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| 1 | Biliary leakage following pancreaticoduodenectomy:Prevalence,risk factors and management显示文摘Background: Few studies investigated biliary leakage after pancreaticoduodenectomy(PD) especially when compared to postoperative pancreatic fistula(POPF). This study was to determine the incidence of biliary leakage after PD, predisposing factors of biliary leakage, and its management. Methods: We retrospectively studied all patients who underwent PD from January 2008 to December 2017 at Gastrointestinal Surgery Center, Mansoura University, Egypt. According to occurrence of postoperative biliary leakage, patients were divided into two groups. Group(1) included patients who developed biliary leakage and group(2) included patients without identified biliary leakage. The preoperative data, operative details, and postoperative morbidity and mortality were analyzed. Results: The study included 555 patients. Forty-four patients(7.9%) developed biliary leakage. Ten patients(1.8%) had concomitant POPF. Multivariate analysis identified obesity and time needed for hepaticojejunostomy reconstruction as independent risk factors of biliary leakage, and no history of preoperative endoscopic retrograde cholangiopancreatiography(ERCP) as protective factor. Biliary leakage from hepaticojejunostomy after PD leads to a significant increase in development of delayed gastric emptying, and wound infection. The median hospital stay and time to resume oral intake were significantly greater in the biliary leakage group. Non-surgical management was needed in 40 patients(90.9%). Only 4 patients(9.1%) required re-exploration due to biliary peritonitis and associated POPF. The mortality rate in the biliary leakage group was significantly higher than that of the non-biliary leakage group(6.8% vs 3.9%, P = 0.05). Conclusions: Obesity and time needed for hepaticojejunostomy reconstruction are independent risk factors of biliary leakage, and no history of preoperative ERCP is protective factor. Biliary leakage increases the risk of morbidity and mortality especially if concomitant with POPF. However, biliary leakage can be conservatively managed in majority of cases. | Ayman El Nakeeb Mohamed El Sorogy Hosam Hamed Rami Said Mohamad Elrefai Helmy Ezzat Waleed Askar Ahmed M Elsabbagh | 2019 | Hepatobiliary & Pancreatic Diseases International2019,18,1: | 4 |
| 2 | 孤独症谱系障碍的风险因素与预后联系:有恢复的证据吗?显示文摘孤独症谱系障碍(本文指孤独症)对不同的个体产生的影响不同,是几种重叠的神经发育疾病之一。这种变异性是生物学和非生物学风险因素之间动态相互作用的结果,随着时间的推移,会导致个体之间的分化差异增加。尽管分化一直持续到成年,但婴儿期是大脑和行为迅速发展,以及孤独症症状和体征最初出现的时期。本文将详述导致孤独症和重叠神经发育疾病的机制及进展。研究还绘制了某些风险人群(即孤独症儿童的同胞弟妹和/或因发育问题而转诊的婴儿)的大脑和行为发展轨迹,有助于在婴儿出现症状之前提高早期识别和确定针对性干预措施的可行性。然而,对于该病我们仍然存在关键性的知识鸿沟,例如尚未发现可能减轻风险影响的保护因素(生物或环境学方面的)。此外,需要进一步研究风险因素和结局之间联系的动态机制,包括恢复的过程,这可能解释了为什么一些有孤独症风险的个体取得了比预期更好的结果。弥合这些知识差距,将有助于找到早期识别和干预的手段,反映从风险到结果的动态发展路径。 | Mayada Elsabbagh 陈静(译) 何燕玲(校) | 2020 | 英国医学杂志中文版2020,23,8: | 3 |
| 3 | 基于GA-RBF神经网络和sEMG的下肢动作识别方法研究显示文摘为了提高人体肌电信号对于下肢动作识别的准确率,提出一种基于遗传算法(GA)优化的径向基(RBF)神经网络分类模型。通过采集人体日常8种下肢动作的表面肌电信号并选择“sym6”系小波函数对肌电信号进行滤波预处理,使用主成分分析法(PCA)对时频域特征降维,把特征向量输入GA算法优化的RBF神经网络进行训练和识别。实验结果表明,该方法对同一受试者8种下肢动作的平均识别率为94.00%±0.45%;对15位不同受试下肢动作识别率达到89.30%,比传统BP神经网络的识别准确率提高11.8%,预测时间缩短6 s。所提出的方法为肌电信号应用于下肢智能康复机器人的意图识别研究提供参考,有助于病人的康复。 | 张鹏 张峻霞 刘瑞恒 Ahmed Mohamed Moneeb Elsabbagh | 2022 | 中国生物医学工程学报2022,41,1: | 1 |
| 4 | Neural correlates of eye gaze processing in the infant broader autism phenotype显示文摘 | Elsabbagh M Volein A Csibra G | | 0,,01: | 1 |
| 5 | Global prevalence of autism and other pervasive developmental disorders 显示文摘 | Elsabbagh M Divan G Koh YJ | 2012 | Autism Research2012,5,: | 1 |
| 6 | The Role of Prosody in Dis-course Processing显示文摘 | Cohen H Douaire J Elsabbagh M | 2001 | Brain and Cognition2001,46,12: | 1 |
| 7 | Neurotoxicologic sequelae of tributyltin intoxication inrats 显示文摘 | ELSABBAGH H S MOUSSA S Z EH-TAWIL O S | 2002 | Pharmacological Research2002,45,3: | 1 |
| 8 | Global prevalence of autism and other pervasive developmental disorders显示文摘 | Elsabbagh M Divan G Koh YJ | 2012 | Autism Res2012,5,3: | 1 |
| 9 | Understanding goal-directed human actions and physical causality:The role of mother-infant interaction显示文摘 | Hohenberger A Elsabbagh M Serres J | 2012 | Infant Behavior and Development2012,35,4: | 1 |
| 10 | Temperament in the first 2 years of life in infants at high-risk for autism spectrum disorders显示文摘 | Clifford SM Hudry K Elsabbagh M | 2013 | J Autism Dev Disord2013,43,3: | 1 |
| 11 | Monotonic and cyclic behavior of concrete-filled steel-tube beam-columns considering local buckling effect显示文摘 | Zubydan A H ElSabbagh A I | | 0,,04: | 1 |
| 12 | Monotonic and cyclic behavior of concrete-filled steel-tube beam-columns considering local buckling effect显示文摘 | Ahmed H. Zubydan Ashraf I. ElSabbagh | 2010 | Thin-Walled Structures2010,,4: | 1 |
| 13 | 显示文摘 | Elnady T Elsabbagh A Akl W | 2009 | Applied Physics Letters2009,94,13: | 1 |
| 14 | Global prevalence of autism and other pervasive developmental disorders显示文摘 | Elsabbagh M Divan G Koh Y J | 2012 | Au- tism Res2012,5,3: | 1 |
| 15 | In search of biomarkers for autism:scientific,social and ethical challenges显示文摘 | Walsh P Elsabbagh M Bolton P | | 0,,10: | 1 |
| 16 | Global Prevalence of Autism and Other Pervasive Developmental Disorders 显示文摘 | Disorders Elsabbagh M Divan G | 2012 | Autism Res2012,5,3: | 1 |
| 17 | Neural correlates of eye gaze processing in the infant broader autism phenotype 显示文摘 | Elsabbagh M Volein A Csibra G | 2009 | Biol Psychia2009,65,1: | 1 |
| 18 | Quenching of Acoustic Bandgaps by Flow Noise显示文摘 | Elnady T Elsabbagh A Akl W | 2009 | Applied Physics Letters2009,94,13: | 1 |
| 19 | Quenching of Acoustic Bandgaps by Flow Noise显示文摘 | Elnady T Elsabbagh A Akl W | 2009 | Applied Physics Letters2009,94,13: | 1 |
| 20 | Globalprevalence of autism and other pervasive developmental disorders显示文摘 | ELSABBAGH M DIVAN G KOH Y J | 2012 | Autism Res2012,5,3: | 1 |