|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Biliary leakage following pancreaticoduodenectomy:Prevalence,risk factors and management显示文摘Background: Few studies investigated biliary leakage after pancreaticoduodenectomy(PD) especially when compared to postoperative pancreatic fistula(POPF). This study was to determine the incidence of biliary leakage after PD, predisposing factors of biliary leakage, and its management. Methods: We retrospectively studied all patients who underwent PD from January 2008 to December 2017 at Gastrointestinal Surgery Center, Mansoura University, Egypt. According to occurrence of postoperative biliary leakage, patients were divided into two groups. Group(1) included patients who developed biliary leakage and group(2) included patients without identified biliary leakage. The preoperative data, operative details, and postoperative morbidity and mortality were analyzed. Results: The study included 555 patients. Forty-four patients(7.9%) developed biliary leakage. Ten patients(1.8%) had concomitant POPF. Multivariate analysis identified obesity and time needed for hepaticojejunostomy reconstruction as independent risk factors of biliary leakage, and no history of preoperative endoscopic retrograde cholangiopancreatiography(ERCP) as protective factor. Biliary leakage from hepaticojejunostomy after PD leads to a significant increase in development of delayed gastric emptying, and wound infection. The median hospital stay and time to resume oral intake were significantly greater in the biliary leakage group. Non-surgical management was needed in 40 patients(90.9%). Only 4 patients(9.1%) required re-exploration due to biliary peritonitis and associated POPF. The mortality rate in the biliary leakage group was significantly higher than that of the non-biliary leakage group(6.8% vs 3.9%, P = 0.05). Conclusions: Obesity and time needed for hepaticojejunostomy reconstruction are independent risk factors of biliary leakage, and no history of preoperative ERCP is protective factor. Biliary leakage increases the risk of morbidity and mortality especially if concomitant with POPF. However, biliary leakage can be conservatively managed in majority of cases. | Ayman El Nakeeb Mohamed El Sorogy Hosam Hamed Rami Said Mohamad Elrefai Helmy Ezzat Waleed Askar Ahmed M Elsabbagh | 2019 | Hepatobiliary & Pancreatic Diseases International2019，18，1： | 4 |
| 2 | Neural correlates of eye gaze processing in the infant broader autism phenotype显示文摘 | Elsabbagh M Volein A Csibra G | | 0，，01： | 1 |
| 3 | Global prevalence of autism and other pervasive developmental disorders 显示文摘 | Elsabbagh M Divan G Koh YJ | 2012 | Autism Research2012，5，： | 1 |
| 4 | The Role of Prosody in Dis-course Processing显示文摘 | Cohen H Douaire J Elsabbagh M | 2001 | Brain and Cognition2001，46，12： | 1 |
| 5 | Global prevalence of autism and other pervasive developmental disorders显示文摘 | Elsabbagh M Divan G Koh YJ | 2012 | Autism Res2012，5，3： | 1 |
| 6 | Understanding goal-directed human actions and physical causality:The role of mother-infant interaction显示文摘 | Hohenberger A Elsabbagh M Serres J | 2012 | Infant Behavior and Development2012，35，4： | 1 |
| 7 | Temperament in the first 2 years of life in infants at high-risk for autism spectrum disorders显示文摘 | Clifford SM Hudry K Elsabbagh M | 2013 | J Autism Dev Disord2013，43，3： | 1 |
| 8 | Global prevalence of autism and other pervasive developmental disorders显示文摘 | Elsabbagh M Divan G Koh Y J | 2012 | Au- tism Res2012，5，3： | 1 |
| 9 | In search of biomarkers for autism:scientific,social and ethical challenges显示文摘 | Walsh P Elsabbagh M Bolton P | | 0，，10： | 1 |
| 10 | Global Prevalence of Autism and Other Pervasive Developmental Disorders 显示文摘 | Disorders Elsabbagh M Divan G | 2012 | Autism Res2012，5，3： | 1 |
| 11 | Neural correlates of eye gaze processing in the infant broader autism phenotype 显示文摘 | Elsabbagh M Volein A Csibra G | 2009 | Biol Psychia2009，65，1： | 1 |
| 12 | Globalprevalence of autism and other pervasive developmental disorders显示文摘 | ELSABBAGH M DIVAN G KOH Y J | 2012 | Autism Res2012，5，3： | 1 |
| 13 | Global prevalence of au-tism and other pervasive developmental disorders显示文摘 | Elsabbagh M Divan G Koh YJ | 2012 | Autism Res2012，5，3： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员