gastroenterology2008，14，40： | 3 |
| 4 | Fluid balance concepts in medicine:Principles and practice显示文摘The regulation of body fluid balance is a key concern in health and disease and comprises three concepts. The first concept pertains to the relationship between total body water(TBW) and total effective solute and is expressed in terms of the tonicity of the body fluids. Disturbances in tonicity are the main factor responsible for changes in cell volume, which can critically affect brain cell function and survival. Solutes distributed almost exclusively in the extracellular compartment(mainly sodium salts) and in the intracellular compartment(mainly potassium salts) contribute to tonicity, while solutes distributed in TBW have no effect on tonicity. The second body fluid balance concept relates to the regulation and measurement of abnormalities of sodium salt balance and extracellular volume. Estimation of extracellular volume is more complex and error prone than measurement of TBW. A key function of extracellular volume, which is defined as the effective arterial blood volume(EABV), is to ensure adequate perfusion of cells and organs. Other factors, including cardiac output, total and regional capacity of both arteries and veins, Starling forces in the capillaries, and gravity also affect the EABV. Collectively, these factors interact closely with extracellular volume and some of them undergo substantial changes in certain acute and chronic severe illnesses. Their changes result not only in extracellular volume expansion, but in the need for a larger extracellular volume compared with that of healthy individuals. Assessing extracellular volume in severe illness is challenging because the estimates of this volume by commonly used methods are prone to large errors in many illnesses. In addition, the optimal extracellular volume may vary from illness to illness, is only partially based on volume measurements by traditional methods, and has not been determined for each illness. Further research is needed to determine optimal extracellular volume levels in several illnesses. For these reasons, extracellular volume in severe illness merits a separate third concept of body fluid balance. | Maria-Eleni Roumelioti Robert H Glew Zeid J Khitan Helbert Rondon-Berrios Christos P Argyropoulos Deepak Malhotra Dominic S Raj Emmanuel I Agaba Mark Rohrscheib Glen H Murata Joseph I Shapiro Antonios H Tzamaloukas | 2018 | World Journal of Nephrology2018，7，1： | 3 |
| 5 | Reasons of PEG failure to eliminate gastroesophageal reflux in mechanically ventilated patients显示文摘AIM:To investigate factors predicting failure of percutaneous endoscopic gastrostomy(PEG)to eliminate gastroesophageal reflux(GER). METHODS:Twenty-nine consecutive mechanically ventilated patients were investigated.Patients were evaluated for GER by pH-metry pre-PEG and on the 7th post-PEG day.Endoscopic and histologic evidence of reflux esophagitis was also carried out.A beneficial response to PEG was considered when pH-metry on the 7th post-PEG day showed that GER was below 4%. RESULTS:Seventeen patients responded(RESP group)and 12 did not respond(N-RESP)to PEG.The mean age,sex,weight and APACHEⅡscore were similar in both groups.GER(%)values were similar in both groups at baseline,but were significantly reduced in the RESP group compared with the N-RESP group on the 7th post-PEG day[2.5(0.6-3.8)vs 8.1(7.4-9.2, P<0.001)].Reflux esophagitis and the gastroesophageal flap valve(GEFV)grading differed significantly between the two groups(P=0.031 and P=0.020, respectively).Histology revealed no significant differences between the two groups.CONCLUSION:Endoscopic grading of GEFV and the presence of severe reflux esophagitis are predisposing factors for failure of PEG to reduce GER in mechanically ventilated patients. | Emmanuel E Douzinas Ilias Andrianakis Olga Livaditi Dimitrios Bakos Katerina Flevari Nikos Goutas Dimitrios Vlachodimitropoulos Marios-Konstantinos Tasoulis Alex P Betrosian | 2009 | World Journal of Gastroenterology2009，15，43： | 2 |
| 6 | Visual censuses of tropical fish aggregations on artificial reefs : slate versus video recording techniques 显示文摘 | Emmanuel T Pascale C Karine P | 2005 | Journal of Experimental Marine Biology and Ecology2005，315，： | 1 |
| 7 | Evolutionary affinities of the enigmatic saola (Pseudoryx nghetinhensis) in the context of the molecular phylogeny of Bovidae显示文摘 | Hassanin Alexandre Douzery Emmanuel J. P | 1999 | Proceedings of the Royal Society B: Biological Sciences1999，，1422： | 1 |
| 8 | The incidence of drugdiagnostic test interterencesin outpatients显示文摘 | Munzenberger P Emmanuel S | 1971 | Am J Hosp Pharm1971，28，10： | 1 |
| 9 | Effect of the Nature of Carbon Catalysts on Glyphosate Synthesis显示文摘 | CHATERINE P EMMANUEL L HEDI L et ol | 1999 | Journal of Catalyst1999，182，： | 1 |
| 10 | Multi-institutional validation of a symptom based classification for renal cell carcinoma 显示文摘 | JEAN-JACQUES P EMMANUELLE L LUCA C | 2004 | J Urol2004，172，： | 1 |
| 11 | An overview of HIV-1 co-receptor function and its inhibitors 显示文摘 | Emmanuel GC Marjan P Daniah AD | 2000 | PANS LINE2000，97，11： | 1 |
| 12 | Benign par-oxysmal positional vertigo : 10-year experience in treating592 patients with cannaiith repositioning procedure 显示文摘 | Emmanuel P Theognosia C Minas T | 2005 | Laryngoscope2005，115，9： | 1 |
| 13 | The role of a pharmacist on the paediatric unit of a generate hospital显示文摘 | Muzenberger P Emmanuel S I-Ieins M | 1972 | Am J Hosp Pharm1972，29，9： | 1 |
| 14 | Synthesis and char acterization of unsaturated polyester and phenolic resin nanocomposites显示文摘 | Jongdoo L Emmanuel P G | 1997 | Polymer Preprint1997，38，2： | 1 |
| 15 | Thoracoscopic excision of mediastinal bronchogenic cysts:results in 20 cades显示文摘 | Emmanuel M Francois P Jacques A | 2000 | Ann Thorac Surg2000，69，： | 1 |
| 16 | Rheology of end-tethered polymer layered silicate nanocomposites显示文摘 | Krishnamoorti Giannelis Emmanuel P | 1997 | Macromolecules1997，30，14： | 1 |
| 17 | Journal club: acute abdominal pain in elderly patients : effect of radiologist awareness of clinicobiologic information on CT accuracy显示文摘 | Ingrid M Chakib A Emmanuelle B P | 2013 | American Journal of Roentgenology2013，201，6： | 1 |
| 18 | Comparative growth and welfare in rainbow trout reared in recirculating and flow through rearing systems显示文摘 | EMMANUELLE R JEANINE P NICOLAS L | 2009 | Aquacultural Engineering2009，40，2： | 1 |
| 19 | Bilingual Language Representation and Cognitive Processes in Translation显示文摘 | HatzidakiA & Emmanuel M P | 2008 | Applied Psycholin-guistics2008，，29： | 1 |
| 20 | Interlayer structure and molecular environment of alkylammonium layered silicates显示文摘 | Richard A Vaia Rachel K Teukolsky Emmanuel P Giannelis | 1994 | Chem Mater1994，6，7： | 1 |
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